Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr6 | 31545278 | . | G | A | CCDS4702.1:NM_000594.3:c.666gaG>gaA_NP_000585.2:p.222E>E | Homo sapiens tumor necrosis factor (TNF), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6op0 | 1 | P01375 | 99.37 | 6e-115 |
X-RAY |
2019-12-25 | GLU | A:147 | A:146 | 61.0 | NA | S | -115.2 | 168.7 | 44.0 | NA | NA |
B:P01375:NA |
HOH |
4.886 |
O |
O |
|
GLU | B:147 | B:146 | 151.0 | 0.795 | S | -109.3 | 172.1 | 84.0 | 0.442 | 0.353 |
C:P01375:0.353 |
HOH |
2.587 |
OE1 |
O |
||||||||
GLU | C:147 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
7kp9 | 1 | P01375 | 99.37 | 6e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 138.0 | 0.726 | S | -156.1 | 152.2 | 106.0 | 0.558 | 0.168 |
B:P01375:0.168 |
HOH |
3.000 |
CA |
O |
|
GLU | B:147 | B:146 | 57.0 | NA | S | -133.9 | 161.2 | 40.0 | NA | NA |
C:P01375:NA |
HOH |
2.823 |
O |
O |
||||||||
GLU | C:147 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
7kpa | 1 | P01375 | 99.37 | 6e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 51.0 | NA | S | -148.3 | 150.5 | 38.0 | NA | NA |
B:P01375:NA |
HOH |
2.911 |
O |
O |
|
GLU | B:147 | B:146 | 149.0 | 0.784 | S | -115.1 | 167.3 | 86.0 | 0.453 | 0.331 |
C:P01375:0.332 |
HOH |
3.003 |
O |
O |
||||||||
GLU | C:147 | C:146 | 33.0 | NA | -91.3 | 85.7 | 27.0 | NA | NA |
A:P01375:NA |
|||||||||||||
7kpb | 1 | P01375 | 99.37 | 6e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 144.0 | 0.758 | S | -135.9 | 163.3 | 42.0 | 0.221 | 0.537 |
E:P19438:0.395 B:P01375:0.153 |
HOH |
3.538 |
C |
O |
|
GLU | B:147 | B:146 | 140.0 | 0.737 | S | -121.9 | 161.9 | 38.0 | 0.2 | 0.537 |
C:P01375:0.174 D:P19438:0.405 |
GOL GOL HOH |
2.715 7.892 7.780 |
OE1 OE1 O |
O2 O1 O |
||||||||
GLU | C:147 | C:146 | 89.0 | 0.468 | -79.5 | 76.9 | 17.0 | 0.089 | 0.379 |
F:None:0.258 G:None:0.137 A:P01375:0.058 |
HOH |
6.508 |
O |
O |
|||||||||
5mu8 | 1 | P01375 | 100.0 | 9e-115 |
X-RAY |
2017-03-29 | GLU | A:148 | A:146 | 87.0 | 0.458 | T | -72.5 | 66.3 | 87.0 | 0.458 | 0.0 | ||||||
GLU | B:148 | B:146 | 139.0 | 0.732 | S | -117.2 | 156.4 | 113.0 | 0.595 | 0.137 |
A:P01375:0.137 |
||||||||||||
GLU | C:148 | C:146 | 155.0 | 0.816 | S | 62.7 | 113.9 | NA | NA | NA | |||||||||||||
GLU | D:148 | D:146 | 135.0 | 0.711 | S | -136.3 | 165.6 | NA | NA | NA | |||||||||||||
GLU | E:148 | F:146 | 97.0 | 0.511 | T | -73.6 | 73.7 | NA | NA | NA | |||||||||||||
GLU | F:148 | G:146 | 139.0 | 0.732 | S | -115.3 | 146.7 | NA | NA | NA | |||||||||||||
GLU | G:148 | H:146 | 139.0 | 0.732 | S | -103.3 | 123.3 | NA | NA | NA | |||||||||||||
GLU | H:148 | I:146 | 139.0 | 0.732 | S | -134.2 | 168.2 | NA | NA | NA | |||||||||||||
GLU | I:148 | J:146 | 112.0 | 0.589 | S | -73.8 | 73.1 | NA | NA | NA | |||||||||||||
GLU | J:148 | K:146 | 134.0 | 0.705 | S | -121.3 | 160.1 | NA | NA | NA | |||||||||||||
GLU | K:148 | L:146 | 100.0 | 0.526 | S | -93.9 | 133.5 | NA | NA | NA | |||||||||||||
GLU | L:148 | M:146 | 126.0 | 0.663 | S | -115.8 | 159.2 | NA | NA | NA | |||||||||||||
GLU | M:148 | N:146 | 79.0 | 0.416 | T | -78.1 | 77.6 | NA | NA | NA | |||||||||||||
GLU | N:148 | O:146 | 135.0 | 0.711 | S | -132.3 | 162.0 | NA | NA | NA | |||||||||||||
GLU | O:148 | P:146 | 149.0 | 0.784 | S | 64.5 | 79.9 | NA | NA | NA | |||||||||||||
GLU | P:148 | Q:146 | 139.0 | 0.732 | S | -95.4 | 175.2 | NA | NA | NA | |||||||||||||
GLU | Q:148 | R:146 | 94.0 | 0.495 | T | -77.7 | 68.3 | NA | NA | NA | |||||||||||||
GLU | R:148 | S:146 | 142.0 | 0.747 | S | -139.5 | 152.5 | NA | NA | NA | |||||||||||||
GLU | S:148 | T:146 | 117.0 | 0.616 | S | -92.9 | 108.3 | NA | NA | NA | |||||||||||||
GLU | T:148 | U:146 | 143.0 | 0.753 | S | -122.2 | 159.6 | NA | NA | NA | |||||||||||||
GLU | U:148 | V:146 | 84.0 | 0.442 | T | -128.7 | 43.6 | NA | NA | NA | |||||||||||||
GLU | V:148 | W:146 | 137.0 | 0.721 | S | -138.9 | 148.0 | NA | NA | NA | |||||||||||||
GLU | W:148 | X:146 | 99.0 | 0.521 | S | -107.5 | 122.4 | NA | NA | NA | |||||||||||||
GLU | X:148 | Y:146 | 132.0 | 0.695 | S | -143.5 | 165.9 | NA | NA | NA | |||||||||||||
GLU | Y:148 | Z:146 | 117.0 | 0.616 | S | -107.5 | 147.5 | NA | NA | NA | |||||||||||||
GLU | Z:148 | a:146 | 137.0 | 0.721 | S | -92.7 | -176.1 | NA | NA | NA | |||||||||||||
GLU | AA:148 | b:146 | 108.0 | 0.568 | S | -79.7 | 129.5 | NA | NA | NA | |||||||||||||
GLU | BA:148 | c:146 | 129.0 | 0.679 | S | -106.2 | 152.3 | NA | NA | NA | |||||||||||||
GLU | CA:148 | d:146 | 111.0 | 0.584 | T | -83.2 | 80.8 | NA | NA | NA | |||||||||||||
GLU | DA:148 | e:146 | 149.0 | 0.784 | S | -87.6 | 142.7 | NA | NA | NA | |||||||||||||
GLU | EA:148 | f:146 | 154.0 | 0.811 | S | -90.2 | 119.3 | NA | NA | NA | |||||||||||||
GLU | FA:148 | g:146 | 132.0 | 0.695 | S | -79.2 | 165.6 | NA | NA | NA | |||||||||||||
GLU | GA:148 | h:146 | 93.0 | 0.489 | T | -80.7 | 84.5 | NA | NA | NA | |||||||||||||
GLU | HA:148 | i:146 | 132.0 | 0.695 | S | -106.5 | 173.7 | NA | NA | NA | |||||||||||||
GLU | IA:148 | j:146 | 96.0 | 0.505 | S | -104.5 | 129.1 | NA | NA | NA | |||||||||||||
GLU | JA:148 | k:146 | 129.0 | 0.679 | S | -112.6 | 147.4 | NA | NA | NA | |||||||||||||
GLU | KA:148 | l:146 | 75.0 | 0.395 | S | -67.1 | 79.9 | NA | NA | NA | |||||||||||||
GLU | LA:148 | m:146 | 138.0 | 0.726 | S | -124.4 | 145.8 | NA | NA | NA | |||||||||||||
GLU | MA:148 | n:146 | 118.0 | 0.621 | S | -87.4 | 91.3 | NA | NA | NA | |||||||||||||
GLU | NA:148 | o:146 | 136.0 | 0.716 | S | -123.5 | 153.2 | NA | NA | NA | |||||||||||||
GLU | OA:148 | p:146 | 92.0 | 0.484 | T | -67.8 | 79.8 | NA | NA | NA | |||||||||||||
GLU | PA:148 | q:146 | 140.0 | 0.737 | S | -117.8 | 156.7 | NA | NA | NA | |||||||||||||
GLU | QA:148 | r:146 | 128.0 | 0.674 | S | 67.1 | -71.7 | NA | NA | NA | |||||||||||||
GLU | RA:148 | s:146 | 125.0 | 0.658 | S | -117.5 | 159.0 | NA | NA | NA | |||||||||||||
GLU | SA:148 | t:146 | 75.0 | 0.395 | T | -140.4 | 73.9 | NA | NA | NA | |||||||||||||
GLU | TA:148 | u:146 | 141.0 | 0.742 | S | -96.7 | 142.9 | NA | NA | NA | |||||||||||||
GLU | UA:148 | v:146 | 143.0 | 0.753 | S | 61.4 | 93.2 | NA | NA | NA | |||||||||||||
GLU | VA:148 | w:146 | 148.0 | 0.779 | S | -139.4 | 178.3 | NA | NA | NA | |||||||||||||
6x81 | 1 | P01375 | 100.0 | 9e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 139.0 | 0.732 | S | -124.8 | 165.0 | 104.0 | 0.547 | 0.185 |
C:P01375:0.184 |
HOH |
2.704 |
OE1 |
O |
|
GLU | B:147 | B:146 | 192.0 | 1.0 | T | -75.9 | 14.3 | 104.0 | 0.547 | 0.453 |
A:P01375:0.463 |
HOH |
2.710 |
OE2 |
O |
||||||||
GLU | C:147 | C:146 | 148.0 | 0.779 | S | -103.7 | -170.6 | 115.0 | 0.605 | 0.174 |
B:P01375:0.174 |
HOH |
2.714 |
OE1 |
O |
||||||||
GLU | D:147 | D:146 | 132.0 | 0.695 | S | -168.1 | 155.7 | NA | NA | NA | |||||||||||||
GLU | E:147 | E:146 | 186.0 | 0.979 | T | -72.3 | -6.9 | NA | NA | NA | |||||||||||||
GLU | F:147 | F:146 | 142.0 | 0.747 | S | -140.8 | 163.7 | NA | NA | NA | |||||||||||||
6x82 | 1 | P01375 | 100.0 | 9e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 125.0 | 0.658 | S | -108.2 | 142.5 | 103.0 | 0.542 | 0.116 |
C:P01375:0.116 |
|||||
GLU | B:147 | B:146 | 194.0 | 1.0 | T | -78.2 | 4.0 | 95.0 | 0.5 | 0.5 |
A:P01375:0.521 |
HOH |
3.662 |
OE1 |
O |
||||||||
GLU | C:147 | C:146 | 135.0 | 0.711 | S | -127.6 | 161.8 | 125.0 | 0.658 | 0.053 |
B:P01375:0.053 |
HOH |
2.991 |
O |
O |
||||||||
GLU | D:147 | D:146 | 101.0 | 0.532 | S | -113.7 | 177.4 | NA | NA | NA | |||||||||||||
GLU | E:147 | E:146 | 191.0 | 1.0 | T | -65.6 | -7.6 | NA | NA | NA | |||||||||||||
GLU | F:147 | F:146 | 144.0 | 0.758 | S | -136.2 | 163.7 | NA | NA | NA | |||||||||||||
6x83 | 1 | P01375 | 100.0 | 9e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 156.0 | 0.821 | S | -112.6 | 177.3 | 126.0 | 0.663 | 0.158 |
C:P01375:0.158 |
HOH |
8.575 |
O |
O |
|
GLU | B:147 | B:146 | 103.0 | 0.542 | S | -86.0 | -27.7 | 58.0 | 0.305 | 0.237 |
A:P01375:0.237 |
HOH |
2.750 |
OE2 |
O |
||||||||
GLU | C:147 | C:146 | 128.0 | 0.674 | S | -121.4 | 150.3 | 110.0 | 0.579 | 0.095 |
B:P01375:0.095 |
HOH |
5.505 |
O |
O |
||||||||
GLU | D:147 | D:146 | 153.0 | 0.805 | S | -97.2 | -121.2 | NA | NA | NA | |||||||||||||
GLU | E:147 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
GLU | F:147 | F:146 | 154.0 | 0.811 | S | -69.4 | 164.1 | NA | NA | NA | |||||||||||||
6x85 | 1 | P01375 | 100.0 | 9e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 141.0 | 0.742 | S | -141.4 | 170.3 | 112.0 | 0.589 | 0.153 |
C:P01375:0.153 |
|||||
GLU | B:147 | B:146 | 80.0 | 0.421 | -140.3 | 139.0 | 79.0 | 0.416 | 0.005 |
A:P01375:0.005 |
|||||||||||||
GLU | C:147 | C:146 | 143.0 | 0.753 | S | -99.9 | 161.5 | 111.0 | 0.584 | 0.169 |
B:P01375:0.168 |
||||||||||||
GLU | D:147 | D:146 | 126.0 | 0.663 | S | -143.6 | 135.2 | NA | NA | NA | |||||||||||||
GLU | E:147 | E:146 | 129.0 | 0.679 | S | -87.8 | 151.5 | NA | NA | NA | |||||||||||||
GLU | F:147 | F:146 | 131.0 | 0.689 | S | -100.9 | 154.1 | NA | NA | NA | |||||||||||||
6x86 | 1 | P01375 | 100.0 | 9e-115 |
X-RAY |
2021-01-13 | GLU | A:147 | A:146 | 140.0 | 0.737 | S | -130.8 | 161.2 | 108.0 | 0.568 | 0.169 |
C:P01375:0.168 |
HOH |
9.776 |
O |
O |
|
GLU | B:147 | B:146 | 134.0 | 0.705 | S | -107.2 | 17.0 | 81.0 | 0.426 | 0.279 |
A:P01375:0.279 |
HOH |
7.648 |
O |
O |
||||||||
GLU | C:147 | C:146 | 144.0 | 0.758 | S | -109.3 | 156.9 | 113.0 | 0.595 | 0.163 |
B:P01375:0.163 |
HOH |
3.098 |
CA |
O |
||||||||
GLU | D:147 | D:146 | 151.0 | 0.795 | S | -137.8 | 168.4 | NA | NA | NA | |||||||||||||
GLU | E:147 | E:146 | 162.0 | 0.853 | S | 65.4 | -7.4 | NA | NA | NA | |||||||||||||
GLU | F:147 | F:146 | 147.0 | 0.774 | S | -116.4 | 151.2 | NA | NA | NA | |||||||||||||
5yoy | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2018-05-09 | GLU | A:154 | A:146 | 131.0 | 0.689 | S | -124.0 | 170.0 | 117.0 | 0.616 | 0.073 |
C:P01375:0.074 |
|||||
GLU | B:154 | B:146 | 129.0 | 0.679 | S | -110.3 | 176.5 | 114.0 | 0.6 | 0.079 |
A:P01375:0.079 |
||||||||||||
GLU | C:154 | C:146 | 133.0 | 0.7 | S | -119.9 | 164.8 | 93.0 | 0.489 | 0.211 |
B:P01375:0.211 |
HOH |
4.883 |
O |
O |
||||||||
GLU | J:154 | J:146 | 131.0 | 0.689 | S | -116.7 | 164.2 | NA | NA | NA | |||||||||||||
GLU | K:154 | K:146 | 130.0 | 0.684 | S | -114.6 | 171.5 | NA | NA | NA | |||||||||||||
GLU | L:154 | L:146 | 127.0 | 0.668 | S | -121.8 | 166.6 | NA | NA | NA | |||||||||||||
7jra | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2020-12-09 | GLU | A:149 | A:222 | 56.0 | NA | S | -77.2 | 148.1 | 45.0 | NA | NA |
B:P01375:NA |
HOH |
2.960 |
O |
O |
|
GLU | B:149 | B:222 | 54.0 | NA | S | -122.3 | 165.8 | 35.0 | NA | NA |
C:P01375:NA |
HOH |
2.740 |
O |
O |
||||||||
GLU | C:149 | C:222 | 86.0 | NA | -67.5 | 48.9 | 86.0 | NA | NA |
HOH |
5.770 |
C |
O |
||||||||||
4g3y | 3 | P01375 | 100.0 | 1e-114 |
X-RAY |
2013-03-27 | GLU | C:146 | C:146 | 131.0 | 0.689 | S | -137.5 | 158.7 | 120.0 | 0.632 | 0.057 |
A:None:0.032 C:P01375:0.026 |
HOH |
2.757 |
OE2 |
O |
|
4twt | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2015-02-04 | GLU | A:146 | A:146 | 126.0 | 0.663 | S | -137.5 | 154.8 | 115.0 | 0.605 | 0.058 |
B:P01375:0.058 |
HOH |
4.784 |
O |
O |
|
GLU | B:146 | B:146 | 108.0 | 0.568 | S | -95.3 | 112.8 | 108.0 | 0.568 | 0.0 |
HOH |
4.746 |
O |
O |
|||||||||
GLU | E:146 | C:146 | 131.0 | 0.689 | S | -135.3 | 152.6 | NA | NA | NA | |||||||||||||
GLU | F:146 | D:146 | 98.0 | 0.516 | S | -122.1 | 138.6 | NA | NA | NA | |||||||||||||
5m2i | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2017-08-30 | GLU | A:146 | A:146 | 139.0 | 0.732 | S | -128.1 | 151.5 | 8.0 | 0.042 | 0.69 |
C:P01375:0.089 I:None:0.663 |
HOH |
2.729 |
O |
O |
|
GLU | B:146 | B:146 | 137.0 | 0.721 | S | -128.1 | 152.0 | 9.0 | 0.047 | 0.674 |
A:P01375:0.1 H:None:0.637 |
HOH |
3.262 |
OE2 |
O |
||||||||
GLU | C:146 | C:146 | 133.0 | 0.7 | S | -129.7 | 150.7 | 5.0 | 0.026 | 0.674 |
G:None:0.647 B:P01375:0.095 |
HOH |
2.907 |
O |
O |
||||||||
GLU | D:146 | D:146 | 139.0 | 0.732 | S | -128.8 | 153.2 | NA | NA | NA | |||||||||||||
GLU | E:146 | E:146 | 141.0 | 0.742 | S | -129.2 | 152.1 | NA | NA | NA | |||||||||||||
GLU | F:146 | F:146 | 133.0 | 0.7 | S | -130.2 | 150.6 | NA | NA | NA | |||||||||||||
5m2j | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2017-08-30 | GLU | A:146 | A:146 | 119.0 | 0.626 | S | -80.4 | 127.2 | 110.0 | 0.579 | 0.047 |
A:P01375:0.047 |
HOH |
2.704 |
OE1 |
O |
|
5m2m | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2017-08-30 | GLU | A:146 | A:146 | 139.0 | 0.732 | S | -125.6 | 156.6 | 126.0 | 0.663 | 0.069 |
F:None:0.063 C:P01375:0.005 |
HOH |
2.691 |
O |
O |
|
GLU | B:146 | B:146 | 135.0 | 0.711 | S | -126.7 | 156.1 | 121.0 | 0.637 | 0.074 |
D:None:0.068 A:P01375:0.005 |
HOH |
2.792 |
O |
O |
||||||||
GLU | C:146 | C:146 | 136.0 | 0.716 | S | -124.9 | 156.9 | 123.0 | 0.647 | 0.069 |
E:None:0.068 |
HOH |
2.819 |
O |
O |
||||||||
GLU | G:146 | G:146 | 137.0 | 0.721 | S | -126.2 | 158.2 | NA | NA | NA | |||||||||||||
GLU | I:146 | I:146 | 138.0 | 0.726 | S | -125.2 | 158.8 | NA | NA | NA | |||||||||||||
GLU | K:146 | M:146 | 136.0 | 0.716 | S | -124.7 | 157.5 | NA | NA | NA | |||||||||||||
5wux | 3 | C1K3N5 | 100.0 | 1e-114 |
X-RAY |
2017-06-07 | GLU | G:146 | E:146 | 118.0 | 0.621 | S | -96.7 | 179.3 | NA | NA | NA | ||||||
GLU | H:146 | F:146 | 137.0 | 0.721 | S | -85.1 | -174.6 | 137.0 | 0.721 | 0.0 | |||||||||||||
GLU | I:146 | G:146 | 168.0 | 0.884 | S | -113.9 | 155.9 | NA | NA | NA | |||||||||||||
6ooy | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2019-12-25 | GLU | A:146 | A:146 | 140.0 | 0.737 | S | -150.3 | 156.2 | 113.0 | 0.595 | 0.142 |
B:P01375:0.142 |
HOH |
2.761 |
O |
O |
|
GLU | B:146 | B:146 | 147.0 | 0.774 | S | -116.3 | 171.0 | 79.0 | 0.416 | 0.358 |
C:P01375:0.358 |
HOH |
2.416 |
OE2 |
O |
||||||||
GLU | C:146 | C:146 | 69.0 | NA | S | -163.7 | -144.6 | 69.0 | NA | NA |
HOH |
8.534 |
CB |
O |
|||||||||
6ooz | 1 | P01375 | 100.0 | 1e-114 |
X-RAY |
2019-12-25 | GLU | A:146 | A:146 | 171.0 | 0.9 | S | 70.0 | 151.0 | 138.0 | 0.726 | 0.174 |
B:P01375:0.174 |
HOH |
2.480 |
OE2 |
O |
|
GLU | B:146 | B:146 | 149.0 | 0.784 | S | -122.0 | 173.2 | 94.0 | 0.495 | 0.289 |
C:P01375:0.289 |
CL HOH |
5.317 2.885 |
OE2 O |
CL O |
||||||||
GLU | C:146 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6rmj | 1 | P01375 | 99.37 | 3e-114 |
X-RAY |
2019-10-09 | GLU | A:152 | A:146 | 138.0 | 0.726 | S | -110.9 | 133.1 | 99.0 | 0.521 | 0.205 |
C:P01375:0.205 |
HOH |
4.197 |
C |
O |
|
GLU | B:152 | B:146 | 129.0 | 0.679 | S | -112.1 | 115.6 | 64.0 | 0.337 | 0.342 |
A:P01375:0.342 |
HOH |
7.670 |
OE2 |
O |
||||||||
GLU | C:152 | C:146 | 114.0 | 0.6 | S | -100.5 | 73.7 | 64.0 | 0.337 | 0.263 |
B:P01375:0.263 |
HOH |
2.718 |
O |
O |
||||||||
5uui | 1 | P01375 | 98.73 | 1e-113 |
X-RAY |
2017-08-02 | GLU | A:147 | A:146 | 53.0 | NA | S | -142.3 | 158.3 | 47.0 | NA | NA |
A:P01375:NA |
MTN HOH |
6.518 2.915 |
CB O |
O1 O |
|
1a8m | 1 | P01375 | 99.36 | 1e-113 |
X-RAY |
1998-06-17 | GLU | A:146 | A:146 | 94.0 | 0.495 | -124.2 | 158.2 | 53.0 | 0.279 | 0.216 |
C:P01375:0.216 |
HOH |
3.632 |
N |
O |
||
GLU | B:146 | B:146 | 24.0 | 0.126 | -74.5 | -95.8 | 11.0 | 0.058 | 0.068 |
A:P01375:0.068 |
HOH |
5.045 |
N |
O |
|||||||||
GLU | C:146 | C:146 | 16.0 | 0.084 | 19.4 | 92.3 | 16.0 | 0.084 | 0.0 |
HOH |
5.586 |
C |
O |
||||||||||
3wd5 | 1 | P01375 | 99.36 | 1e-113 |
X-RAY |
2013-08-14 | GLU | A:146 | A:146 | 131.0 | 0.689 | S | -143.3 | 165.3 | 36.0 | 0.189 | 0.5 |
C:None:0.5 |
HOH |
4.231 |
N |
O |
|
1tnf | 1 | P01375 | 99.36 | 5e-113 |
X-RAY |
1990-01-15 | GLU | A:146 | A:146 | 92.0 | 0.484 | -144.8 | 131.0 | 50.0 | 0.263 | 0.221 |
C:P01375:0.221 |
||||||
GLU | B:146 | B:146 | 11.0 | 0.058 | -102.4 | 143.9 | 11.0 | 0.058 | 0.0 | ||||||||||||||
GLU | C:146 | C:146 | 27.0 | 0.142 | -78.7 | 127.9 | 27.0 | 0.142 | 0.0 | ||||||||||||||
2tun | 1 | P01375 | 98.73 | 2e-112 |
X-RAY |
1994-01-31 | GLU | A:146 | A:146 | 96.0 | 0.505 | S | -100.7 | 164.7 | 44.0 | 0.232 | 0.273 |
C:P01375:0.274 |
|||||
GLU | B:146 | B:146 | 48.0 | 0.253 | S | -121.7 | -152.1 | 45.0 | 0.237 | 0.016 |
A:P01375:0.016 |
||||||||||||
GLU | C:146 | C:146 | 30.0 | 0.158 | -132.4 | -172.0 | 30.0 | 0.158 | 0.0 | ||||||||||||||
GLU | D:146 | D:146 | 90.0 | 0.474 | -127.2 | 131.4 | 51.0 | 0.268 | 0.206 |
F:P01375:0.205 |
|||||||||||||
GLU | E:146 | E:146 | 52.0 | 0.274 | S | -161.4 | -166.4 | 47.0 | 0.247 | 0.027 |
D:P01375:0.026 |
||||||||||||
GLU | F:146 | F:146 | 25.0 | 0.132 | -69.4 | 76.7 | 25.0 | 0.132 | 0.0 | ||||||||||||||
3it8 | 1 | P01375 | 99.34 | 1e-109 |
X-RAY |
2009-10-20 | GLU | A:150 | A:146 | 119.0 | 0.626 | S | -71.8 | -81.7 | 65.0 | 0.342 | 0.284 |
B:P01375:0.284 |
HOH |
7.102 |
OE2 |
O |
|
GLU | B:150 | B:146 | 121.0 | 0.637 | S | -71.5 | -81.8 | 64.0 | 0.337 | 0.3 |
C:P01375:0.3 |
HOH |
7.517 |
OE2 |
O |
||||||||
GLU | C:150 | C:146 | 121.0 | 0.637 | S | -70.8 | -83.2 | 66.0 | 0.347 | 0.29 |
A:P01375:0.289 |
HOH |
6.839 |
OE2 |
O |
||||||||
GLU | G:150 | G:146 | 121.0 | 0.637 | S | -71.7 | -82.2 | NA | NA | NA | |||||||||||||
GLU | H:150 | H:146 | 122.0 | 0.642 | S | -70.6 | -82.9 | NA | NA | NA | |||||||||||||
GLU | I:150 | I:146 | 121.0 | 0.637 | S | -70.9 | -83.3 | NA | NA | NA | |||||||||||||
3alq | 1 | P01375 | 96.18 | 2e-109 |
X-RAY |
2010-11-17 | GLU | A:146 | A:146 | 148.0 | 0.779 | S | -117.1 | 171.2 | 37.0 | 0.195 | 0.584 |
B:P01375:0.205 G:P20333:0.432 |
|||||
GLU | B:146 | B:146 | 150.0 | 0.789 | S | -103.2 | 170.3 | 35.0 | 0.184 | 0.605 |
C:P01375:0.232 H:P20333:0.447 |
||||||||||||
GLU | C:146 | C:146 | 141.0 | 0.742 | S | -119.0 | 163.1 | 32.0 | 0.168 | 0.574 |
I:P20333:0.437 A:P01375:0.195 |
HOH |
4.785 |
OE1 |
O |
||||||||
GLU | D:146 | D:146 | 141.0 | 0.742 | S | -96.7 | 164.9 | NA | NA | NA | |||||||||||||
GLU | E:146 | E:146 | 141.0 | 0.742 | S | -120.8 | 168.8 | NA | NA | NA | |||||||||||||
GLU | F:146 | F:146 | 141.0 | 0.742 | S | -122.7 | 173.9 | NA | NA | NA | |||||||||||||
3l9j | 2 | P01375 | 100.0 | 1e-108 |
X-RAY |
2010-02-23 | GLU | B:138 | T:146 | 134.0 | 0.705 | S | -85.8 | 149.4 | 134.0 | 0.705 | 0.0 |
HOH |
2.647 |
OE1 |
O |
||
2az5 | 1 | P01375 | 100.0 | 6e-108 |
X-RAY |
2005-11-29 | GLU | A:137 | A:146 | 48.0 | NA | S | -99.7 | 118.7 | 48.0 | NA | NA |
HOH |
7.520 |
C |
O |
||
GLU | B:137 | B:146 | 50.0 | NA | S | -103.8 | 153.5 | 37.0 | NA | NA |
A:P01375:NA |
HOH |
3.021 |
O |
O |
||||||||
GLU | C:137 | C:146 | 122.0 | 0.642 | S | -94.9 | 127.7 | 122.0 | 0.642 | 0.0 |
HOH |
2.762 |
N |
O |
|||||||||
GLU | D:137 | D:146 | 135.0 | 0.711 | S | -113.4 | 152.8 | 113.0 | 0.595 | 0.116 |
C:P01375:0.116 |
HOH |
2.892 |
O |
O |
||||||||
4tsv | 1 | P01375 | 98.0 | 6e-107 |
X-RAY |
1998-12-30 | GLU | A:139 | A:146 | 53.0 | NA | S | -171.0 | 170.8 | 53.0 | NA | NA |
HOH |
2.822 |
O |
O |
||
5tsw | 1 | P01375 | 98.0 | 6e-107 |
X-RAY |
1999-05-07 | GLU | A:139 | A:146 | 117.0 | 0.616 | S | -161.0 | -177.5 | 111.0 | 0.584 | 0.032 |
C:P01375:0.032 |
HOH |
2.848 |
CA |
H2 |
|
GLU | B:139 | B:146 | 50.0 | NA | S | -116.3 | 166.2 | 44.0 | NA | NA |
A:P01375:NA |
HOH |
2.415 |
O |
H2 |
||||||||
GLU | C:139 | C:146 | 138.0 | 0.726 | S | -125.8 | 162.4 | 128.0 | 0.674 | 0.052 |
B:P01375:0.053 |
HOH |
2.199 |
O |
H1 |
||||||||
GLU | D:139 | D:146 | 49.0 | NA | S | -118.3 | 165.2 | NA | NA | NA | |||||||||||||
GLU | E:139 | E:146 | 50.0 | NA | S | -124.5 | 158.4 | NA | NA | NA | |||||||||||||
GLU | F:139 | F:146 | 41.0 | NA | S | -160.0 | -173.8 | NA | NA | NA | |||||||||||||
2e7a | 1 | P01375 | 92.36 | 9e-106 |
X-RAY |
2007-11-13 | GLU | A:146 | A:146 | 136.0 | 0.716 | S | -134.1 | 156.7 | 127.0 | 0.668 | 0.048 |
B:P01375:0.047 |
HOH |
2.604 |
OE2 |
O |
|
GLU | B:146 | B:146 | 132.0 | 0.695 | S | -133.7 | 153.5 | 129.0 | 0.679 | 0.016 |
C:P01375:0.016 |
HOH |
2.741 |
O |
O |
||||||||
GLU | C:146 | C:146 | 134.0 | 0.705 | S | -132.7 | 154.4 | 123.0 | 0.647 | 0.058 |
A:P01375:0.058 |
HOH |
2.605 |
OE1 |
O |
||||||||
2zjc | 1 | P01375 | 92.99 | 3e-105 |
X-RAY |
2009-01-20 | SER | A:146 | A:146 | 66.0 | 0.574 | S | -149.4 | 155.6 | 50.0 | 0.435 | 0.139 |
C:P01375:0.139 |
HOH |
2.862 |
O |
O |
|
SER | B:146 | B:146 | 66.0 | 0.574 | S | -45.2 | 133.3 | 66.0 | 0.574 | 0.0 |
HOH |
4.020 |
OG |
O |
|||||||||
SER | C:146 | C:146 | 78.0 | 0.678 | S | -130.1 | 164.7 | 53.0 | 0.461 | 0.217 |
B:P01375:0.217 |
HOH |
4.742 |
OG |
O |
||||||||
2zpx | 1 | P01375 | 92.36 | 3e-104 |
X-RAY |
2009-03-24 | GLU | A:146 | A:146 | 135.0 | 0.711 | S | -104.7 | 163.1 | 123.0 | 0.647 | 0.064 |
C:P01375:0.063 |
|||||
GLU | B:146 | B:146 | 143.0 | 0.753 | S | -110.3 | 170.5 | 111.0 | 0.584 | 0.169 |
A:P01375:0.168 |
||||||||||||
GLU | C:146 | C:146 | 131.0 | 0.689 | S | -178.4 | 152.9 | 79.0 | 0.416 | 0.273 |
B:P01375:0.274 |
||||||||||||
7kp7 | 1 | P06804 | 80.54 | 4e-88 |
X-RAY |
2021-01-13 | GLU | A:137 | B:146 | 128.0 | 0.674 | S | -138.6 | 166.0 | 45.0 | 0.237 | 0.437 |
C:P06804:0.068 E:P19438:0.374 |
HOH |
4.667 |
OE1 |
O |
|
GLU | B:137 | A:146 | 129.0 | 0.679 | S | -140.1 | 163.5 | 45.0 | 0.237 | 0.442 |
A:P06804:0.068 D:P19438:0.374 |
SO4 HOH |
7.991 2.616 |
OE2 OE1 |
O4 O |
||||||||
GLU | C:137 | C:146 | 128.0 | 0.674 | S | -139.2 | 164.1 | 44.0 | 0.232 | 0.442 |
F:P19438:0.368 B:P06804:0.074 |
SO4 HOH |
9.139 2.695 |
OE1 OE2 |
O2 O |
||||||||
7kp8 | 1 | P06804 | 80.41 | 1e-87 |
X-RAY |
2021-01-13 | GLU | A:136 | A:145 | 129.0 | 0.679 | S | -125.0 | 166.3 | 37.0 | 0.195 | 0.484 |
D:P19438:0.416 B:P06804:0.068 |
|||||
GLU | B:136 | B:145 | 134.0 | 0.705 | S | -123.7 | 166.2 | 34.0 | 0.179 | 0.526 |
C:P06804:0.074 E:P19438:0.458 |
HOH |
3.787 |
OE1 |
O |
||||||||
GLU | C:136 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p01375-f1 | 1 | P01375 | 100.0 | 2e-174 | GLU | A:222 | A:222 | 137.0 | 0.721 | S | -124.4 | 149.4 |