Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52661028 . A C CCDS4945.1:NM_145740.3:c.224aTt>aGt_NP_665683.1:p.75I>S Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:75 A:75 0.0 0.0 H -61.4 -43.8 0.0 0.0 0.0 HOH
 5.839
 N
 O
ILE B:75 B:75 1.0 0.006 H -62.1 -47.4 1.0 0.006 0.0 HOH
 5.763
 N
 O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:75 A:75 1.0 0.006 H -56.0 -46.4 1.0 0.006 0.0 HOH
 5.836
 N
 O
ILE B:75 B:75 0.0 0.0 H -60.0 -46.1 0.0 0.0 0.0 HOH
 5.710
 N
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:75 A:75 0.0 0.0 H -57.6 -44.5 0.0 0.0 0.0 HOH
 5.779
 N
 O
ILE B:75 B:75 1.0 0.006 H -61.4 -43.4 1.0 0.006 0.0 HOH
 5.773
 N
 O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 ILE A:75 A:75 1.0 0.006 H -64.9 -42.1 1.0 0.006 0.0 HOH
 5.870
 N
 O
ILE B:75 B:75 1.0 0.006 H -61.1 -36.6 1.0 0.006 0.0 HOH
 5.705
 N
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 ILE A:75 A:75 1.0 0.006 H -58.3 -43.7 1.0 0.006 0.0 HOH
 5.833
 N
 O
ILE B:75 B:75 1.0 0.006 H -52.5 -44.5 1.0 0.006 0.0 HOH
 7.109
 O
 O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 ILE A:75 A:75 2.0 0.011 H -64.8 -39.1 2.0 0.011 0.0 HOH
 5.825
 N
 O
ILE B:75 B:75 2.0 0.011 H -61.6 -46.4 2.0 0.011 0.0 HOH
 6.957
 O
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 ILE A:75 A:75 4.0 0.023 H -63.6 -43.6 4.0 0.023 0.0 HOH
 6.080
 N
 O
ILE B:75 B:75 7.0 0.04 H -67.0 -39.7 7.0 0.04 0.0 HOH
 5.675
 N
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ILE A:74 A:75 1.0 0.006 H -57.7 -47.8 1.0 0.006 0.0 HOH
 5.762
 N
 O
ILE B:74 B:75 0.0 0.0 H -57.7 -47.8 0.0 0.0 0.0 HOH
 5.727
 N
 O
ILE C:74 C:75 0.0 0.0 H -57.7 -47.8 NA NA NA
ILE D:74 D:75 1.0 0.006 H -57.7 -47.9 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ILE A:74 A:75 1.0 0.006 H -53.3 -56.5 1.0 0.006 0.0 HOH
 5.701
 N
 O
ILE B:74 B:75 1.0 0.006 H -53.3 -56.5 1.0 0.006 0.0 HOH
 5.650
 N
 O
ILE C:74 C:75 1.0 0.006 H -53.3 -56.4 NA NA NA
ILE D:74 D:75 1.0 0.006 H -53.3 -56.6 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 ILE A:74 A:75 0.0 0.0 H -57.3 -47.9 0.0 0.0 0.0
ILE B:74 B:75 0.0 0.0 H -57.3 -47.8 0.0 0.0 0.0
ILE C:74 C:75 0.0 0.0 H -57.2 -47.9 NA NA NA
ILE D:74 D:75 0.0 0.0 H -57.3 -47.8 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 ILE A:74 A:75 0.0 0.0 H -60.4 -44.1 0.0 0.0 0.0 HOH
 5.705
 N
 O
ILE B:74 B:75 1.0 0.006 H -59.8 -44.0 1.0 0.006 0.0 HOH
 5.720
 N
 O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ILE A:74 A:75 2.0 0.011 H -64.1 -40.9 2.0 0.011 0.0 HOH
 6.139
 N
 O
ILE B:74 B:75 2.0 0.011 H -53.7 -48.3 2.0 0.011 0.0 HOH
 5.530
 N
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ILE A:74 A:75 0.0 0.0 H -61.2 -41.9 0.0 0.0 0.0 HOH
 5.766
 N
 O
ILE B:74 B:75 0.0 0.0 H -61.0 -45.7 0.0 0.0 0.0 HOH
 5.731
 N
 O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:74 A:75 1.0 0.006 H -59.1 -43.2 1.0 0.006 0.0 HOH
 6.194
 N
 O
ILE B:74 B:75 1.0 0.006 H -59.2 -45.7 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:74 A:75 1.0 0.006 H -59.4 -45.5 1.0 0.006 0.0 HOH
 6.112
 N
 O
ILE B:74 B:75 1.0 0.006 H -61.3 -47.3 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:74 A:75 1.0 0.006 H -56.8 -42.8 1.0 0.006 0.0 HOH
 6.216
 N
 O
ILE B:74 B:75 1.0 0.006 H -57.5 -49.4 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:74 A:75 1.0 0.006 H -60.3 -45.1 1.0 0.006 0.0 EDO
EDO
HOH
 9.865
8.500
6.203
 CB
CG1
N
 H22
H22
O
ILE B:74 B:75 0.0 0.0 H -60.4 -43.8 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 ALA A:75 A:75 4.0 0.035 H -60.8 -41.9 4.0 0.035 0.0 HOH
 5.870
 N
 O
ALA B:75 B:75 4.0 0.035 H -69.1 -44.7 4.0 0.035 0.0 HOH
 5.770
 N
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 ILE A:75 A:75 1.0 0.006 H -57.4 -45.7 1.0 0.006 0.0 HOH
 5.844
 N
 O
ILE B:75 B:75 0.0 0.0 H -61.6 -46.5 0.0 0.0 0.0 HOH
 5.758
 N
 O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 ILE A:75 A:75 0.0 0.0 H -58.6 -44.2 0.0 0.0 0.0 HOH
 5.790
 N
 O
ILE B:75 B:75 1.0 0.006 H -62.7 -45.6 1.0 0.006 0.0 HOH
 5.763
 N
 O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 ILE A:75 A:75 0.0 0.0 H -55.5 -50.0 0.0 0.0 0.0 HOH
 5.763
 N
 O
ILE B:75 B:75 0.0 0.0 H -60.5 -44.7 0.0 0.0 0.0 HOH
 5.655
 N
 O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 ILE A:74 A:75 1.0 0.006 H -58.3 -43.4 1.0 0.006 0.0 HOH
 6.004
 N
 O
ILE B:74 B:75 1.0 0.006 H -59.7 -44.5 1.0 0.006 0.0 HOH
 5.789
 N
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 ILE A:74 A:75 1.0 0.006 H -51.7 -50.5 1.0 0.006 0.0 HOH
 5.776
 N
 O
ILE B:74 B:75 1.0 0.006 H -53.6 -48.6 1.0 0.006 0.0 HOH
 5.862
 N
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 ILE A:74 A:75 0.0 0.0 H -53.8 -48.4 0.0 0.0 0.0 HOH
 5.730
 N
 O
ILE B:74 B:75 0.0 0.0 H -50.7 -45.1 0.0 0.0 0.0 HOH
 5.627
 N
 O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 ILE A:78 A:75 0.0 0.0 H -54.1 -49.7 0.0 0.0 0.0 CL
HOH
 7.800
5.840
 CG2
N
 CL
O
ILE B:78 B:75 0.0 0.0 H -58.6 -47.6 0.0 0.0 0.0 CL
HOH
 7.986
5.783
 CB
N
 CL
O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 ILE A:75 A:75 1.0 0.006 H -72.7 -40.7 1.0 0.006 0.0 HOH
 5.907
 N
 O
ILE B:75 B:75 2.0 0.011 H -44.7 -39.6 2.0 0.011 0.0 HOH
 5.981
 N
 O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 ILE A:74 A:75 1.0 0.006 H -56.2 -44.0 1.0 0.006 0.0 HOH
 5.936
 N
 O
ILE B:74 B:75 1.0 0.006 H -64.2 -44.5 1.0 0.006 0.0 HOH
 5.873
 N
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 ILE A:74 A:75 1.0 0.006 H -61.5 -44.5 1.0 0.006 0.0 HOH
 5.676
 N
 O
ILE B:74 B:75 1.0 0.006 H -59.8 -45.4 1.0 0.006 0.0 HOH
 5.698
 N
 O
ILE C:74 C:75 1.0 0.006 H -60.8 -47.9 NA NA NA
ILE D:74 D:75 0.0 0.0 H -58.8 -42.7 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 ILE A:72 A:75 3.0 0.017 H -61.8 -46.3 3.0 0.017 0.0 HOH
 5.715
 N
 O
ILE B:72 B:75 0.0 0.0 H -58.6 -42.3 0.0 0.0 0.0 HOH
 5.736
 N
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 ILE A:75 A:75 0.0 0.0 H -59.2 -53.9 0.0 0.0 0.0 HOH
 5.780
 N
 O
ILE B:75 B:75 0.0 0.0 H -56.3 -46.4 0.0 0.0 0.0 HOH
 5.979
 N
 O
ILE C:75 C:75 1.0 0.006 H -63.1 -45.8 NA NA NA
ILE D:75 D:75 0.0 0.0 H -55.6 -42.8 NA NA NA
ILE E:75 E:75 0.0 0.0 H -52.9 -48.0 NA NA NA
ILE F:75 F:75 0.0 0.0 H -56.9 -41.9 NA NA NA
ILE G:75 G:75 1.0 0.006 H -57.7 -42.2 NA NA NA
ILE H:75 H:75 0.0 0.0 H -65.5 -44.6 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 ILE A:75 A:75 1.0 0.006 H -64.8 -43.3 1.0 0.006 0.0 HOH
 5.907
 N
 O
ILE B:75 B:75 1.0 0.006 H -62.6 -47.1 1.0 0.006 0.0 HOH
 5.891
 N
 O
ILE C:75 C:75 0.0 0.0 H -65.6 -44.9 NA NA NA
ILE D:75 D:75 1.0 0.006 H -81.0 -40.5 NA NA NA
ILE E:75 E:75 0.0 0.0 H -67.7 -39.7 NA NA NA
ILE F:75 F:75 2.0 0.011 H -45.8 -41.8 NA NA NA
ILE G:75 G:75 0.0 0.0 H -61.9 -35.8 NA NA NA
ILE H:75 H:75 1.0 0.006 H -54.3 -48.8 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ILE A:75 A:75 1.0 0.006 H -63.4 -49.6 1.0 0.006 0.0 HOH
 5.828
 N
 O
ILE B:75 B:75 0.0 0.0 H -65.2 -32.6 0.0 0.0 0.0 HOH
 5.863
 N
 O
ILE C:75 C:75 3.0 0.017 H -51.3 -58.3 NA NA NA
ILE D:75 D:75 0.0 0.0 H -59.9 -40.4 NA NA NA
ILE E:75 E:75 3.0 0.017 H -71.7 -46.2 NA NA NA
ILE F:75 F:75 2.0 0.011 H -59.1 -45.0 NA NA NA
ILE G:75 G:75 1.0 0.006 H -65.6 -41.0 NA NA NA
ILE H:75 H:75 1.0 0.006 H -68.1 -35.9 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ILE A:75 A:75 1.0 0.006 H -62.4 -49.9 1.0 0.006 0.0 HOH
 5.813
 N
 O
ILE B:75 B:75 1.0 0.006 H -60.5 -48.0 1.0 0.006 0.0 HOH
 5.717
 N
 O
ILE C:75 C:75 2.0 0.011 H -61.3 -46.8 NA NA NA
ILE D:75 D:75 1.0 0.006 H -51.6 -50.0 NA NA NA
ILE E:75 E:75 1.0 0.006 H -59.8 -46.8 NA NA NA
ILE F:75 F:75 0.0 0.0 H -54.9 -46.4 NA NA NA
ILE G:75 G:75 1.0 0.006 H -65.3 -43.6 NA NA NA
ILE H:75 H:75 0.0 0.0 H -65.1 -43.6 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 ILE A:75 A:75 1.0 0.006 H -64.6 -52.7 1.0 0.006 0.0 HOH
 7.380
 CD1
 O
ILE B:75 B:75 0.0 0.0 H -64.7 -48.0 0.0 0.0 0.0 HOH
 7.215
 CD1
 O
ILE C:75 C:75 1.0 0.006 H -71.2 -43.4 NA NA NA
ILE D:75 D:75 1.0 0.006 H -63.1 -45.1 NA NA NA
ILE E:75 E:75 0.0 0.0 H -55.5 -49.5 NA NA NA
ILE F:75 F:75 0.0 0.0 H -63.4 -42.6 NA NA NA
ILE G:75 G:75 1.0 0.006 H -74.0 -43.5 NA NA NA
ILE H:75 H:75 0.0 0.0 H -59.0 -48.3 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 ILE A:75 A:75 0.0 0.0 H -64.9 -36.9 0.0 0.0 0.0 HOH
 7.138
 O
 O
ILE B:75 B:75 1.0 0.006 H -53.0 -43.8 1.0 0.006 0.0 HOH
 6.435
 N
 O
ILE C:75 C:75 0.0 0.0 H -70.9 -42.3 NA NA NA
ILE D:75 D:75 0.0 0.0 H -66.0 -53.4 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 ILE A:75 A:75 1.0 0.006 H -65.4 -41.2 1.0 0.006 0.0 HOH
 5.765
 N
 O
ILE B:75 B:75 1.0 0.006 H -63.2 -45.2 1.0 0.006 0.0 HOH
 5.711
 N
 O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 ILE A:75 A:75 0.0 0.0 H -62.8 -47.3 0.0 0.0 0.0 HOH
 5.697
 N
 O
ILE B:75 B:75 0.0 0.0 H -59.0 -42.2 0.0 0.0 0.0 HOH
 5.657
 N
 O
ILE C:75 C:75 1.0 0.006 H -63.9 -46.5 NA NA NA
ILE D:75 D:75 0.0 0.0 H -58.4 -44.0 NA NA NA
ILE E:75 E:75 0.0 0.0 H -64.4 -40.5 NA NA NA
ILE F:75 F:75 0.0 0.0 H -62.3 -44.3 NA NA NA
ILE G:75 G:75 0.0 0.0 H -55.1 -46.3 NA NA NA
ILE H:75 H:75 0.0 0.0 H -65.5 -44.7 NA NA NA
ILE I:75 I:75 0.0 0.0 H -65.0 -41.9 NA NA NA
ILE J:75 J:75 0.0 0.0 H -62.9 -41.9 NA NA NA
ILE K:75 K:75 1.0 0.006 H -59.1 -40.0 NA NA NA
ILE L:75 L:75 0.0 0.0 H -66.0 -39.3 NA NA NA
ILE M:75 M:75 1.0 0.006 H -59.8 -42.2 NA NA NA
ILE N:75 N:75 0.0 0.0 H -61.6 -48.1 NA NA NA
ILE O:75 O:75 1.0 0.006 H -60.3 -47.3 NA NA NA
ILE P:75 P:75 0.0 0.0 H -64.8 -46.1 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 VAL A:75 A:75 1.0 0.006 H -62.8 -52.0 1.0 0.006 0.0 HOH
 5.847
 N
 O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 VAL A:75 B:75 2.0 0.013 H -57.6 -48.1 2.0 0.013 0.0 HOH
 5.640
 CG2
 O
VAL B:75 A:75 1.0 0.006 H -59.2 -46.8 1.0 0.006 0.0 HOH
 5.573
 CG2
 O
VAL C:75 D:75 2.0 0.013 H -59.2 -48.1 NA NA NA
VAL D:75 C:75 0.0 0.0 H -58.8 -47.1 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ILE A:75 A:75 1.0 0.006 H -57.6 -46.9 1.0 0.006 0.0 HOH
 5.816
 N
 O
ILE B:75 B:75 1.0 0.006 H -53.1 -40.8 1.0 0.006 0.0 HOH
 5.718
 N
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ILE A:75 A:75 1.0 0.006 H -60.1 -43.2 1.0 0.006 0.0 HOH
 5.779
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 ILE A:75 A:75 1.0 0.006 H -59.5 -47.4
af-p09210-f1 1 P09210 95.05 1e-154 ILE A:75 A:75 0.0 0.0 H -60.0 -48.0
af-q16772-f1 1 Q16772 90.54 2e-146 ILE A:75 A:75 0.0 0.0 H -60.9 -47.0
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 ILE A:75 A:75 0.0 0.0 H -61.6 -47.7