Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52659041 . A C CCDS4945.1:NM_145740.3:c.296aTa>aGa_NP_665683.1:p.99I>R Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:99 A:99 13.0 0.074 H -52.8 -41.8 13.0 0.074 0.0 HED
GSH
HOH
 3.859
8.575
3.887
 CG2
N
CG2
 S4
N1
O
ILE B:99 B:99 12.0 0.069 H -58.6 -39.2 12.0 0.069 0.0 GSH
HED
HOH
 8.458
3.833
3.997
 N
CG2
CG2
 N1
S3
O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:99 A:99 12.0 0.069 H -62.2 -42.0 12.0 0.069 0.0 HED
HOH
 3.957
3.980
 CG2
CG2
 S4
O
ILE B:99 B:99 11.0 0.063 H -63.8 -41.9 11.0 0.063 0.0 HED
HOH
 4.117
4.271
 CG2
CG2
 S4
O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:99 A:99 11.0 0.063 H -58.2 -45.2 11.0 0.063 0.0 ABY
HOH
 8.490
3.723
 N
CG2
 N1
O
ILE B:99 B:99 12.0 0.069 H -55.4 -47.8 12.0 0.069 0.0 ABY
HOH
 8.595
3.947
 N
CG2
 N1
O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 ILE A:99 A:99 12.0 0.069 H -59.9 -37.0 12.0 0.069 0.0 GOL
GOL
P9H
HOH
 8.668
9.971
8.335
4.137
 C
C
N
CG2
 O1
O2
N1
O
ILE B:99 B:99 12.0 0.069 H -57.6 -47.0 12.0 0.069 0.0 P9H
GOL
GOL
HOH
 8.535
9.523
8.778
4.022
 N
C
C
CG2
 N1
O2
O1
O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 ILE A:99 A:99 10.0 0.057 H -58.9 -47.2 10.0 0.057 0.0 GTX
HOH
 8.453
4.421
 N
CG2
 N1
O
ILE B:99 B:99 10.0 0.057 H -65.0 -46.6 10.0 0.057 0.0 GTX
HOH
 8.116
3.820
 N
CG2
 N1
O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 ILE A:99 A:99 10.0 0.057 H -57.9 -36.7 10.0 0.057 0.0 HOH
 3.658
 CG2
 O
ILE B:99 B:99 11.0 0.063 H -59.2 -42.9 11.0 0.063 0.0 HOH
 3.955
 CG2
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 ILE A:99 A:99 11.0 0.063 H -53.9 -49.1 11.0 0.063 0.0 HOH
 3.882
 CG2
 O
ILE B:99 B:99 12.0 0.069 H -57.6 -49.9 12.0 0.069 0.0 HOH
 3.720
 CG2
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ILE A:98 A:99 12.0 0.069 H -58.2 -42.6 12.0 0.069 0.0 HOH
 3.856
 CG2
 O
ILE B:98 B:99 11.0 0.063 H -58.2 -42.6 11.0 0.063 0.0 HOH
 3.856
 CG2
 O
ILE C:98 C:99 10.0 0.057 H -58.3 -42.5 NA NA NA
ILE D:98 D:99 10.0 0.057 H -58.2 -42.6 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ILE A:98 A:99 10.0 0.057 H -64.9 -44.1 10.0 0.057 0.0 HOH
 3.670
 CG2
 O
ILE B:98 B:99 10.0 0.057 H -64.9 -44.1 10.0 0.057 0.0 HOH
 3.671
 CG2
 O
ILE C:98 C:99 9.0 0.051 H -64.8 -44.1 NA NA NA
ILE D:98 D:99 10.0 0.057 H -64.8 -44.1 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 ILE A:98 A:99 11.0 0.063 H -62.0 -42.8 11.0 0.063 0.0 GSB
 8.564
 N
 N1
ILE B:98 B:99 11.0 0.063 H -62.0 -42.8 11.0 0.063 0.0 GSB
 8.485
 N
 N1
ILE C:98 C:99 11.0 0.063 H -62.0 -42.8 NA NA NA
ILE D:98 D:99 11.0 0.063 H -62.0 -42.8 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 ILE A:98 A:99 12.0 0.069 H -58.2 -44.0 12.0 0.069 0.0 GTX
HOH
 8.425
3.766
 N
CG2
 N1
O
ILE B:98 B:99 12.0 0.069 H -58.4 -43.4 12.0 0.069 0.0 GTX
HOH
 8.522
3.884
 N
CG2
 N1
O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ILE A:98 A:99 14.0 0.08 H -53.8 -41.5 14.0 0.08 0.0 HOH
 4.270
 CG2
 O
ILE B:98 B:99 12.0 0.069 H -60.6 -38.3 12.0 0.069 0.0 HOH
 4.316
 CG2
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ILE A:98 A:99 12.0 0.069 H -57.8 -43.7 12.0 0.069 0.0 GOL
GOL
GTX
GOL
HOH
 4.311
8.923
8.442
9.490
3.893
 CG2
C
N
C
CG2
 O1
O1
N1
O2
O
ILE B:98 B:99 13.0 0.074 H -57.0 -44.2 13.0 0.074 0.0 GTX
GOL
GOL
HOH
 8.502
9.588
8.942
3.889
 N
C
C
CG2
 N1
O2
O3
O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:98 A:99 11.0 0.063 H -59.9 -42.0 11.0 0.063 0.0 HOH
 3.742
 CG2
 O
ILE B:98 B:99 13.0 0.074 H -60.4 -38.4 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:98 A:99 11.0 0.063 H -60.9 -43.9 11.0 0.063 0.0 HOH
 3.657
 O
 O
ILE B:98 B:99 12.0 0.069 H -58.6 -43.6 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:98 A:99 12.0 0.069 H -56.3 -45.0 12.0 0.069 0.0 HOH
 3.743
 CG2
 O
ILE B:98 B:99 10.0 0.057 H -63.4 -39.2 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:98 A:99 12.0 0.069 H -56.0 -44.1 12.0 0.069 0.0 EDO
EDO
EDO
HOH
 3.244
5.420
8.874
3.678
 CG2
O
O
O
 HO1
O2
HO2
O
ILE B:98 B:99 13.0 0.074 H -56.7 -44.2 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 ILE A:99 A:99 11.0 0.063 H -57.8 -46.4 11.0 0.063 0.0 HOH
 3.416
 CG2
 O
ILE B:99 B:99 11.0 0.063 H -65.1 -39.6 11.0 0.063 0.0 HOH
 3.933
 CG2
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 ILE A:99 A:99 11.0 0.063 H -57.9 -46.1 11.0 0.063 0.0 GTX
HOH
 8.337
3.792
 N
CG2
 N1
O
ILE B:99 B:99 12.0 0.069 H -59.1 -43.2 12.0 0.069 0.0 GTX
HOH
 8.443
3.340
 N
O
 N1
O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 ILE A:99 A:99 12.0 0.069 H -57.6 -44.0 12.0 0.069 0.0 ABY
HOH
 8.413
3.619
 N
CG2
 N1
O
ILE B:99 B:99 12.0 0.069 H -56.3 -43.9 12.0 0.069 0.0 ABY
HOH
 8.519
3.701
 N
CG2
 N1
O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 ILE A:99 A:99 13.0 0.074 H -57.5 -47.5 13.0 0.074 0.0 GTX
HOH
 8.363
3.665
 N
CG2
 N1
O
ILE B:99 B:99 10.0 0.057 H -58.5 -44.6 10.0 0.057 0.0 GTX
HOH
 8.381
3.198
 N
CG2
 N1
O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 ILE A:98 A:99 12.0 0.069 H -60.7 -41.7 12.0 0.069 0.0 BME
BME
GSH
HOH
 3.809
5.791
8.456
3.808
 CG2
CG2
N
CG2
 S2
S2
N1
O
ILE B:98 B:99 12.0 0.069 H -63.7 -41.3 12.0 0.069 0.0 GSH
BME
BME
HOH
 8.474
3.841
5.760
3.960
 N
CG2
CG2
CG2
 N1
S2
S2
O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 ILE A:98 A:99 11.0 0.063 H -58.6 -42.2 11.0 0.063 0.0 HOH
 3.906
 CG2
 O
ILE B:98 B:99 12.0 0.069 H -52.6 -50.0 12.0 0.069 0.0 HOH
 3.772
 CG2
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 ILE A:98 A:99 10.0 0.057 H -58.7 -37.3 10.0 0.057 0.0 GTX
HOH
 8.478
3.178
 N
O
 N1
O
ILE B:98 B:99 11.0 0.063 H -54.8 -49.0 11.0 0.063 0.0 GTX
HOH
 8.574
3.471
 N
CG2
 N1
O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 ILE A:102 A:99 2.0 0.011 H -55.4 -49.1 2.0 0.011 0.0 CL
GSH
HOH
 7.605
8.403
4.435
 CD1
N
CG2
 CL
N1
O
ILE B:102 B:99 1.0 0.006 H -60.1 -46.7 1.0 0.006 0.0 GSH
CL
HOH
 8.371
7.480
4.050
 N
CG2
O
 N1
CL
O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 ILE A:99 A:99 12.0 0.069 H -62.8 -37.4 12.0 0.069 0.0 GTX
HOH
 8.459
3.383
 N
O
 N1
O
ILE B:99 B:99 11.0 0.063 H -58.4 -55.8 11.0 0.063 0.0 GTX
HOH
 8.428
3.793
 N
CG2
 N1
O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 ILE A:98 A:99 12.0 0.069 H -58.5 -43.5 12.0 0.069 0.0 HOH
 3.833
 CG2
 O
ILE B:98 B:99 12.0 0.069 H -58.0 -44.4 12.0 0.069 0.0 HOH
 3.686
 CG2
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 ILE A:98 A:99 13.0 0.074 H -58.9 -42.4 13.0 0.074 0.0 EDO
EDO
GVX
HOH
 5.356
4.062
8.424
4.010
 O
CG2
N
CG2
 O1
O2
N05
O
ILE B:98 B:99 11.0 0.063 H -62.1 -39.1 11.0 0.063 0.0 GVX
HOH
 8.413
3.457
 N
O
 N05
O
ILE C:98 C:99 14.0 0.08 H -60.0 -40.6 NA NA NA
ILE D:98 D:99 13.0 0.074 H -57.2 -44.3 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 ILE A:96 A:99 12.0 0.069 H -67.1 -40.4 12.0 0.069 0.0 LZ6
HOH
 8.234
4.019
 N
CG2
 N38
O
ILE B:96 B:99 13.0 0.074 H -62.0 -46.0 13.0 0.074 0.0 LZ6
HOH
 8.315
3.936
 N
CG2
 N38
O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 ILE A:99 A:99 7.0 0.04 H -58.1 -37.6 7.0 0.04 0.0 HOH
 3.796
 CG2
 O
ILE B:99 B:99 7.0 0.04 H -60.1 -46.6 7.0 0.04 0.0 HOH
 3.591
 CB
 O
ILE C:99 C:99 5.0 0.029 H -65.7 -48.3 NA NA NA
ILE D:99 D:99 7.0 0.04 H -61.3 -37.9 NA NA NA
ILE E:99 E:99 8.0 0.046 H -63.2 -42.1 NA NA NA
ILE F:99 F:99 9.0 0.051 H -58.9 -39.0 NA NA NA
ILE G:99 G:99 8.0 0.046 H -58.8 -43.3 NA NA NA
ILE H:99 H:99 10.0 0.057 H -62.4 -42.9 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 ILE A:99 A:99 8.0 0.046 H -57.8 -37.7 8.0 0.046 0.0 GSH
HOH
 8.194
5.889
 N
O
 N1
O
ILE B:99 B:99 10.0 0.057 H -70.4 -36.5 10.0 0.057 0.0 GSH
HOH
 8.441
3.867
 N
CG2
 N1
O
ILE C:99 C:99 9.0 0.051 H -60.8 -40.1 NA NA NA
ILE D:99 D:99 8.0 0.046 H -61.3 -41.6 NA NA NA
ILE E:99 E:99 9.0 0.051 H -59.4 -41.7 NA NA NA
ILE F:99 F:99 7.0 0.04 H -57.1 -45.4 NA NA NA
ILE G:99 G:99 9.0 0.051 H -60.7 -41.8 NA NA NA
ILE H:99 H:99 7.0 0.04 H -72.7 -34.5 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ILE A:99 A:99 11.0 0.063 H -63.1 -37.2 11.0 0.063 0.0 GSH
HOH
 9.031
3.985
 N
CG2
 N1
O
ILE B:99 B:99 11.0 0.063 H -65.5 -43.4 11.0 0.063 0.0 HOH
 4.046
 CG2
 O
ILE C:99 C:99 10.0 0.057 H -64.3 -35.1 NA NA NA
ILE D:99 D:99 12.0 0.069 H -57.6 -46.9 NA NA NA
ILE E:99 E:99 11.0 0.063 H -57.4 -42.8 NA NA NA
ILE F:99 F:99 12.0 0.069 H -52.7 -50.7 NA NA NA
ILE G:99 G:99 12.0 0.069 H -66.5 -42.3 NA NA NA
ILE H:99 H:99 7.0 0.04 H -55.7 -43.4 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ILE A:99 A:99 12.0 0.069 H -66.5 -44.6 12.0 0.069 0.0 GSH
HOH
 8.382
3.714
 N
CG2
 N1
O
ILE B:99 B:99 17.0 0.097 H -60.5 -36.4 17.0 0.097 0.0 GSH
HOH
 8.250
3.792
 N
CG2
 N1
O
ILE C:99 C:99 13.0 0.074 H -60.5 -42.7 NA NA NA
ILE D:99 D:99 16.0 0.091 H -63.9 -37.2 NA NA NA
ILE E:99 E:99 12.0 0.069 H -64.4 -44.5 NA NA NA
ILE F:99 F:99 16.0 0.091 H -60.5 -46.5 NA NA NA
ILE G:99 G:99 14.0 0.08 H -58.3 -43.7 NA NA NA
ILE H:99 H:99 13.0 0.074 H -58.9 -39.1 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 ILE A:99 A:99 9.0 0.051 H -66.6 -45.7 9.0 0.051 0.0 BOB
HOH
 8.426
7.547
 N
CG2
 N1
O
ILE B:99 B:99 14.0 0.08 H -69.3 -43.0 14.0 0.08 0.0 BOB
HOH
 8.264
4.142
 N
CG2
 N1
O
ILE C:99 C:99 12.0 0.069 H -59.2 -47.4 NA NA NA
ILE D:99 D:99 15.0 0.086 H -62.5 -46.1 NA NA NA
ILE E:99 E:99 11.0 0.063 H -66.5 -44.0 NA NA NA
ILE F:99 F:99 15.0 0.086 H -56.3 -48.2 NA NA NA
ILE G:99 G:99 13.0 0.074 H -60.5 -52.1 NA NA NA
ILE H:99 H:99 12.0 0.069 H -60.2 -52.3 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 ILE A:99 A:99 10.0 0.057 H -62.1 -45.8 10.0 0.057 0.0 GSH
HOH
 8.284
3.371
 N
CB
 N1
O
ILE B:99 B:99 9.0 0.051 H -55.7 -33.3 9.0 0.051 0.0 GSH
HOH
 8.332
3.709
 N
CG2
 N1
O
ILE C:99 C:99 11.0 0.063 H -60.2 -44.6 NA NA NA
ILE D:99 D:99 8.0 0.046 H -66.2 -36.5 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 MET A:99 A:99 7.0 0.038 H -56.5 -42.4 7.0 0.038 0.0 GSH
HOH
 8.537
5.431
 N
CB
 N1
O
MET B:99 B:99 6.0 0.032 H -64.5 -41.5 6.0 0.032 0.0 GSH
HOH
 8.417
4.283
 N
CB
 N1
O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 MET A:99 A:99 6.0 0.032 H -59.4 -41.8 6.0 0.032 0.0 GSH
HOH
 8.457
3.770
 N
CB
 N1
O
MET B:99 B:99 4.0 0.022 H -63.9 -34.7 4.0 0.022 0.0 GSH
HOH
 8.188
3.555
 N
CB
 N1
O
MET C:99 C:99 2.0 0.011 H -68.4 -40.5 NA NA NA
MET D:99 D:99 5.0 0.027 H -61.3 -41.8 NA NA NA
MET E:99 E:99 5.0 0.027 H -59.0 -37.6 NA NA NA
MET F:99 F:99 5.0 0.027 H -58.8 -40.4 NA NA NA
MET G:99 G:99 2.0 0.011 H -56.7 -47.2 NA NA NA
MET H:99 H:99 7.0 0.038 H -60.9 -34.8 NA NA NA
MET I:99 I:99 7.0 0.038 H -61.5 -46.9 NA NA NA
MET J:99 J:99 7.0 0.038 H -58.7 -47.5 NA NA NA
MET K:99 K:99 6.0 0.032 H -59.8 -42.7 NA NA NA
MET L:99 L:99 6.0 0.032 H -53.1 -45.0 NA NA NA
MET M:99 M:99 4.0 0.022 H -62.1 -43.7 NA NA NA
MET N:99 N:99 6.0 0.032 H -59.6 -38.0 NA NA NA
MET O:99 O:99 6.0 0.032 H -61.2 -48.0 NA NA NA
MET P:99 P:99 5.0 0.027 H -56.0 -42.8 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 VAL A:99 A:99 10.0 0.065 H -56.8 -46.7 10.0 0.065 0.0 EDO
GSH
HOH
 4.042
8.463
3.698
 CG1
N
CG1
 C2
N1
O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 VAL A:99 B:99 11.0 0.071 H -52.9 -44.5 11.0 0.071 0.0 GSH
HOH
 8.381
5.682
 N
O
 N1
O
VAL B:99 A:99 11.0 0.071 H -52.7 -45.1 11.0 0.071 0.0 GSH
HOH
 8.428
3.731
 N
CG1
 N1
O
VAL C:99 D:99 10.0 0.065 H -52.1 -45.1 NA NA NA
VAL D:99 C:99 9.0 0.058 H -52.8 -44.2 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ILE A:99 A:99 5.0 0.029 H -55.4 -39.8 5.0 0.029 0.0 HOH
 3.681
 CG2
 O
ILE B:99 B:99 3.0 0.017 H -51.9 -45.4 3.0 0.017 0.0 GSH
HOH
 8.499
3.513
 N
CG2
 N1
O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ILE A:99 A:99 2.0 0.011 H -61.9 -45.1 2.0 0.011 0.0 HOH
 3.739
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 ILE A:99 A:99 12.0 0.069 H -65.5 -41.8
af-p09210-f1 1 P09210 95.05 1e-154 ILE A:99 A:99 11.0 0.063 H -65.3 -42.9
af-q16772-f1 1 Q16772 90.54 2e-146 MET A:99 A:99 5.0 0.027 H -67.1 -40.6
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 ILE A:99 A:99 0.0 0.0 H -69.5 -41.6