Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42931106 . T A CCDS4876.1:NM_018960.4:c.635gTg>gAg_NP_061833.1:p.212V>E Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 VAL A:212 A:211 66.0 0.426 E -108.3 118.8 36.0 0.232 0.194 A:Q14749:0.194
 BME
HOH
 5.887
2.760
 C
O
 S2
O
VAL B:212 B:211 66.0 0.426 E -106.5 124.2 36.0 0.232 0.194 B:Q14749:0.194
 BME
HOH
 5.933
4.549
 C
CG2
 S2
O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 VAL A:211 A:211 66.0 0.426 E -105.9 119.9 36.0 0.232 0.194 A:Q14749:0.194
 BME
 5.881
 C
 S2
VAL B:211 B:211 63.0 0.406 E -102.2 120.9 33.0 0.213 0.193 B:Q14749:0.194
 BME
HOH
 6.049
3.762
 C
O
 S2
O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 VAL A:209 A:209 51.0 0.329 E -104.6 110.3 20.0 0.129 0.2 B:P13255:0.2
 HOH
 4.549
 CG2
 O
VAL B:209 B:209 58.0 0.374 E -109.9 113.1 25.0 0.161 0.213 B:P13255:0.006
A:P13255:0.206
 HOH
 3.812
 CG1
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 VAL A:209 A:209 57.0 0.368 S -62.8 -164.2 57.0 0.368 0.0 HOH
 3.993
 CG1
 O
VAL B:209 B:209 57.0 0.368 S -64.8 -162.3 57.0 0.368 0.0 HOH
 9.807
 CG2
 O
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 VAL A:209 A:209 60.0 0.387 E -82.4 129.9 33.0 0.213 0.174 C:P13255:0.174
 HOH
 3.383
 CG1
 O
VAL B:209 B:209 59.0 0.381 E -83.4 131.0 28.0 0.181 0.2 D:P13255:0.2
 HOH
 4.148
 CG2
 O
VAL C:209 C:209 59.0 0.381 E -83.5 128.0 23.0 0.148 0.233 A:P13255:0.232
 HOH
 3.867
 CG2
 O
VAL D:209 D:209 59.0 0.381 E -83.9 128.6 25.0 0.161 0.22 B:P13255:0.219
 HOH
 6.703
 N
 O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 VAL A:209 A:209 70.0 0.452 E -103.0 128.0 41.0 0.265 0.187 D:P13255:0.187
 HOH
 3.831
 CG2
 O
VAL B:209 B:209 69.0 0.445 E -101.0 126.1 34.0 0.219 0.226 C:P13255:0.226
 HOH
 3.772
 CG2
 O
VAL C:209 C:209 68.0 0.439 E -99.6 132.3 37.0 0.239 0.2 B:P13255:0.2
 HOH
 4.327
 CG2
 O
VAL D:209 D:209 69.0 0.445 E -99.9 129.3 33.0 0.213 0.232 A:P13255:0.232
 HOH
 3.533
 CG2
 O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 VAL A:209 A:209 51.0 0.329 S -122.9 116.2 20.0 0.129 0.2 B:P13255:0.194
A:P13255:0.013
 HOH
 5.372
 CG1
 O
VAL B:209 B:209 57.0 0.368 E -113.1 124.6 25.0 0.161 0.207 A:P13255:0.206
 HOH
 3.704
 CG2
 O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 VAL A:209 A:209 69.0 0.445 E -119.0 100.6 35.0 0.226 0.219 C:P13255:0.219
VAL B:209 B:209 66.0 0.426 E -113.0 118.9 29.0 0.187 0.239 D:P13255:0.239
 CA
HOH
 8.428
3.707
 N
C
 CA
O
VAL C:209 C:209 69.0 0.445 E -112.7 102.5 34.0 0.219 0.226 A:P13255:0.226
 HOH
 8.350
 CG2
 O
VAL D:209 D:209 68.0 0.439 E -123.4 117.0 35.0 0.226 0.213 B:P13255:0.213
 HOH
 3.820
 C
 O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 VAL A:209 A:209 63.0 0.406 E -106.4 105.8 27.0 0.174 0.232 C:P13255:0.213
F:None:0.019
 C2F
 5.648
 CG2
 CG
VAL B:209 B:209 60.0 0.387 E -106.5 106.9 28.0 0.181 0.206 D:P13255:0.206
E:None:0.006
 C2F
 5.469
 CG2
 N8
VAL C:209 C:209 64.0 0.413 E -106.7 105.9 31.0 0.2 0.213 A:P13255:0.206
F:None:0.006
B:P13255:0.013
 C2F
 5.579
 CG2
 C7
VAL D:209 D:209 60.0 0.387 E -106.3 105.6 26.0 0.168 0.219 E:None:0.006
B:P13255:0.213
 C2F
HOH
 5.659
9.455
 CG2
N
 CA
O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 VAL A:210 A:209 69.0 0.445 E -117.3 124.6 30.0 0.194 0.251 C:P13255:0.226
J:None:0.032
 C2F
HOH
 5.496
2.647
 CG2
O
 CG
O
VAL B:210 B:209 68.0 0.439 E -124.3 116.5 33.0 0.213 0.226 D:P13255:0.226
 C2F
HOH
 6.235
3.743
 CG2
N
 N1
O
VAL C:210 C:209 69.0 0.445 E -115.8 123.3 32.0 0.206 0.239 J:None:0.013
A:P13255:0.232
 C2F
HOH
 5.958
3.803
 CG2
N
 N1
O
VAL D:210 D:209 69.0 0.445 E -114.5 113.0 37.0 0.239 0.206 E:None:0.013
B:P13255:0.2
 C2F
HOH
 5.634
3.467
 CG2
CG2
 CA
O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 VAL A:210 A:209 62.0 0.4 E -120.2 119.3 31.0 0.2 0.2 C:P13255:0.2
 HOH
 6.559
 C
 O
VAL B:210 B:209 66.0 0.426 E -117.0 115.4 34.0 0.219 0.207 D:P13255:0.206
 HOH
 4.900
 CG1
 O
VAL C:210 C:209 66.0 0.426 E -113.0 121.9 35.0 0.226 0.2 A:P13255:0.2
 HOH
 6.347
 C
 O
VAL D:210 D:209 66.0 0.426 E -115.8 120.5 34.0 0.219 0.207 B:P13255:0.206
 BME
HOH
 5.893
3.698
 C
C
 S2
O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 VAL A:209 A:209 57.0 0.368 E -112.6 115.2 57.0 0.368 0.0 HOH
 3.958
 C
 O
VAL B:209 B:209 61.0 0.394 E -80.6 167.6 61.0 0.394 0.0 HOH
 4.013
 O
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 VAL A:209 A:209 57.0 0.368 E -96.7 113.2 29.0 0.187 0.181 B:P13255:0.181
 HOH
 4.946
 O
 O
VAL B:209 B:209 56.0 0.361 E -133.0 106.6 35.0 0.226 0.135 A:P13255:0.135
 HOH
 6.109
 CG2
 O
VAL C:209 C:209 53.0 0.342 E -103.1 115.9 26.0 0.168 0.174 D:P13255:0.174
 HOH
 3.922
 CG1
 O
VAL D:209 D:209 68.0 0.439 E -124.5 110.6 43.0 0.277 0.162 C:P13255:0.161
 HOH
 3.962
 CG1
 O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 VAL A:209 A:209 52.0 0.335 E -115.3 129.7 21.0 0.135 0.2 D:P13255:0.2
 HOH
 5.736
 N
 O
VAL B:209 B:209 51.0 0.329 E -114.2 128.8 21.0 0.135 0.194 C:P13255:0.194
 HOH
 4.161
 CG2
 O
VAL C:209 C:209 48.0 0.31 E -111.1 141.7 20.0 0.129 0.181 B:P13255:0.181
 HOH
 5.591
 O
 O
VAL D:209 D:209 47.0 0.303 E -112.1 141.8 17.0 0.11 0.193 A:P13255:0.194
 HOH
 2.419
 CG1
 O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 VAL A:209 A:209 68.0 0.439 E -114.7 128.9 37.0 0.239 0.2 B:Q9QXF8:0.2
 BME
BME
HOH
 7.200
7.482
3.179
 CG2
O
O
 O1
O1
O
VAL B:209 B:209 65.0 0.419 E -108.3 131.1 34.0 0.219 0.2 A:Q9QXF8:0.2
 BME
HOH
 7.326
4.082
 CG2
CG2
 O1
O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 VAL A:209 A:209 70.0 0.452 E -100.7 125.3 36.0 0.232 0.22 D:Q9QXF8:0.219
C:Q9QXF8:0.013
 BME
 6.690
 C
 S2
VAL B:209 B:209 70.0 0.452 E -96.8 122.4 34.0 0.219 0.233 C:Q9QXF8:0.2
D:Q9QXF8:0.077
VAL C:209 C:209 71.0 0.458 E -106.3 122.9 38.0 0.245 0.213 A:Q9QXF8:0.013
B:Q9QXF8:0.206
VAL D:209 D:209 70.0 0.452 E -100.2 130.7 40.0 0.258 0.194 A:Q9QXF8:0.194
 BME
 7.333
 O
 O1
VAL E:209 E:209 71.0 0.458 E -97.3 129.3 NA NA NA
VAL F:209 F:209 68.0 0.439 E -95.8 120.1 NA NA NA
VAL G:209 G:209 72.0 0.465 E -93.5 125.1 NA NA NA
VAL H:209 H:209 70.0 0.452 E -93.6 120.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 VAL A:212 A:212 65.0 0.419 E -119.6 121.4