Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 31918468 . A C CCDS4729.1:NM_001710.5:c.1697gAa>gCa_NP_001701.2:p.566E>A Homo sapiens complement factor B (CFB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7jtn 1 P00751 100.0 0.0 X-RAY
 2020-12-09 GLU A:566 A:541 201.0 1.0 T -73.4 1.0 201.0 1.0 0.0
GLU C:566 C:541 201.0 1.0 T -73.3 1.0 NA NA NA
7jtq 1 P00751 100.0 0.0 X-RAY
 2020-12-09 GLU A:566 A:541 194.0 1.0 T -75.4 11.2 194.0 1.0 0.0
GLU C:566 C:541 197.0 1.0 T -75.3 11.2 NA NA NA
2ok5 1 P00751 99.86 0.0 X-RAY
 2007-02-27 GLU A:551 A:541 194.0 1.0 T -70.0 -16.1 194.0 1.0 0.0 HOH
 3.167
 N
 O
2xwj 3 P00751 99.73 0.0 X-RAY
 2011-01-12 GLU I:541 I:541 200.0 1.0 G -64.0 -40.3 200.0 1.0 0.0
GLU J:541 J:541 198.0 1.0 G -64.2 -40.3 NA NA NA
GLU K:541 K:541 197.0 1.0 G -64.4 -40.3 NA NA NA
GLU L:541 L:541 198.0 1.0 G -63.7 -40.2 NA NA NA
3hrz 4 P00751 99.73 0.0 X-RAY
 2009-07-07 GLU D:541 D:541 156.0 0.821 G -76.6 -11.4 156.0 0.821 0.0 HOH
 4.952
 N
 O
3hs0 4 P00751 99.73 0.0 X-RAY
 2009-07-07 GLU D:541 D:541 201.0 1.0 G -82.6 13.0 NA NA NA
GLU H:541 I:541 179.0 0.942 G -69.2 -35.9 179.0 0.942 0.0
2xwb 3 P00751 99.73 0.0 X-RAY
 2011-01-12 GLU E:532 F:541 199.0 1.0 T -71.5 -41.9 199.0 1.0 0.0
GLU F:532 H:541 198.0 1.0 T -70.8 -42.7 NA NA NA
2win 3 P00751 100.0 0.0 X-RAY
 2009-06-09 GLU I:307 I:541 155.0 0.816 T -108.1 -43.6 NA NA NA
GLU J:307 J:541 157.0 0.826 T -108.0 -43.7 157.0 0.826 0.0
GLU K:307 K:541 156.0 0.821 T -108.0 -43.6 NA NA NA
GLU L:307 L:541 157.0 0.826 T -108.0 -43.6 157.0 0.826 0.0
6rur 5 P00751 99.6 0.0 X-RAY
 2019-08-21 GLU I:307 J:541 199.0 1.0 T -71.2 -28.2 199.0 1.0 0.0
GLU J:307 L:541 202.0 1.0 T -69.2 -27.7 202.0 1.0 0.0
6ruv 6 P00751 99.6 0.0 X-RAY
 2019-08-21 GLU K:307 J:541 203.0 1.0 T -69.7 -24.0 203.0 1.0 0.0
GLU L:307 L:541 205.0 1.0 T -69.7 -25.9 205.0 1.0 0.0
1rrk 1 P00751 99.4 0.0 X-RAY
 2004-12-14 GLU A:299 A:541 201.0 1.0 G -59.2 -33.8 201.0 1.0 0.0 HOH
 3.388
 CB
 O
1rs0 1 P00751 99.4 0.0 X-RAY
 2004-12-14 GLU A:299 A:541 199.0 1.0 T -59.0 -41.5 199.0 1.0 0.0 HOH
 4.659
 N
 O
1rtk 1 P00751 99.4 0.0 X-RAY
 2004-12-14 GLU A:299 A:541 195.0 1.0 G -62.2 -28.0 195.0 1.0 0.0 HOH
 4.718
 N
 O
1dle 1 P00751 100.0 0.0 X-RAY
 2000-12-13 GLU A:100 A:97 198.0 1.0 G -56.0 -22.5 198.0 1.0 0.0 HOH
 2.877
 OE1
 O
GLU B:100 B:97 181.0 0.953 G -67.5 -9.7 181.0 0.953 0.0 HOH
 2.589
 O
 O
6qsw 1 P00751 100.0 0.0 X-RAY
 2019-03-27 GLU A:93 AAA:97 207.0 1.0 G -61.0 -31.1 207.0 1.0 0.0 HOH
 2.020
 H
 O
GLU B:93 BBB:97 203.0 1.0 G -62.5 -30.7 NA NA NA
GLU C:93 CCC:97 200.0 1.0 G -46.6 -44.8 NA NA NA
6qsx 1 P00751 100.0 0.0 X-RAY
 2019-03-27 GLU A:93 AAA:97 185.0 0.974 G -67.6 -31.4 185.0 0.974 0.0 HOH
 2.016
 H
 O
GLU B:93 BBB:97 189.0 0.995 G -69.8 -28.0 NA NA NA
6rav 1 P00751 100.0 0.0 X-RAY
 2019-04-17 GLU A:93 AAA:97 184.0 0.968 G -60.7 -31.6 184.0 0.968 0.0 HOH
 2.758
 HG2
 O
GLU B:93 BBB:97 202.0 1.0 G -64.6 -30.6 NA NA NA
6t8u 1 P00751 100.0 0.0 X-RAY
 2020-03-04 GLU A:93 AAA:97 197.0 1.0 T -44.8 -38.2 197.0 1.0 0.0
GLU B:93 BBB:97 114.0 NA T -47.2 -37.9 NA NA NA
GLU C:93 CCC:97 188.0 0.989 T -45.7 -40.2 NA NA NA
6t8v 1 P00751 100.0 0.0 X-RAY
 2020-03-04 GLU A:93 AAA:97 185.0 0.974 G -45.7 -42.4 185.0 0.974 0.0 HOH
 6.051
 N
 O
GLU B:93 BBB:97 202.0 1.0 G -53.7 -37.0 NA NA NA
6t8w 1 P00751 100.0 0.0 X-RAY
 2020-03-04 GLU A:93 AAA:97 181.0 0.953 G -45.9 -41.5 181.0 0.953 0.0 HOH
 2.892
 OE1
 O
GLU B:93 BBB:97 200.0 1.0 G -56.3 -36.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00751-f1 1 P00751 100.0 0.0 GLU A:566 A:566 207.0 1.0 G -68.6 -25.5