Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52617692 . T A CCDS4944.1:NM_000846.4:c.374cAa>cTa_NP_000837.3:p.125Q>L Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2vct 1 P09210 99.55 1e-162 X-RAY
 2008-10-28 GLN A:125 A:125 60.0 0.333 H -63.0 -47.8 60.0 0.333 0.0 HOH
 3.378
 O
 O
GLN B:125 B:125 61.0 0.339 H -49.4 -55.9 61.0 0.339 0.0 HOH
 2.667
 OE1
 O
GLN C:125 C:125 66.0 0.367 H -60.2 -35.4 NA NA NA
GLN D:125 D:125 57.0 0.317 H -59.5 -51.2 NA NA NA
GLN E:125 E:125 67.0 0.372 H -59.7 -43.4 NA NA NA
GLN F:125 F:125 49.0 0.272 H -60.5 -45.0 NA NA NA
GLN G:125 G:125 51.0 0.283 H -67.3 -50.8 NA NA NA
GLN H:125 H:125 66.0 0.367 H -57.3 -46.9 NA NA NA
2wju 1 P09210 99.55 1e-162 X-RAY
 2009-06-09 GLN A:125 A:125 67.0 0.372 H -54.0 -50.8 67.0 0.372 0.0 HOH
 6.532
 NE2
 O
GLN B:125 B:125 55.0 0.306 H -62.8 -32.9 55.0 0.306 0.0 HOH
 6.210
 NE2
 O
GLN C:125 C:125 64.0 0.356 H -57.3 -54.1 NA NA NA
GLN D:125 D:125 60.0 0.333 H -54.9 -45.9 NA NA NA
GLN E:125 E:125 63.0 0.35 H -61.4 -32.6 NA NA NA
GLN F:125 F:125 57.0 0.317 H -71.6 -44.1 NA NA NA
GLN G:125 G:125 59.0 0.328 H -58.7 -47.6 NA NA NA
GLN H:125 H:125 69.0 0.383 H -52.5 -45.0 NA NA NA
4acs 1 P09210 98.64 2e-158 X-RAY
 2011-12-28 GLN A:125 A:125 56.0 0.311 H -45.9 -46.7 56.0 0.311 0.0 HOH
 2.735
 OE1
 O
GLN B:125 B:125 59.0 0.328 H -64.0 -48.4 59.0 0.328 0.0 HOH
 6.154
 NE2
 O
GLN C:125 C:125 61.0 0.339 H -63.0 -42.7 NA NA NA
GLN D:125 D:125 68.0 0.378 H -71.2 -43.6 NA NA NA
1pkw 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 LYS A:125 A:125 57.0 0.285 H -63.9 -38.3 57.0 0.285 0.0 HOH
 3.661
 CB
 O
LYS B:125 B:125 51.0 0.255 H -62.9 -35.8 51.0 0.255 0.0 HOH
 2.566
 NZ
 O
1pkz 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 LYS A:125 A:125 59.0 0.295 H -64.2 -37.0 59.0 0.295 0.0 HOH
 2.653
 NZ
 O
LYS B:125 B:125 49.0 0.245 H -60.9 -41.3 49.0 0.245 0.0 HOH
 3.579
 CB
 O
1pl1 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 LYS A:125 A:125 61.0 0.305 H -62.7 -39.4 61.0 0.305 0.0 HOH
 2.726
 NZ
 O
LYS B:125 B:125 51.0 0.255 H -62.7 -39.5 51.0 0.255 0.0 HOH
 2.673
 NZ
 O
6yaw 1 P08263 95.05 4e-154 X-RAY
 2020-08-26 LYS A:125 A:125 61.0 0.305 H -64.1 -40.8 61.0 0.305 0.0 HOH
 9.714
 O
 O
LYS B:125 B:125 57.0 0.285 H -66.0 -41.9 57.0 0.285 0.0 HOH
 5.755
 CD
 O
2r6k 1 P08263 94.59 5e-154 X-RAY
 2008-08-19 LYS A:125 A:125 58.0 0.29 H -58.9 -42.8 58.0 0.29 0.0 HOH
 3.768
 NZ
 O
LYS B:125 B:125 59.0 0.295 H -70.2 -37.6 59.0 0.295 0.0 HOH
 4.810
 NZ
 O
3zfl 1 P08263 94.59 1e-153 X-RAY
 2012-12-19 LYS A:125 A:125 50.0 0.25 H -63.1 -37.1 50.0 0.25 0.0 HOH
 7.478
 NZ
 O
LYS B:125 B:125 48.0 0.24 H -62.8 -43.0 48.0 0.24 0.0 HOH
 3.318
 NZ
 O
3zfb 1 P08263 94.59 2e-153 X-RAY
 2012-12-19 LYS A:125 A:125 62.0 0.31 H -59.2 -27.8 62.0 0.31 0.0 HOH
 2.791
 NZ
 O
LYS B:125 B:125 51.0 0.255 H -60.2 -40.4 51.0 0.255 0.0 HOH
 4.122
 CB
 O
1ydk 1 P08263 94.59 2e-153 X-RAY
 2005-06-07 LYS A:125 A:125 51.0 0.255 H -64.1 -37.9 51.0 0.255 0.0 HOH
 4.155
 CB
 O
LYS B:125 B:125 51.0 0.255 H -63.1 -42.9 51.0 0.255 0.0 HOH
 3.688
 CD
 O
3u6v 1 P08263 94.59 2e-153 X-RAY
 2011-10-26 LYS A:125 A:125 58.0 0.29 H -61.7 -43.4 58.0 0.29 0.0 HOH
 3.492
 NZ
 O
LYS B:125 B:125 67.0 0.335 H -69.7 -42.0 67.0 0.335 0.0 HOH
 3.530
 CD
 O
1gsd 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 LYS A:124 A:125 60.0 0.3 H -65.9 -36.2 60.0 0.3 0.0 HOH
 8.089
 C
 O
LYS B:124 B:125 58.0 0.29 H -66.0 -36.2 58.0 0.29 0.0 HOH
 8.089
 C
 O
LYS C:124 C:125 59.0 0.295 H -66.0 -36.1 NA NA NA
LYS D:124 D:125 58.0 0.29 H -66.0 -36.2 NA NA NA
1gsf 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 LYS A:124 A:125 66.0 0.33 H -72.1 -25.5 66.0 0.33 0.0
LYS B:124 B:125 65.0 0.325 H -72.2 -25.5 65.0 0.325 0.0
LYS C:124 C:125 65.0 0.325 H -72.2 -25.5 NA NA NA
LYS D:124 D:125 64.0 0.32 H -72.2 -25.5 NA NA NA
1guh 1 P08263 95.02 2e-153 X-RAY
 1993-10-31 LYS A:124 A:125 61.0 0.305 H -68.7 -29.5 61.0 0.305 0.0
LYS B:124 B:125 62.0 0.31 H -68.7 -29.5 62.0 0.31 0.0
LYS C:124 C:125 62.0 0.31 H -68.6 -29.5 NA NA NA
LYS D:124 D:125 60.0 0.3 H -68.7 -29.4 NA NA NA
1k3l 1 P08263 95.02 2e-153 X-RAY
 2002-10-23 LYS A:124 A:125 52.0 0.26 H -61.4 -38.5 52.0 0.26 0.0 HOH
 3.312
 CB
 O
LYS B:124 B:125 55.0 0.275 H -60.8 -38.9 55.0 0.275 0.0 HOH
 2.944
 NZ
 O
1k3o 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 LYS A:124 A:125 58.0 0.29 H -82.8 -34.1 58.0 0.29 0.0 HOH
 8.632
 O
 O
LYS B:124 B:125 65.0 0.325 H -83.7 -29.9 65.0 0.325 0.0 HOH
 3.107
 NZ
 O
1k3y 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 LYS A:124 A:125 63.0 0.315 H -68.2 -38.6 63.0 0.315 0.0 HOH
 4.225
 CB
 O
LYS B:124 B:125 63.0 0.315 H -63.3 -39.3 63.0 0.315 0.0 HOH
 3.073
 NZ
 O
6ato 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 LYS A:124 A:125 55.0 0.275 H -65.5 -38.2 55.0 0.275 0.0 HOH
 2.753
 NZ
 O
LYS B:124 B:125 73.0 0.365 H -65.7 -41.1 NA NA NA
6atp 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 LYS A:124 A:125 53.0 0.265 H -65.8 -36.1 53.0 0.265 0.0 HOH
 3.048
 NZ
 O
LYS B:124 B:125 61.0 0.305 H -63.2 -40.8 NA NA NA
6atq 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 LYS A:124 A:125 57.0 0.285 H -58.0 -35.1 57.0 0.285 0.0 HOH
 4.190
 CB
 O
LYS B:124 B:125 60.0 0.3 H -66.4 -41.5 NA NA NA
6atr 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 LYS A:124 A:125 62.0 0.31 H -62.8 -39.2 62.0 0.31 0.0 EDO
HOH
 8.789
2.377
 CE
NZ
 H21
O
LYS B:124 B:125 61.0 0.305 H -64.7 -38.1 NA NA NA
1pl2 1 P08263 94.59 4e-153 X-RAY
 2004-06-22 LYS A:125 A:125 64.0 0.32 H -61.8 -38.1 64.0 0.32 0.0 HOH
 2.595
 NZ
 O
LYS B:125 B:125 64.0 0.32 H -64.2 -38.7 64.0 0.32 0.0 HOH
 2.464
 NZ
 O
1usb 1 P08263 95.02 5e-153 X-RAY
 2004-09-01 LYS A:128 A:125 65.0 0.325 H -44.1 -43.3 65.0 0.325 0.0 HOH
 8.139
 O
 O
LYS B:128 B:125 68.0 0.34 H -72.1 -35.7 68.0 0.34 0.0 HOH
 3.698
 CE
 O
2r3x 1 P08263 94.59 6e-153 X-RAY
 2007-12-18 LYS A:125 A:125 55.0 0.275 H -66.1 -42.1 55.0 0.275 0.0 HOH
 3.242
 NZ
 O
LYS B:125 B:125 56.0 0.28 H -53.4 -46.7 56.0 0.28 0.0 HOH
 3.148
 NZ
 O
5jcu 1 P08263 95.02 8e-153 X-RAY
 2016-10-12 LYS A:124 A:125 60.0 0.3 H -60.8 -40.3 60.0 0.3 0.0 EDO
HOH
 9.833
3.627
 CE
CD
 C1
O
LYS B:124 B:125 63.0 0.315 H -66.9 -41.9 63.0 0.315 0.0 HOH
 3.332
 CD
 O
LYS C:124 C:125 65.0 0.325 H -60.4 -44.0 NA NA NA
LYS D:124 D:125 65.0 0.325 H -61.7 -38.3 NA NA NA
1gse 1 P08263 94.57 9e-153 X-RAY
 1995-09-15 LYS A:124 A:125 55.0 0.275 H -58.2 -33.3 55.0 0.275 0.0 HOH
 4.479
 CB
 O
LYS B:124 B:125 56.0 0.28 H -63.0 -35.3 56.0 0.28 0.0 HOH
 4.072
 CB
 O
3ktl 1 P08263 94.57 1e-152 X-RAY
 2009-12-22 LYS A:124 A:125 49.0 0.245 H -64.6 -36.4 49.0 0.245 0.0 HOH
 2.756
 NZ
 O
LYS B:124 B:125 64.0 0.32 H -65.0 -33.9 64.0 0.32 0.0 HOH
 2.257
 NZ
 O
3q74 1 P08263 94.57 1e-152 X-RAY
 2011-01-12 LYS A:124 A:125 46.0 0.23 H -61.2 -38.4 46.0 0.23 0.0 HOH
 3.310
 NZ
 O
LYS B:124 B:125 50.0 0.25 H -60.8 -39.7 50.0 0.25 0.0 HOH
 3.697
 CB
 O
3l0h 1 P08263 94.59 2e-152 X-RAY
 2010-01-12 LYS A:125 A:125 58.0 0.29 H -63.5 -43.2 58.0 0.29 0.0 HOH
 3.764
 CD
 O
LYS B:125 B:125 60.0 0.3 H -68.5 -45.4 60.0 0.3 0.0 HOH
 3.393
 NZ
 O
1xwg 1 P08263 94.57 5e-152 X-RAY
 2005-11-01 LYS A:124 A:125 60.0 0.3 H -66.6 -35.5 60.0 0.3 0.0 HOH
 2.754
 NZ
 O
LYS B:124 B:125 52.0 0.26 H -63.6 -37.4 52.0 0.26 0.0 HOH
 3.342
 CE
 O
4hj2 1 P08263 94.93 4e-150 X-RAY
 2013-03-27 LYS A:122 A:125 62.0 0.31 H -66.6 -32.5 62.0 0.31 0.0 HOH
 3.627
 CD
 O
LYS B:122 B:125 62.0 0.31 H -60.1 -40.4 62.0 0.31 0.0 HOH
 4.645
 O
 O
3i69 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 LYS A:125 A:125 60.0 0.3 H -55.4 -38.9 60.0 0.3 0.0 HOH
 3.937
 CB
 O
LYS B:125 B:125 61.0 0.305 H -65.2 -52.0 61.0 0.305 0.0 HOH
 9.053
 O
 O
LYS C:125 C:125 62.0 0.31 H -56.4 -36.7 NA NA NA
LYS D:125 D:125 56.0 0.28 H -61.6 -49.2 NA NA NA
LYS E:125 E:125 68.0 0.34 H -62.6 -41.9 NA NA NA
LYS F:125 F:125 59.0 0.295 H -53.4 -47.1 NA NA NA
LYS G:125 G:125 68.0 0.34 H -63.5 -40.3 NA NA NA
LYS H:125 H:125 65.0 0.325 H -62.3 -45.7 NA NA NA
3i6a 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 LYS A:125 A:125 59.0 0.295 H -62.8 -39.2 59.0 0.295 0.0 HOH
 3.872
 CB
 O
LYS B:125 B:125 66.0 0.33 H -60.3 -43.9 66.0 0.33 0.0 HOH
 8.665
 O
 O
LYS C:125 C:125 67.0 0.335 H -54.7 -43.1 NA NA NA
LYS D:125 D:125 68.0 0.34 H -60.1 -43.6 NA NA NA
LYS E:125 E:125 68.0 0.34 H -61.9 -42.4 NA NA NA
LYS F:125 F:125 59.0 0.295 H -61.5 -44.0 NA NA NA
LYS G:125 G:125 62.0 0.31 H -64.0 -37.6 NA NA NA
LYS H:125 H:125 68.0 0.34 H -63.8 -41.8 NA NA NA
3ik9 1 P08263 90.95 3e-145 X-RAY
 2010-06-23 LYS A:125 A:125 62.0 0.31 H -47.6 -46.6 62.0 0.31 0.0
LYS B:125 B:125 62.0 0.31 H -63.1 -48.0 62.0 0.31 0.0
LYS C:125 C:125 70.0 0.35 H -58.7 -42.0 NA NA NA
LYS D:125 D:125 66.0 0.33 H -66.5 -49.4 NA NA NA
LYS E:125 E:125 64.0 0.32 H -68.1 -48.6 NA NA NA
LYS F:125 F:125 51.0 0.255 H -56.7 -45.2 NA NA NA
LYS G:125 G:125 64.0 0.32 H -68.0 -38.9 NA NA NA
LYS H:125 H:125 70.0 0.35 H -57.7 -41.4 NA NA NA
1tdi 1 Q16772 88.74 4e-143 X-RAY
 2005-01-18 LYS A:125 A:125 62.0 0.31 H -63.8 -45.7 62.0 0.31 0.0 HOH
 3.545
 CD
 O
LYS B:125 B:125 59.0 0.295 H -54.3 -46.3 59.0 0.295 0.0 HOH
 4.034
 CB
 O
2vcv 1 Q16772 88.74 4e-143 X-RAY
 2008-10-28 LYS A:125 A:125 64.0 0.32 H -56.8 -47.8 64.0 0.32 0.0 HOH
 3.201
 NZ
 O
LYS B:125 B:125 65.0 0.325 H -63.0 -45.0 65.0 0.325 0.0 HOH
 3.586
 CB
 O
LYS C:125 C:125 64.0 0.32 H -59.5 -24.9 NA NA NA
LYS D:125 D:125 66.0 0.33 H -57.1 -48.5 NA NA NA
LYS E:125 E:125 65.0 0.325 H -52.1 -44.2 NA NA NA
LYS F:125 F:125 68.0 0.34 H -62.7 -42.6 NA NA NA
LYS G:125 G:125 67.0 0.335 H -55.0 -44.1 NA NA NA
LYS H:125 H:125 65.0 0.325 H -58.0 -42.3 NA NA NA
LYS I:125 I:125 67.0 0.335 H -57.8 -50.5 NA NA NA
LYS J:125 J:125 62.0 0.31 H -62.2 -38.4 NA NA NA
LYS K:125 K:125 65.0 0.325 H -63.5 -45.4 NA NA NA
LYS L:125 L:125 66.0 0.33 H -56.8 -44.4 NA NA NA
LYS M:125 M:125 68.0 0.34 H -55.6 -46.8 NA NA NA
LYS N:125 N:125 66.0 0.33 H -59.1 -41.5 NA NA NA
LYS O:125 O:125 64.0 0.32 H -60.0 -46.4 NA NA NA
LYS P:125 P:125 70.0 0.35 H -59.6 -40.6 NA NA NA
5lcz 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 LYS A:125 A:125 78.0 0.39 H -57.0 -41.9 78.0 0.39 0.0 HOH
 3.534
 N
 O
LYS B:125 B:125 47.0 0.235 H -59.4 -43.7 47.0 0.235 0.0 HOH
 8.010
 NZ
 O
5ld0 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 LYS A:125 A:125 68.0 0.34 H -65.7 -41.3 68.0 0.34 0.0 HOH
 3.635
 CD
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09210-f1 1 P09210 100.0 3e-163 GLN A:125 A:125 55.0 0.306 H -62.6 -44.7
af-p08263-f1 1 P08263 95.05 1e-154 LYS A:125 A:125 58.0 0.29 H -63.1 -37.3
af-q7rtv2-f1 1 Q7RTV2 88.74 1e-143 LYS A:125 A:125 56.0 0.28 H -61.0 -40.0
af-q16772-f1 1 Q16772 88.74 2e-143 LYS A:125 A:125 59.0 0.295 H -61.7 -43.7