Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42930536 . A C CCDS4876.1:NM_018960.4:c.371gAt>gCt_NP_061833.1:p.124D>A Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 ASP A:124 A:123 64.0 0.427 H -78.4 -51.7 64.0 0.427 0.0 HOH
 7.348
 OD2
 O
ASP B:124 B:123 63.0 0.42 H -76.9 -48.3 63.0 0.42 0.0 HOH
 7.437
 OD2
 O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 ASP A:123 A:123 66.0 0.44 H -80.5 -45.1 66.0 0.44 0.0 HOH
 7.507
 OD2
 O
ASP B:123 B:123 62.0 0.413 H -81.3 -44.4 62.0 0.413 0.0 HOH
 7.511
 OD2
 O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 ASP A:123 A:123 64.0 0.427 T -152.9 -35.3 64.0 0.427 0.0 HOH
 3.376
 O
 O
ASP B:123 B:123 51.0 0.34 T -133.1 -24.3 51.0 0.34 0.0 HOH
 7.009
 OD2
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 ASP A:123 A:123 64.0 0.427 H -89.7 -31.5 64.0 0.427 0.0 HOH
 3.809
 OD1
 O
ASP B:123 B:123 61.0 0.407 H -92.8 -33.1 61.0 0.407 0.0 HOH
 6.505
 OD2
 O
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 ASP A:123 A:123 70.0 0.467 H -78.1 -45.0 70.0 0.467 0.0 SAM
HOH
 6.928
4.614
 OD2
O
 N1
O
ASP B:123 B:123 69.0 0.46 H -80.3 -44.9 69.0 0.46 0.0 SAM
HOH
 6.919
4.806
 OD2
O
 N1
O
ASP C:123 C:123 69.0 0.46 H -78.0 -45.9 69.0 0.46 0.0 SAM
HOH
 7.063
3.497
 OD2
OD2
 N1
O
ASP D:123 D:123 71.0 0.473 H -81.4 -45.5 71.0 0.473 0.0 SAM
HOH
 7.109
3.971
 OD2
O
 N1
O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 ASP A:123 A:123 70.0 0.467 H -76.4 -43.1 70.0 0.467 0.0 SAM
HOH
 7.060
4.456
 OD2
O
 N1
O
ASP B:123 B:123 69.0 0.46 H -78.5 -44.3 69.0 0.46 0.0 SAM
HOH
 7.058
3.409
 OD2
O
 N1
O
ASP C:123 C:123 70.0 0.467 H -77.6 -45.5 70.0 0.467 0.0 SAM
HOH
 7.018
4.794
 OD2
O
 N1
O
ASP D:123 D:123 70.0 0.467 H -76.2 -45.6 70.0 0.467 0.0 SAM
HOH
 7.038
2.643
 OD2
OD1
 N1
O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 ASP A:123 A:123 69.0 0.46 H -106.9 -29.7 69.0 0.46 0.0 HOH
 7.581
 OD2
 O
ASP B:123 B:123 49.0 0.327 H -86.3 -26.9 49.0 0.327 0.0 HOH
 7.596
 OD2
 O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 ASP A:123 A:123 57.0 0.38 H -64.2 -34.1 57.0 0.38 0.0 HOH
 9.511
 OD1
 O
ASP B:123 B:123 68.0 0.453 H -70.4 -23.7 68.0 0.453 0.0 HOH
 7.275
 OD1
 O
ASP C:123 C:123 57.0 0.38 H -64.5 -36.6 57.0 0.38 0.0 HOH
 7.942
 OD2
 O
ASP D:123 D:123 68.0 0.453 H -68.1 -27.1 68.0 0.453 0.0 HOH
 5.725
 OD1
 O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 ASP A:123 A:123 51.0 0.34 H -77.5 -26.4 51.0 0.34 0.0
ASP B:123 B:123 66.0 0.44 H -70.8 -28.8 66.0 0.44 0.0
ASP C:123 C:123 51.0 0.34 H -76.7 -27.0 51.0 0.34 0.0
ASP D:123 D:123 64.0 0.427 H -71.0 -29.0 64.0 0.427 0.0 HOH
 7.226
 OD1
 O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 ASP A:124 A:123 63.0 0.42 H -70.3 -25.5 63.0 0.42 0.0 HOH
 2.622
 OD2
 O
ASP B:124 B:123 62.0 0.413 H -77.9 -25.7 62.0 0.413 0.0 HOH
 2.783
 OD1
 O
ASP C:124 C:123 63.0 0.42 H -94.2 -24.3 63.0 0.42 0.0 C2F
HOH
 8.768
2.348
 O
OD1
 C13
O
ASP D:124 D:123 57.0 0.38 H -67.1 -18.5 57.0 0.38 0.0 HOH
 3.113
 O
 O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 ASP A:124 A:123 57.0 0.38 H -76.1 -29.5 57.0 0.38 0.0
ASP B:124 B:123 74.0 0.493 H -77.7 -16.0 74.0 0.493 0.0 HOH
 3.120
 OD1
 O
ASP C:124 C:123 76.0 0.507 H -73.2 -18.7 76.0 0.507 0.0 HOH
 6.594
 OD1
 O
ASP D:124 D:123 58.0 0.387 H -71.2 -32.5 58.0 0.387 0.0 HOH
 3.004
 OD2
 O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 ASP A:123 A:123 75.0 0.5 H -104.0 -25.4 75.0 0.5 0.0 HOH
 3.018
 OD1
 O
ASP B:123 B:123 71.0 0.473 H -102.4 -19.5 71.0 0.473 0.0 HOH
 3.619
 O
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 ASP A:123 A:123 71.0 0.473 H -81.9 -12.3 71.0 0.473 0.0 SAH
HOH
 8.470
6.264
 OD2
C
 N1
O
ASP B:123 B:123 77.0 0.513 H -93.5 -24.8 77.0 0.513 0.0 SAH
HOH
 8.570
2.686
 OD2
OD2
 C2
O
ASP C:123 C:123 46.0 0.307 H -80.9 -34.3 46.0 0.307 0.0 SAH
HOH
 7.634
6.129
 OD1
O
 N1
O
ASP D:123 D:123 60.0 0.4 G -120.3 -20.6 60.0 0.4 0.0 SAH
HOH
 8.369
3.522
 OD1
OD2
 N1
O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 ASP A:123 A:123 66.0 0.44 H -43.1 -43.9 66.0 0.44 0.0 SAM
HOH
 6.841
3.053
 OD2
OD1
 N1
O
ASP B:123 B:123 63.0 0.42 H -43.4 -41.6 63.0 0.42 0.0 SAM
HOH
 6.845
2.391
 OD2
OD1
 N1
O
ASP C:123 C:123 63.0 0.42 H -66.6 -52.2 63.0 0.42 0.0 SAM
HOH
 6.694
4.367
 OD2
O
 N1
O
ASP D:123 D:123 65.0 0.433 H -64.4 -53.9 65.0 0.433 0.0 SAM
HOH
 6.601
2.484
 OD2
OD1
 N1
O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 ASP A:123 A:123 73.0 0.487 G -153.2 -3.8 73.0 0.487 0.0 HOH
 9.316
 OD1
 O
ASP B:123 B:123 65.0 0.433 H -102.0 1.3 65.0 0.433 0.0 HOH
 7.313
 OD1
 O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 ASP A:123 A:123 70.0 0.467 H -112.0 -33.8 70.0 0.467 0.0
ASP B:123 B:123 72.0 0.48 H -90.7 -35.3 72.0 0.48 0.0
ASP C:123 C:123 69.0 0.46 H -89.5 -37.5 69.0 0.46 0.0 HOH
 6.458
 N
 O
ASP D:123 D:123 69.0 0.46 H -70.7 -32.9 69.0 0.46 0.0
ASP E:123 E:123 72.0 0.48 H -75.5 -32.7 NA NA NA
ASP F:123 F:123 71.0 0.473 H -75.2 -37.0 NA NA NA
ASP G:123 G:123 69.0 0.46 H -101.9 -31.4 NA NA NA
ASP H:123 H:123 66.0 0.44 H -111.9 -30.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 ASP A:124 A:124 65.0 0.433 H -73.9 -36.4