Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52621070 . T A CCDS4944.1:NM_000846.4:c.125gAc>gTc_NP_000837.3:p.42D>V Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2vct 1 P09210 99.55 1e-162 X-RAY
 2008-10-28 ASP A:42 A:42 61.0 0.407 H -60.4 -31.9 61.0 0.407 0.0 HOH
 2.711
 OD2
 O
ASP B:42 B:42 39.0 0.26 H -57.0 -38.5 39.0 0.26 0.0 HOH
 3.530
 CB
 O
ASP C:42 C:42 61.0 0.407 H -60.4 -32.5 NA NA NA
ASP D:42 D:42 42.0 0.28 H -49.8 -39.9 NA NA NA
ASP E:42 E:42 47.0 0.313 H -58.0 -34.1 NA NA NA
ASP F:42 F:42 46.0 0.307 H -55.4 -29.8 NA NA NA
ASP G:42 G:42 36.0 0.24 H -63.7 -31.1 NA NA NA
ASP H:42 H:42 41.0 0.273 H -57.1 -29.6 NA NA NA
2wju 1 P09210 99.55 1e-162 X-RAY
 2009-06-09 ASP A:42 A:42 63.0 0.42 H -61.9 -31.1 63.0 0.42 0.0 GSH
HOH
 8.448
2.880
 OD1
OD2
 CA3
O
ASP B:42 B:42 45.0 0.3 H -54.1 -43.4 45.0 0.3 0.0 GSH
HOH
 8.990
7.582
 OD1
N
 O32
O
ASP C:42 C:42 52.0 0.347 H -55.5 -46.4 NA NA NA
ASP D:42 D:42 46.0 0.307 H -68.5 -34.7 NA NA NA
ASP E:42 E:42 39.0 0.26 H -55.6 -46.8 NA NA NA
ASP F:42 F:42 44.0 0.293 H -55.7 -27.5 NA NA NA
ASP G:42 G:42 66.0 0.44 H -72.5 -34.7 NA NA NA
ASP H:42 H:42 47.0 0.313 H -61.5 -33.6 NA NA NA
4acs 1 P09210 98.64 2e-158 X-RAY
 2011-12-28 ASP A:42 A:42 60.0 0.4 H -45.7 -40.4 60.0 0.4 0.0 GSH
HOH
 7.417
2.557
 OD1
OD1
 O31
O
ASP B:42 B:42 83.0 0.553 H -41.6 -41.2 83.0 0.553 0.0 GSH
HOH
 8.602
2.874
 OD1
OD2
 O31
O
ASP C:42 C:42 65.0 0.433 H -53.0 -43.3 NA NA NA
ASP D:42 D:42 76.0 0.507 H -42.6 -40.1 NA NA NA
1pkw 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 ASP A:42 A:42 56.0 0.373 H -68.1 -35.9 56.0 0.373 0.0 GSH
HOH
 8.136
3.913
 OD1
CB
 O32
O
ASP B:42 B:42 44.0 0.293 H -54.7 -39.9 44.0 0.293 0.0 GSH
HOH
 9.295
2.272
 OD1
OD1
 O32
O
1pkz 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 ASP A:42 A:42 72.0 0.48 H -58.8 -41.0 72.0 0.48 0.0 HOH
 2.823
 OD1
 O
ASP B:42 B:42 71.0 0.473 H -60.0 -37.7 71.0 0.473 0.0 HOH
 3.767
 O
 O
1pl1 1 P08263 95.05 4e-154 X-RAY
 2004-06-22 ASP A:42 A:42 58.0 0.387 H -64.8 -31.7 58.0 0.387 0.0 ABY
HOH
 7.887
2.909
 OD1
O
 O32
O
ASP B:42 B:42 39.0 0.26 H -62.2 -32.9 39.0 0.26 0.0 ABY
HOH
 8.083
3.970
 OD1
O
 O32
O
6yaw 1 P08263 95.05 4e-154 X-RAY
 2020-08-26 ASP A:42 A:42 48.0 0.32 H -66.8 -29.8 48.0 0.32 0.0 P9H
HOH
 8.418
6.058
 OD1
C
 O5
O
ASP B:42 B:42 58.0 0.387 H -68.4 -30.8 58.0 0.387 0.0 P9H
HOH
 8.120
8.560
 OD1
OD1
 O5
O
2r6k 1 P08263 94.59 5e-154 X-RAY
 2008-08-19 ASP A:42 A:42 39.0 0.26 H -67.1 -30.9 39.0 0.26 0.0 GTX
HOH
 7.928
3.933
 OD1
CB
 O31
O
ASP B:42 B:42 40.0 0.267 H -48.3 -34.0 40.0 0.267 0.0 GTX
HOH
 7.738
6.979
 OD1
C
 O31
O
3zfl 1 P08263 94.59 1e-153 X-RAY
 2012-12-19 ASP A:42 A:42 70.0 0.467 H -61.9 -39.1 70.0 0.467 0.0 HOH
 3.503
 OD1
 O
ASP B:42 B:42 77.0 0.513 H -58.8 -44.9 77.0 0.513 0.0 HOH
 4.236
 O
 O
3zfb 1 P08263 94.59 2e-153 X-RAY
 2012-12-19 ASP A:42 A:42 63.0 0.42 H -54.7 -43.1 63.0 0.42 0.0 HOH
 3.076
 OD1
 O
ASP B:42 B:42 75.0 0.5 H -58.2 -32.5 75.0 0.5 0.0 HOH
 3.564
 O
 O
1ydk 1 P08263 94.59 2e-153 X-RAY
 2005-06-07 ASP A:42 A:42 67.0 0.447 H -69.2 -33.3 67.0 0.447 0.0 GTX
HOH
 8.063
3.982
 OD1
CB
 O31
O
ASP B:42 B:42 42.0 0.28 H -52.1 -50.3 42.0 0.28 0.0 HOH
 2.828
 OD1
 O
3u6v 1 P08263 94.59 2e-153 X-RAY
 2011-10-26 ASP A:42 A:42 73.0 0.487 H -64.7 -39.8 73.0 0.487 0.0 HOH
 2.835
 OD1
 O
ASP B:42 B:42 70.0 0.467 H -54.9 -32.2 70.0 0.467 0.0 HOH
 6.131
 N
 O
1gsd 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 ASP A:41 A:42 65.0 0.433 H -69.5 -31.5 65.0 0.433 0.0 HOH
 6.326
 N
 O
ASP B:41 B:42 65.0 0.433 H -69.5 -31.5 65.0 0.433 0.0 HOH
 6.326
 N
 O
ASP C:41 C:42 65.0 0.433 H -69.5 -31.5 NA NA NA
ASP D:41 D:42 64.0 0.427 H -69.5 -31.6 NA NA NA
1gsf 1 P08263 95.02 2e-153 X-RAY
 1995-09-15 ASP A:41 A:42 56.0 0.373 H -73.9 -37.9 56.0 0.373 0.0 HOH
 8.909
 N
 O
ASP B:41 B:42 57.0 0.38 H -74.0 -37.8 57.0 0.38 0.0 HOH
 8.909
 N
 O
ASP C:41 C:42 56.0 0.373 H -73.9 -37.9 NA NA NA
ASP D:41 D:42 58.0 0.387 H -74.0 -37.8 NA NA NA
1guh 1 P08263 95.02 2e-153 X-RAY
 1993-10-31 ASP A:41 A:42 41.0 0.273 H -69.7 -29.6 41.0 0.273 0.0 GSB
 7.974
 OD1
 O31
ASP B:41 B:42 43.0 0.287 H -69.7 -29.5 43.0 0.287 0.0 GSB
 7.975
 OD1
 O31
ASP C:41 C:42 41.0 0.273 H -69.7 -29.5 NA NA NA
ASP D:41 D:42 41.0 0.273 H -69.7 -29.5 NA NA NA
1k3l 1 P08263 95.02 2e-153 X-RAY
 2002-10-23 ASP A:41 A:42 31.0 0.207 H -59.8 -35.6 31.0 0.207 0.0 GTX
HOH
 7.968
2.445
 OD1
OD2
 O31
O
ASP B:41 B:42 53.0 0.353 H -61.2 -34.1 53.0 0.353 0.0 GTX
HOH
 7.992
3.870
 OD1
CB
 O31
O
1k3o 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 ASP A:41 A:42 67.0 0.447 H -67.7 -40.6 67.0 0.447 0.0 HOH
 3.902
 CB
 O
ASP B:41 B:42 66.0 0.44 H -76.7 -31.6 66.0 0.44 0.0 HOH
 6.249
 N
 O
1k3y 1 P08263 95.02 2e-153 X-RAY
 2002-10-30 ASP A:41 A:42 41.0 0.273 H -61.6 -33.2 41.0 0.273 0.0 GTX
HOH
 7.916
2.731
 OD1
OD2
 O31
O
ASP B:41 B:42 42.0 0.28 H -67.2 -33.2 42.0 0.28 0.0 GTX
HOH
 7.956
2.698
 OD1
OD2
 O31
O
6ato 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 ASP A:41 A:42 41.0 0.273 H -61.4 -34.2 41.0 0.273 0.0 GSH
MPD
MPD
HOH
 8.169
5.438
9.591
3.086
 OD1
OD1
C
O
 O32
H51
H12
O
ASP B:41 B:42 60.0 0.4 H -67.3 -30.2 NA NA NA
6atp 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 ASP A:41 A:42 71.0 0.473 H -59.6 -40.5 71.0 0.473 0.0 MPD
HOH
 5.493
2.427
 O
OD1
 H32
O
ASP B:41 B:42 70.0 0.467 H -61.6 -44.1 NA NA NA
6atq 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 ASP A:41 A:42 63.0 0.42 H -54.6 -38.4 63.0 0.42 0.0 MES
HOH
 9.284
2.543
 OD1
OD1
 O1
O
ASP B:41 B:42 47.0 0.313 H -66.6 -36.8 NA NA NA
6atr 1 P08263 95.02 2e-153 X-RAY
 2018-09-12 ASP A:41 A:42 40.0 0.267 H -60.7 -35.5 40.0 0.267 0.0 BWS
GSN
EDO
HOH
 8.112
8.106
8.562
2.736
 OD1
OD1
O
OD2
 OAU
OAU
HO1
O
ASP B:41 B:42 43.0 0.287 H -60.9 -32.8 NA NA NA
1pl2 1 P08263 94.59 4e-153 X-RAY
 2004-06-22 ASP A:42 A:42 41.0 0.273 H -62.3 -34.6 41.0 0.273 0.0 ABY
HOH
 7.988
3.826
 OD1
CB
 O32
O
ASP B:42 B:42 41.0 0.273 H -62.1 -32.3 41.0 0.273 0.0 ABY
HOH
 8.145
3.911
 OD1
CB
 O32
O
1usb 1 P08263 95.02 5e-153 X-RAY
 2004-09-01 ASP A:45 A:42 73.0 0.487 H -54.0 -40.0 73.0 0.487 0.0 GSH
HOH
 8.621
4.611
 OD2
O
 O31
O
ASP B:45 B:42 67.0 0.447 H -61.1 -40.1 67.0 0.447 0.0 GSH
HOH
 9.104
3.161
 OD1
OD2
 O31
O
2r3x 1 P08263 94.59 6e-153 X-RAY
 2007-12-18 ASP A:42 A:42 32.0 0.213 H -57.1 -43.6 32.0 0.213 0.0 GTX
HOH
 8.040
2.833
 OD1
OD2
 O31
O
ASP B:42 B:42 44.0 0.293 H -63.8 -33.2 44.0 0.293 0.0 GTX
HOH
 7.954
3.475
 OD1
OD1
 O31
O
5jcu 1 P08263 95.02 8e-153 X-RAY
 2016-10-12 ASP A:41 A:42 48.0 0.32 H -63.2 -30.3 48.0 0.32 0.0 GVX
HOH
 8.276
3.801
 OD1
OD1
 O17
O
ASP B:41 B:42 47.0 0.313 H -63.0 -37.2 47.0 0.313 0.0 GVX
HOH
 8.196
3.538
 OD1
CB
 O18
O
ASP C:41 C:42 50.0 0.333 H -72.2 -31.8 NA NA NA
ASP D:41 D:42 41.0 0.273 H -53.7 -38.3 NA NA NA
1gse 1 P08263 94.57 9e-153 X-RAY
 1995-09-15 ASP A:41 A:42 56.0 0.373 H -64.8 -32.3 56.0 0.373 0.0 GSH
HOH
 8.192
3.804
 OD1
CB
 O32
O
ASP B:41 B:42 66.0 0.44 H -61.0 -34.2 66.0 0.44 0.0 GSH
HOH
 7.893
6.419
 OD1
C
 O32
O
3ktl 1 P08263 94.57 1e-152 X-RAY
 2009-12-22 ASP A:41 A:42 40.0 0.267 H -64.1 -28.5 40.0 0.267 0.0 GTX
HOH
 7.973
3.772
 OD1
CB
 O31
O
ASP B:41 B:42 44.0 0.293 H -59.7 -27.4 44.0 0.293 0.0 GTX
HOH
 8.012
2.497
 OD1
OD2
 O31
O
3q74 1 P08263 94.57 1e-152 X-RAY
 2011-01-12 ASP A:41 A:42 69.0 0.46 H -66.4 -37.0 69.0 0.46 0.0 HOH
 3.115
 OD1
 O
ASP B:41 B:42 70.0 0.467 H -57.0 -44.0 70.0 0.467 0.0 HOH
 2.720
 OD1
 O
3l0h 1 P08263 94.59 2e-152 X-RAY
 2010-01-12 ASP A:42 A:42 40.0 0.267 H -61.4 -37.9 40.0 0.267 0.0 GTX
HOH
 8.635
2.932
 OD1
OD1
 O31
O
ASP B:42 B:42 51.0 0.34 H -51.8 -37.5 51.0 0.34 0.0 GTX
HOH
 7.657
4.727
 OD1
CB
 O31
O
1xwg 1 P08263 94.57 5e-152 X-RAY
 2005-11-01 ASP A:41 A:42 72.0 0.48 H -64.1 -36.5 72.0 0.48 0.0 HOH
 2.640
 OD1
 O
ASP B:41 B:42 48.0 0.32 H -53.6 -37.0 48.0 0.32 0.0 HOH
 3.783
 CB
 O
4hj2 1 P08263 94.93 4e-150 X-RAY
 2013-03-27 ASP A:39 A:42 61.0 0.407 H -53.3 -29.9 61.0 0.407 0.0 LZ6
HOH
 7.960
5.963
 OD1
O
 O27
O
ASP B:39 B:42 62.0 0.413 H -66.3 -33.7 62.0 0.413 0.0 LZ6
HOH
 7.921
2.568
 OD2
OD1
 O27
O
3i69 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 ASP A:42 A:42 78.0 0.52 H -58.4 -28.6 78.0 0.52 0.0 HOH
 6.201
 C
 O
ASP B:42 B:42 72.0 0.48 H -57.7 -49.2 72.0 0.48 0.0 GSH
HOH
 9.254
3.147
 OD1
OD1
 O31
O
ASP C:42 C:42 82.0 0.547 H -74.0 -20.8 NA NA NA
ASP D:42 D:42 66.0 0.44 H -64.2 -36.0 NA NA NA
ASP E:42 E:42 65.0 0.433 H -56.8 -46.0 NA NA NA
ASP F:42 F:42 73.0 0.487 H -64.1 -32.6 NA NA NA
ASP G:42 G:42 68.0 0.453 H -65.5 -26.5 NA NA NA
ASP H:42 H:42 71.0 0.473 H -57.9 -38.0 NA NA NA
3i6a 1 P08263 90.95 3e-145 X-RAY
 2009-09-01 ASP A:42 A:42 79.0 0.527 H -62.6 -29.3 79.0 0.527 0.0 GSH
HOH
 8.364
3.083
 OD1
OD2
 O32
O
ASP B:42 B:42 75.0 0.5 H -61.5 -37.4 75.0 0.5 0.0 GSH
HOH
 9.190
2.962
 OD1
OD1
 O31
O
ASP C:42 C:42 69.0 0.46 H -67.0 -25.6 NA NA NA
ASP D:42 D:42 59.0 0.393 H -61.8 -28.1 NA NA NA
ASP E:42 E:42 65.0 0.433 H -57.2 -41.0 NA NA NA
ASP F:42 F:42 69.0 0.46 H -67.7 -34.1 NA NA NA
ASP G:42 G:42 67.0 0.447 H -55.2 -40.6 NA NA NA
ASP H:42 H:42 66.0 0.44 H -60.8 -43.1 NA NA NA
3ik9 1 P08263 90.95 3e-145 X-RAY
 2010-06-23 ASP A:42 A:42 77.0 0.513 H -64.8 -27.9 77.0 0.513 0.0 BOB
 8.169
 OD1
 CA3
ASP B:42 B:42 88.0 0.587 H -64.1 -29.0 88.0 0.587 0.0 BOB
HOH
 9.468
6.570
 OD1
C
 O31
O
ASP C:42 C:42 72.0 0.48 H -70.8 -28.3 NA NA NA
ASP D:42 D:42 70.0 0.467 H -57.1 -29.8 NA NA NA
ASP E:42 E:42 73.0 0.487 H -58.7 -39.4 NA NA NA
ASP F:42 F:42 74.0 0.493 H -55.8 -38.1 NA NA NA
ASP G:42 G:42 72.0 0.48 H -59.4 -43.9 NA NA NA
ASP H:42 H:42 69.0 0.46 H -63.0 -32.3 NA NA NA
1tdi 1 Q16772 88.74 4e-143 X-RAY
 2005-01-18 GLY A:42 A:42 20.0 0.267 H -57.8 -39.8 20.0 0.267 0.0 GSH
HOH
 9.599
3.696
 N
CA
 CA3
O
GLY B:42 B:42 18.0 0.24 H -52.4 -47.7 18.0 0.24 0.0 GSH
HOH
 9.458
3.929
 N
CA
 CA3
O
2vcv 1 Q16772 88.74 4e-143 X-RAY
 2008-10-28 GLY A:42 A:42 18.0 0.24 H -51.2 -41.2 18.0 0.24 0.0 GSH
HOH
 9.125
3.280
 N
CA
 O31
O
GLY B:42 B:42 23.0 0.307 H -50.2 -44.8 23.0 0.307 0.0 GSH
HOH
 9.384
4.747
 N
O
 O2
O
GLY C:42 C:42 26.0 0.347 H -62.5 -42.8 NA NA NA
GLY D:42 D:42 24.0 0.32 H -54.5 -40.0 NA NA NA
GLY E:42 E:42 19.0 0.253 H -63.0 -38.7 NA NA NA
GLY F:42 F:42 22.0 0.293 H -64.6 -34.1 NA NA NA
GLY G:42 G:42 23.0 0.307 H -56.7 -42.5 NA NA NA
GLY H:42 H:42 18.0 0.24 H -56.2 -43.6 NA NA NA
GLY I:42 I:42 22.0 0.293 H -50.6 -40.0 NA NA NA
GLY J:42 J:42 25.0 0.333 H -59.7 -37.3 NA NA NA
GLY K:42 K:42 21.0 0.28 H -59.5 -37.9 NA NA NA
GLY L:42 L:42 22.0 0.293 H -47.8 -48.2 NA NA NA
GLY M:42 M:42 21.0 0.28 H -54.5 -41.4 NA NA NA
GLY N:42 N:42 20.0 0.267 H -64.6 -39.8 NA NA NA
GLY O:42 O:42 20.0 0.267 H -52.6 -46.4 NA NA NA
GLY P:42 P:42 21.0 0.28 H -49.0 -41.5 NA NA NA
5lcz 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 ASP A:42 A:42 67.0 0.447 H -65.6 -33.5 67.0 0.447 0.0 GSH
HOH
 8.834
6.218
 OD1
N
 O32
O
ASP B:42 B:42 68.0 0.453 H -61.0 -47.5 68.0 0.453 0.0 HOH
 7.080
 O
 O
5ld0 1 P08263,P04903 80.63 3e-125 X-RAY
 2016-09-21 ASP A:42 A:42 73.0 0.487 H -63.3 -35.0 73.0 0.487 0.0 HOH
 2.627
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09210-f1 1 P09210 100.0 3e-163 ASP A:42 A:42 40.0 0.267 H -63.8 -33.3
af-p08263-f1 1 P08263 95.05 1e-154 ASP A:42 A:42 47.0 0.313 H -64.1 -33.3
af-q7rtv2-f1 1 Q7RTV2 88.74 1e-143 ASP A:42 A:42 44.0 0.293 H -63.6 -33.5
af-q16772-f1 1 Q16772 88.74 2e-143 GLY A:42 A:42 19.0 0.253 H -58.5 -40.7