Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52617723 . C A CCDS4944.1:NM_000846.4:c.343Gag>Tag_NP_000837.3:p.115E>* Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2vct 1 P09210 99.55 1e-162 X-RAY
 2008-10-28 GLU A:115 A:115 144.0 0.758 T -77.7 -13.8 144.0 0.758 0.0 HOH
 2.577
 O
 O
GLU B:115 B:115 151.0 0.795 T -87.2 26.2 151.0 0.795 0.0 HOH
 3.708
 C
 O
GLU C:115 C:115 184.0 0.968 G -81.4 4.6 NA NA NA
GLU D:115 D:115 151.0 0.795 T -75.9 -16.9 NA NA NA
GLU E:115 E:115 131.0 0.689 T -73.7 -54.4 NA NA NA
GLU F:115 F:115 150.0 0.789 T -89.2 -3.4 NA NA NA
GLU G:115 G:115 142.0 0.747 T -80.2 -21.8 NA NA NA
GLU H:115 H:115 131.0 0.689 T -80.0 -25.2 NA NA NA
2wju 1 P09210 99.55 1e-162 X-RAY
 2009-06-09 GLU A:115 A:115 137.0 0.721 T -71.2 -58.6 137.0 0.721 0.0
GLU B:115 B:115 133.0 0.7 T -98.2 -33.1 133.0 0.7 0.0
GLU C:115 C:115 146.0 0.768 T -74.0 -38.1 NA NA NA
GLU D:115 D:115 128.0 0.674 T -84.3 -23.2 NA NA NA
GLU E:115 E:115 117.0 0.616 T -84.3 -42.3 NA NA NA
GLU F:115 F:115 121.0 0.637 T -46.3 -68.0 NA NA NA
GLU G:115 G:115 140.0 0.737 T -60.6 -56.5 NA NA NA
GLU H:115 H:115 148.0 0.779 T -53.9 -55.9 NA NA NA
4acs 1 P09210 98.64 2e-158 X-RAY
 2011-12-28 GLU A:115 A:115 137.0 0.721 T -67.8 -42.4 137.0 0.721 0.0 HOH
 3.095
 O
 O
GLU B:115 B:115 149.0 0.784 H -53.7 -24.4 149.0 0.784 0.0 HOH
 3.668
 O
 O
GLU C:115 C:115 138.0 0.726 H -64.8 -37.9 NA NA NA
GLU D:115 D:115 148.0 0.779 G -55.7 -40.1 NA NA NA
1pkw 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 GLU A:115 A:115 201.0 1.0 T -88.4 -7.7 201.0 1.0 0.0 HOH
 2.899
 OE1
 O
GLU B:115 B:115 152.0 0.8 G -63.0 -23.1 152.0 0.8 0.0 HOH
 2.431
 OE2
 O
1pkz 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 GLU A:115 A:115 159.0 0.837 T -82.7 -1.2 159.0 0.837 0.0
GLU B:115 B:115 160.0 0.842 G -70.0 -19.3 160.0 0.842 0.0 HOH
 2.920
 O
 O
1pl1 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 GLU A:115 A:115 149.0 0.784 H -77.1 -7.8 149.0 0.784 0.0 HOH
 2.926
 O
 O
GLU B:115 B:115 152.0 0.8 G -72.9 -16.5 152.0 0.8 0.0 HOH
 2.462
 OE2
 O
6yaw 1 P08263 95.05 4e-154 X-RAY
 2020-08-26 GLU A:115 A:115 172.0 0.905 T -56.5 -34.3 172.0 0.905 0.0
GLU B:115 B:115 150.0 0.789 G -73.4 -19.0 150.0 0.789 0.0 HOH
 3.222
 O
 O
2r6k 1 P08263 94.59 5e-154 X-RAY
 2008-08-19 GLU A:115 A:115 183.0 0.963 T -79.2 -24.1 183.0 0.963 0.0 HOH
 3.025
 O
 O
GLU B:115 B:115 152.0 0.8 T -76.3 -19.8 152.0 0.8 0.0 HOH
 3.318
 O
 O
3zfl 1 P08263 94.59 1e-153 X-RAY
 2012-12-19 GLU A:115 A:115 187.0 0.984 H -49.7 -55.0 187.0 0.984 0.0 HOH
 6.949
 N
 O
GLU B:115 B:115 152.0 0.8 H -68.7 -14.5 152.0 0.8 0.0 HOH
 2.377
 OE1
 O
3zfb 1 P08263 94.59 2e-153 X-RAY
 2012-12-19 GLU A:115 A:115 192.0 1.0 H -69.4 -17.6 192.0 1.0 0.0 HOH
 2.804
 OE1
 O
GLU B:115 B:115 155.0 0.816 G -77.7 -14.6 155.0 0.816 0.0 HOH
 2.443
 OE1
 O
1ydk 1 P08263 94.59 2e-153 X-RAY
 2005-06-07 GLU A:115 A:115 156.0 0.821 T -73.6 -19.6 156.0 0.821 0.0 HOH
 2.746
 O
 O
GLU B:115 B:115 149.0 0.784 G -74.7 -11.7 149.0 0.784 0.0 HOH
 2.723
 O
 O
3u6v 1 P08263 94.59 2e-153 X-RAY
 2011-10-26 GLU A:115 A:115 178.0 0.937 T -71.6 -44.8 178.0 0.937 0.0 HOH
 5.525
 C
 O
GLU B:115 B:115 152.0 0.8 T -76.9 -14.0 152.0 0.8 0.0 HOH
 2.458
 OE1
 O
1gsd 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 GLU A:114 A:115 141.0 0.742 T -71.0 -32.1 141.0 0.742 0.0
GLU B:114 B:115 138.0 0.726 T -71.0 -32.2 138.0 0.726 0.0
GLU C:114 C:115 139.0 0.732 T -71.1 -32.1 NA NA NA
GLU D:114 D:115 137.0 0.721 T -71.0 -32.2 NA NA NA
1gsf 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 GLU A:114 A:115 148.0 0.779 T -72.2 -30.5 148.0 0.779 0.0
GLU B:114 B:115 148.0 0.779 T -72.2 -30.5 148.0 0.779 0.0
GLU C:114 C:115 147.0 0.774 T -72.2 -30.4 NA NA NA
GLU D:114 D:115 147.0 0.774 T -72.2 -30.5 NA NA NA
1guh 1 P08263 95.02 2e-153 X-RAY
 1993-10-31 GLU A:114 A:115 140.0 0.737 T -59.9 -61.2 140.0 0.737 0.0
GLU B:114 B:115 139.0 0.732 T -59.9 -61.2 139.0 0.732 0.0
GLU C:114 C:115 139.0 0.732 T -59.9 -61.2 NA NA NA
GLU D:114 D:115 139.0 0.732 T -59.8 -61.2 NA NA NA
1k3l 1 P08263 95.02 2e-153 X-RAY
 2002-10-23 GLU A:114 A:115 174.0 0.916 H -76.7 -15.1 174.0 0.916 0.0 HOH
 2.296
 O
 O
GLU B:114 B:115 150.0 0.789 H -73.5 -14.0 150.0 0.789 0.0 HOH
 2.483
 OE1
 O
1k3o 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 GLU A:114 NA:NA DO NA DO DO DO NA NA NA
GLU B:114 B:115 150.0 0.789 G -70.5 -13.5 150.0 0.789 0.0 HOH
 2.523
 O
 O
1k3y 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 GLU A:114 A:115 171.0 0.9 H -62.7 -19.7 171.0 0.9 0.0 HOH
 2.712
 O
 O
GLU B:114 B:115 154.0 0.811 H -73.9 -12.1 154.0 0.811 0.0 HOH
 2.570
 OE2
 O
6ato 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 GLU A:114 A:115 158.0 0.832 H -70.8 -16.0 158.0 0.832 0.0 HOH
 2.989
 O
 O
GLU B:114 B:115 154.0 0.811 G -71.0 -15.0 NA NA NA
6atp 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 GLU A:114 A:115 191.0 1.0 T -81.8 -21.0 191.0 1.0 0.0 HOH
 2.749
 O
 O
GLU B:114 B:115 151.0 0.795 H -73.0 -10.5 NA NA NA
6atq 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 GLU A:114 A:115 154.0 0.811 G -71.0 -20.4 154.0 0.811 0.0 HOH
 2.986
 O
 O
GLU B:114 B:115 157.0 0.826 H -67.4 -15.3 NA NA NA
6atr 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 GLU A:114 A:115 197.0 1.0 H -65.1 -19.9 197.0 1.0 0.0 HOH
 2.500
 OE1
 O
GLU B:114 B:115 149.0 0.784 H -73.8 -11.2 NA NA NA
1pl2 1 P08263 94.59 4e-153 X-RAY
 2004-06-22 GLU A:115 A:115 148.0 0.779 H -84.8 -7.9 148.0 0.779 0.0 HOH
 2.816
 O
 O
GLU B:115 B:115 154.0 0.811 G -68.0 -17.9 154.0 0.811 0.0 HOH
 2.643
 O
 O
1usb 1 P08263 95.02 5e-153 X-RAY
 2004-09-01 GLU A:118 A:115 152.0 0.8 T -88.7 -31.4 152.0 0.8 0.0
GLU B:118 B:115 150.0 0.789 G -66.6 -19.9 150.0 0.789 0.0 HOH
 2.419
 OE1
 O
2r3x 1 P08263 94.59 6e-153 X-RAY
 2007-12-18 GLU A:115 A:115 170.0 0.895 T -81.9 -17.6 170.0 0.895 0.0 HOH
 2.668
 O
 O
GLU B:115 B:115 152.0 0.8 T -75.1 -13.2 152.0 0.8 0.0 HOH
 2.911
 O
 O
5jcu 1 P08263 95.02 8e-153 X-RAY
 2016-10-12 GLU A:114 A:115 145.0 0.763 T -88.3 5.6 145.0 0.763 0.0 HOH
 3.009
 O
 O
GLU B:114 B:115 151.0 0.795 H -76.2 -10.0 151.0 0.795 0.0 HOH
 2.680
 OE1
 O
GLU C:114 C:115 156.0 0.821 T -123.5 -35.7 NA NA NA
GLU D:114 D:115 148.0 0.779 T -100.9 5.1 NA NA NA
1gse 1 P08263 94.57 9e-153 X-RAY
 1995-09-15 GLU A:114 A:115 183.0 0.963 H -62.0 -37.3 183.0 0.963 0.0 HOH
 2.907
 O
 O
GLU B:114 B:115 154.0 0.811 H -66.0 -12.4 154.0 0.811 0.0 HOH
 2.741
 OE2
 O
3ktl 1 P08263 94.57 1e-152 X-RAY
 2009-12-22 GLU A:114 A:115 200.0 1.0 T -77.8 -7.5 200.0 1.0 0.0 HOH
 2.439
 O
 O
GLU B:114 B:115 150.0 0.789 G -73.3 -7.8 150.0 0.789 0.0 HOH
 2.640
 OE2
 O
3q74 1 P08263 94.57 1e-152 X-RAY
 2011-01-12 GLU A:114 A:115 154.0 0.811 T -78.0 -12.8 154.0 0.811 0.0 HOH
 3.297
 O
 O
GLU B:114 B:115 160.0 0.842 T -94.4 -25.9 160.0 0.842 0.0 HOH
 2.463
 O
 O
3l0h 1 P08263 94.59 2e-152 X-RAY
 2010-01-12 GLU A:115 A:115 173.0 0.911 T -73.1 -28.1 173.0 0.911 0.0 HOH
 2.909
 N
 O
GLU B:115 B:115 154.0 0.811 G -69.6 -13.4 154.0 0.811 0.0 HOH
 2.729
 O
 O
1xwg 1 P08263 94.57 5e-152 X-RAY
 2005-11-01 GLU A:114 A:115 178.0 0.937 T -89.1 -15.7 178.0 0.937 0.0 HOH
 2.798
 O
 O
GLU B:114 B:115 156.0 0.821 G -70.3 -18.5 156.0 0.821 0.0 HOH
 2.409
 OE2
 O
4hj2 1 P08263 94.93 4e-150 X-RAY
 2013-03-27 GLU A:112 A:115 158.0 0.832 G -54.2 -13.0 158.0 0.832 0.0 HOH
 2.910
 O
 O
GLU B:112 NA:NA DO NA DO DO DO NA NA NA
3i69 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 GLU A:115 A:115 154.0 0.811 G -66.2 -27.6 154.0 0.811 0.0
GLU B:115 B:115 195.0 1.0 H -56.2 -33.3 195.0 1.0 0.0
GLU C:115 C:115 155.0 0.816 T -74.3 22.1 NA NA NA
GLU D:115 D:115 167.0 0.879 G -54.3 -39.9 NA NA NA
GLU E:115 E:115 153.0 0.805 H -65.8 -29.0 NA NA NA
GLU F:115 F:115 186.0 0.979 H -66.2 -25.5 NA NA NA
GLU G:115 G:115 156.0 0.821 T -60.8 -44.2 NA NA NA
GLU H:115 H:115 158.0 0.832 T -57.8 -55.1 NA NA NA
3i6a 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 GLU A:115 A:115 150.0 0.789 H -66.1 -13.1 150.0 0.789 0.0
GLU B:115 B:115 169.0 0.889 H -80.4 -32.4 169.0 0.889 0.0
GLU C:115 C:115 155.0 0.816 T -80.8 -5.7 NA NA NA
GLU D:115 D:115 172.0 0.905 H -61.9 -28.6 NA NA NA
GLU E:115 E:115 161.0 0.847 G -65.0 -37.7 NA NA NA
GLU F:115 F:115 169.0 0.889 H -58.7 -42.9 NA NA NA
GLU G:115 G:115 156.0 0.821 G -68.0 -24.4 NA NA NA
GLU H:115 H:115 167.0 0.879 H -55.3 -46.1 NA NA NA
3ik9 1 P08263 90.95 3e-145 X-RAY
 2010-06-23 GLU A:115 A:115 146.0 0.768 G -61.7 -19.1 146.0 0.768 0.0
GLU B:115 B:115 150.0 0.789 H -45.2 -35.2 150.0 0.789 0.0
GLU C:115 C:115 150.0 0.789 T -89.6 9.6 NA NA NA
GLU D:115 D:115 171.0 0.9 H -30.9 -54.4 NA NA NA
GLU E:115 E:115 170.0 0.895 H -70.4 -20.3 NA NA NA
GLU F:115 F:115 149.0 0.784 T -75.1 -29.0 NA NA NA
GLU G:115 G:115 161.0 0.847 H -55.5 -29.0 NA NA NA
GLU H:115 H:115 127.0 0.668 T -73.3 -40.0 NA NA NA
1tdi 1 Q16772 88.74 4e-143 X-RAY
 2005-01-18 GLU A:115 A:115 124.0 0.653 H -74.3 -15.0 124.0 0.653 0.0 HOH
 2.773
 O
 O
GLU B:115 B:115 129.0 0.679 H -85.2 -22.3 129.0 0.679 0.0
2vcv 1 Q16772 88.74 4e-143 X-RAY
 2008-10-28 GLU A:115 A:115 127.0 0.668 H -75.9 -25.9 127.0 0.668 0.0 HOH
 2.414
 O
 O
GLU B:115 B:115 155.0 0.816 T -77.0 -19.1 155.0 0.816 0.0 HOH
 2.665
 O
 O
GLU C:115 C:115 155.0 0.816 H -74.8 -39.2 NA NA NA
GLU D:115 D:115 138.0 0.726 H -63.0 -26.2 NA NA NA
GLU E:115 E:115 143.0 0.753 H -72.4 -31.5 NA NA NA
GLU F:115 F:115 139.0 0.732 H -90.1 4.0 NA NA NA
GLU G:115 G:115 145.0 0.763 H -67.7 -21.1 NA NA NA
GLU H:115 H:115 138.0 0.726 H -75.4 -9.1 NA NA NA
GLU I:115 I:115 155.0 0.816 H -64.0 -25.9 NA NA NA
GLU J:115 J:115 149.0 0.784 T -74.2 -39.4 NA NA NA
GLU K:115 K:115 131.0 0.689 H -71.2 -23.6 NA NA NA
GLU L:115 L:115 144.0 0.758 T -91.5 -5.4 NA NA NA
GLU M:115 M:115 129.0 0.679 T -89.7 -5.9 NA NA NA
GLU N:115 N:115 146.0 0.768 T -81.6 -28.0 NA NA NA
GLU O:115 O:115 136.0 0.716 H -76.3 -19.0 NA NA NA
GLU P:115 P:115 132.0 0.695 H -74.7 -26.2 NA NA NA
5lcz 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 ASP A:115 NA:NA DO NA DO DO DO NA NA NA
ASP B:115 B:115 141.0 0.94 H -31.8 -51.4 141.0 0.94 0.0
5ld0 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 ASP A:115 A:115 126.0 0.84 H -80.6 -7.9 126.0 0.84 0.0 HOH
 2.693
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09210-f1 1 P09210 100.0 3e-163 GLU A:115 A:115 160.0 0.842 H -72.1 -16.1
af-p08263-f1 1 P08263 95.05 1e-154 GLU A:115 A:115 152.0 0.8 H -67.5 -20.9
af-q7rtv2-f1 1 Q7RTV2 88.74 1e-143 GLU A:115 A:115 158.0 0.832 G -70.2 -21.8
af-q16772-f1 1 Q16772 88.74 2e-143 GLU A:115 A:115 130.0 0.684 H -68.5 -18.6