Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52053864 . A C CCDS4937.1:NM_002190.2:c.242gAc>gCc_NP_002181.1:p.81D>A Homo sapiens interleukin 17A (IL17A), mRNA.
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5n7w 3 Q16552 100.0 2e-113 X-RAY
 2018-11-14 ASP E:81 X:58 36.0 0.24 -135.3 109.4 36.0 0.24 0.0 HOH
 3.954
 O
 O
ASP F:81 Y:58 36.0 0.24 -135.0 111.5 36.0 0.24 0.0 HOH
 2.805
 OD1
 O
6wio 3 Q16552 100.0 3e-113 X-RAY
 2020-09-23 ASP C:81 C:81 59.0 0.393 -149.1 137.4 59.0 0.393 0.0
6wir 3 Q16552 100.0 3e-113 X-RAY
 2020-09-23 ASP C:81 C:58 71.0 0.473 -69.5 145.7 71.0 0.473 0.0
2vxs 1 Q16552 100.0 1e-99 X-RAY
 2009-07-14 ASP A:63 A:58 67.0 0.447 -139.0 111.1 NA NA NA
ASP B:63 B:58 123.0 0.82 -140.2 360.0 NA NA NA
ASP C:63 C:58 137.0 0.913 -166.5 360.0 137.0 0.913 0.0
ASP D:63 D:58 67.0 0.447 -135.3 110.7 67.0 0.447 0.0
5hhx 1 Q16552 98.55 2e-99 X-RAY
 2016-06-01 ASP A:64 A:58 42.0 0.28 -167.0 116.1 42.0 0.28 0.0 HOH
 5.420
 OD2
 O
ASP B:64 NA:NA DO NA DO DO DO NA NA NA
5hi3 1 Q16552 100.0 1e-96 X-RAY
 2016-08-31 ASP A:58 A:58 40.0 0.267 -157.7 103.3 40.0 0.267 0.0
ASP B:58 B:58 40.0 0.267 -156.5 103.0 40.0 0.267 0.0
5hi4 1 Q16552 100.0 1e-96 X-RAY
 2016-08-31 ASP A:58 A:58 39.0 0.26 -153.8 109.2 39.0 0.26 0.0
ASP B:58 B:58 37.0 0.247 -154.4 109.1 37.0 0.247 0.0 63P
 9.601
 CB
 H36
5hi5 1 Q16552 100.0 1e-96 X-RAY
 2016-08-31 ASP A:58 A:58 35.0 0.233 -155.8 108.8 35.0 0.233 0.0 63Q
 9.466
 CB
 H30
ASP B:58 B:58 36.0 0.24 -155.0 108.9 36.0 0.24 0.0 63Q
 9.802
 O
 H11
5n92 1 Q16552 100.0 1e-96 X-RAY
 2017-09-06 ASP A:58 A:81 34.0 0.227 -146.5 106.1 34.0 0.227 0.0 HOH
 4.947
 OD2
 O
5nan 1 Q16552 100.0 1e-96 X-RAY
 2017-09-06 ASP A:58 A:81 32.0 0.213 -151.4 111.2 32.0 0.213 0.0
ASP D:58 D:81 32.0 0.213 -151.2 110.9 NA NA NA
4qhu 3 Q16552 98.48 2e-95 X-RAY
 2015-08-05 ASP E:58 C:58 30.0 0.2 -147.5 109.0 23.0 0.153 0.047 B:None:0.047
 HOH
 2.507
 OD2
 O
ASP F:58 D:58 31.0 0.207 -146.1 111.4 23.0 0.153 0.054 D:None:0.053
 GOL
HOH
 6.384
2.638
 N
OD2
 O3
O
5hhv 1 Q16552 98.36 5e-87 X-RAY
 2016-06-01 ASP A:49 A:58 40.0 0.267 -149.0 107.8 40.0 0.267 0.0
ASP B:49 NA:NA DO NA DO DO DO NA NA NA
4hr9 1 Q16552 98.36 6e-87 X-RAY
 2013-05-22 ASP A:48 A:58 36.0 0.24 -143.7 110.1 36.0 0.24 0.0 HOH
 6.703
 O
 O
ASP B:48 B:58 39.0 0.26 -142.1 109.9 39.0 0.26 0.0 HOH
 2.776
 OD2
 O
4hsa 1 Q16552 98.36 6e-87 X-RAY
 2013-05-22 ASP A:48 A:58 36.0 0.24 -156.7 108.3 36.0 0.24 0.0
ASP B:48 B:58 38.0 0.253 -150.2 109.5 38.0 0.253 0.0 HOH
 6.118
 O
 O
ASP D:48 D:58 36.0 0.24 -154.3 107.7 NA NA NA
ASP E:48 E:58 43.0 0.287 -143.2 109.3 NA NA NA
5vb9 1 Q16552 98.31 6e-84 X-RAY
 2018-02-14 ASP A:45 A:58 41.0 0.273 -142.9 107.7 41.0 0.273 0.0 EDO
HOH
 9.278
2.655
 O
OD2
 O2
O
ASP B:45 B:58 41.0 0.273 -143.5 107.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16552-f1 1 Q16552 100.0 6e-114 ASP A:81 A:81 25.0 0.167 -134.6 106.5