Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42930888 . A C CCDS4876.1:NM_018960.4:c.530cAt>cCt_NP_061833.1:p.177H>P Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 ASN A:177 A:176 1.0 0.006 E -141.1 138.2 1.0 0.006 0.0 BME
CIT
HOH
 9.698
6.823
8.967
 O
C
ND2
 S2
O6
O
ASN B:177 B:176 1.0 0.006 E -146.7 137.1 1.0 0.006 0.0 BME
BME
CIT
HOH
 9.691
9.379
7.184
3.750
 ND2
O
C
CA
 S2
C2
O5
O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 HIS A:176 A:176 1.0 0.005 E -158.7 140.2 1.0 0.005 0.0 CIT
 7.084
 C
 O5
HIS B:176 B:176 1.0 0.005 E -149.9 149.9 1.0 0.005 0.0 BME
CIT
HOH
 9.677
7.106
3.277
 O
C
CE1
 S2
O5
O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 HIS A:174 A:174 1.0 0.005 E -165.3 159.9 1.0 0.005 0.0 HOH
 2.550
 NE2
 O
HIS B:174 B:174 1.0 0.005 E -163.9 152.8 1.0 0.005 0.0 HOH
 8.189
 NE2
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 HIS A:174 A:174 0.0 0.0 E -159.7 158.0 0.0 0.0 0.0 HOH
 3.251
 CA
 O
HIS B:174 B:174 1.0 0.005 E -155.7 154.3 1.0 0.005 0.0
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 HIS A:174 A:174 0.0 0.0 E -167.9 151.4 0.0 0.0 0.0 ACT
SAM
HOH
 7.253
9.839
3.307
 C
CA
NE2
 O
CE
O
HIS B:174 B:174 0.0 0.0 E -167.0 153.1 0.0 0.0 0.0 ACT
SAM
HOH
 7.276
9.697
8.680
 C
CA
NE2
 O
CE
O
HIS C:174 C:174 1.0 0.005 E -167.1 151.1 1.0 0.005 0.0 ACT
SAM
HOH
 7.247
9.679
4.585
 C
CA
N
 O
CE
O
HIS D:174 D:174 0.0 0.0 E -166.5 150.4 0.0 0.0 0.0 ACT
SAM
HOH
 7.491
9.863
7.941
 C
CA
CE1
 CH3
CE
O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 HIS A:174 A:174 0.0 0.0 E -165.6 154.0 0.0 0.0 0.0 ACT
SAM
HOH
 7.348
9.807
3.250
 C
CA
CE1
 O
CE
O
HIS B:174 B:174 0.0 0.0 E -165.8 152.7 0.0 0.0 0.0 ACT
SAM
HOH
 7.315
9.776
8.476
 C
CA
CE1
 O
CE
O
HIS C:174 C:174 0.0 0.0 E -165.5 155.3 0.0 0.0 0.0 ACT
SAM
HOH
 7.348
9.810
8.470
 C
CA
CE1
 O
CE
O
HIS D:174 D:174 1.0 0.005 E -165.2 151.7 1.0 0.005 0.0 ACT
SAM
HOH
 7.355
9.812
3.088
 C
CA
CE1
 O
CE
O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 HIS A:174 A:174 2.0 0.01 E -154.9 154.0 2.0 0.01 0.0 SAM
HOH
 8.135
3.553
 C
CB
 C8
O
HIS B:174 B:174 1.0 0.005 E -153.4 151.1 1.0 0.005 0.0 SAM
HOH
 7.369
2.940
 C
NE2
 C8
O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 HIS A:174 A:174 0.0 0.0 E -173.6 151.9 0.0 0.0 0.0 HOH
 3.665
 CE1
 O
HIS B:174 B:174 1.0 0.005 E -162.8 151.2 1.0 0.005 0.0 HOH
 3.238
 CD2
 O
HIS C:174 C:174 0.0 0.0 E -166.6 150.1 0.0 0.0 0.0 HOH
 3.298
 CB
 O
HIS D:174 D:174 0.0 0.0 E -163.1 149.7 0.0 0.0 0.0 HOH
 3.374
 NE2
 O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 HIS A:174 A:174 0.0 0.0 E -163.6 139.9 0.0 0.0 0.0
HIS B:174 B:174 1.0 0.005 E -159.6 152.7 1.0 0.005 0.0 HOH
 2.947
 NE2
 O
HIS C:174 C:174 0.0 0.0 E -163.5 139.9 0.0 0.0 0.0
HIS D:174 D:174 1.0 0.005 E -157.8 151.9 1.0 0.005 0.0 HOH
 9.595
 CD2
 O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 HIS A:175 A:174 1.0 0.005 E -156.5 145.3 1.0 0.005 0.0 TAM
HOH
 9.000
3.046
 CA
CE1
 O4
O
HIS B:175 B:174 1.0 0.005 E -152.4 152.4 1.0 0.005 0.0 HOH
 3.111
 CE1
 O
HIS C:175 C:174 1.0 0.005 E -146.3 155.1 1.0 0.005 0.0 TAM
HOH
 8.874
2.930
 C
CE1
 O4
O
HIS D:175 D:174 1.0 0.005 E -149.2 149.3 1.0 0.005 0.0 TAM
HOH
 8.624
3.102
 C
ND1
 O5
O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 HIS A:175 A:174 1.0 0.005 E -142.3 158.9 1.0 0.005 0.0 HOH
 3.393
 CA
 O
HIS B:175 B:174 1.0 0.005 E -156.0 151.0 1.0 0.005 0.0 TAM
HOH
 8.684
3.328
 C
CB
 O5
O
HIS C:175 C:174 1.0 0.005 E -156.0 148.0 1.0 0.005 0.0 HOH
 3.229
 CE1
 O
HIS D:175 D:174 1.0 0.005 E -149.1 159.7 1.0 0.005 0.0 HOH
 3.363
 CE1
 O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 HIS A:174 A:174 1.0 0.005 E -161.9 153.0 1.0 0.005 0.0 HOH
 3.500
 CA
 O
HIS B:174 B:174 0.0 0.0 E -163.6 151.6 0.0 0.0 0.0 HOH
 3.701
 CB
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 HIS A:174 A:174 1.0 0.005 E -147.8 147.1 1.0 0.005 0.0 HOH
 8.493
 NE2
 O
HIS B:174 B:174 0.0 0.0 E -146.3 148.4 0.0 0.0 0.0 HOH
 7.251
 C
 O
HIS C:174 C:174 0.0 0.0 E -168.2 131.3 0.0 0.0 0.0 HOH
 4.974
 N
 O
HIS D:174 D:174 0.0 0.0 E -174.5 149.4 0.0 0.0 0.0 SAH
 9.700
 N
 N
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 HIS A:174 A:174 1.0 0.005 E -156.2 141.4 1.0 0.005 0.0 HOH
 6.583
 C
 O
HIS B:174 B:174 1.0 0.005 E -158.3 143.5 1.0 0.005 0.0 HOH
 7.928
 NE2
 O
HIS C:174 C:174 0.0 0.0 E -169.3 151.0 0.0 0.0 0.0 SAM
HOH
 9.860
7.481
 CA
O
 CE
O
HIS D:174 D:174 0.0 0.0 E -167.7 151.5 0.0 0.0 0.0 SAM
 9.904
 CA
 CE
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 HIS A:174 A:174 1.0 0.005 E -149.7 155.0 1.0 0.005 0.0 BME
HOH
 9.932
9.101
 NE2
O
 S2
O
HIS B:174 B:174 2.0 0.01 E -148.0 153.6 2.0 0.01 0.0 HOH
 4.919
 N
 O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 HIS A:174 A:174 1.0 0.005 E -159.7 146.1 1.0 0.005 0.0 BME
 7.255
 O
 O1
HIS B:174 B:174 0.0 0.0 E -156.6 152.9 0.0 0.0 0.0
HIS C:174 C:174 1.0 0.005 E -160.5 149.1 1.0 0.005 0.0
HIS D:174 D:174 1.0 0.005 E -157.3 150.0 1.0 0.005 0.0 BME
HOH
 9.871
7.823
 CE1
C
 S2
O
HIS E:174 E:174 1.0 0.005 E -154.3 153.1 NA NA NA
HIS F:174 F:174 1.0 0.005 E -160.5 147.7 NA NA NA
HIS G:174 G:174 1.0 0.005 E -160.5 150.5 NA NA NA
HIS H:174 H:174 1.0 0.005 E -162.0 148.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 HIS A:177 A:177 0.0 0.0 E -148.7 157.5