Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 31918407 . C A CCDS4729.1:NM_001710.5:c.1636Cgg>Agg_NP_001701.2:p.546R>R Homo sapiens complement factor B (CFB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7jtn 1 P00751 100.0 0.0 X-RAY
 2020-12-09 ARG A:546 A:521 130.0 0.578 -60.7 134.3 130.0 0.578 0.0
ARG C:546 C:521 129.0 0.573 -60.7 134.4 NA NA NA
7jtq 1 P00751 100.0 0.0 X-RAY
 2020-12-09 ARG A:546 A:521 122.0 0.542 -80.0 135.5 122.0 0.542 0.0
ARG C:546 C:521 125.0 0.556 -69.3 135.5 NA NA NA
2ok5 1 P00751 99.86 0.0 X-RAY
 2007-02-27 ARG A:531 A:521 170.0 0.756 -42.8 124.6 170.0 0.756 0.0 GOL
HOH
 3.993
2.539
 NE
O
 O1
O
2xwj 3 P00751 99.73 0.0 X-RAY
 2011-01-12 ARG I:521 I:521 162.0 0.72 S -75.7 168.8 162.0 0.72 0.0
ARG J:521 J:521 159.0 0.707 S -75.5 168.8 NA NA NA
ARG K:521 K:521 161.0 0.716 S -75.6 168.7 NA NA NA
ARG L:521 L:521 160.0 0.711 S -75.5 168.8 NA NA NA
3hrz 4 P00751 99.73 0.0 X-RAY
 2009-07-07 ARG D:521 D:521 189.0 0.84 -49.1 117.9 189.0 0.84 0.0 HOH
 8.066
 NH2
 O
3hs0 4 P00751 99.73 0.0 X-RAY
 2009-07-07 ARG D:521 D:521 149.0 0.662 -38.3 123.4 NA NA NA
ARG H:521 I:521 136.0 0.604 -44.4 120.7 136.0 0.604 0.0
2xwb 3 P00751 99.73 0.0 X-RAY
 2011-01-12 ARG E:512 F:521 154.0 0.684 S -70.6 166.9 154.0 0.684 0.0
ARG F:512 H:521 155.0 0.689 S -72.1 165.4 NA NA NA
2win 3 P00751 100.0 0.0 X-RAY
 2009-06-09 ARG I:287 I:521 179.0 0.796 -110.9 93.5 NA NA NA
ARG J:287 J:521 178.0 0.791 -110.9 93.4 178.0 0.791 0.0
ARG K:287 K:521 178.0 0.791 -110.9 93.5 NA NA NA
ARG L:287 L:521 179.0 0.796 -110.9 93.5 179.0 0.796 0.0
6rur 5 P00751 99.6 0.0 X-RAY
 2019-08-21 ARG I:287 J:521 181.0 0.804 S -74.7 122.2 181.0 0.804 0.0
ARG J:287 L:521 205.0 0.911 S -79.6 113.3 205.0 0.911 0.0
6ruv 6 P00751 99.6 0.0 X-RAY
 2019-08-21 ARG K:287 J:521 209.0 0.929 S -76.0 102.9 209.0 0.929 0.0
ARG L:287 L:521 205.0 0.911 S -75.7 102.8 205.0 0.911 0.0
1rrk 1 P00751 99.4 0.0 X-RAY
 2004-12-14 ARG A:279 A:521 152.0 0.676 S -68.6 163.6 152.0 0.676 0.0 HOH
 2.880
 O
 O
1rs0 1 P00751 99.4 0.0 X-RAY
 2004-12-14 ARG A:279 A:521 145.0 0.644 S -68.4 165.3 145.0 0.644 0.0 HOH
 2.623
 N
 O
1rtk 1 P00751 99.4 0.0 X-RAY
 2004-12-14 ARG A:279 A:521 150.0 0.667 S -74.7 162.5 150.0 0.667 0.0 HOH
 2.825
 N
 O
1dle 1 P00751 100.0 0.0 X-RAY
 2000-12-13 ARG A:80 A:81 147.0 0.653 S -79.2 146.5 147.0 0.653 0.0 HOH
 2.523
 O
 O
ARG B:80 B:81 142.0 0.631 S -67.8 148.1 142.0 0.631 0.0 HOH
 2.819
 O
 O
6qsw 1 P00751 100.0 0.0 X-RAY
 2019-03-27 ARG A:73 AAA:81 56.0 NA -57.2 136.3 56.0 NA NA HOH
 2.746
 O
 O
ARG B:73 BBB:81 159.0 0.707 -62.2 143.1 NA NA NA
ARG C:73 CCC:81 163.0 0.724 -56.2 136.0 NA NA NA
6qsx 1 P00751 100.0 0.0 X-RAY
 2019-03-27 ARG A:73 AAA:81 172.0 0.764 S -68.1 146.5 172.0 0.764 0.0 SO4
HOH
 2.029
2.791
 H
HA
 O2
O
ARG B:73 BBB:81 156.0 0.693 S -66.2 147.6 NA NA NA
6rav 1 P00751 100.0 0.0 X-RAY
 2019-04-17 ARG A:73 AAA:81 154.0 0.684 -55.0 138.9 154.0 0.684 0.0 SO4
HOH
 1.891
2.712
 H
HA
 O2
O
ARG B:73 BBB:81 164.0 0.729 S -66.3 144.6 NA NA NA
6t8u 1 P00751 100.0 0.0 X-RAY
 2020-03-04 ARG A:73 AAA:81 149.0 0.662 -58.3 138.8 149.0 0.662 0.0 HOH
 2.728
 NH1
 O
ARG B:73 BBB:81 150.0 0.667 -59.7 139.8 NA NA NA
ARG C:73 CCC:81 157.0 0.698 -58.8 139.0 NA NA NA
6t8v 1 P00751 100.0 0.0 X-RAY
 2020-03-04 ARG A:73 AAA:81 164.0 0.729 -64.5 142.6 164.0 0.729 0.0 SO4
HOH
 3.098
6.259
 N
CG
 O4
O
ARG B:73 BBB:81 168.0 0.747 S -69.7 147.1 NA NA NA
6t8w 1 P00751 100.0 0.0 X-RAY
 2020-03-04 ARG A:73 AAA:81 176.0 0.782 S -66.2 149.8 176.0 0.782 0.0 SO4
HOH
 2.800
2.876
 N
O
 O2
O
ARG B:73 BBB:81 165.0 0.733 S -64.3 149.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00751-f1 1 P00751 100.0 0.0 ARG A:546 A:546 177.0 0.787 S -89.0 122.4