Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr6 | 42931180 | . | G | A | CCDS4876.1:NM_018960.4:c.709Ggc>Agc_NP_061833.1:p.237G>S | Homo sapiens glycine N-methyltransferase (GNMT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2azt | 1 | Q14749 | 99.66 | 0.0 |
X-RAY |
2006-09-26 | GLY | A:237 | A:236 | 129.0 | 1.0 | 360.0 | 108.6 | 129.0 | 1.0 | 0.0 | |||||||
| GLY | B:237 | B:236 | 109.0 | 1.0 | 360.0 | 108.4 | 109.0 | 1.0 | 0.0 |
HOH |
7.797 |
O |
O |
||||||||||
| 1r74 | 1 | Q14749 | 100.0 | 0.0 |
X-RAY |
2004-09-21 | GLY | A:236 | A:236 | 127.0 | 1.0 | 360.0 | 86.1 | 127.0 | 1.0 | 0.0 | |||||||
| GLY | B:236 | B:236 | 106.0 | 1.0 | 360.0 | 84.7 | 106.0 | 1.0 | 0.0 | ||||||||||||||
| 1bhj | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
1999-01-06 | GLY | A:234 | A:234 | 11.0 | 0.147 | E | -105.2 | 164.3 | 11.0 | 0.147 | 0.0 |
HOH |
3.798 |
C |
O |
||
| GLY | B:234 | B:234 | 11.0 | 0.147 | E | -113.3 | 169.8 | 11.0 | 0.147 | 0.0 |
HOH |
4.347 |
CA |
O |
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| 1d2c | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
1999-10-06 | GLY | A:234 | A:234 | 13.0 | 0.173 | E | -88.0 | 172.0 | 13.0 | 0.173 | 0.0 |
HOH |
5.720 |
CA |
O |
||
| GLY | B:234 | B:234 | 14.0 | 0.187 | E | -116.2 | 168.0 | 14.0 | 0.187 | 0.0 | |||||||||||||
| 1kia | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
2003-06-10 | GLY | A:234 | A:234 | 10.0 | 0.133 | E | -126.5 | 145.5 | 10.0 | 0.133 | 0.0 |
HOH |
8.492 |
C |
O |
||
| GLY | B:234 | B:234 | 11.0 | 0.147 | E | -127.4 | 148.2 | 11.0 | 0.147 | 0.0 |
HOH |
7.172 |
C |
O |
|||||||||
| GLY | C:234 | C:234 | 11.0 | 0.147 | E | -127.2 | 146.3 | 11.0 | 0.147 | 0.0 |
HOH |
7.530 |
C |
O |
|||||||||
| GLY | D:234 | D:234 | 10.0 | 0.133 | E | -127.5 | 145.0 | 10.0 | 0.133 | 0.0 |
HOH |
6.561 |
N |
O |
|||||||||
| 1nbh | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
2003-03-04 | GLY | A:234 | A:234 | 13.0 | 0.173 | -117.0 | 143.2 | 13.0 | 0.173 | 0.0 |
HOH |
8.917 |
C |
O |
|||
| GLY | B:234 | B:234 | 14.0 | 0.187 | -118.5 | 141.7 | 14.0 | 0.187 | 0.0 |
HOH |
6.835 |
N |
O |
||||||||||
| GLY | C:234 | C:234 | 14.0 | 0.187 | -117.3 | 145.7 | 14.0 | 0.187 | 0.0 |
HOH |
3.413 |
CA |
O |
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| GLY | D:234 | D:234 | 14.0 | 0.187 | -117.3 | 143.5 | 14.0 | 0.187 | 0.0 |
HOH |
3.896 |
CA |
O |
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| 1xva | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
1997-01-27 | GLY | A:234 | A:234 | 15.0 | 0.2 | E | -109.0 | 151.2 | 15.0 | 0.2 | 0.0 | ||||||
| GLY | B:234 | B:234 | 18.0 | 0.24 | E | -101.2 | 175.6 | 18.0 | 0.24 | 0.0 | |||||||||||||
| 2idj | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
2006-12-19 | GLY | A:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLY | B:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLY | C:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLY | D:234 | D:234 | 10.0 | 0.133 | E | -84.9 | 152.6 | 10.0 | 0.133 | 0.0 |
HOH |
6.123 |
C |
O |
|||||||||
| 2idk | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
2006-12-19 | GLY | A:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLY | B:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLY | C:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLY | D:234 | D:234 | 1.0 | 0.013 | E | -113.5 | 142.4 | 1.0 | 0.013 | 0.0 | |||||||||||||
| 3thr | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
2011-11-16 | GLY | A:235 | A:234 | 28.0 | 0.373 | E | -106.8 | 179.4 | 28.0 | 0.373 | 0.0 |
HOH |
6.631 |
C |
O |
||
| GLY | B:235 | B:234 | 24.0 | 0.32 | E | -101.0 | -177.1 | 24.0 | 0.32 | 0.0 |
HOH |
8.407 |
C |
O |
|||||||||
| GLY | C:235 | C:234 | 41.0 | 0.547 | 87.6 | 97.0 | 41.0 | 0.547 | 0.0 |
HOH |
4.294 |
CA |
O |
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| GLY | D:235 | D:234 | 28.0 | 0.373 | -173.8 | 164.1 | 28.0 | 0.373 | 0.0 |
HOH |
2.646 |
C |
O |
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| 3ths | 1 | P13255 | 92.15 | 0.0 |
X-RAY |
2011-11-16 | GLY | A:235 | A:234 | 79.0 | 1.0 | 360.0 | 75.8 | 79.0 | 1.0 | 0.0 | |||||||
| GLY | B:235 | B:234 | 26.0 | 0.347 | E | -129.0 | 168.1 | 26.0 | 0.347 | 0.0 |
HOH |
7.440 |
C |
O |
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| GLY | C:235 | C:234 | 30.0 | 0.4 | -80.5 | 168.5 | 30.0 | 0.4 | 0.0 | ||||||||||||||
| GLY | D:235 | D:234 | 73.0 | 0.973 | 360.0 | -149.0 | 73.0 | 0.973 | 0.0 | ||||||||||||||
| 1d2g | 1 | P13255 | 91.81 | 0.0 |
X-RAY |
1999-10-25 | GLY | A:234 | A:234 | 13.0 | 0.173 | E | -108.4 | 173.1 | 13.0 | 0.173 | 0.0 |
HOH |
6.916 |
CA |
O |
||
| GLY | B:234 | B:234 | 14.0 | 0.187 | E | -108.4 | 176.1 | 14.0 | 0.187 | 0.0 |
HOH |
4.878 |
N |
O |
|||||||||
| 1d2h | 1 | P13255 | 91.81 | 0.0 |
X-RAY |
1999-10-25 | GLY | A:234 | A:234 | 10.0 | 0.133 | E | -102.8 | -180.0 | 10.0 | 0.133 | 0.0 |
HOH |
5.103 |
CA |
O |
||
| GLY | B:234 | B:234 | 9.0 | 0.12 | E | -114.5 | 155.0 | 9.0 | 0.12 | 0.0 |
HOH |
7.803 |
CA |
O |
|||||||||
| GLY | C:234 | C:234 | 19.0 | 0.253 | E | -90.2 | 177.5 | 19.0 | 0.253 | 0.0 |
HOH |
6.312 |
CA |
O |
|||||||||
| GLY | D:234 | D:234 | 9.0 | 0.12 | E | -97.2 | -178.9 | 9.0 | 0.12 | 0.0 |
HOH |
8.426 |
O |
O |
|||||||||
| 1nbi | 1 | P13255 | 91.81 | 0.0 |
X-RAY |
2003-03-04 | GLY | A:234 | A:234 | 37.0 | 0.493 | 134.8 | 98.4 | 37.0 | 0.493 | 0.0 |
HOH |
5.580 |
C |
O |
|||
| GLY | B:234 | B:234 | 39.0 | 0.52 | 134.6 | 98.4 | 39.0 | 0.52 | 0.0 |
HOH |
8.990 |
N |
O |
||||||||||
| GLY | C:234 | C:234 | 52.0 | 0.693 | 131.0 | 62.0 | 52.0 | 0.693 | 0.0 |
HOH |
5.731 |
O |
O |
||||||||||
| GLY | D:234 | D:234 | 53.0 | 0.707 | 131.6 | 62.2 | 53.0 | 0.707 | 0.0 |
HOH |
9.828 |
O |
O |
||||||||||
| 1r8x | 1 | Q9QXF8 | 91.5 | 0.0 |
X-RAY |
2004-09-21 | GLY | A:234 | A:234 | 66.0 | 0.88 | 360.0 | 175.8 | 66.0 | 0.88 | 0.0 | |||||||
| GLY | B:234 | B:234 | 55.0 | 0.733 | 360.0 | 134.4 | 55.0 | 0.733 | 0.0 | ||||||||||||||
| 1r8y | 1 | Q9QXF8 | 91.5 | 0.0 |
X-RAY |
2004-09-21 | GLY | A:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLY | B:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLY | C:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLY | D:234 | D:234 | 26.0 | 0.347 | E | -93.0 | 140.1 | 26.0 | 0.347 | 0.0 | |||||||||||||
| GLY | E:234 | E:234 | 54.0 | 0.72 | 360.0 | 138.5 | NA | NA | NA | ||||||||||||||
| GLY | F:234 | F:234 | 96.0 | 1.0 | 360.0 | -122.4 | NA | NA | NA | ||||||||||||||
| GLY | G:234 | G:234 | 62.0 | 0.827 | 360.0 | 56.3 | NA | NA | NA | ||||||||||||||
| GLY | H:234 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q14749-f1 | 1 | Q14749 | 100.0 | 0.0 | GLY | A:237 | A:237 | 14.0 | 0.187 | E | -79.5 | 163.6 | |