Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52657698 . C A CCDS4945.1:NM_145740.3:c.502Gag>Tag_NP_665683.1:p.168E>* Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 GLU A:168 A:168 95.0 0.5 H -54.1 -44.0 95.0 0.5 0.0 HOH
 2.744
 OE1
 O
GLU B:168 B:168 95.0 0.5 H -57.5 -41.4 95.0 0.5 0.0 HOH
 2.580
 OE1
 O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 GLU A:168 A:168 89.0 0.468 H -58.2 -47.1 89.0 0.468 0.0 HOH
 3.018
 OE1
 O
GLU B:168 B:168 91.0 0.479 H -58.8 -39.6 91.0 0.479 0.0 HOH
 2.494
 OE1
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 GLU A:168 A:168 93.0 0.489 H -56.6 -40.3 93.0 0.489 0.0 HOH
 2.646
 OE1
 O
GLU B:168 B:168 91.0 0.479 H -59.3 -39.0 91.0 0.479 0.0 HOH
 2.538
 OE1
 O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 GLU A:168 A:168 96.0 0.505 H -62.1 -43.6 96.0 0.505 0.0 HOH
 2.958
 OE1
 O
GLU B:168 B:168 89.0 0.468 H -56.2 -47.4 89.0 0.468 0.0 HOH
 3.726
 CA
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 GLU A:168 A:168 94.0 0.495 H -64.2 -51.5 94.0 0.495 0.0 HOH
 7.380
 O
 O
GLU B:168 B:168 92.0 0.484 H -53.8 -44.9 92.0 0.484 0.0 HOH
 2.644
 OE1
 O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 GLU A:168 A:168 88.0 0.463 H -57.1 -56.0 88.0 0.463 0.0 HOH
 3.107
 O
 O
GLU B:168 B:168 97.0 0.511 H -55.6 -40.6 97.0 0.511 0.0 HOH
 2.637
 O
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 GLU A:168 A:168 99.0 0.521 H -68.9 -48.6 99.0 0.521 0.0 HOH
 3.203
 OE1
 O
GLU B:168 B:168 90.0 0.474 H -62.5 -43.9 90.0 0.474 0.0 HOH
 2.933
 OE2
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 GLU A:167 A:168 78.0 0.411 H -59.8 -40.0 78.0 0.411 0.0 HOH
 2.626
 OE1
 O
GLU B:167 B:168 78.0 0.411 H -59.8 -40.0 78.0 0.411 0.0 HOH
 2.626
 OE1
 O
GLU C:167 C:168 77.0 0.405 H -59.8 -39.9 NA NA NA
GLU D:167 D:168 76.0 0.4 H -59.8 -40.0 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 GLU A:167 A:168 85.0 0.447 H -65.4 -42.1 85.0 0.447 0.0 HOH
 3.219
 CG
 O
GLU B:167 B:168 85.0 0.447 H -65.4 -42.1 85.0 0.447 0.0 HOH
 3.219
 CG
 O
GLU C:167 C:168 84.0 0.442 H -65.4 -42.2 NA NA NA
GLU D:167 D:168 86.0 0.453 H -65.3 -42.2 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 GLU A:167 A:168 87.0 0.458 H -66.9 -36.9 87.0 0.458 0.0
GLU B:167 B:168 88.0 0.463 H -66.9 -37.0 88.0 0.463 0.0
GLU C:167 C:168 86.0 0.453 H -66.9 -36.9 NA NA NA
GLU D:167 D:168 85.0 0.447 H -66.9 -36.9 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 GLU A:167 A:168 91.0 0.479 H -57.6 -39.9 91.0 0.479 0.0 HOH
 2.529
 OE1
 O
GLU B:167 B:168 94.0 0.495 H -59.7 -39.3 94.0 0.495 0.0 HOH
 2.659
 OE1
 O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 GLU A:167 A:168 101.0 0.532 H -56.1 -58.0 101.0 0.532 0.0 HOH
 2.569
 OE1
 O
GLU B:167 B:168 90.0 0.474 H -57.4 -43.9 90.0 0.474 0.0 HOH
 2.503
 OE1
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 GLU A:167 A:168 90.0 0.474 H -60.0 -39.8 90.0 0.474 0.0 HOH
 2.624
 OE2
 O
GLU B:167 B:168 95.0 0.5 H -58.7 -39.0 95.0 0.5 0.0 HOH
 2.677
 O
 O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLU A:167 A:168 92.0 0.484 H -62.2 -38.6 92.0 0.484 0.0 HOH
 2.607
 OE1
 O
GLU B:167 B:168 94.0 0.495 H -60.7 -41.6 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLU A:167 A:168 89.0 0.468 H -60.4 -44.8 89.0 0.468 0.0 HOH
 3.326
 N
 O
GLU B:167 B:168 94.0 0.495 H -59.8 -41.0 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLU A:167 A:168 91.0 0.479 H -62.8 -48.1 91.0 0.479 0.0 HOH
 3.408
 N
 O
GLU B:167 B:168 92.0 0.484 H -59.5 -42.2 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLU A:167 A:168 91.0 0.479 H -59.2 -38.6 91.0 0.479 0.0 EDO
HOH
 8.678
1.059
 N
OE1
 H11
O
GLU B:167 B:168 95.0 0.5 H -58.8 -39.6 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 GLU A:168 A:168 91.0 0.479 H -55.5 -51.8 91.0 0.479 0.0 HOH
 2.877
 OE1
 O
GLU B:168 B:168 95.0 0.5 H -56.4 -44.3 95.0 0.5 0.0 HOH
 2.464
 OE1
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 GLU A:168 A:168 90.0 0.474 H -62.1 -48.5 90.0 0.474 0.0 HOH
 2.488
 OE1
 O
GLU B:168 B:168 92.0 0.484 H -59.5 -45.8 92.0 0.484 0.0 HOH
 2.673
 OE1
 O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 GLU A:168 A:168 93.0 0.489 H -57.4 -41.9 93.0 0.489 0.0 HOH
 2.537
 OE2
 O
GLU B:168 B:168 96.0 0.505 H -57.7 -42.0 96.0 0.505 0.0 HOH
 2.540
 OE1
 O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 GLU A:168 A:168 91.0 0.479 H -63.8 -43.1 91.0 0.479 0.0 HOH
 2.626
 O
 O
GLU B:168 B:168 94.0 0.495 H -50.8 -47.6 94.0 0.495 0.0 HOH
 2.597
 OE1
 O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 GLU A:167 A:168 84.0 0.442 H -63.6 -45.1 84.0 0.442 0.0 HOH
 2.929
 OE1
 O
GLU B:167 B:168 90.0 0.474 H -63.5 -43.8 90.0 0.474 0.0 HOH
 2.761
 OE1
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 GLU A:167 A:168 95.0 0.5 H -53.1 -41.0 95.0 0.5 0.0 HOH
 2.499
 OE1
 O
GLU B:167 B:168 87.0 0.458 H -61.4 -39.6 87.0 0.458 0.0 HOH
 2.563
 OE2
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 GLU A:167 A:168 91.0 0.479 H -64.2 -42.7 91.0 0.479 0.0 HOH
 2.622
 OE1
 O
GLU B:167 B:168 96.0 0.505 H -61.5 -41.4 96.0 0.505 0.0 HOH
 2.576
 OE1
 O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 GLU A:171 A:168 79.0 0.416 H -70.4 -40.2 79.0 0.416 0.0 HOH
 2.339
 OE2
 O
GLU B:171 B:168 89.0 0.468 H -56.0 -44.5 89.0 0.468 0.0 HOH
 2.683
 OE1
 O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 GLU A:168 A:168 93.0 0.489 H -78.1 -40.0 93.0 0.489 0.0 HOH
 4.282
 CA
 O
GLU B:168 B:168 98.0 0.516 H -51.9 -43.2 98.0 0.516 0.0 HOH
 2.909
 OE1
 O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 GLU A:167 A:168 92.0 0.484 H -57.4 -44.5 92.0 0.484 0.0 HOH
 3.313
 N
 O
GLU B:167 B:168 94.0 0.495 H -55.8 -40.9 94.0 0.495 0.0 HOH
 2.621
 OE1
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 GLU A:167 A:168 93.0 0.489 H -61.9 -39.6 93.0 0.489 0.0 EDO
HOH
 6.474
2.675
 C
OE2
 C1
O
GLU B:167 B:168 91.0 0.479 H -60.5 -42.5 91.0 0.479 0.0 HOH
 2.614
 O
 O
GLU C:167 C:168 90.0 0.474 H -64.2 -41.9 NA NA NA
GLU D:167 D:168 87.0 0.458 H -69.9 -37.4 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 GLU A:165 A:168 87.0 0.458 H -64.3 -38.6 87.0 0.458 0.0 HOH
 2.822
 OE2
 O
GLU B:165 B:168 86.0 0.453 H -65.8 -45.2 86.0 0.453 0.0 HOH
 3.195
 CG
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 GLU A:168 A:168 98.0 0.516 H -64.4 -41.7 98.0 0.516 0.0 HOH
 2.349
 OE1
 O
GLU B:168 B:168 100.0 0.526 H -37.8 -47.3 100.0 0.526 0.0 HOH
 2.490
 OE1
 O
GLU C:168 C:168 103.0 0.542 H -62.8 -40.4 NA NA NA
GLU D:168 D:168 99.0 0.521 H -58.2 -49.6 NA NA NA
GLU E:168 E:168 91.0 0.479 H -60.5 -41.0 NA NA NA
GLU F:168 F:168 89.0 0.468 H -52.7 -50.8 NA NA NA
GLU G:168 G:168 103.0 0.542 H -63.4 -41.5 NA NA NA
GLU H:168 H:168 100.0 0.526 H -62.7 -42.4 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 GLU A:168 A:168 94.0 0.495 H -66.6 -41.3 94.0 0.495 0.0 HOH
 3.255
 CG
 O
GLU B:168 B:168 95.0 0.5 H -47.5 -38.2 95.0 0.5 0.0 HOH
 2.864
 OE1
 O
GLU C:168 C:168 92.0 0.484 H -47.8 -48.4 NA NA NA
GLU D:168 D:168 93.0 0.489 H -72.2 -37.3 NA NA NA
GLU E:168 E:168 93.0 0.489 H -58.4 -45.1 NA NA NA
GLU F:168 F:168 96.0 0.505 H -70.5 -42.0 NA NA NA
GLU G:168 G:168 97.0 0.511 H -50.9 -58.2 NA NA NA
GLU H:168 H:168 92.0 0.484 H -76.1 -10.6 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 GLU A:168 A:168 91.0 0.479 H -58.8 -45.1 91.0 0.479 0.0 HOH
 3.219
 N
 O
GLU B:168 B:168 90.0 0.474 H -49.6 -51.3 90.0 0.474 0.0 HOH
 3.629
 N
 O
GLU C:168 C:168 93.0 0.489 H -55.3 -48.5 NA NA NA
GLU D:168 D:168 96.0 0.505 H -47.2 -56.7 NA NA NA
GLU E:168 E:168 94.0 0.495 H -70.6 -35.0 NA NA NA
GLU F:168 F:168 94.0 0.495 H -69.4 -33.2 NA NA NA
GLU G:168 G:168 88.0 0.463 H -64.8 -37.7 NA NA NA
GLU H:168 H:168 87.0 0.458 H -65.0 -47.2 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 GLU A:168 A:168 92.0 0.484 H -56.5 -40.6 92.0 0.484 0.0 HOH
 2.555
 OE1
 O
GLU B:168 B:168 94.0 0.495 H -57.6 -49.4 94.0 0.495 0.0 HOH
 2.787
 OE1
 O
GLU C:168 C:168 92.0 0.484 H -53.6 -46.3 NA NA NA
GLU D:168 D:168 90.0 0.474 H -56.0 -40.6 NA NA NA
GLU E:168 E:168 91.0 0.479 H -57.0 -46.5 NA NA NA
GLU F:168 F:168 91.0 0.479 H -62.1 -41.0 NA NA NA
GLU G:168 G:168 93.0 0.489 H -54.5 -47.5 NA NA NA
GLU H:168 H:168 89.0 0.468 H -43.7 -59.0 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 GLU A:168 A:168 96.0 0.505 H -53.6 -40.1 96.0 0.505 0.0
GLU B:168 B:168 86.0 0.453 H -55.3 -49.6 86.0 0.453 0.0 HOH
 2.996
 N
 O
GLU C:168 C:168 81.0 0.426 H -56.2 -65.4 NA NA NA
GLU D:168 D:168 83.0 0.437 H -51.0 -47.9 NA NA NA
GLU E:168 E:168 84.0 0.442 H -62.3 -45.3 NA NA NA
GLU F:168 F:168 97.0 0.511 H -72.4 -37.3 NA NA NA
GLU G:168 G:168 87.0 0.458 H -57.3 -36.3 NA NA NA
GLU H:168 H:168 79.0 0.416 H -51.4 -45.6 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 GLU A:168 A:168 95.0 0.5 H -62.2 -35.3 95.0 0.5 0.0 HOH
 2.455
 OE2
 O
GLU B:168 B:168 88.0 0.463 H -62.9 -42.1 88.0 0.463 0.0 HOH
 2.517
 OE2
 O
GLU C:168 C:168 94.0 0.495 H -53.2 -56.2 NA NA NA
GLU D:168 D:168 88.0 0.463 H -61.9 -44.4 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 GLU A:168 A:168 92.0 0.484 H -59.2 -36.9 92.0 0.484 0.0 HOH
 2.688
 OE1
 O
GLU B:168 B:168 91.0 0.479 H -56.1 -40.8 91.0 0.479 0.0 HOH
 2.619
 OE1
 O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 GLU A:168 A:168 92.0 0.484 H -58.4 -41.9 92.0 0.484 0.0 HOH
 2.762
 OE1
 O
GLU B:168 B:168 85.0 0.447 H -60.8 -38.9 85.0 0.447 0.0 HOH
 2.566
 OE1
 O
GLU C:168 C:168 91.0 0.479 H -56.7 -38.4 NA NA NA
GLU D:168 D:168 92.0 0.484 H -65.3 -37.4 NA NA NA
GLU E:168 E:168 89.0 0.468 H -53.9 -39.8 NA NA NA
GLU F:168 F:168 90.0 0.474 H -53.8 -42.9 NA NA NA
GLU G:168 G:168 86.0 0.453 H -59.6 -41.3 NA NA NA
GLU H:168 H:168 90.0 0.474 H -63.2 -41.9 NA NA NA
GLU I:168 I:168 90.0 0.474 H -61.6 -38.4 NA NA NA
GLU J:168 J:168 90.0 0.474 H -61.1 -39.6 NA NA NA
GLU K:168 K:168 89.0 0.468 H -55.4 -41.3 NA NA NA
GLU L:168 L:168 91.0 0.479 H -63.4 -31.6 NA NA NA
GLU M:168 M:168 93.0 0.489 H -64.2 -36.7 NA NA NA
GLU N:168 N:168 89.0 0.468 H -61.4 -37.2 NA NA NA
GLU O:168 O:168 89.0 0.468 H -66.2 -36.9 NA NA NA
GLU P:168 P:168 84.0 0.442 H -66.5 -36.6 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 GLU A:168 A:168 70.0 0.368 H -63.2 -43.1 70.0 0.368 0.0 EDO
HOH
 8.531
2.630
 OE1
OE1
 O1
O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 GLU A:168 B:168 74.0 0.389 H -58.5 -39.8 74.0 0.389 0.0 HOH
 2.722
 OE1
 O
GLU B:168 A:168 74.0 0.389 H -57.2 -39.5 74.0 0.389 0.0 HOH
 2.658
 OE1
 O
GLU C:168 D:168 76.0 0.4 H -58.3 -40.2 NA NA NA
GLU D:168 C:168 73.0 0.384 H -57.8 -39.8 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 GLU A:168 A:168 86.0 0.453 H -56.2 -49.2 86.0 0.453 0.0 HOH
 2.822
 OE1
 O
GLU B:168 B:168 85.0 0.447 H -60.6 -45.3 85.0 0.447 0.0 HOH
 3.364
 O
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 GLU A:168 A:168 86.0 0.453 H -64.9 -36.3 86.0 0.453 0.0 HOH
 2.583
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 GLU A:168 A:168 78.0 0.411 H -67.4 -37.1
af-p09210-f1 1 P09210 95.05 1e-154 GLU A:168 A:168 78.0 0.411 H -65.8 -35.3
af-q16772-f1 1 Q16772 90.54 2e-146 GLU A:168 A:168 76.0 0.4 H -65.7 -37.6
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 GLU A:168 A:168 57.0 0.3 H -68.8 -35.4