Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42930587 . A C CCDS4876.1:NM_018960.4:c.422aAc>aCc_NP_061833.1:p.141N>T Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 ASN A:141 A:140 7.0 0.044 S 74.4 26.8 7.0 0.044 0.0 CIT
HOH
 3.061
5.941
 ND2
N
 O5
O
ASN B:141 B:140 7.0 0.044 S 79.4 25.8 7.0 0.044 0.0 CIT
HOH
 3.178
2.856
 ND2
OD1
 O5
O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 ASN A:140 A:140 7.0 0.044 S 67.4 36.7 7.0 0.044 0.0 CIT
 3.384
 ND2
 O5
ASN B:140 B:140 8.0 0.05 S 71.8 32.3 8.0 0.05 0.0 CIT
HOH
 3.082
2.826
 ND2
OD1
 O5
O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 ASN A:138 A:138 7.0 0.044 T 68.9 35.3 7.0 0.044 0.0 HOH
 4.166
 ND2
 O
ASN B:138 B:138 9.0 0.056 S 58.3 27.5 9.0 0.056 0.0 HOH
 3.887
 ND2
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 ASN A:138 A:138 8.0 0.05 S 62.3 32.5 8.0 0.05 0.0 HOH
 2.579
 OD1
 O
ASN B:138 B:138 9.0 0.056 S 56.1 34.4 9.0 0.056 0.0 HOH
 7.360
 O
 O
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 ASN A:138 A:138 2.0 0.013 S 58.6 52.6 2.0 0.013 0.0 ACT
SAM
HOH
 2.785
4.062
7.463
 ND2
O
N
 O
CE
O
ASN B:138 B:138 2.0 0.013 S 58.8 54.1 2.0 0.013 0.0 ACT
SAM
HOH
 2.795
4.019
8.330
 ND2
O
N
 O
CE
O
ASN C:138 C:138 3.0 0.019 S 58.3 54.3 3.0 0.019 0.0 ACT
SAM
HOH
 2.748
3.947
4.173
 ND2
O
C
 O
CE
O
ASN D:138 D:138 2.0 0.013 S 58.0 51.8 2.0 0.013 0.0 ACT
SAM
HOH
 2.919
4.244
7.687
 ND2
O
N
 CH3
CE
O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 ASN A:138 A:138 3.0 0.019 T 59.5 54.8 3.0 0.019 0.0 ACT
SAM
HOH
 2.793
4.041
7.390
 ND2
O
N
 O
CE
O
ASN B:138 B:138 2.0 0.013 T 57.0 54.7 2.0 0.013 0.0 ACT
SAM
HOH
 2.793
4.070
7.992
 ND2
O
ND2
 O
CE
O
ASN C:138 C:138 3.0 0.019 T 60.5 54.4 3.0 0.019 0.0 ACT
SAM
HOH
 2.778
4.074
8.107
 ND2
O
N
 O
CE
O
ASN D:138 D:138 3.0 0.019 T 58.9 55.0 3.0 0.019 0.0 ACT
SAM
HOH
 2.776
4.021
7.804
 ND2
O
N
 O
CE
O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 ASN A:138 A:138 0.0 0.0 S 72.5 34.0 0.0 0.0 0.0 ACT
SAM
HOH
 7.874
4.505
2.720
 O
ND2
OD1
 CH3
C8
O
ASN B:138 B:138 0.0 0.0 S 68.7 45.7 0.0 0.0 0.0 ACT
SAM
HOH
 7.189
3.174
3.338
 O
O
CA
 CH3
O3'
O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 ASN A:138 A:138 5.0 0.031 S 60.8 49.1 5.0 0.031 0.0 HOH
 3.509
 CA
 O
ASN B:138 B:138 6.0 0.037 S 54.4 35.2 6.0 0.037 0.0 HOH
 2.879
 OD1
 O
ASN C:138 C:138 5.0 0.031 T 54.9 42.1 5.0 0.031 0.0 HOH
 2.626
 OD1
 O
ASN D:138 D:138 6.0 0.037 S 57.8 32.8 6.0 0.037 0.0 CA
HOH
 6.252
2.767
 O
OD1
 CA
O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 ASN A:138 A:138 6.0 0.037 S 68.1 24.0 6.0 0.037 0.0
ASN B:138 B:138 6.0 0.037 S 59.2 37.4 6.0 0.037 0.0 HOH
 2.712
 OD1
 O
ASN C:138 C:138 6.0 0.037 S 67.0 25.1 6.0 0.037 0.0
ASN D:138 D:138 6.0 0.037 S 58.9 37.0 6.0 0.037 0.0 HOH
 9.817
 N
 O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 ASN A:139 A:138 8.0 0.05 T 68.8 28.7 8.0 0.05 0.0 TAM
HOH
 3.889
2.800
 C
OD1
 O4
O
ASN B:139 B:138 8.0 0.05 S 66.2 32.5 8.0 0.05 0.0 HOH
 2.721
 OD1
 O
ASN C:139 C:138 9.0 0.056 S 60.2 29.9 9.0 0.056 0.0 TAM
HOH
 4.641
2.761
 N
OD1
 O4
O
ASN D:139 D:138 9.0 0.056 T 75.7 25.9 9.0 0.056 0.0 TAM
HOH
 4.483
2.701
 N
ND2
 O5
O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 ASN A:139 A:138 8.0 0.05 S 66.4 33.7 8.0 0.05 0.0 HOH
 2.874
 OD1
 O
ASN B:139 B:138 9.0 0.056 S 74.4 25.5 9.0 0.056 0.0 TAM
HOH
 4.736
2.711
 CB
OD1
 O5
O
ASN C:139 C:138 8.0 0.05 S 77.2 23.1 8.0 0.05 0.0 HOH
 3.695
 ND2
 O
ASN D:139 D:138 7.0 0.044 S 66.4 34.3 7.0 0.044 0.0 HOH
 2.834
 ND2
 O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 ASN A:138 A:138 5.0 0.031 S 64.8 40.1 5.0 0.031 0.0 HOH
 2.609
 OD1
 O
ASN B:138 B:138 7.0 0.044 S 62.1 37.0 7.0 0.044 0.0 HOH
 2.902
 ND2
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 ASN A:138 A:138 1.0 0.006 S 53.7 38.3 1.0 0.006 0.0 SAH
HOH
 4.993
5.178
 O
ND2
 SD
O
ASN B:138 B:138 0.0 0.0 S 47.3 26.6 0.0 0.0 0.0 SAH
HOH
 5.777
3.962
 C
CB
 SD
O
ASN C:138 C:138 4.0 0.025 T 38.9 44.2 4.0 0.025 0.0 SAH
HOH
 5.337
4.072
 O
C
 SD
O
ASN D:138 D:138 12.0 0.075 S 43.8 39.3 12.0 0.075 0.0 SAH
HOH
 4.783
8.081
 O
N
 SD
O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 ASN A:138 A:138 6.0 0.037 S 57.5 51.7 6.0 0.037 0.0 SAM
HOH
 4.571
2.564
 O
ND2
 CE
O
ASN B:138 B:138 6.0 0.037 S 60.4 51.9 6.0 0.037 0.0 SAM
HOH
 4.607
4.579
 O
ND2
 CE
O
ASN C:138 C:138 4.0 0.025 T 58.8 41.9 4.0 0.025 0.0 SAM
HOH
 4.488
7.298
 O
ND2
 CE
O
ASN D:138 D:138 4.0 0.025 T 60.6 39.5 4.0 0.025 0.0 SAM
HOH
 4.609
7.393
 O
N
 CE
O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 ASN A:138 A:138 8.0 0.05 T 79.8 35.2 8.0 0.05 0.0 TRS
 5.896
 N
 O3
ASN B:138 B:138 9.0 0.056 S 82.8 31.8 9.0 0.056 0.0 TRS
HOH
 6.076
3.508
 N
C
 C3
O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 ASN A:138 A:138 8.0 0.05 T 55.8 27.9 8.0 0.05 0.0 BME
 7.646
 ND2
 O1
ASN B:138 B:138 6.0 0.037 S 51.8 27.7 6.0 0.037 0.0
ASN C:138 C:138 7.0 0.044 T 65.4 20.7 7.0 0.044 0.0 HOH
 7.135
 N
 O
ASN D:138 D:138 7.0 0.044 T 59.2 26.0 7.0 0.044 0.0 HOH
 3.401
 ND2
 O
ASN E:138 E:138 7.0 0.044 T 55.0 28.6 NA NA NA
ASN F:138 F:138 7.0 0.044 T 61.9 27.1 NA NA NA
ASN G:138 G:138 8.0 0.05 T 58.8 26.0 NA NA NA
ASN H:138 H:138 7.0 0.044 T 58.6 20.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 ASN A:141 A:141 6.0 0.037 S 62.4 27.7