Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52617731 . C A CCDS4944.1:NM_000846.4:c.335aGt>aTt_NP_000837.3:p.112S>I Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2vct 1 P09210 99.55 1e-162 X-RAY
 2008-10-28 THR A:112 A:112 20.0 0.143 S -89.0 155.5 20.0 0.143 0.0 ASD
HOH
 4.756
2.783
 CA
O
 O1
O
THR B:112 B:112 17.0 0.121 S -79.7 154.8 17.0 0.121 0.0 ASD
HOH
 5.360
2.974
 CA
O
 O1
O
THR C:112 C:112 28.0 0.2 S -74.5 157.3 NA NA NA
THR D:112 D:112 20.0 0.143 S -87.5 157.5 NA NA NA
THR E:112 E:112 23.0 0.164 S -80.9 148.0 NA NA NA
THR F:112 F:112 21.0 0.15 S -99.0 154.3 NA NA NA
THR G:112 G:112 29.0 0.207 S -72.2 152.4 NA NA NA
THR H:112 H:112 26.0 0.186 S -74.1 165.2 NA NA NA
2wju 1 P09210 99.55 1e-162 X-RAY
 2009-06-09 THR A:112 A:112 27.0 0.193 S -73.8 128.8 27.0 0.193 0.0
THR B:112 B:112 21.0 0.15 S -67.7 155.0 21.0 0.15 0.0
THR C:112 C:112 18.0 0.129 S -83.4 145.7 NA NA NA
THR D:112 D:112 16.0 0.114 S -69.4 144.6 NA NA NA
THR E:112 E:112 18.0 0.129 S -62.5 157.0 NA NA NA
THR F:112 F:112 48.0 0.343 S -140.0 156.5 NA NA NA
THR G:112 G:112 16.0 0.114 S -77.4 149.6 NA NA NA
THR H:112 H:112 18.0 0.129 S -62.6 133.0 NA NA NA
4acs 1 P09210 98.64 2e-158 X-RAY
 2011-12-28 SER A:112 A:112 13.0 0.113 S -73.0 158.6 13.0 0.113 0.0 HOH
 3.863
 OG
 O
SER B:112 B:112 11.0 0.096 S -69.7 151.8 11.0 0.096 0.0 HOH
 5.611
 OG
 O
SER C:112 C:112 14.0 0.122 S -94.7 159.9 NA NA NA
SER D:112 D:112 9.0 0.078 S -94.6 134.5 NA NA NA
1pkw 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 CSO A:112 A:112 NA NA NA NA NA NA NA NA HOH
 5.328
 SG
 O
CSO B:112 B:112 NA NA NA NA NA NA NA NA HOH
 7.066
 O
 O
1pkz 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 CSO A:112 A:112 NA NA NA NA NA NA NA NA HOH
 8.694
 N
 O
CSO B:112 B:112 NA NA NA NA NA NA NA NA HOH
 3.912
 OD
 O
1pl1 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 CSO A:112 A:112 NA NA NA NA NA NA NA NA ABY
HOH
 7.837
3.965
 N
SG
 C7'
O
CSO B:112 B:112 NA NA NA NA NA NA NA NA ABY
HOH
 7.852
2.878
 N
O
 C7'
O
6yaw 1 P08263 95.05 4e-154 X-RAY
 2020-08-26 CYS A:112 A:112 32.0 0.237 S -88.3 152.4 32.0 0.237 0.0 P9H
HOH
 8.332
7.444
 N
N
 C5
O
CYS B:112 B:112 19.0 0.141 S -65.4 150.9 19.0 0.141 0.0 P9H
HOH
 7.994
7.227
 N
O
 C5
O
2r6k 1 P08263 94.59 5e-154 X-RAY
 2008-08-19 CYS A:112 A:112 25.0 0.185 S -52.5 145.0 25.0 0.185 0.0 GTX
HOH
 7.311
4.526
 N
SG
 C6S
O
CYS B:112 B:112 14.0 0.104 S -21.5 135.4 14.0 0.104 0.0 GTX
HOH
 7.956
4.666
 N
O
 C6S
O
3zfl 1 P08263 94.59 1e-153 X-RAY
 2012-12-19 CYS A:112 A:112 15.0 0.111 S -74.8 159.5 15.0 0.111 0.0 HOH
 3.678
 O
 O
CYS B:112 B:112 16.0 0.119 S -65.7 132.1 16.0 0.119 0.0 HOH
 2.887
 O
 O
3zfb 1 P08263 94.59 2e-153 X-RAY
 2012-12-19 CYS A:112 A:112 12.0 0.089 S -64.9 137.3 12.0 0.089 0.0 HOH
 5.722
 CB
 O
CYS B:112 B:112 11.0 0.081 S -59.8 133.8 11.0 0.081 0.0 HOH
 2.982
 CB
 O
1ydk 1 P08263 94.59 2e-153 X-RAY
 2005-06-07 CYS A:112 A:112 22.0 0.163 S -59.3 134.1 22.0 0.163 0.0 GTX
HOH
 8.199
8.803
 N
N
 C6S
O
CYS B:112 B:112 17.0 0.126 S -61.8 140.2 17.0 0.126 0.0 GTX
HOH
 7.545
5.109
 N
SG
 C6S
O
3u6v 1 P08263 94.59 2e-153 X-RAY
 2011-10-26 CYS A:112 A:112 27.0 0.2 S -109.8 166.6 27.0 0.2 0.0 HOH
 2.595
 SG
 O
CYS B:112 B:112 19.0 0.141 S -74.2 140.4 19.0 0.141 0.0 HOH
 3.271
 CA
 O
1gsd 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 CYS A:111 A:112 17.0 0.126 S -76.0 134.7 17.0 0.126 0.0 HOH
 9.368
 N
 O
CYS B:111 B:112 17.0 0.126 S -76.0 134.7 17.0 0.126 0.0 HOH
 9.369
 N
 O
CYS C:111 C:112 17.0 0.126 S -75.9 134.7 NA NA NA
CYS D:111 D:112 16.0 0.119 S -76.1 134.7 NA NA NA
1gsf 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 CYS A:111 A:112 17.0 0.126 S -81.0 140.1 17.0 0.126 0.0 EAA
 7.015
 N
 C10
CYS B:111 B:112 16.0 0.119 S -80.9 140.1 16.0 0.119 0.0 EAA
 7.015
 N
 C10
CYS C:111 C:112 16.0 0.119 S -81.0 140.0 NA NA NA
CYS D:111 D:112 18.0 0.133 S -80.9 140.0 NA NA NA
1guh 1 P08263 95.02 2e-153 X-RAY
 1993-10-31 CYS A:111 A:112 22.0 0.163 S -65.9 138.0 22.0 0.163 0.0 GSB
 9.269
 N
 C4'
CYS B:111 B:112 23.0 0.17 S -66.0 138.0 23.0 0.17 0.0 GSB
 9.270
 N
 C4'
CYS C:111 C:112 22.0 0.163 S -65.9 138.0 NA NA NA
CYS D:111 D:112 21.0 0.156 S -65.9 137.9 NA NA NA
1k3l 1 P08263 95.02 2e-153 X-RAY
 2002-10-23 CYS A:111 A:112 36.0 0.267 S -82.5 148.4 36.0 0.267 0.0 GTX
HOH
 7.281
4.606
 N
SG
 C6S
O
CYS B:111 B:112 26.0 0.193 S -69.3 152.4 26.0 0.193 0.0 GTX
HOH
 7.476
2.646
 N
O
 C6S
O
1k3o 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 CYS A:111 NA:NA DO NA DO DO DO NA NA NA
CYS B:111 B:112 29.0 0.215 S -68.5 158.7 29.0 0.215 0.0 HOH
 7.114
 SG
 O
1k3y 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 CYS A:111 A:112 43.0 0.319 S -77.6 142.6 43.0 0.319 0.0 GTX
HOH
 7.342
4.673
 N
SG
 C6S
O
CYS B:111 B:112 19.0 0.141 S -66.2 145.9 19.0 0.141 0.0 GTX
HOH
 7.352
2.670
 N
O
 C6S
O
6ato 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 CYS A:111 A:112 14.0 0.104 S -75.2 137.0 14.0 0.104 0.0 MPD
HOH
 7.010
3.509
 N
CB
 H12
O
CYS B:111 B:112 12.0 0.089 S -65.7 137.6 NA NA NA
6atp 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 CYS A:111 A:112 20.0 0.148 S -76.1 139.6 20.0 0.148 0.0 HOH
 3.127
 CB
 O
CYS B:111 B:112 16.0 0.119 S -60.3 134.6 NA NA NA
6atq 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 CYS A:111 A:112 9.0 0.067 S -63.0 131.2 9.0 0.067 0.0 MPD
MES
HOH
 8.844
8.844
6.878
 N
N
SG
 HM3
O3S
O
CYS B:111 B:112 17.0 0.126 S -62.1 133.4 NA NA NA
6atr 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 CYS A:111 A:112 16.0 0.119 S -72.4 134.6 16.0 0.119 0.0 EDO
HOH
 7.818
3.185
 N
CB
 O2
O
CYS B:111 B:112 16.0 0.119 S -60.7 135.0 NA NA NA
1pl2 1 P08263 94.59 4e-153 X-RAY
 2004-06-22 CSO A:112 A:112 NA NA NA NA NA NA NA NA ABY
HOH
 7.902
3.992
 N
SG
 C7'
O
CSO B:112 B:112 NA NA NA NA NA NA NA NA ABY
HOH
 7.673
3.660
 N
SG
 C7'
O
1usb 1 P08263 95.02 5e-153 X-RAY
 2004-09-01 CYS A:115 A:112 19.0 0.141 S -105.7 168.1 19.0 0.141 0.0
CYS B:115 B:112 16.0 0.119 S -73.2 155.3 16.0 0.119 0.0 HOH
 5.493
 CB
 O
2r3x 1 P08263 94.59 6e-153 X-RAY
 2007-12-18 CYS A:112 A:112 27.0 0.2 S -71.1 139.8 27.0 0.2 0.0 GTX
HOH
 7.552
4.509
 N
N
 C6S
O
CYS B:112 B:112 25.0 0.185 S -65.8 150.1 25.0 0.185 0.0 GTX
HOH
 7.620
2.436
 N
O
 C6S
O
5jcu 1 P08263 95.02 8e-153 X-RAY
 2016-10-12 6M6 A:111 A:112 26.0 NA S -71.0 139.9 26.0 NA NA GVX
HOH
 6.885
7.555
 N
CB
 C29
O
6M6 B:111 B:112 15.0 NA S -62.7 139.3 15.0 NA NA GVX
HOH
 7.485
2.845
 N
O
 C29
O
6M6 C:111 C:112 27.0 NA S -73.9 143.8 NA NA NA
6M6 D:111 D:112 19.0 NA S -77.1 146.9 NA NA NA
1gse 1 P08263 94.57 9e-153 X-RAY
 1995-09-15 CYS A:111 A:112 21.0 0.156 S -91.0 146.5 21.0 0.156 0.0 EAA
HOH
 7.333
4.565
 N
SG
 CL1
O
CYS B:111 B:112 16.0 0.119 S -72.0 140.4 16.0 0.119 0.0 EAA
HOH
 7.026
5.101
 N
CB
 CL1
O
3ktl 1 P08263 94.57 1e-152 X-RAY
 2009-12-22 CYS A:111 A:112 12.0 0.089 S -77.4 143.4 12.0 0.089 0.0 GTX
HOH
 7.061
2.419
 N
O
 C6S
O
CYS B:111 B:112 17.0 0.126 S -69.7 139.3 17.0 0.126 0.0 GTX
HOH
 8.167
2.329
 N
O
 C6S
O
3q74 1 P08263 94.57 1e-152 X-RAY
 2011-01-12 CYS A:111 A:112 15.0 0.111 S -64.6 136.2 15.0 0.111 0.0 HOH
 2.971
 CB
 O
CYS B:111 B:112 41.0 0.304 S -106.1 171.9 41.0 0.304 0.0 HOH
 3.335
 CB
 O
3l0h 1 P08263 94.59 2e-152 X-RAY
 2010-01-12 CYS A:112 A:112 20.0 0.148 S -71.6 149.1 20.0 0.148 0.0 GTX
HOH
 8.008
4.602
 N
O
 C6S
O
CYS B:112 B:112 19.0 0.141 S -83.9 137.0 19.0 0.141 0.0 GTX
HOH
 7.228
2.637
 N
O
 C6S
O
1xwg 1 P08263 94.57 5e-152 X-RAY
 2005-11-01 CYS A:111 A:112 23.0 0.17 S -68.5 151.5 23.0 0.17 0.0 HOH
 7.298
 SG
 O
CYS B:111 B:112 22.0 0.163 S -61.6 136.8 22.0 0.163 0.0 HOH
 4.505
 SG
 O
4hj2 1 P08263 94.93 4e-150 X-RAY
 2013-03-27 CYS A:109 A:112 17.0 0.126 S -57.0 143.2 17.0 0.126 0.0 LZ6
HOH
 7.026
2.492
 N
O
 C15
O
CYS B:109 NA:NA DO NA DO DO DO NA NA NA
3i69 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 CYS A:112 A:112 22.0 0.163 S -71.2 152.8 22.0 0.163 0.0
CYS B:112 B:112 19.0 0.141 S -72.2 146.9 19.0 0.141 0.0
CYS C:112 C:112 19.0 0.141 S -64.7 147.6 NA NA NA
CYS D:112 D:112 22.0 0.163 S -73.3 152.7 NA NA NA
CYS E:112 E:112 29.0 0.215 S -61.6 152.1 NA NA NA
CYS F:112 F:112 25.0 0.185 S -95.5 157.7 NA NA NA
CYS G:112 G:112 30.0 0.222 S -66.7 147.6 NA NA NA
CYS H:112 H:112 31.0 0.23 S -71.6 159.9 NA NA NA
3i6a 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 CYS A:112 A:112 14.0 0.104 S -77.2 150.8 14.0 0.104 0.0
CYS B:112 B:112 17.0 0.126 S -97.9 151.2 17.0 0.126 0.0 HOH
 8.915
 N
 O
CYS C:112 C:112 20.0 0.148 S -64.4 151.6 NA NA NA
CYS D:112 D:112 21.0 0.156 S -69.5 152.8 NA NA NA
CYS E:112 E:112 32.0 0.237 S -85.5 158.8 NA NA NA
CYS F:112 F:112 21.0 0.156 S -66.7 150.1 NA NA NA
CYS G:112 G:112 17.0 0.126 S -66.7 144.8 NA NA NA
CYS H:112 H:112 25.0 0.185 S -77.2 154.4 NA NA NA
3ik9 1 P08263 90.95 3e-145 X-RAY
 2010-06-23 CYS A:112 A:112 22.0 0.163 S -71.9 160.2 22.0 0.163 0.0 BOB
 7.088
 N
 C47
CYS B:112 B:112 14.0 0.104 S -95.1 154.4 14.0 0.104 0.0 BOB
 8.220
 N
 C46
CYS C:112 C:112 17.0 0.126 S -45.3 148.4 NA NA NA
CYS D:112 D:112 14.0 0.104 S -68.4 138.1 NA NA NA
CYS E:112 E:112 23.0 0.17 S -79.2 158.5 NA NA NA
CYS F:112 F:112 14.0 0.104 S -84.6 152.0 NA NA NA
CYS G:112 G:112 22.0 0.163 S -76.4 151.6 NA NA NA
CYS H:112 H:112 24.0 0.178 S -68.9 140.9 NA NA NA
1tdi 1 Q16772 88.74 4e-143 X-RAY
 2005-01-18 CYS A:112 A:112 25.0 0.185 S -67.2 138.1 25.0 0.185 0.0 HOH
 2.913
 SG
 O
CYS B:112 B:112 26.0 0.193 S -67.9 139.2 26.0 0.193 0.0
2vcv 1 Q16772 88.74 4e-143 X-RAY
 2008-10-28 CYS A:112 A:112 30.0 0.222 S -77.4 134.2 30.0 0.222 0.0 ASD
HOH
 7.883
3.127
 N
SG
 C12
O
CYS B:112 B:112 23.0 0.17 S -63.8 133.3 23.0 0.17 0.0 ASD
HOH
 8.114
3.902
 N
SG
 C12
O
CYS C:112 C:112 21.0 0.156 S -65.6 134.7 NA NA NA
CYS D:112 D:112 30.0 0.222 S -69.3 132.6 NA NA NA
CYS E:112 E:112 21.0 0.156 S -77.3 137.9 NA NA NA
CYS F:112 F:112 27.0 0.2 S -62.6 132.7 NA NA NA
CYS G:112 G:112 28.0 0.207 S -70.3 135.4 NA NA NA
CYS H:112 H:112 21.0 0.156 S -66.6 139.8 NA NA NA
CYS I:112 I:112 24.0 0.178 S -59.5 133.8 NA NA NA
CYS J:112 J:112 25.0 0.185 S -80.7 135.3 NA NA NA
CYS K:112 K:112 23.0 0.17 S -66.1 130.6 NA NA NA
CYS L:112 L:112 24.0 0.178 S -67.4 128.0 NA NA NA
CYS M:112 M:112 26.0 0.193 S -71.5 136.1 NA NA NA
CYS N:112 N:112 29.0 0.215 S -63.8 147.4 NA NA NA
CYS O:112 O:112 28.0 0.207 S -70.1 133.9 NA NA NA
CYS P:112 P:112 24.0 0.178 S -64.4 131.3 NA NA NA
5lcz 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 CYS A:112 NA:NA DO NA DO DO DO NA NA NA
CYS B:112 B:112 11.0 0.081 S -65.4 165.4 11.0 0.081 0.0 HOH
 7.891
 CB
 O
5ld0 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 CYS A:112 A:112 16.0 0.119 S -71.0 150.2 16.0 0.119 0.0 HOH
 2.972
 SG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09210-f1 1 P09210 100.0 3e-163 SER A:112 A:112 13.0 0.113 S -75.0 151.9
af-p08263-f1 1 P08263 95.05 1e-154 CYS A:112 A:112 16.0 0.119 S -65.1 143.0
af-q7rtv2-f1 1 Q7RTV2 88.74 1e-143 CYS A:112 A:112 23.0 0.17 S -68.9 158.2
af-q16772-f1 1 Q16772 88.74 2e-143 CYS A:112 A:112 19.0 0.141 S -70.8 150.3