Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52657686 . A C CCDS4945.1:NM_145740.3:c.514Tcc>Gcc_NP_665683.1:p.172S>A Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 SER A:172 A:172 88.0 0.765 T -64.2 -15.4 88.0 0.765 0.0 HOH
 2.698
 O
 O
SER B:172 B:172 87.0 0.757 T -71.9 -16.4 87.0 0.757 0.0 HOH
 2.790
 O
 O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 SER A:172 A:172 80.0 0.696 T -67.0 -21.0 80.0 0.696 0.0 HOH
 2.855
 O
 O
SER B:172 B:172 85.0 0.739 G -64.4 -22.8 85.0 0.739 0.0 HOH
 2.791
 O
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 SER A:172 A:172 89.0 0.774 T -70.3 -10.0 89.0 0.774 0.0 HOH
 2.767
 O
 O
SER B:172 B:172 88.0 0.765 T -71.5 -14.8 88.0 0.765 0.0 HOH
 2.465
 OG
 O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 SER A:172 A:172 80.0 0.696 G -67.0 -24.4 80.0 0.696 0.0 HOH
 6.583
 CB
 O
SER B:172 B:172 88.0 0.765 T -67.8 -10.4 88.0 0.765 0.0 HOH
 3.490
 CA
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 SER A:172 A:172 79.0 0.687 T -62.5 -4.3 79.0 0.687 0.0 HOH
 7.216
 N
 O
SER B:172 B:172 81.0 0.704 T -73.4 -15.8 81.0 0.704 0.0 HOH
 3.267
 O
 O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 SER A:172 A:172 81.0 0.704 T -79.4 0.0 81.0 0.704 0.0 HOH
 3.270
 N
 O
SER B:172 B:172 86.0 0.748 T -72.6 -10.8 86.0 0.748 0.0 HOH
 2.953
 O
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 SER A:172 A:172 80.0 0.696 T -76.2 -14.1 80.0 0.696 0.0 HOH
 3.421
 N
 O
SER B:172 B:172 89.0 0.774 T -77.2 -11.3 89.0 0.774 0.0 HOH
 3.467
 O
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 SER A:171 A:172 83.0 0.722 T -62.6 -16.3 83.0 0.722 0.0 HOH
 3.581
 O
 O
SER B:171 B:172 80.0 0.696 T -62.6 -16.3 80.0 0.696 0.0 HOH
 3.581
 O
 O
SER C:171 C:172 82.0 0.713 T -62.6 -16.3 NA NA NA
SER D:171 D:172 82.0 0.713 T -62.7 -16.3 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 SER A:171 A:172 86.0 0.748 T -61.5 -20.5 86.0 0.748 0.0 HOH
 4.916
 O
 O
SER B:171 B:172 85.0 0.739 T -61.5 -20.5 85.0 0.739 0.0 HOH
 4.916
 O
 O
SER C:171 C:172 86.0 0.748 T -61.5 -20.5 NA NA NA
SER D:171 D:172 84.0 0.73 T -61.5 -20.5 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 SER A:171 A:172 87.0 0.757 T -63.7 -6.5 87.0 0.757 0.0
SER B:171 B:172 88.0 0.765 T -63.7 -6.5 88.0 0.765 0.0
SER C:171 C:172 86.0 0.748 T -63.7 -6.5 NA NA NA
SER D:171 D:172 88.0 0.765 T -63.7 -6.6 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 SER A:171 A:172 86.0 0.748 T -68.4 -9.7 86.0 0.748 0.0 HOH
 2.925
 N
 O
SER B:171 B:172 89.0 0.774 T -66.5 -8.7 89.0 0.774 0.0 HOH
 2.784
 O
 O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 SER A:171 A:172 89.0 0.774 T -59.8 -22.9 89.0 0.774 0.0 HOH
 5.907
 O
 O
SER B:171 B:172 87.0 0.757 T -75.2 -3.1 87.0 0.757 0.0 HOH
 3.679
 O
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 SER A:171 A:172 88.0 0.765 T -74.1 -8.5 88.0 0.765 0.0 HOH
 2.939
 O
 O
SER B:171 B:172 88.0 0.765 T -66.0 -13.5 88.0 0.765 0.0 HOH
 2.964
 N
 O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 SER A:171 A:172 86.0 0.748 T -69.7 -10.9 86.0 0.748 0.0 HOH
 2.730
 O
 O
SER B:171 B:172 89.0 0.774 T -69.0 -10.5 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 SER A:171 A:172 92.0 0.8 T -68.6 -2.7 92.0 0.8 0.0 HOH
 2.763
 OG
 O
SER B:171 B:172 86.0 0.748 T -66.5 -11.9 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 SER A:171 A:172 85.0 0.739 G -65.0 -24.7 85.0 0.739 0.0 HOH
 3.076
 N
 O
SER B:171 B:172 83.0 0.722 T -70.0 -12.3 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 SER A:171 A:172 87.0 0.757 T -68.0 -12.8 87.0 0.757 0.0 EDO
HOH
 8.836
2.773
 N
OG
 H21
O
SER B:171 B:172 88.0 0.765 T -68.6 -11.8 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 SER A:172 A:172 84.0 0.73 T -70.7 -16.8 84.0 0.73 0.0 HOH
 2.528
 O
 O
SER B:172 B:172 86.0 0.748 T -93.8 -10.4 86.0 0.748 0.0 HOH
 2.764
 OG
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 SER A:172 A:172 89.0 0.774 T -65.7 -9.7 89.0 0.774 0.0 HOH
 2.676
 OG
 O
SER B:172 B:172 85.0 0.739 T -69.4 -16.0 85.0 0.739 0.0 HOH
 2.914
 O
 O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 SER A:172 A:172 89.0 0.774 T -70.1 -10.0 89.0 0.774 0.0 HOH
 2.632
 O
 O
SER B:172 B:172 86.0 0.748 T -70.3 -12.3 86.0 0.748 0.0 HOH
 2.763
 O
 O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 SER A:172 A:172 85.0 0.739 T -62.8 -14.8 85.0 0.739 0.0 HOH
 3.007
 O
 O
SER B:172 B:172 91.0 0.791 T -60.9 -19.1 91.0 0.791 0.0 HOH
 2.801
 N
 O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 SER A:171 A:172 80.0 0.696 T -67.3 -13.6 80.0 0.696 0.0 HOH
 3.003
 O
 O
SER B:171 B:172 80.0 0.696 T -66.3 -11.8 80.0 0.696 0.0 HOH
 2.951
 N
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 SER A:171 A:172 83.0 0.722 T -72.9 -18.2 83.0 0.722 0.0 HOH
 2.969
 N
 O
SER B:171 B:172 89.0 0.774 T -75.4 -3.2 89.0 0.774 0.0 HOH
 2.664
 O
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 SER A:171 A:172 84.0 0.73 T -62.7 -14.8 84.0 0.73 0.0 HOH
 2.815
 O
 O
SER B:171 B:172 87.0 0.757 T -64.4 -21.7 87.0 0.757 0.0 HOH
 2.904
 N
 O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 SER A:175 A:172 80.0 0.696 T -72.5 -19.1 80.0 0.696 0.0 HOH
 2.787
 O
 O
SER B:175 B:172 89.0 0.774 T -69.6 -17.4 89.0 0.774 0.0 HOH
 2.712
 O
 O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 SER A:172 A:172 83.0 0.722 T -76.8 -30.5 83.0 0.722 0.0 HOH
 3.042
 O
 O
SER B:172 B:172 91.0 0.791 T -64.8 -13.0 91.0 0.791 0.0 HOH
 2.928
 OG
 O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 SER A:171 A:172 93.0 0.809 T -69.0 -12.6 93.0 0.809 0.0 HOH
 3.030
 N
 O
SER B:171 B:172 88.0 0.765 T -69.8 -14.5 88.0 0.765 0.0 HOH
 2.704
 O
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 SER A:171 A:172 88.0 0.765 T -67.3 -14.7 88.0 0.765 0.0 EDO
HOH
 9.559
2.958
 N
O
 C1
O
SER B:171 B:172 88.0 0.765 T -68.3 -8.3 88.0 0.765 0.0 HOH
 2.681
 OG
 O
SER C:171 C:172 84.0 0.73 T -72.1 -15.3 NA NA NA
SER D:171 D:172 89.0 0.774 T -63.2 -6.1 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 SER A:169 A:172 88.0 0.765 T -71.3 0.0 88.0 0.765 0.0 HOH
 2.840
 OG
 O
SER B:169 B:172 81.0 0.704 T -64.6 -8.2 81.0 0.704 0.0 HOH
 2.890
 O
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 SER A:172 A:172 91.0 0.791 T -61.4 -21.0 91.0 0.791 0.0 HOH
 2.840
 OG
 O
SER B:172 B:172 92.0 0.8 T -64.9 -16.8 92.0 0.8 0.0 HOH
 3.105
 CB
 O
SER C:172 C:172 95.0 0.826 T -61.9 -13.7 NA NA NA
SER D:172 D:172 75.0 0.652 T -64.0 -17.7 NA NA NA
SER E:172 E:172 88.0 0.765 T -74.6 -9.8 NA NA NA
SER F:172 F:172 92.0 0.8 T -64.7 -19.4 NA NA NA
SER G:172 G:172 83.0 0.722 T -68.5 -7.6 NA NA NA
SER H:172 H:172 84.0 0.73 G -60.0 -23.3 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 SER A:172 A:172 90.0 0.783 T -68.7 -11.5 90.0 0.783 0.0 HOH
 2.932
 O
 O
SER B:172 B:172 90.0 0.783 G -63.6 -19.6 90.0 0.783 0.0 HOH
 3.198
 O
 O
SER C:172 C:172 90.0 0.783 T -69.5 -14.9 NA NA NA
SER D:172 D:172 82.0 0.713 T -72.4 -10.9 NA NA NA
SER E:172 E:172 85.0 0.739 T -71.4 -11.0 NA NA NA
SER F:172 F:172 92.0 0.8 T -72.7 -4.9 NA NA NA
SER G:172 G:172 89.0 0.774 T -69.0 -12.9 NA NA NA
SER H:172 H:172 74.0 0.643 T -71.4 -0.1 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 SER A:172 A:172 92.0 0.8 T -66.5 -9.7 92.0 0.8 0.0 HOH
 2.845
 O
 O
SER B:172 B:172 88.0 0.765 T -81.3 -2.7 88.0 0.765 0.0 HOH
 5.447
 O
 O
SER C:172 C:172 93.0 0.809 T -69.4 -5.9 NA NA NA
SER D:172 D:172 86.0 0.748 G -75.5 -15.3 NA NA NA
SER E:172 E:172 84.0 0.73 T -76.4 -6.3 NA NA NA
SER F:172 F:172 76.0 0.661 T -75.9 -3.6 NA NA NA
SER G:172 G:172 88.0 0.765 T -73.4 -0.0 NA NA NA
SER H:172 H:172 89.0 0.774 S -70.9 -20.4 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 SER A:172 A:172 89.0 0.774 T -65.5 -15.1 89.0 0.774 0.0 HOH
 2.863
 O
 O
SER B:172 B:172 84.0 0.73 T -72.7 -9.7 84.0 0.73 0.0 HOH
 5.535
 O
 O
SER C:172 C:172 86.0 0.748 T -68.6 -6.8 NA NA NA
SER D:172 D:172 85.0 0.739 T -70.8 -10.4 NA NA NA
SER E:172 E:172 83.0 0.722 T -71.0 -14.5 NA NA NA
SER F:172 F:172 87.0 0.757 T -65.4 -15.2 NA NA NA
SER G:172 G:172 90.0 0.783 T -73.4 -6.9 NA NA NA
SER H:172 H:172 83.0 0.722 T -71.8 -15.5 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 SER A:172 A:172 83.0 0.722 T -86.7 -6.7 83.0 0.722 0.0
SER B:172 B:172 81.0 0.704 T -74.0 -7.2 81.0 0.704 0.0 HOH
 5.278
 O
 O
SER C:172 C:172 82.0 0.713 T -66.1 -1.9 NA NA NA
SER D:172 D:172 82.0 0.713 T -73.1 -14.8 NA NA NA
SER E:172 E:172 80.0 0.696 T -76.0 -7.2 NA NA NA
SER F:172 F:172 76.0 0.661 T -76.7 -10.3 NA NA NA
SER G:172 G:172 84.0 0.73 T -85.6 -6.2 NA NA NA
SER H:172 H:172 92.0 0.8 S -74.0 -21.6 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 SER A:172 A:172 90.0 0.783 T -57.4 -20.1 90.0 0.783 0.0 HOH
 3.171
 OG
 O
SER B:172 B:172 93.0 0.809 T -57.6 -21.6 93.0 0.809 0.0 HOH
 2.291
 O
 O
SER C:172 C:172 98.0 0.852 T -60.2 -13.6 NA NA NA
SER D:172 D:172 92.0 0.8 T -54.6 -15.5 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 SER A:172 A:172 87.0 0.757 T -70.7 -3.7 87.0 0.757 0.0 HOH
 3.290
 N
 O
SER B:172 B:172 86.0 0.748 T -73.9 1.5 86.0 0.748 0.0 HOH
 3.205
 OG
 O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 SER A:172 A:172 83.0 0.722 T -77.4 -9.4 83.0 0.722 0.0 HOH
 2.527
 O
 O
SER B:172 B:172 86.0 0.748 T -75.3 -12.4 86.0 0.748 0.0 HOH
 2.818
 O
 O
SER C:172 C:172 90.0 0.783 T -80.7 -8.3 NA NA NA
SER D:172 D:172 84.0 0.73 T -74.2 -6.3 NA NA NA
SER E:172 E:172 88.0 0.765 T -73.5 -9.9 NA NA NA
SER F:172 F:172 85.0 0.739 T -65.0 -8.8 NA NA NA
SER G:172 G:172 86.0 0.748 T -67.6 -12.9 NA NA NA
SER H:172 H:172 86.0 0.748 T -83.3 -6.6 NA NA NA
SER I:172 I:172 84.0 0.73 T -78.4 -3.4 NA NA NA
SER J:172 J:172 87.0 0.757 T -76.7 -11.8 NA NA NA
SER K:172 K:172 88.0 0.765 T -69.5 -17.1 NA NA NA
SER L:172 L:172 87.0 0.757 T -67.4 -15.7 NA NA NA
SER M:172 M:172 85.0 0.739 T -81.9 -3.4 NA NA NA
SER N:172 N:172 82.0 0.713 T -68.0 -9.9 NA NA NA
SER O:172 O:172 86.0 0.748 T -74.1 -9.9 NA NA NA
SER P:172 P:172 81.0 0.704 T -76.9 -2.1 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 PRO A:172 A:172 86.0 0.593 G -57.2 -25.4 86.0 0.593 0.0 HOH
 6.474
 O
 O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 PRO A:172 B:172 87.0 0.6 G -62.6 -24.3 87.0 0.6 0.0 HOH
 6.442
 O
 O
PRO B:172 A:172 83.0 0.572 G -61.4 -26.1 83.0 0.572 0.0 HOH
 6.100
 O
 O
PRO C:172 D:172 86.0 0.593 G -62.1 -25.2 NA NA NA
PRO D:172 C:172 85.0 0.586 G -60.9 -25.6 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ALA A:172 A:172 54.0 0.47 T -64.1 -2.9 54.0 0.47 0.0 HOH
 6.923
 O
 O
ALA B:172 B:172 54.0 0.47 G -64.2 -20.3 54.0 0.47 0.0 HOH
 3.111
 N
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ALA A:172 A:172 55.0 0.478 G -60.3 -24.1 55.0 0.478 0.0 HOH
 2.629
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 SER A:172 A:172 77.0 0.67 G -58.3 -21.5
af-p09210-f1 1 P09210 95.05 1e-154 SER A:172 A:172 76.0 0.661 G -55.2 -22.8
af-q16772-f1 1 Q16772 90.54 2e-146 SER A:172 A:172 76.0 0.661 G -63.1 -19.7
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 SER A:172 A:172 85.0 0.739 G -61.3 -18.3