Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 31919018 . T A CCDS4729.1:NM_001710.5:c.1953gaT>gaA_NP_001701.2:p.651D>E Homo sapiens complement factor B (CFB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7jtn 1 P00751 100.0 0.0 X-RAY
 2020-12-09 ASP A:651 A:626 167.0 1.0 S -91.5 -8.7 167.0 1.0 0.0
ASP C:651 C:626 167.0 1.0 S -91.5 -8.7 NA NA NA
7jtq 1 P00751 100.0 0.0 X-RAY
 2020-12-09 ASP A:651 A:626 137.0 0.913 S -90.7 -11.0 137.0 0.913 0.0
ASP C:651 C:626 138.0 0.92 S -90.7 -10.9 NA NA NA
2ok5 1 P00751 99.86 0.0 X-RAY
 2007-02-27 ASP A:636 A:626 144.0 0.96 T -62.9 -20.2 144.0 0.96 0.0 GOL
HOH
 9.540
2.797
 O
O
 O1
O
2xwj 3 P00751 99.73 0.0 X-RAY
 2011-01-12 ASP I:626 I:626 137.0 0.913 T -80.3 -9.1 63.0 0.42 0.493 A:P01024:0.493
ASP J:626 J:626 139.0 0.927 T -80.2 -8.1 NA NA NA
ASP K:626 K:626 139.0 0.927 T -80.1 -8.7 NA NA NA
ASP L:626 L:626 136.0 0.907 T -80.4 -8.5 NA NA NA
3hrz 4 P00751 99.73 0.0 X-RAY
 2009-07-07 ASP D:626 D:626 139.0 0.927 T -68.7 -19.4 139.0 0.927 0.0 HOH
 2.594
 O
 O
3hs0 4 P00751 99.73 0.0 X-RAY
 2009-07-07 ASP D:626 D:626 136.0 0.907 T -66.4 -21.7 NA NA NA
ASP H:626 I:626 141.0 0.94 T -69.3 -22.4 141.0 0.94 0.0
2xwb 3 P00751 99.73 0.0 X-RAY
 2011-01-12 ASP E:617 F:626 125.0 0.833 T -82.2 -14.9 68.0 0.453 0.38 A:P01024:0.38
ASP F:617 H:626 127.0 0.847 T -82.6 -15.2 NA NA NA
2win 3 P00751 100.0 0.0 X-RAY
 2009-06-09 ASP I:392 I:626 141.0 0.94 T -72.4 -28.0 NA NA NA
ASP J:392 J:626 141.0 0.94 T -72.4 -28.0 141.0 0.94 0.0
ASP K:392 K:626 140.0 0.933 T -72.4 -28.0 NA NA NA
ASP L:392 L:626 138.0 0.92 T -72.4 -28.0 138.0 0.92 0.0
6rur 5 P00751 99.6 0.0 X-RAY
 2019-08-21 ASP I:392 J:626 136.0 0.907 T -71.9 -27.4 136.0 0.907 0.0
ASP J:392 L:626 140.0 0.933 T -72.3 -26.0 140.0 0.933 0.0
6ruv 6 P00751 99.6 0.0 X-RAY
 2019-08-21 ASP K:392 J:626 140.0 0.933 T -72.2 -24.5 140.0 0.933 0.0
ASP L:392 L:626 141.0 0.94 T -72.8 -25.7 141.0 0.94 0.0
1rrk 1 P00751 99.4 0.0 X-RAY
 2004-12-14 ASP A:384 A:626 165.0 1.0 T -73.4 15.5 165.0 1.0 0.0 HOH
 3.239
 N
 O
1rs0 1 P00751 99.4 0.0 X-RAY
 2004-12-14 ASP A:384 A:626 168.0 1.0 T -69.2 4.8 168.0 1.0 0.0 HOH
 3.466
 OD2
 O
1rtk 1 P00751 99.4 0.0 X-RAY
 2004-12-14 ASP A:384 A:626 159.0 1.0 T -68.8 14.3 159.0 1.0 0.0 HOH
 3.366
 N
 O
1dle 1 P00751 100.0 0.0 X-RAY
 2000-12-13 ASP A:185 A:164 144.0 0.96 T -71.1 -10.1 144.0 0.96 0.0 HOH
 2.699
 O
 O
ASP B:185 B:164 171.0 1.0 T -65.4 -16.0 171.0 1.0 0.0 HOH
 2.738
 O
 O
6qsw 1 P00751 100.0 0.0 X-RAY
 2019-03-27 ASP A:178 AAA:164 177.0 1.0 T -64.7 -17.3 177.0 1.0 0.0 HOH
 2.458
 H
 O
ASP B:178 BBB:164 137.0 0.913 T -67.5 -12.2 NA NA NA
ASP C:178 CCC:164 178.0 1.0 T -64.7 -16.4 NA NA NA
6qsx 1 P00751 100.0 0.0 X-RAY
 2019-03-27 ASP A:178 AAA:164 159.0 1.0 T -72.8 -7.0 159.0 1.0 0.0 SO4
HOH
 4.403
2.652
 O
O
 O3
O
ASP B:178 BBB:164 175.0 1.0 T -63.1 -22.9 NA NA NA
6rav 1 P00751 100.0 0.0 X-RAY
 2019-04-17 ASP A:178 AAA:164 160.0 1.0 T -72.0 -11.4 160.0 1.0 0.0 SO4
HOH
 4.077
2.661
 O
O
 O2
O
ASP B:178 BBB:164 167.0 1.0 T -46.1 -38.6 NA NA NA
6t8u 1 P00751 100.0 0.0 X-RAY
 2020-03-04 ASP A:178 AAA:164 165.0 1.0 T -63.0 -19.5 165.0 1.0 0.0 HOH
 7.373
 O
 O
ASP B:178 BBB:164 138.0 0.92 T -58.0 -24.4 NA NA NA
ASP C:178 CCC:164 152.0 1.0 T -61.4 -16.5 NA NA NA
6t8v 1 P00751 100.0 0.0 X-RAY
 2020-03-04 ASP A:178 AAA:164 161.0 1.0 T -70.1 -13.9 161.0 1.0 0.0 SO4
HOH
 4.516
3.167
 O
N
 O3
O
ASP B:178 BBB:164 165.0 1.0 T -45.3 -36.3 NA NA NA
6t8w 1 P00751 100.0 0.0 X-RAY
 2020-03-04 ASP A:178 AAA:164 153.0 1.0 T -71.9 -13.1 153.0 1.0 0.0 SO4
HOH
 4.237
2.556
 O
O
 O2
O
ASP B:178 BBB:164 170.0 1.0 T -58.7 -25.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00751-f1 1 P00751 100.0 0.0 ASP A:651 A:651 172.0 1.0 G -59.8 -24.8