Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42928629 . A C CCDS4876.1:NM_018960.4:c.124Acc>Ccc_NP_061833.1:p.42T>P Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 THR A:42 A:41 36.0 0.257 -82.5 148.4 36.0 0.257 0.0
THR B:42 B:41 36.0 0.257 -81.7 156.2 36.0 0.257 0.0 HOH
 4.909
 O
 O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 THR A:41 A:41 37.0 0.264 -63.1 154.2 37.0 0.264 0.0
THR B:41 B:41 18.0 0.129 -81.4 154.4 18.0 0.129 0.0 HOH
 4.848
 O
 O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 THR A:41 A:41 23.0 0.164 -84.4 125.9 23.0 0.164 0.0 HOH
 6.371
 CG2
 O
THR B:41 B:41 27.0 0.193 -88.8 129.7 27.0 0.193 0.0 HOH
 6.533
 O
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 THR A:41 A:41 29.0 0.207 -96.1 141.8 29.0 0.207 0.0 HOH
 4.914
 N
 O
THR B:41 B:41 36.0 0.257 -87.3 145.4 36.0 0.257 0.0
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 THR A:41 A:41 15.0 0.107 H -63.7 -20.3 15.0 0.107 0.0 SAM
HOH
 9.144
5.997
 N
CG2
 O
O
THR B:41 B:41 15.0 0.107 H -63.9 -19.7 15.0 0.107 0.0 SAM
HOH
 8.965
5.292
 OG1
OG1
 O
O
THR C:41 C:41 15.0 0.107 H -66.0 -19.2 15.0 0.107 0.0 SAM
HOH
 9.051
8.428
 OG1
N
 O
O
THR D:41 D:41 15.0 0.107 H -61.9 -21.9 15.0 0.107 0.0 SAM
HOH
 8.925
4.285
 N
CG2
 O
O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 THR A:41 A:41 13.0 0.093 H -54.0 -25.6 13.0 0.093 0.0 SAM
HOH
 8.960
4.538
 OG1
OG1
 O
O
THR B:41 B:41 14.0 0.1 H -54.7 -24.3 14.0 0.1 0.0 SAM
HOH
 9.010
8.160
 OG1
O
 O
O
THR C:41 C:41 13.0 0.093 H -54.9 -24.7 13.0 0.093 0.0 SAM
HOH
 8.861
5.545
 OG1
OG1
 O
O
THR D:41 D:41 15.0 0.107 H -56.7 -24.7 15.0 0.107 0.0 SAM
HOH
 8.925
7.793
 OG1
O
 O
O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 THR A:41 A:41 7.0 0.05 -89.5 131.9 7.0 0.05 0.0
THR B:41 B:41 31.0 0.221 -69.2 135.7 31.0 0.221 0.0 SAM
 9.968
 N
 N
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 THR A:41 A:41 20.0 0.143 -91.7 145.4 20.0 0.143 0.0 HOH
 9.446
 CG2
 O
THR B:41 B:41 27.0 0.193 -74.0 154.6 27.0 0.193 0.0 HOH
 5.412
 O
 O
THR C:41 C:41 29.0 0.207 -91.4 151.0 29.0 0.207 0.0 HOH
 7.012
 N
 O
THR D:41 D:41 25.0 0.179 -80.0 151.3 25.0 0.179 0.0
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 THR A:41 A:41 17.0 0.121 -92.7 124.2 17.0 0.121 0.0
THR B:41 B:41 28.0 0.2 -79.9 156.0 28.0 0.2 0.0
THR C:41 C:41 25.0 0.179 -92.1 124.9 25.0 0.179 0.0
THR D:41 D:41 29.0 0.207 -80.6 155.7 29.0 0.207 0.0
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 THR A:42 A:41 16.0 0.114 -72.4 144.3 16.0 0.114 0.0 HOH
 4.830
 CG2
 O
THR B:42 B:41 36.0 0.257 -61.9 139.9 36.0 0.257 0.0 HOH
 3.763
 OG1
 O
THR C:42 C:41 36.0 0.257 -71.2 145.9 36.0 0.257 0.0 HOH
 3.459
 CG2
 O
THR D:42 D:41 23.0 0.164 -75.8 145.5 23.0 0.164 0.0 HOH
 3.548
 CA
 O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 THR A:42 A:41 20.0 0.143 -76.0 140.9 20.0 0.143 0.0 HOH
 5.051
 O
 O
THR B:42 B:41 24.0 0.171 -71.9 145.6 24.0 0.171 0.0 HOH
 3.632
 CA
 O
THR C:42 C:41 23.0 0.164 -71.3 142.9 23.0 0.164 0.0 HOH
 6.375
 N
 O
THR D:42 D:41 19.0 0.136 -77.3 137.9 19.0 0.136 0.0
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 THR A:41 A:41 17.0 0.121 -100.8 131.1 17.0 0.121 0.0 HOH
 4.696
 CA
 O
THR B:41 B:41 18.0 0.129 -83.6 141.2 18.0 0.129 0.0 HOH
 2.616
 O
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 THR A:41 A:41 17.0 0.121 360.0 93.3 17.0 0.121 0.0 HOH
 7.163
 N
 O
THR B:41 B:41 30.0 0.214 360.0 124.9 30.0 0.214 0.0 HOH
 5.610
 OG1
 O
THR C:41 C:41 51.0 0.364 360.0 116.9 51.0 0.364 0.0
THR D:41 D:41 45.0 0.321 360.0 126.4 45.0 0.321 0.0 HOH
 5.491
 C
 O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 THR A:41 A:41 24.0 0.171 H -73.7 -27.9 24.0 0.171 0.0 SAM
HOH
 8.884
5.302
 OG1
OG1
 O
O
THR B:41 B:41 23.0 0.164 H -70.8 -27.0 23.0 0.164 0.0 SAM
HOH
 8.962
4.482
 OG1
CG2
 O
O
THR C:41 C:41 22.0 0.157 H -72.3 -25.7 22.0 0.157 0.0 SAM
HOH
 8.832
6.269
 OG1
CG2
 O
O
THR D:41 D:41 21.0 0.15 H -75.4 -25.0 21.0 0.15 0.0 SAM
HOH
 8.926
4.901
 OG1
CG2
 O
O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 THR A:41 A:41 19.0 0.136 -71.9 140.1 19.0 0.136 0.0
THR B:41 B:41 22.0 0.157 -70.4 141.7 22.0 0.157 0.0
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 THR A:41 A:41 32.0 0.229 -62.1 135.6 32.0 0.229 0.0
THR B:41 B:41 28.0 0.2 -60.4 134.7 28.0 0.2 0.0
THR C:41 C:41 31.0 0.221 -59.4 132.8 31.0 0.221 0.0
THR D:41 D:41 31.0 0.221 -63.4 135.0 31.0 0.221 0.0
THR E:41 E:41 32.0 0.229 -60.1 140.2 NA NA NA
THR F:41 F:41 29.0 0.207 -59.7 136.1 NA NA NA
THR G:41 G:41 31.0 0.221 -59.2 137.8 NA NA NA
THR H:41 H:41 28.0 0.2 -63.9 135.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 THR A:42 A:42 16.0 0.114 H -62.1 -33.7