Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr6 | 31918084 | . | A | C | CCDS4729.1:NM_001710.5:c.1528Agc>Cgc_NP_001701.2:p.510S>R | Homo sapiens complement factor B (CFB), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7jtn | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2020-12-09 | SER | A:510 | A:485 | 46.0 | 0.4 | E | -118.0 | 123.2 | 46.0 | 0.4 | 0.0 | ||||||
| SER | C:510 | C:485 | 48.0 | 0.417 | E | -118.0 | 123.1 | NA | NA | NA | |||||||||||||
| 7jtq | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2020-12-09 | SER | A:510 | A:485 | 40.0 | 0.348 | E | -87.7 | 97.5 | 40.0 | 0.348 | 0.0 | ||||||
| SER | C:510 | C:485 | 41.0 | 0.357 | E | -88.2 | 97.5 | NA | NA | NA | |||||||||||||
| 2ok5 | 1 | P00751 | 99.86 | 0.0 |
X-RAY |
2007-02-27 | SER | A:495 | A:485 | 36.0 | 0.313 | E | -130.0 | 119.4 | 36.0 | 0.313 | 0.0 |
HOH |
2.968 |
OG |
O |
||
| 2xwj | 3 | P00751 | 99.73 | 0.0 |
X-RAY |
2011-01-12 | SER | I:485 | I:485 | 25.0 | 0.217 | E | -105.2 | 103.6 | 25.0 | 0.217 | 0.0 | ||||||
| SER | J:485 | J:485 | 22.0 | 0.191 | E | -109.3 | 103.3 | NA | NA | NA | |||||||||||||
| SER | K:485 | K:485 | 22.0 | 0.191 | E | -104.4 | 103.2 | NA | NA | NA | |||||||||||||
| SER | L:485 | L:485 | 20.0 | 0.174 | E | -107.3 | 103.1 | NA | NA | NA | |||||||||||||
| 3hrz | 4 | P00751 | 99.73 | 0.0 |
X-RAY |
2009-07-07 | SER | D:485 | D:485 | 105.0 | 0.913 | 360.0 | 111.3 | 105.0 | 0.913 | 0.0 |
HOH |
3.416 |
C |
O |
|||
| 3hs0 | 4 | P00751 | 99.73 | 0.0 |
X-RAY |
2009-07-07 | SER | D:485 | D:485 | 109.0 | 0.948 | 360.0 | 124.9 | NA | NA | NA | |||||||
| SER | H:485 | I:485 | 70.0 | 0.609 | -133.1 | 88.6 | 70.0 | 0.609 | 0.0 | ||||||||||||||
| 2xwb | 3 | P00751 | 99.73 | 0.0 |
X-RAY |
2011-01-12 | SER | E:476 | F:485 | 21.0 | 0.183 | E | -113.5 | 105.7 | 21.0 | 0.183 | 0.0 | ||||||
| SER | F:476 | H:485 | 31.0 | 0.27 | E | -114.0 | 106.6 | NA | NA | NA | |||||||||||||
| 2win | 3 | P00751 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | SER | I:251 | I:485 | 39.0 | 0.339 | E | -105.2 | 122.0 | NA | NA | NA | ||||||
| SER | J:251 | J:485 | 39.0 | 0.339 | E | -105.1 | 122.1 | 39.0 | 0.339 | 0.0 | |||||||||||||
| SER | K:251 | K:485 | 37.0 | 0.322 | E | -105.2 | 122.0 | NA | NA | NA | |||||||||||||
| SER | L:251 | L:485 | 37.0 | 0.322 | E | -105.2 | 122.0 | 37.0 | 0.322 | 0.0 | |||||||||||||
| 6rur | 5 | P00751 | 99.6 | 0.0 |
X-RAY |
2019-08-21 | SER | I:251 | J:485 | 24.0 | 0.209 | E | -134.4 | 137.1 | 24.0 | 0.209 | 0.0 | ||||||
| SER | J:251 | L:485 | 24.0 | 0.209 | E | -131.5 | 136.8 | 24.0 | 0.209 | 0.0 | |||||||||||||
| 6ruv | 6 | P00751 | 99.6 | 0.0 |
X-RAY |
2019-08-21 | SER | K:251 | J:485 | 25.0 | 0.217 | E | -122.9 | 135.9 | 25.0 | 0.217 | 0.0 | ||||||
| SER | L:251 | L:485 | 26.0 | 0.226 | E | -122.9 | 137.1 | 26.0 | 0.226 | 0.0 | |||||||||||||
| 1rrk | 1 | P00751 | 99.4 | 0.0 |
X-RAY |
2004-12-14 | SER | A:243 | A:485 | 48.0 | 0.417 | E | -134.6 | 118.5 | 48.0 | 0.417 | 0.0 |
HOH |
2.577 |
O |
O |
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| 1rs0 | 1 | P00751 | 99.4 | 0.0 |
X-RAY |
2004-12-14 | SER | A:243 | A:485 | 51.0 | 0.443 | E | -131.9 | 131.2 | 51.0 | 0.443 | 0.0 |
DFP HOH |
4.132 7.150 |
O N |
C2 O |
||
| 1rtk | 1 | P00751 | 99.4 | 0.0 |
X-RAY |
2004-12-14 | SER | A:243 | A:485 | 46.0 | 0.4 | E | -140.0 | 124.6 | 46.0 | 0.4 | 0.0 |
GBS HOH |
6.356 2.709 |
O O |
OD O |
||
| 1dle | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2000-12-13 | SER | A:44 | A:41 | 48.0 | 0.417 | E | -130.3 | 125.6 | 46.0 | 0.4 | 0.017 |
B:P00751:0.017 |
HOH |
2.724 |
N |
O |
|
| SER | B:44 | B:41 | 57.0 | 0.496 | E | -130.8 | 125.9 | 55.0 | 0.478 | 0.018 |
A:P00751:0.017 |
HOH |
2.773 |
OG |
O |
||||||||
| 6qsw | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2019-03-27 | SER | A:37 | AAA:41 | 58.0 | 0.504 | E | -116.0 | 144.7 | 58.0 | 0.504 | 0.0 |
JGT HOH |
8.325 2.348 |
O H |
C15 O |
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| SER | B:37 | BBB:41 | 64.0 | 0.557 | E | -115.8 | 148.6 | NA | NA | NA | |||||||||||||
| SER | C:37 | CCC:41 | 50.0 | 0.435 | E | -116.6 | 143.8 | NA | NA | NA | |||||||||||||
| 6qsx | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2019-03-27 | SER | A:37 | AAA:41 | 24.0 | 0.209 | E | -153.7 | 153.5 | 24.0 | 0.209 | 0.0 |
JGN HOH |
8.012 2.579 |
O H |
C11 O |
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| SER | B:37 | BBB:41 | 36.0 | 0.313 | E | -153.5 | 151.8 | NA | NA | NA | |||||||||||||
| 6rav | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2019-04-17 | SER | A:37 | AAA:41 | 31.0 | 0.27 | E | -148.0 | 160.5 | 31.0 | 0.27 | 0.0 |
JGQ HOH |
8.099 2.447 |
O H |
C4 O |
||
| SER | B:37 | BBB:41 | 42.0 | 0.365 | E | -147.4 | 160.8 | NA | NA | NA | |||||||||||||
| 6t8u | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2020-03-04 | SER | A:37 | AAA:41 | 59.0 | 0.513 | E | -114.8 | 145.4 | 59.0 | 0.513 | 0.0 |
MVZ HOH |
8.071 5.363 |
O O |
C15 O |
||
| SER | B:37 | BBB:41 | 50.0 | 0.435 | E | -111.0 | 148.2 | NA | NA | NA | |||||||||||||
| SER | C:37 | CCC:41 | 51.0 | 0.443 | E | -114.2 | 143.9 | NA | NA | NA | |||||||||||||
| 6t8v | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2020-03-04 | SER | A:37 | AAA:41 | 32.0 | 0.278 | E | -159.9 | 165.9 | 32.0 | 0.278 | 0.0 |
MVK HOH |
8.041 2.662 |
O OG |
C7 O |
||
| SER | B:37 | BBB:41 | 33.0 | 0.287 | E | -152.7 | 151.1 | NA | NA | NA | |||||||||||||
| 6t8w | 1 | P00751 | 100.0 | 0.0 |
X-RAY |
2020-03-04 | SER | A:37 | AAA:41 | 31.0 | 0.27 | E | -153.6 | 165.1 | 31.0 | 0.27 | 0.0 |
MVW HOH |
8.071 2.722 |
O O |
C14 O |
||
| SER | B:37 | BBB:41 | 40.0 | 0.348 | E | -148.2 | 160.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00751-f1 | 1 | P00751 | 100.0 | 0.0 | SER | A:510 | A:510 | 54.0 | 0.47 | E | -116.8 | 125.3 | |