Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42930538 . G A CCDS4876.1:NM_018960.4:c.373Gtg>Atg_NP_061833.1:p.125V>M Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 VAL A:125 A:124 13.0 0.084 S -72.6 142.7 13.0 0.084 0.0 HOH
 7.594
 CG2
 O
VAL B:125 B:124 11.0 0.071 S -72.7 147.2 11.0 0.071 0.0 HOH
 7.790
 CG2
 O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 VAL A:124 A:124 17.0 0.11 -75.2 137.1 17.0 0.11 0.0 HOH
 8.405
 CG2
 O
VAL B:124 B:124 8.0 0.052 S -73.9 141.8 8.0 0.052 0.0 HOH
 7.404
 CG2
 O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 VAL A:124 A:124 10.0 0.065 S -138.8 124.9 10.0 0.065 0.0 HOH
 3.998
 CG2
 O
VAL B:124 B:124 14.0 0.09 S -142.3 124.8 14.0 0.09 0.0 HOH
 7.896
 CG2
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 VAL A:124 A:124 12.0 0.077 S -120.1 128.5 12.0 0.077 0.0 HOH
 4.749
 CG1
 O
VAL B:124 B:124 12.0 0.077 S -121.1 126.1 12.0 0.077 0.0 HOH
 9.227
 N
 O
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 VAL A:124 A:124 14.0 0.09 S -118.9 103.8 14.0 0.09 0.0 SAM
HOH
 9.065
4.434
 CG2
CG1
 C2
O
VAL B:124 B:124 15.0 0.097 S -119.1 104.6 15.0 0.097 0.0 SAM
HOH
 8.923
3.901
 CG2
O
 C2
O
VAL C:124 C:124 15.0 0.097 S -118.6 103.3 15.0 0.097 0.0 SAM
HOH
 9.138
6.871
 CG2
N
 C2
O
VAL D:124 D:124 14.0 0.09 S -118.8 105.3 14.0 0.09 0.0 SAM
HOH
 9.146
3.521
 CG2
CG1
 C2
O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 VAL A:124 A:124 14.0 0.09 S -118.9 101.4 14.0 0.09 0.0 SAM
HOH
 8.997
4.002
 CG2
CG1
 C2
O
VAL B:124 B:124 14.0 0.09 S -118.3 102.4 14.0 0.09 0.0 SAM
HOH
 9.026
3.575
 CG2
CG1
 C2
O
VAL C:124 C:124 15.0 0.097 S -117.2 101.7 15.0 0.097 0.0 SAM
HOH
 9.014
3.777
 CG2
O
 C2
O
VAL D:124 D:124 16.0 0.103 S -117.4 101.1 16.0 0.103 0.0 SAM
HOH
 9.021
7.158
 CG2
N
 C2
O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 VAL A:124 A:124 12.0 0.077 S -121.3 128.2 12.0 0.077 0.0 HOH
 7.966
 CG2
 O
VAL B:124 B:124 9.0 0.058 S -128.4 111.5 9.0 0.058 0.0 HOH
 7.883
 CG2
 O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 VAL A:124 A:124 15.0 0.097 S -127.4 110.6 15.0 0.097 0.0 HOH
 7.295
 CG1
 O
VAL B:124 B:124 15.0 0.097 S -134.0 139.6 15.0 0.097 0.0 HOH
 9.803
 CG1
 O
VAL C:124 C:124 17.0 0.11 S -125.8 109.3 17.0 0.11 0.0 HOH
 9.339
 CG2
 O
VAL D:124 D:124 15.0 0.097 S -132.5 138.1 15.0 0.097 0.0 HOH
 8.573
 CG1
 O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 VAL A:124 A:124 13.0 0.084 S -119.7 114.2 13.0 0.084 0.0
VAL B:124 B:124 11.0 0.071 S -123.1 127.3 11.0 0.071 0.0
VAL C:124 C:124 13.0 0.084 S -119.0 113.2 13.0 0.084 0.0
VAL D:124 D:124 12.0 0.077 S -123.0 127.3 12.0 0.077 0.0 HOH
 9.831
 CG1
 O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 VAL A:125 A:124 10.0 0.065 S -128.9 124.6 10.0 0.065 0.0 HOH
 2.626
 O
 O
VAL B:125 B:124 8.0 0.052 S -113.9 128.2 8.0 0.052 0.0 HOH
 7.817
 N
 O
VAL C:125 C:124 6.0 0.039 S -124.2 103.4 6.0 0.039 0.0 C2F
HOH
 6.515
2.739
 C
O
 C16
O
VAL D:125 D:124 14.0 0.09 S -141.9 100.2 14.0 0.09 0.0 HOH
 5.209
 CG2
 O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 VAL A:125 A:124 10.0 0.065 S -121.8 116.4 10.0 0.065 0.0
VAL B:125 B:124 10.0 0.065 S -136.7 118.8 10.0 0.065 0.0 HOH
 8.157
 N
 O
VAL C:125 C:124 11.0 0.071 S -133.6 120.7 11.0 0.071 0.0 HOH
 9.095
 CG2
 O
VAL D:125 D:124 12.0 0.077 S -118.9 123.3 12.0 0.077 0.0 HOH
 5.521
 O
 O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 VAL A:124 A:124 10.0 0.065 S -122.1 127.5 10.0 0.065 0.0 HOH
 3.976
 C
 O
VAL B:124 B:124 14.0 0.09 S -131.5 126.3 14.0 0.09 0.0 HOH
 4.328
 CG1
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 VAL A:124 A:124 7.0 0.045 -143.6 105.3 7.0 0.045 0.0 SAH
HOH
 9.525
6.548
 CG2
N
 C2
O
VAL B:124 B:124 6.0 0.039 S -124.8 120.0 6.0 0.039 0.0 SAH
HOH
 9.129
6.582
 CG2
O
 C2
O
VAL C:124 C:124 14.0 0.09 S -124.1 94.5 14.0 0.09 0.0 SAH
HOH
 9.514
7.582
 CG2
O
 C2
O
VAL D:124 D:124 11.0 0.071 S -139.8 102.9 11.0 0.071 0.0 SAH
HOH
 9.789
3.768
 CG2
O
 C2
O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 VAL A:124 A:124 14.0 0.09 S -133.5 106.4 14.0 0.09 0.0 SAM
HOH
 8.782
6.834
 CG2
O
 C2
O
VAL B:124 B:124 14.0 0.09 S -135.7 104.4 14.0 0.09 0.0 SAM
HOH
 8.737
5.759
 CG2
O
 C2
O
VAL C:124 C:124 13.0 0.084 S -114.7 106.9 13.0 0.084 0.0 SAM
HOH
 9.027
4.682
 CG2
CG1
 C2
O
VAL D:124 D:124 13.0 0.084 S -115.3 108.2 13.0 0.084 0.0 SAM
HOH
 9.014
5.691
 CG2
N
 C2
O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 VAL A:124 A:124 10.0 0.065 S -157.4 104.5 10.0 0.065 0.0
VAL B:124 B:124 6.0 0.039 S -154.2 108.0 6.0 0.039 0.0 HOH
 8.088
 CG2
 O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 VAL A:124 A:124 6.0 0.039 S -119.6 138.5 6.0 0.039 0.0
VAL B:124 B:124 6.0 0.039 S -108.1 126.9 6.0 0.039 0.0
VAL C:124 C:124 5.0 0.032 S -114.4 121.8 5.0 0.032 0.0 HOH
 5.055
 O
 O
VAL D:124 D:124 7.0 0.045 S -117.4 133.4 7.0 0.045 0.0
VAL E:124 E:124 6.0 0.039 S -115.9 125.2 NA NA NA
VAL F:124 F:124 5.0 0.032 S -112.7 106.6 NA NA NA
VAL G:124 G:124 5.0 0.032 S -119.8 125.1 NA NA NA
VAL H:124 H:124 5.0 0.032 S -119.2 119.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 VAL A:125 A:125 8.0 0.052 S -111.5 108.8