Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42930903 . A C CCDS4876.1:NM_018960.4:c.545cAc>cCc_NP_061833.1:p.182H>P Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 HIS A:182 A:181 78.0 0.4 H -59.0 -41.7 78.0 0.4 0.0 BME
BME
HOH
 9.337
4.913
5.643
 CD2
NE2
N
 O1
C1
O
HIS B:182 B:181 78.0 0.4 H -54.7 -44.8 78.0 0.4 0.0 BME
BME
BME
HOH
 9.392
7.473
3.206
3.497
 O
N
NE2
CA
 S2
S2
O1
O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 HIS A:181 A:181 84.0 0.431 H -65.2 -32.0 84.0 0.431 0.0 BME
 9.652
 O
 S2
HIS B:181 B:181 74.0 0.379 H -63.1 -35.3 74.0 0.379 0.0 BME
BME
HOH
 9.299
4.091
2.669
 O
ND1
CD2
 S2
C1
O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 TYR A:179 A:179 119.0 0.517 H -84.5 -50.6 119.0 0.517 0.0 HOH
 3.226
 CE1
 O
TYR B:179 B:179 113.0 0.491 H -67.3 -48.9 113.0 0.491 0.0 HOH
 3.379
 OH
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 TYR A:179 A:179 94.0 0.409 H -63.9 -41.2 94.0 0.409 0.0 HOH
 3.691
 OH
 O
TYR B:179 B:179 87.0 0.378 H -84.8 -40.3 87.0 0.378 0.0
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 TYR A:179 A:179 86.0 0.374 H -90.1 -43.4 86.0 0.374 0.0 HOH
 3.477
 CE2
 O
TYR B:179 B:179 83.0 0.361 H -90.8 -42.2 83.0 0.361 0.0 HOH
 5.204
 N
 O
TYR C:179 C:179 83.0 0.361 H -91.7 -42.3 83.0 0.361 0.0 HOH
 7.208
 O
 O
TYR D:179 D:179 83.0 0.361 H -88.6 -42.9 83.0 0.361 0.0 HOH
 3.900
 CD1
 O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 TYR A:179 A:179 84.0 0.365 H -94.0 -45.8 84.0 0.365 0.0 HOH
 3.104
 OH
 O
TYR B:179 B:179 84.0 0.365 H -91.9 -45.1 84.0 0.365 0.0 HOH
 7.207
 N
 O
TYR C:179 C:179 83.0 0.361 H -93.7 -45.0 83.0 0.361 0.0 HOH
 3.410
 CE2
 O
TYR D:179 D:179 82.0 0.357 H -94.0 -44.8 82.0 0.357 0.0 HOH
 3.554
 OH
 O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 TYR A:179 A:179 95.0 0.413 H -63.9 -43.7 95.0 0.413 0.0 HOH
 7.756
 CE2
 O
TYR B:179 B:179 77.0 0.335 H -65.6 -59.3 77.0 0.335 0.0 SAM
HOH
 8.902
6.058
 CE2
N
 N6
O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 TYR A:179 A:179 86.0 0.374 H -78.9 -29.0 86.0 0.374 0.0 HOH
 5.339
 N
 O
TYR B:179 B:179 77.0 0.335 H -66.7 -42.4 77.0 0.335 0.0 HOH
 5.657
 CD2
 O
TYR C:179 C:179 106.0 0.461 H -79.2 -37.0 106.0 0.461 0.0
TYR D:179 D:179 77.0 0.335 H -63.6 -49.0 77.0 0.335 0.0 CA
HOH
 8.190
3.245
 O
CD2
 CA
O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 TYR A:179 A:179 95.0 0.413 H -79.8 -41.6 95.0 0.413 0.0
TYR B:179 B:179 91.0 0.396 H -78.0 -44.5 91.0 0.396 0.0 HOH
 6.126
 N
 O
TYR C:179 C:179 100.0 0.435 H -79.5 -41.5 100.0 0.435 0.0
TYR D:179 D:179 91.0 0.396 H -78.3 -45.3 91.0 0.396 0.0 HOH
 7.838
 CB
 O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 TYR A:180 A:179 99.0 0.43 H -62.6 -49.2 99.0 0.43 0.0 HOH
 2.992
 OH
 O
TYR B:180 B:179 98.0 0.426 H -63.2 -46.1 98.0 0.426 0.0 C2F
HOH
 6.544
3.548
 CE1
CD2
 O4
O
TYR C:180 C:179 127.0 0.552 H -69.9 -48.5 127.0 0.552 0.0 HOH
 2.554
 OH
 O
TYR D:180 D:179 124.0 0.539 H -65.8 -42.7 124.0 0.539 0.0 HOH
 3.664
 CB
 O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 TYR A:180 A:179 109.0 0.474 H -57.9 -50.3 109.0 0.474 0.0 HOH
 9.642
 CE1
 O
TYR B:180 B:179 103.0 0.448 H -67.8 -41.4 103.0 0.448 0.0 BME
HOH
 7.679
5.833
 OH
N
 S2
O
TYR C:180 C:179 99.0 0.43 H -71.1 -41.9 99.0 0.43 0.0 HOH
 6.121
 N
 O
TYR D:180 D:179 112.0 0.487 H -54.3 -51.0 112.0 0.487 0.0 HOH
 3.802
 CB
 O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 TYR A:179 A:179 96.0 0.417 H -63.4 -47.9 96.0 0.417 0.0 HOH
 3.893
 CD1
 O
TYR B:179 B:179 98.0 0.426 H -72.3 -44.5 98.0 0.426 0.0 HOH
 3.852
 CD1
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 TYR A:179 A:179 110.0 0.478 H -70.5 -38.4 110.0 0.478 0.0 HOH
 4.469
 CB
 O
TYR B:179 B:179 99.0 0.43 H -70.1 -57.6 99.0 0.43 0.0 HOH
 7.804
 N
 O
TYR C:179 C:179 82.0 0.357 T -64.8 -44.3 82.0 0.357 0.0 HOH
 3.025
 CE2
 O
TYR D:179 D:179 96.0 0.417 H -50.4 -61.4 96.0 0.417 0.0 HOH
 6.085
 O
 O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 TYR A:179 A:179 90.0 0.391 H -73.9 -41.6 90.0 0.391 0.0 HOH
 2.621
 OH
 O
TYR B:179 B:179 91.0 0.396 H -70.7 -43.9 91.0 0.396 0.0 HOH
 4.640
 N
 O
TYR C:179 C:179 84.0 0.365 H -67.2 -44.3 84.0 0.365 0.0 HOH
 4.646
 CB
 O
TYR D:179 D:179 83.0 0.361 H -67.6 -44.4 83.0 0.361 0.0 HOH
 2.379
 OH
 O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 TYR A:179 A:179 104.0 0.452 H -57.6 -54.9 104.0 0.452 0.0 BME
HOH
 7.521
4.314
 N
CD2
 S2
O
TYR B:179 B:179 108.0 0.47 H -57.4 -50.5 108.0 0.47 0.0 HOH
 5.931
 N
 O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 TYR A:179 A:179 107.0 0.465 H -65.8 -54.0 107.0 0.465 0.0 BME
 3.858
 CD2
 C2
TYR B:179 B:179 109.0 0.474 H -63.0 -53.4 109.0 0.474 0.0
TYR C:179 C:179 109.0 0.474 H -65.1 -53.7 109.0 0.474 0.0
TYR D:179 D:179 109.0 0.474 H -66.0 -53.5 109.0 0.474 0.0 BME
BME
 8.941
8.287
 CE2
N
 C1
S2
TYR E:179 E:179 105.0 0.457 H -69.5 -49.2 NA NA NA
TYR F:179 F:179 108.0 0.47 H -70.6 -51.4 NA NA NA
TYR G:179 G:179 110.0 0.478 H -66.1 -53.4 NA NA NA
TYR H:179 H:179 106.0 0.461 H -66.0 -52.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 HIS A:182 A:182 32.0 0.164 H -68.7 -42.6