Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52657767 . G A CCDS4945.1:NM_145740.3:c.433Caa>Taa_NP_665683.1:p.145Q>* Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 GLN A:145 A:145 70.0 0.389 -96.1 171.8 70.0 0.389 0.0 HOH
 2.648
 O
 O
GLN B:145 B:145 66.0 0.367 -94.4 162.7 66.0 0.367 0.0 HOH
 2.596
 O
 O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 GLN A:145 A:145 75.0 0.417 -91.2 173.2 75.0 0.417 0.0 HOH
 2.407
 O
 O
GLN B:145 B:145 73.0 0.406 -88.7 162.1 73.0 0.406 0.0 HOH
 2.749
 OE1
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 GLN A:145 A:145 75.0 0.417 -99.3 168.8 75.0 0.417 0.0 HOH
 2.676
 OE1
 O
GLN B:145 B:145 69.0 0.383 -99.2 161.7 69.0 0.383 0.0 HOH
 2.652
 OE1
 O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 GLN A:145 A:145 74.0 0.411 -102.7 166.4 74.0 0.411 0.0 HOH
 2.834
 OE1
 O
GLN B:145 B:145 68.0 0.378 -83.5 170.1 68.0 0.378 0.0 HOH
 2.475
 OE1
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 GLN A:145 A:145 76.0 0.422 -83.6 162.3 76.0 0.422 0.0 HOH
 2.947
 OE1
 O
GLN B:145 B:145 74.0 0.411 -98.4 167.1 74.0 0.411 0.0 HOH
 2.983
 NE2
 O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 GLN A:145 A:145 72.0 0.4 -92.6 167.1 72.0 0.4 0.0 HOH
 2.579
 O
 O
GLN B:145 B:145 65.0 0.361 -78.9 157.7 65.0 0.361 0.0 HOH
 2.557
 OE1
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 GLN A:145 A:145 75.0 0.417 -92.8 166.7 75.0 0.417 0.0 HOH
 2.876
 O
 O
GLN B:145 B:145 70.0 0.389 -82.1 168.6 70.0 0.389 0.0 HOH
 2.593
 O
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 GLN A:144 A:145 71.0 0.394 -96.9 165.5 71.0 0.394 0.0 HOH
 2.633
 OE1
 O
GLN B:144 B:145 72.0 0.4 -96.9 165.5 72.0 0.4 0.0 HOH
 2.634
 OE1
 O
GLN C:144 C:145 73.0 0.406 -96.8 165.5 NA NA NA
GLN D:144 D:145 74.0 0.411 -96.8 165.5 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 GLN A:144 A:145 70.0 0.389 -103.8 165.3 70.0 0.389 0.0 HOH
 2.694
 NE2
 O
GLN B:144 B:145 69.0 0.383 -103.9 165.3 69.0 0.383 0.0 HOH
 2.694
 NE2
 O
GLN C:144 C:145 68.0 0.378 -103.9 165.3 NA NA NA
GLN D:144 D:145 69.0 0.383 -103.9 165.3 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 GLN A:144 A:145 80.0 0.444 -92.9 170.9 80.0 0.444 0.0
GLN B:144 B:145 78.0 0.433 -92.9 170.9 78.0 0.433 0.0
GLN C:144 C:145 78.0 0.433 -92.9 170.9 NA NA NA
GLN D:144 D:145 76.0 0.422 -92.9 170.9 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 GLN A:144 A:145 72.0 0.4 -84.5 156.8 72.0 0.4 0.0 HOH
 2.581
 O
 O
GLN B:144 B:145 74.0 0.411 -78.4 158.4 74.0 0.411 0.0 HOH
 2.759
 OE1
 O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 GLN A:144 A:145 80.0 0.444 -85.9 162.8 80.0 0.444 0.0 HOH
 2.692
 OE1
 O
GLN B:144 B:145 85.0 0.472 -92.2 167.2 85.0 0.472 0.0 HOH
 3.338
 CB
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 GLN A:144 A:145 72.0 0.4 -97.1 152.9 72.0 0.4 0.0 HOH
 2.648
 OE1
 O
GLN B:144 B:145 71.0 0.394 -96.5 152.4 71.0 0.394 0.0 HOH
 2.624
 NE2
 O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLN A:144 A:145 73.0 0.406 -91.7 166.8 73.0 0.406 0.0 HOH
 2.652
 OE1
 O
GLN B:144 B:145 72.0 0.4 -91.8 164.3 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLN A:144 A:145 75.0 0.417 -92.7 168.4 75.0 0.417 0.0 HOH
 2.752
 O
 O
GLN B:144 B:145 67.0 0.372 -95.8 162.3 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLN A:144 A:145 74.0 0.411 -92.2 172.3 74.0 0.411 0.0 HOH
 2.633
 O
 O
GLN B:144 B:145 68.0 0.378 -91.4 164.7 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 GLN A:144 A:145 71.0 0.394 -97.1 165.2 71.0 0.394 0.0 HOH
 2.634
 O
 O
GLN B:144 B:145 71.0 0.394 -92.8 165.4 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 GLN A:145 A:145 72.0 0.4 -87.9 162.6 72.0 0.4 0.0 HOH
 2.608
 NE2
 O
GLN B:145 B:145 66.0 0.367 -98.6 160.2 66.0 0.367 0.0 HOH
 2.316
 OE1
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 GLN A:145 A:145 72.0 0.4 -89.9 162.1 72.0 0.4 0.0 HOH
 2.810
 OE1
 O
GLN B:145 B:145 70.0 0.389 -92.7 161.0 70.0 0.389 0.0 HOH
 2.675
 OE1
 O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 GLN A:145 A:145 74.0 0.411 -94.9 169.2 74.0 0.411 0.0 HOH
 2.706
 OE1
 O
GLN B:145 B:145 71.0 0.394 -95.9 162.1 71.0 0.394 0.0 HOH
 2.492
 O
 O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 GLN A:145 A:145 73.0 0.406 -89.9 164.4 73.0 0.406 0.0 HOH
 2.681
 O
 O
GLN B:145 B:145 71.0 0.394 -97.6 163.9 71.0 0.394 0.0 HOH
 2.561
 O
 O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 GLN A:144 A:145 75.0 0.417 -93.1 164.0 75.0 0.417 0.0 HOH
 2.760
 OE1
 O
GLN B:144 B:145 72.0 0.4 -91.6 164.8 72.0 0.4 0.0 HOH
 2.702
 OE1
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 GLN A:144 A:145 66.0 0.367 -95.7 162.5 66.0 0.367 0.0 HOH
 2.429
 O
 O
GLN B:144 B:145 74.0 0.411 -95.6 168.0 74.0 0.411 0.0 HOH
 2.613
 O
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 GLN A:144 A:145 72.0 0.4 -96.8 163.0 72.0 0.4 0.0 HOH
 2.536
 O
 O
GLN B:144 B:145 75.0 0.417 -90.9 157.7 75.0 0.417 0.0 HOH
 2.655
 O
 O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 GLN A:148 A:145 71.0 0.394 S -117.8 171.9 71.0 0.394 0.0 K
HOH
 8.294
2.628
 OE1
O
 K
O
GLN B:148 B:145 69.0 0.383 -108.6 168.2 69.0 0.383 0.0 K
HOH
 8.301
2.483
 OE1
O
 K
O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 GLN A:145 A:145 77.0 0.428 -95.1 161.1 77.0 0.428 0.0 HOH
 2.663
 O
 O
GLN B:145 B:145 75.0 0.417 -89.9 165.3 75.0 0.417 0.0 HOH
 2.688
 NE2
 O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 GLN A:144 A:145 75.0 0.417 -94.6 166.8 75.0 0.417 0.0 HOH
 2.749
 OE1
 O
GLN B:144 B:145 67.0 0.372 -92.9 159.7 67.0 0.372 0.0 HOH
 2.630
 O
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 GLN A:144 A:145 74.0 0.411 -101.6 167.6 74.0 0.411 0.0 HOH
 2.448
 OE1
 O
GLN B:144 B:145 72.0 0.4 -87.2 169.5 72.0 0.4 0.0 HOH
 2.413
 O
 O
GLN C:144 C:145 73.0 0.406 -93.1 167.5 NA NA NA
GLN D:144 D:145 77.0 0.428 -88.5 167.9 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 GLN A:142 A:145 76.0 0.422 -95.5 168.5 76.0 0.422 0.0 HOH
 2.610
 O
 O
GLN B:142 B:145 67.0 0.372 -99.4 161.7 67.0 0.372 0.0 HOH
 2.773
 OE1
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 GLN A:145 A:145 75.0 0.417 -88.3 169.9 75.0 0.417 0.0 HOH
 2.506
 O
 O
GLN B:145 B:145 70.0 0.389 -94.3 165.2 70.0 0.389 0.0 HOH
 2.362
 OE1
 O
GLN C:145 C:145 73.0 0.406 -95.7 167.6 NA NA NA
GLN D:145 D:145 74.0 0.411 -91.7 164.2 NA NA NA
GLN E:145 E:145 70.0 0.389 -96.4 171.7 NA NA NA
GLN F:145 F:145 68.0 0.378 -102.8 167.1 NA NA NA
GLN G:145 G:145 78.0 0.433 -90.3 167.3 NA NA NA
GLN H:145 H:145 84.0 0.467 -62.7 162.0 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 GLN A:145 A:145 72.0 0.4 -83.7 159.6 72.0 0.4 0.0 HOH
 4.020
 NE2
 O
GLN B:145 B:145 76.0 0.422 -95.0 164.7 76.0 0.422 0.0 HOH
 2.685
 OE1
 O
GLN C:145 C:145 71.0 0.394 -85.3 156.2 NA NA NA
GLN D:145 D:145 76.0 0.422 -112.1 160.6 NA NA NA
GLN E:145 E:145 70.0 0.389 -103.1 169.9 NA NA NA
GLN F:145 F:145 65.0 0.361 -98.6 172.4 NA NA NA
GLN G:145 G:145 57.0 0.317 -61.5 172.9 NA NA NA
GLN H:145 H:145 78.0 0.433 -109.3 177.0 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 GLN A:145 A:145 74.0 0.411 -99.0 162.8 74.0 0.411 0.0 HOH
 2.745
 O
 O
GLN B:145 B:145 72.0 0.4 -78.8 169.4 72.0 0.4 0.0 HOH
 2.474
 OE1
 O
GLN C:145 C:145 71.0 0.394 -93.0 160.1 NA NA NA
GLN D:145 D:145 78.0 0.433 -71.0 164.9 NA NA NA
GLN E:145 E:145 71.0 0.394 -74.5 164.6 NA NA NA
GLN F:145 F:145 87.0 0.483 -94.7 178.3 NA NA NA
GLN G:145 G:145 70.0 0.389 -90.2 159.6 NA NA NA
GLN H:145 H:145 76.0 0.422 -80.2 163.6 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 GLN A:145 A:145 73.0 0.406 -93.9 164.1 73.0 0.406 0.0 HOH
 2.644
 O
 O
GLN B:145 B:145 71.0 0.394 -93.3 162.6 71.0 0.394 0.0 HOH
 2.537
 OE1
 O
GLN C:145 C:145 71.0 0.394 -85.1 159.3 NA NA NA
GLN D:145 D:145 75.0 0.417 -94.2 163.9 NA NA NA
GLN E:145 E:145 76.0 0.422 -83.1 168.2 NA NA NA
GLN F:145 F:145 88.0 0.489 -88.1 172.3 NA NA NA
GLN G:145 G:145 77.0 0.428 -92.5 160.5 NA NA NA
GLN H:145 H:145 72.0 0.4 -94.9 161.9 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 GLN A:145 A:145 74.0 0.411 -81.7 161.9 74.0 0.411 0.0
GLN B:145 B:145 74.0 0.411 -81.2 166.7 74.0 0.411 0.0 HOH
 8.288
 OE1
 O
GLN C:145 C:145 71.0 0.394 -107.5 162.2 NA NA NA
GLN D:145 D:145 72.0 0.4 -111.2 168.0 NA NA NA
GLN E:145 E:145 65.0 0.361 -81.2 168.7 NA NA NA
GLN F:145 F:145 76.0 0.422 S -99.2 -176.1 NA NA NA
GLN G:145 G:145 71.0 0.394 -97.4 169.1 NA NA NA
GLN H:145 H:145 72.0 0.4 -71.9 172.4 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 GLN A:145 A:145 80.0 0.444 -82.2 160.5 80.0 0.444 0.0 HOH
 3.382
 OE1
 O
GLN B:145 B:145 67.0 0.372 -75.7 157.9 67.0 0.372 0.0 HOH
 2.515
 OE1
 O
GLN C:145 C:145 78.0 0.433 -86.4 172.7 NA NA NA
GLN D:145 D:145 69.0 0.383 -74.7 148.7 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 GLN A:145 A:145 71.0 0.394 -97.8 160.0 71.0 0.394 0.0 HOH
 2.816
 NE2
 O
GLN B:145 B:145 72.0 0.4 -104.5 165.4 72.0 0.4 0.0 HOH
 2.695
 O
 O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 GLN A:145 A:145 72.0 0.4 -95.4 163.9 72.0 0.4 0.0 HOH
 2.641
 NE2
 O
GLN B:145 B:145 74.0 0.411 -98.0 168.9 74.0 0.411 0.0 HOH
 2.642
 O
 O
GLN C:145 C:145 71.0 0.394 -102.4 164.6 NA NA NA
GLN D:145 D:145 69.0 0.383 -86.1 164.8 NA NA NA
GLN E:145 E:145 75.0 0.417 -98.7 168.5 NA NA NA
GLN F:145 F:145 77.0 0.428 -92.0 168.1 NA NA NA
GLN G:145 G:145 72.0 0.4 -84.2 161.8 NA NA NA
GLN H:145 H:145 70.0 0.389 -98.5 161.8 NA NA NA
GLN I:145 I:145 86.0 0.478 -91.8 164.1 NA NA NA
GLN J:145 J:145 70.0 0.389 -106.4 166.5 NA NA NA
GLN K:145 K:145 74.0 0.411 -99.3 163.3 NA NA NA
GLN L:145 L:145 70.0 0.389 -105.0 166.6 NA NA NA
GLN M:145 M:145 69.0 0.383 -95.6 166.4 NA NA NA
GLN N:145 N:145 70.0 0.389 -101.4 164.5 NA NA NA
GLN O:145 O:145 74.0 0.411 -84.3 164.1 NA NA NA
GLN P:145 P:145 70.0 0.389 -105.1 162.1 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 GLU A:145 A:145 77.0 0.405 -84.8 165.5 77.0 0.405 0.0 HOH
 2.333
 O
 O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 GLU A:145 B:145 74.0 0.389 -90.2 168.0 74.0 0.389 0.0 HOH
 2.718
 OE2
 O
GLU B:145 A:145 74.0 0.389 -89.1 168.7 74.0 0.389 0.0 HOH
 2.650
 OE2
 O
GLU C:145 D:145 75.0 0.395 -88.6 168.1 NA NA NA
GLU D:145 C:145 74.0 0.389 -89.6 168.0 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 GLN A:145 A:145 74.0 0.411 -71.5 171.1 74.0 0.411 0.0 HOH
 3.154
 NE2
 O
GLN B:145 B:145 67.0 0.372 -122.4 173.8 67.0 0.372 0.0 HOH
 2.744
 O
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 GLN A:145 A:145 70.0 0.389 -94.0 163.3 70.0 0.389 0.0 HOH
 2.716
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 GLN A:145 A:145 77.0 0.428 -104.8 169.0
af-p09210-f1 1 P09210 95.05 1e-154 GLN A:145 A:145 72.0 0.4 -105.2 170.8
af-q16772-f1 1 Q16772 90.54 2e-146 GLN A:145 A:145 74.0 0.411 -105.2 170.9
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 GLN A:145 A:145 72.0 0.4 -110.3 170.0