Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 42931280 . C A CCDS4876.1:NM_018960.4:c.724Cgg>Agg_NP_061833.1:p.242R>R Homo sapiens glycine N-methyltransferase (GNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2azt 1 Q14749 99.66 0.0 X-RAY
 2006-09-26 ARG A:242 A:241 160.0 0.711 E -121.1 142.7 35.0 0.156 0.555 B:Q14749:0.556
 CIT
 8.955
 O
 O1
ARG B:242 B:241 159.0 0.707 E -118.8 140.0 62.0 0.276 0.431 A:Q14749:0.431
 CIT
HOH
 7.940
4.777
 O
NH2
 O1
O
1r74 1 Q14749 100.0 0.0 X-RAY
 2004-09-21 ARG A:241 A:241 159.0 0.707 E -141.5 138.8 58.0 0.258 0.449 B:Q14749:0.449
 CIT
 8.500
 C
 O1
ARG B:241 B:241 161.0 0.716 E -133.1 137.4 62.0 0.276 0.44 A:Q14749:0.44
 CIT
HOH
 8.346
4.552
 O
NH1
 O1
O
1bhj 1 P13255 92.15 0.0 X-RAY
 1999-01-06 ARG A:239 A:239 158.0 0.702 E -132.6 149.3 47.0 0.209 0.493 B:P13255:0.493
 HOH
 3.979
 NH2
 O
ARG B:239 B:239 161.0 0.716 E -135.6 137.0 42.0 0.187 0.529 A:P13255:0.529
 HOH
 3.061
 NH1
 O
1d2c 1 P13255 92.15 0.0 X-RAY
 1999-10-06 ARG A:239 A:239 144.0 0.64 E -130.1 154.3 35.0 0.156 0.484 B:P13255:0.484
 HOH
 3.103
 NH1
 O
ARG B:239 B:239 147.0 0.653 E -129.6 148.2 29.0 0.129 0.524 A:P13255:0.524
 HOH
 3.464
 NH1
 O
1kia 1 P13255 92.15 0.0 X-RAY
 2003-06-10 ARG A:239 A:239 142.0 0.631 E -128.4 141.6 142.0 0.631 0.0 ACT
SAM
HOH
 8.793
9.935
4.026
 C
O
N
 CH3
CE
O
ARG B:239 B:239 139.0 0.618 E -128.9 142.4 139.0 0.618 0.0 ACT
HOH
 9.081
3.234
 C
O
 OXT
O
ARG C:239 C:239 137.0 0.609 E -127.7 141.2 137.0 0.609 0.0 ACT
HOH
 8.810
3.955
 C
NH2
 CH3
O
ARG D:239 D:239 138.0 0.613 E -128.4 141.2 138.0 0.613 0.0 ACT
HOH
 8.761
3.608
 C
N
 OXT
O
1nbh 1 P13255 92.15 0.0 X-RAY
 2003-03-04 ARG A:239 A:239 139.0 0.618 E -127.8 144.6 139.0 0.618 0.0 ACT
HOH
 8.820
3.440
 C
O
 CH3
O
ARG B:239 B:239 140.0 0.622 E -128.4 143.4 140.0 0.622 0.0 ACT
HOH
 8.870
3.413
 C
NH2
 CH3
O
ARG C:239 C:239 140.0 0.622 E -128.6 144.3 140.0 0.622 0.0 ACT
HOH
 8.867
3.362
 C
NH2
 CH3
O
ARG D:239 D:239 139.0 0.618 E -128.6 143.4 139.0 0.618 0.0 ACT
HOH
 8.845
3.778
 C
NH1
 CH3
O
1xva 1 P13255 92.15 0.0 X-RAY
 1997-01-27 ARG A:239 A:239 151.0 0.671 E -136.4 151.1 43.0 0.191 0.48 B:P13255:0.48
 ACT
SAM
HOH
 7.467
9.178
3.865
 O
C
NH2
 O
O2'
O
ARG B:239 B:239 151.0 0.671 E -134.2 149.6 32.0 0.142 0.529 A:P13255:0.529
 ACT
SAM
HOH
 7.324
8.618
3.726
 O
C
NH1
 O
O2'
O
2idj 1 P13255 92.15 0.0 X-RAY
 2006-12-19 ARG A:239 A:239 143.0 0.636 E -130.9 156.5 35.0 0.156 0.48 B:P13255:0.48
ARG B:239 B:239 153.0 0.68 E -124.1 141.5 58.0 0.258 0.422 A:P13255:0.422
 HOH
 3.907
 NH1
 O
ARG C:239 C:239 153.0 0.68 E -140.6 152.1 40.0 0.178 0.502 D:P13255:0.502
ARG D:239 D:239 154.0 0.684 E -121.9 143.8 60.0 0.267 0.417 C:P13255:0.418
 HOH
 4.510
 NH2
 O
2idk 1 P13255 92.15 0.0 X-RAY
 2006-12-19 ARG A:239 A:239 148.0 0.658 E -142.5 159.9 38.0 0.169 0.489 F:None:0.04
B:P13255:0.48
 C2F
 5.817
 NH2
 C7
ARG B:239 B:239 146.0 0.649 E -132.9 153.7 28.0 0.124 0.525 E:None:0.187
A:P13255:0.436
 C2F
 2.919
 NH1
 C13
ARG C:239 C:239 146.0 0.649 E -139.0 152.5 17.0 0.076 0.573 D:P13255:0.449
F:None:0.213
 C2F
HOH
 3.266
9.938
 NH1
O
 C13
O
ARG D:239 D:239 142.0 0.631 E -133.0 154.4 35.0 0.156 0.475 E:None:0.018
C:P13255:0.476
 C2F
HOH
 6.055
3.404
 NH2
NH1
 C7
O
3thr 1 P13255 92.15 0.0 X-RAY
 2011-11-16 ARG A:240 A:239 151.0 0.671 E -122.4 136.0 36.0 0.16 0.511 J:None:0.053
B:P13255:0.498
 TAM
C2F
HOH
 7.520
5.663
3.505
 O
NH2
NH1
 O5
N8
O
ARG B:240 B:239 147.0 0.653 E -129.2 135.9 25.0 0.111 0.542 E:None:0.204
A:P13255:0.453
 C2F
HOH
 2.805
3.210
 NH2
NH2
 O
O
ARG C:240 C:239 150.0 0.667 E -127.8 143.8 25.0 0.111 0.556 D:P13255:0.467
J:None:0.204
 TAM
C2F
HOH
 7.614
2.795
3.631
 O
NH2
NH1
 O6
O
O
ARG D:240 D:239 150.0 0.667 E -131.2 134.5 38.0 0.169 0.498 C:P13255:0.493
E:None:0.044
 C2F
TAM
HOH
 5.798
9.919
3.062
 NH2
O
NH2
 N8
O6
O
3ths 1 P13255 92.15 0.0 X-RAY
 2011-11-16 ARG A:240 A:239 149.0 0.662 E -144.9 133.5 33.0 0.147 0.515 B:P13255:0.516
 HOH
 2.751
 NH2
 O
ARG B:240 B:239 143.0 0.636 E -127.2 143.7 41.0 0.182 0.454 A:P13255:0.453
 TAM
HOH
 8.108
4.404
 C
NH2
 O4
O
ARG C:240 C:239 148.0 0.658 E -148.8 140.3 47.0 0.209 0.449 D:P13255:0.449
ARG D:240 D:239 147.0 0.653 E -134.8 136.5 39.0 0.173 0.48 C:P13255:0.48
 HOH
 3.424
 NH1
 O
1d2g 1 P13255 91.81 0.0 X-RAY
 1999-10-25 ARG A:239 A:239 148.0 0.658 E -133.9 146.8 39.0 0.173 0.485 B:P13255:0.484
 HOH
 3.187
 NH1
 O
ARG B:239 B:239 149.0 0.662 E -127.1 145.3 38.0 0.169 0.493 A:P13255:0.493
 HOH
 3.751
 CZ
 O
1d2h 1 P13255 91.81 0.0 X-RAY
 1999-10-25 ARG A:239 A:239 149.0 0.662 E -149.4 124.2 149.0 0.662 0.0 SAH
HOH
 9.330
2.742
 C
NH2
 OXT
O
ARG B:239 B:239 139.0 0.618 E -134.1 161.7 139.0 0.618 0.0 HOH
 6.207
 NH2
 O
ARG C:239 C:239 149.0 0.662 E -98.0 148.1 149.0 0.662 0.0 HOH
 2.891
 NH1
 O
ARG D:239 D:239 133.0 0.591 E -102.2 145.1 133.0 0.591 0.0 HOH
 7.085
 CD
 O
1nbi 1 P13255 91.81 0.0 X-RAY
 2003-03-04 ARG A:239 A:239 138.0 0.613 E -147.5 134.6 138.0 0.613 0.0 HOH
 3.955
 CD
 O
ARG B:239 B:239 135.0 0.6 E -146.9 134.4 135.0 0.6 0.0 HOH
 2.874
 NH2
 O
ARG C:239 C:239 158.0 0.702 E -129.8 151.1 158.0 0.702 0.0 HOH
 3.240
 NH1
 O
ARG D:239 D:239 158.0 0.702 E -132.9 151.6 158.0 0.702 0.0 HOH
 3.146
 NE
 O
1r8x 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 ARG A:239 A:239 144.0 0.64 E -139.2 140.2 38.0 0.169 0.471 B:Q9QXF8:0.471
 BME
HOH
 9.098
3.597
 NH2
NH2
 O1
O
ARG B:239 B:239 151.0 0.671 E -133.0 136.9 40.0 0.178 0.493 A:Q9QXF8:0.493
 BME
HOH
 8.723
3.600
 NH2
CD
 O1
O
1r8y 1 Q9QXF8 91.5 0.0 X-RAY
 2004-09-21 ARG A:239 A:239 153.0 0.68 E -133.7 147.3 51.0 0.227 0.453 B:Q9QXF8:0.453
ARG B:239 B:239 149.0 0.662 E -135.5 142.3 40.0 0.178 0.484 A:Q9QXF8:0.484
ARG C:239 C:239 148.0 0.658 E -135.3 142.7 29.0 0.129 0.529 D:Q9QXF8:0.529
ARG D:239 D:239 153.0 0.68 E -128.7 143.4 37.0 0.164 0.516 C:Q9QXF8:0.516
 HOH
 9.811
 O
 O
ARG E:239 E:239 150.0 0.667 E -139.1 142.4 NA NA NA
ARG F:239 F:239 150.0 0.667 E -132.6 147.9 NA NA NA
ARG G:239 G:239 152.0 0.676 E -136.7 139.5 NA NA NA
ARG H:239 H:239 136.0 0.604 E -133.8 142.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14749-f1 1 Q14749 100.0 0.0 ARG A:242 A:242 54.0 0.24 E -119.5 132.2