Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52617783 . A C CCDS4944.1:NM_000846.4:c.283Tat>Gat_NP_000837.3:p.95Y>D Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2vct 1 P09210 99.55 1e-162 X-RAY
 2008-10-28 TYR A:95 A:95 31.0 0.135 H -65.9 -50.8 19.0 0.083 0.052 B:P09210:0.052
 HOH
 2.478
 OH
 O
TYR B:95 B:95 35.0 0.152 H -66.7 -48.4 23.0 0.1 0.052 A:P09210:0.052
 HOH
 2.459
 OH
 O
TYR C:95 C:95 33.0 0.143 H -66.0 -49.1 NA NA NA
TYR D:95 D:95 35.0 0.152 H -71.0 -46.7 NA NA NA
TYR E:95 E:95 33.0 0.143 H -58.1 -50.9 NA NA NA
TYR F:95 F:95 30.0 0.13 H -68.9 -51.0 NA NA NA
TYR G:95 G:95 29.0 0.126 H -70.5 -51.2 NA NA NA
TYR H:95 H:95 34.0 0.148 H -65.7 -50.9 NA NA NA
2wju 1 P09210 99.55 1e-162 X-RAY
 2009-06-09 TYR A:95 A:95 32.0 0.139 H -63.5 -50.0 18.0 0.078 0.061 B:P09210:0.061
 GSH
HOH
 9.238
6.411
 O
OH
 N1
O
TYR B:95 B:95 29.0 0.126 H -70.8 -48.2 17.0 0.074 0.052 A:P09210:0.052
 GSH
HOH
 9.547
2.856
 O
OH
 N1
O
TYR C:95 C:95 34.0 0.148 H -63.7 -49.8 NA NA NA
TYR D:95 D:95 35.0 0.152 H -71.0 -47.1 NA NA NA
TYR E:95 E:95 34.0 0.148 H -66.3 -51.6 NA NA NA
TYR F:95 F:95 37.0 0.161 H -61.4 -51.3 NA NA NA
TYR G:95 G:95 35.0 0.152 H -77.6 -47.5 NA NA NA
TYR H:95 H:95 31.0 0.135 H -67.6 -56.4 NA NA NA
4acs 1 P09210 98.64 2e-158 X-RAY
 2011-12-28 TYR A:95 A:95 30.0 0.13 H -63.2 -42.1 20.0 0.087 0.043 B:P09210:0.043
 GSH
HOH
 9.398
2.553
 O
OH
 N1
O
TYR B:95 B:95 30.0 0.13 H -59.2 -59.3 20.0 0.087 0.043 A:P09210:0.043
 GSH
HOH
 9.285
6.164
 O
CE1
 N1
O
TYR C:95 C:95 32.0 0.139 H -71.3 -45.2 NA NA NA
TYR D:95 D:95 25.0 0.109 H -71.1 -46.3 NA NA NA
1pkw 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 TYR A:95 A:95 34.0 0.148 H -63.7 -47.0 21.0 0.091 0.057 B:P08263:0.057
 HED
GSH
HOH
 6.535
9.735
2.839
 O
O
OH
 S4
N1
O
TYR B:95 B:95 32.0 0.139 H -66.6 -45.4 20.0 0.087 0.052 A:P08263:0.052
 GSH
HED
HOH
 9.586
6.574
2.647
 O
O
OH
 N1
S3
O
1pkz 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 TYR A:95 A:95 32.0 0.139 H -64.9 -49.3 19.0 0.083 0.056 B:P08263:0.057
 HED
HOH
 6.361
2.723
 O
OH
 S4
O
TYR B:95 B:95 33.0 0.143 H -61.0 -52.6 20.0 0.087 0.056 A:P08263:0.057
 HED
HOH
 6.320
2.580
 O
OH
 S4
O
1pl1 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 TYR A:95 A:95 34.0 0.148 H -61.4 -49.4 20.0 0.087 0.061 B:P08263:0.061
 ABY
HOH
 9.756
2.721
 O
OH
 N1
O
TYR B:95 B:95 33.0 0.143 H -64.7 -47.0 20.0 0.087 0.056 A:P08263:0.057
 ABY
HOH
 9.728
2.651
 O
OH
 N1
O
6yaw 1 P08263 95.05 4e-154 X-RAY
 2020-08-26 TYR A:95 A:95 33.0 0.143 H -60.0 -50.8 18.0 0.078 0.065 B:P08263:0.065
 P9H
HOH
 9.572
3.152
 O
OH
 N1
O
TYR B:95 B:95 32.0 0.139 H -66.9 -53.9 21.0 0.091 0.048 A:P08263:0.048
 P9H
HOH
 9.561
2.258
 O
OH
 N1
O
2r6k 1 P08263 94.59 5e-154 X-RAY
 2008-08-19 TYR A:95 A:95 33.0 0.143 H -54.0 -56.5 22.0 0.096 0.047 B:P08263:0.048
 GTX
HOH
 9.460
2.758
 O
OH
 N1
O
TYR B:95 B:95 31.0 0.135 H -55.6 -54.4 19.0 0.083 0.052 A:P08263:0.052
 GTX
HOH
 9.332
5.928
 O
O
 N1
O
3zfl 1 P08263 94.59 1e-153 X-RAY
 2012-12-19 TYR A:95 A:95 33.0 0.143 H -68.7 -49.7 22.0 0.096 0.047 B:P08263:0.048
 HOH
 2.652
 OH
 O
TYR B:95 B:95 34.0 0.148 H -62.2 -45.4 21.0 0.091 0.057 A:P08263:0.057
 HOH
 2.435
 OH
 O
3zfb 1 P08263 94.59 2e-153 X-RAY
 2012-12-19 TYR A:95 A:95 31.0 0.135 H -63.8 -47.4 19.0 0.083 0.052 B:P08263:0.052
 HOH
 2.585
 OH
 O
TYR B:95 B:95 34.0 0.148 H -62.2 -45.8 20.0 0.087 0.061 A:P08263:0.061
 HOH
 2.629
 OH
 O
1ydk 1 P08263 94.59 2e-153 X-RAY
 2005-06-07 TYR A:95 A:95 29.0 0.126 H -62.8 -51.1 18.0 0.078 0.048 B:P08263:0.048
 GTX
HOH
 9.624
2.478
 O
OH
 N1
O
TYR B:95 B:95 33.0 0.143 H -61.0 -50.6 22.0 0.096 0.047 A:P08263:0.048
 GTX
HOH
 9.682
2.815
 O
OH
 N1
O
3u6v 1 P08263 94.59 2e-153 X-RAY
 2011-10-26 TYR A:95 A:95 29.0 0.126 H -68.6 -50.2 18.0 0.078 0.048 B:P08263:0.048
 HOH
 3.142
 OH
 O
TYR B:95 B:95 33.0 0.143 H -52.6 -46.2 22.0 0.096 0.047 A:P08263:0.048
 HOH
 2.662
 OH
 O
1gsd 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 TYR A:94 A:95 37.0 0.161 H -65.2 -50.4 20.0 0.087 0.074 B:P08263:0.074
 HOH
 2.646
 OH
 O
TYR B:94 B:95 35.0 0.152 H -65.2 -50.5 20.0 0.087 0.065 A:P08263:0.065
 HOH
 2.647
 OH
 O
TYR C:94 C:95 37.0 0.161 H -65.2 -50.4 NA NA NA
TYR D:94 D:95 36.0 0.157 H -65.2 -50.4 NA NA NA
1gsf 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 TYR A:94 A:95 37.0 0.161 H -74.7 -48.3 15.0 0.065 0.096 B:P08263:0.096
 HOH
 2.682
 OH
 O
TYR B:94 B:95 35.0 0.152 H -74.6 -48.3 15.0 0.065 0.087 A:P08263:0.087
 HOH
 2.682
 OH
 O
TYR C:94 C:95 37.0 0.161 H -74.7 -48.3 NA NA NA
TYR D:94 D:95 35.0 0.152 H -74.7 -48.2 NA NA NA
1guh 1 P08263 95.02 2e-153 X-RAY
 1993-10-31 TYR A:94 A:95 36.0 0.157 H -67.4 -51.5 23.0 0.1 0.057 B:P08263:0.057
 GSB
 9.742
 O
 N1
TYR B:94 B:95 36.0 0.157 H -67.4 -51.5 22.0 0.096 0.061 A:P08263:0.061
 GSB
 9.625
 O
 N1
TYR C:94 C:95 38.0 0.165 H -67.4 -51.6 NA NA NA
TYR D:94 D:95 35.0 0.152 H -67.4 -51.5 NA NA NA
1k3l 1 P08263 95.02 2e-153 X-RAY
 2002-10-23 TYR A:94 A:95 33.0 0.143 H -63.7 -47.2 20.0 0.087 0.056 B:P08263:0.057
 GTX
HOH
 9.569
2.698
 O
OH
 N1
O
TYR B:94 B:95 33.0 0.143 H -63.4 -47.6 21.0 0.091 0.052 A:P08263:0.052
 GTX
HOH
 9.656
2.570
 O
OH
 N1
O
1k3o 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 TYR A:94 A:95 39.0 0.17 H -70.2 -48.9 18.0 0.078 0.092 B:P08263:0.091
 HOH
 2.741
 OH
 O
TYR B:94 B:95 38.0 0.165 H -68.1 -50.3 18.0 0.078 0.087 A:P08263:0.087
 HOH
 3.297
 OH
 O
1k3y 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 TYR A:94 A:95 30.0 0.13 H -64.9 -45.9 17.0 0.074 0.056 B:P08263:0.057
 GOL
GTX
HOH
 6.212
9.602
2.687
 O
O
OH
 O1
N1
O
TYR B:94 B:95 32.0 0.139 H -61.6 -49.0 19.0 0.083 0.056 A:P08263:0.057
 GTX
HOH
 9.670
2.622
 O
OH
 N1
O
6ato 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 TYR A:94 A:95 37.0 0.161 H -62.0 -49.9 37.0 0.161 0.0 HOH
 2.783
 OH
 O
TYR B:94 B:95 33.0 0.143 H -62.4 -48.6 NA NA NA
6atp 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 TYR A:94 A:95 33.0 0.143 H -62.3 -51.5 33.0 0.143 0.0 HOH
 2.749
 OH
 O
TYR B:94 B:95 34.0 0.148 H -61.9 -50.7 NA NA NA
6atq 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 TYR A:94 A:95 32.0 0.139 H -61.5 -51.8 32.0 0.139 0.0 HOH
 2.791
 OH
 O
TYR B:94 B:95 34.0 0.148 H -60.9 -51.5 NA NA NA
6atr 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 TYR A:94 A:95 33.0 0.143 H -65.5 -46.3 33.0 0.143 0.0 EDO
HOH
 5.350
2.631
 O
OH
 HO1
O
TYR B:94 B:95 33.0 0.143 H -66.4 -46.0 NA NA NA
1pl2 1 P08263 94.59 4e-153 X-RAY
 2004-06-22 TYR A:95 A:95 33.0 0.143 H -63.0 -47.0 21.0 0.091 0.052 B:P08263:0.052
 ABY
HOH
 9.724
2.733
 O
OH
 N1
O
TYR B:95 B:95 32.0 0.139 H -63.5 -47.2 19.0 0.083 0.056 A:P08263:0.057
 ABY
HOH
 9.673
2.645
 O
OH
 N1
O
1usb 1 P08263 95.02 5e-153 X-RAY
 2004-09-01 TYR A:98 A:95 26.0 0.113 H -71.2 -51.7 13.0 0.057 0.056 B:P08263:0.057
 CL
K
GSH
HOH
 8.732
6.851
9.611
2.596
 C
CD1
O
OH
 CL
K
N1
O
TYR B:98 B:95 22.0 0.096 H -66.3 -46.1 9.0 0.039 0.057 A:P08263:0.057
 GSH
CL
K
HOH
 9.644
8.674
6.943
2.627
 O
C
CD2
OH
 N1
CL
K
O
2r3x 1 P08263 94.59 6e-153 X-RAY
 2007-12-18 TYR A:95 A:95 33.0 0.143 H -58.0 -48.2 22.0 0.096 0.047 B:P08263:0.048
 GTX
HOH
 9.563
2.749
 O
OH
 N1
O
TYR B:95 B:95 33.0 0.143 H -61.9 -48.6 21.0 0.091 0.052 A:P08263:0.052
 GTX
HOH
 9.473
2.661
 O
OH
 N1
O
5jcu 1 P08263 95.02 8e-153 X-RAY
 2016-10-12 TYR A:94 A:95 35.0 0.152 H -61.2 -46.3 22.0 0.096 0.056 B:P08263:0.057
 EDO
GVX
HOH
 6.064
9.690
2.512
 O
O
OH
 O2
N05
O
TYR B:94 B:95 32.0 0.139 H -69.3 -52.2 21.0 0.091 0.048 A:P08263:0.048
 GVX
HOH
 9.659
2.429
 O
OH
 N05
O
TYR C:94 C:95 30.0 0.13 H -63.4 -48.6 NA NA NA
TYR D:94 D:95 32.0 0.139 H -60.4 -45.1 NA NA NA
1gse 1 P08263 94.57 9e-153 X-RAY
 1995-09-15 TYR A:94 A:95 32.0 0.139 H -64.7 -51.8 19.0 0.083 0.056 B:P08263:0.057
 BME
BME
GSH
HOH
 6.347
7.270
9.592
2.602
 O
C
O
OH
 S2
C1
N1
O
TYR B:94 B:95 34.0 0.148 H -67.4 -51.3 21.0 0.091 0.057 A:P08263:0.057
 GSH
BME
BME
HOH
 9.743
6.299
7.207
2.633
 O
O
C
OH
 N1
S2
C1
O
3ktl 1 P08263 94.57 1e-152 X-RAY
 2009-12-22 TYR A:94 A:95 31.0 0.135 H -66.6 -46.7 19.0 0.083 0.052 B:P08263:0.052
 GTX
HOH
 9.713
2.744
 O
OH
 N1
O
TYR B:94 B:95 37.0 0.161 H -64.3 -44.9 24.0 0.104 0.057 A:P08263:0.057
 GTX
HOH
 9.861
2.511
 O
OH
 N1
O
3q74 1 P08263 94.57 1e-152 X-RAY
 2011-01-12 TYR A:94 A:95 35.0 0.152 H -57.6 -49.7 20.0 0.087 0.065 B:P08263:0.065
 HOH
 2.610
 OH
 O
TYR B:94 B:95 33.0 0.143 H -59.5 -45.7 17.0 0.074 0.069 A:P08263:0.07
 HOH
 2.486
 OH
 O
3l0h 1 P08263 94.59 2e-152 X-RAY
 2010-01-12 TYR A:95 A:95 35.0 0.152 H -68.4 -41.6 21.0 0.091 0.061 B:P08263:0.061
 GTX
HOH
 9.838
3.149
 O
OH
 N1
O
TYR B:95 B:95 32.0 0.139 H -67.6 -43.0 20.0 0.087 0.052 A:P08263:0.052
 GTX
HOH
 9.649
2.516
 O
OH
 N1
O
1xwg 1 P08263 94.57 5e-152 X-RAY
 2005-11-01 TYR A:94 A:95 34.0 0.148 H -62.2 -48.1 20.0 0.087 0.061 B:P08263:0.061
 HOH
 2.507
 OH
 O
TYR B:94 B:95 34.0 0.148 H -65.8 -44.9 21.0 0.091 0.057 A:P08263:0.057
 HOH
 2.654
 OH
 O
4hj2 1 P08263 94.93 4e-150 X-RAY
 2013-03-27 TYR A:92 A:95 39.0 0.17 H -68.4 -49.2 24.0 0.104 0.066 B:P08263:0.065
 LZ6
HOH
 9.590
5.900
 O
OH
 N38
O
TYR B:92 B:95 32.0 0.139 H -62.2 -56.5 20.0 0.087 0.052 A:P08263:0.052
 LZ6
HOH
 9.609
2.707
 O
OH
 N38
O
3i69 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 TYR A:95 A:95 30.0 0.13 H -68.2 -53.2 16.0 0.07 0.06 B:P08263:0.061
 HOH
 3.024
 OH
 O
TYR B:95 B:95 29.0 0.126 H -59.5 -50.1 18.0 0.078 0.048 A:P08263:0.048
 HOH
 2.739
 OH
 O
TYR C:95 C:95 26.0 0.113 H -66.6 -52.1 NA NA NA
TYR D:95 D:95 33.0 0.143 H -55.9 -51.7 NA NA NA
TYR E:95 E:95 35.0 0.152 H -65.3 -54.5 NA NA NA
TYR F:95 F:95 26.0 0.113 H -58.0 -56.6 NA NA NA
TYR G:95 G:95 30.0 0.13 H -63.5 -48.6 NA NA NA
TYR H:95 H:95 29.0 0.126 H -66.1 -51.6 NA NA NA
3i6a 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 TYR A:95 A:95 34.0 0.148 H -60.0 -53.5 20.0 0.087 0.061 B:P08263:0.061
 GSH
HOH
 9.507
2.704
 O
OH
 N1
O
TYR B:95 B:95 33.0 0.143 H -57.5 -49.1 20.0 0.087 0.056 A:P08263:0.057
 GSH
HOH
 9.519
2.527
 O
OH
 N1
O
TYR C:95 C:95 34.0 0.148 H -64.4 -45.9 NA NA NA
TYR D:95 D:95 32.0 0.139 H -62.2 -51.7 NA NA NA
TYR E:95 E:95 35.0 0.152 H -66.9 -46.6 NA NA NA
TYR F:95 F:95 33.0 0.143 H -64.0 -47.8 NA NA NA
TYR G:95 G:95 31.0 0.135 H -67.2 -50.0 NA NA NA
TYR H:95 H:95 32.0 0.139 H -68.8 -44.1 NA NA NA
3ik9 1 P08263 90.95 3e-145 X-RAY
 2010-06-23 TYR A:95 A:95 31.0 0.135 H -67.7 -53.2 20.0 0.087 0.048 B:P08263:0.048
 BOB
HOH
 9.603
8.608
 O
N
 N1
O
TYR B:95 B:95 32.0 0.139 H -54.8 -54.4 18.0 0.078 0.061 A:P08263:0.061
 BOB
HOH
 9.521
6.867
 O
CD2
 N1
O
TYR C:95 C:95 32.0 0.139 H -70.2 -49.8 NA NA NA
TYR D:95 D:95 36.0 0.157 H -57.0 -54.7 NA NA NA
TYR E:95 E:95 29.0 0.126 H -75.8 -55.2 NA NA NA
TYR F:95 F:95 28.0 0.122 H -69.4 -45.9 NA NA NA
TYR G:95 G:95 31.0 0.135 H -61.0 -49.2 NA NA NA
TYR H:95 H:95 31.0 0.135 H -66.9 -50.8 NA NA NA
1tdi 1 Q16772 88.74 4e-143 X-RAY
 2005-01-18 TYR A:95 A:95 38.0 0.165 H -66.3 -45.0 22.0 0.096 0.069 B:Q16772:0.07
 HOH
 2.626
 OH
 O
TYR B:95 B:95 34.0 0.148 H -66.2 -45.5 21.0 0.091 0.057 A:Q16772:0.057
 GSH
HOH
 9.918
2.705
 O
OH
 N1
O
2vcv 1 Q16772 88.74 4e-143 X-RAY
 2008-10-28 TYR A:95 A:95 35.0 0.152 H -57.1 -54.8 19.0 0.083 0.069 B:Q16772:0.07
 GSH
HOH
 9.635
2.621
 O
OH
 N1
O
TYR B:95 B:95 37.0 0.161 H -63.4 -51.1 21.0 0.091 0.07 A:Q16772:0.07
 GSH
HOH
 9.408
2.717
 O
OH
 N1
O
TYR C:95 C:95 40.0 0.174 H -63.6 -46.7 NA NA NA
TYR D:95 D:95 38.0 0.165 H -67.3 -44.8 NA NA NA
TYR E:95 E:95 32.0 0.139 H -52.9 -52.3 NA NA NA
TYR F:95 F:95 31.0 0.135 H -61.8 -51.5 NA NA NA
TYR G:95 G:95 35.0 0.152 H -54.6 -53.1 NA NA NA
TYR H:95 H:95 30.0 0.13 H -62.7 -53.0 NA NA NA
TYR I:95 I:95 41.0 0.178 H -61.1 -51.2 NA NA NA
TYR J:95 J:95 29.0 0.126 H -59.2 -52.7 NA NA NA
TYR K:95 K:95 34.0 0.148 H -61.3 -53.2 NA NA NA
TYR L:95 L:95 34.0 0.148 H -62.1 -51.4 NA NA NA
TYR M:95 M:95 38.0 0.165 H -60.4 -53.2 NA NA NA
TYR N:95 N:95 33.0 0.143 H -65.3 -46.2 NA NA NA
TYR O:95 O:95 35.0 0.152 H -64.3 -49.9 NA NA NA
TYR P:95 P:95 33.0 0.143 H -57.4 -50.4 NA NA NA
5lcz 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 TYR A:95 A:95 40.0 0.174 H -56.4 -48.9 19.0 0.083 0.091 B:P08263+P04903:0.091
 HOH
 3.423
 OH
 O
TYR B:95 B:95 36.0 0.157 H -61.5 -47.0 23.0 0.1 0.057 A:P08263+P04903:0.057
 GSH
HOH
 9.545
3.078
 O
OH
 N1
O
5ld0 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 TYR A:95 A:95 37.0 0.161 H -61.0 -47.3 23.0 0.1 0.061 A:P08263+P04903:0.061
 HOH
 2.569
 OH
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09210-f1 1 P09210 100.0 3e-163 TYR A:95 A:95 32.0 0.139 H -68.5 -47.9
af-p08263-f1 1 P08263 95.05 1e-154 TYR A:95 A:95 32.0 0.139 H -68.1 -47.5
af-q7rtv2-f1 1 Q7RTV2 88.74 1e-143 TYR A:95 A:95 31.0 0.135 H -69.4 -46.6
af-q16772-f1 1 Q16772 88.74 2e-143 TYR A:95 A:95 31.0 0.135 H -68.2 -48.6