Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52661040 . A C CCDS4945.1:NM_145740.3:c.212aTt>aGt_NP_665683.1:p.71I>S Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:71 A:71 0.0 0.0 H -61.6 -50.7 0.0 0.0 0.0 GSH
HED
HOH
 5.980
8.187
4.995
 CD1
N
N
 O12
O1
O
ILE B:71 B:71 1.0 0.006 H -59.2 -50.8 1.0 0.006 0.0 GSH
HED
HOH
 5.934
8.401
5.018
 CD1
N
N
 O12
O6
O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:71 A:71 1.0 0.006 H -67.9 -47.7 1.0 0.006 0.0 HED
HOH
 8.128
5.133
 N
N
 O1
O
ILE B:71 B:71 0.0 0.0 H -60.2 -51.5 0.0 0.0 0.0 HED
HOH
 8.830
5.064
 C
N
 C6
O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ILE A:71 A:71 1.0 0.006 H -62.0 -51.5 1.0 0.006 0.0 CL
ABY
HOH
 6.054
9.030
5.008
 CD1
CD1
N
 CL
CG1
O
ILE B:71 B:71 1.0 0.006 H -66.3 -49.9 1.0 0.006 0.0 CL
ABY
HOH
 6.036
8.978
5.027
 CD1
CD1
N
 CL
CA1
O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 ILE A:71 A:71 1.0 0.006 H -57.6 -53.8 1.0 0.006 0.0 P9H
HOH
 6.089
5.290
 CD1
N
 O1
O
ILE B:71 B:71 2.0 0.011 H -57.4 -54.7 2.0 0.011 0.0 P9H
HOH
 5.601
5.249
 CD1
N
 O1
O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 VAL A:71 A:71 1.0 0.006 H -64.9 -54.5 1.0 0.006 0.0 GTX
HOH
 7.074
6.373
 CG2
CG1
 O11
O
VAL B:71 B:71 2.0 0.013 H -67.0 -55.7 2.0 0.013 0.0 GTX
HOH
 6.961
6.079
 CG2
CG1
 O11
O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 ILE A:71 A:71 0.0 0.0 H -68.1 -51.6 0.0 0.0 0.0 HOH
 5.018
 N
 O
ILE B:71 B:71 1.0 0.006 H -58.1 -51.7 1.0 0.006 0.0 HOH
 5.502
 CD1
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 ILE A:71 A:71 0.0 0.0 H -58.9 -51.8 0.0 0.0 0.0 HOH
 5.087
 N
 O
ILE B:71 B:71 1.0 0.006 H -61.4 -54.3 1.0 0.006 0.0 HOH
 4.884
 N
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ILE A:70 A:71 1.0 0.006 H -59.2 -54.7 1.0 0.006 0.0 HOH
 5.128
 N
 O
ILE B:70 B:71 1.0 0.006 H -59.3 -54.7 1.0 0.006 0.0 HOH
 4.975
 N
 O
ILE C:70 C:71 1.0 0.006 H -59.2 -54.7 NA NA NA
ILE D:70 D:71 0.0 0.0 H -59.3 -54.7 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ILE A:70 A:71 1.0 0.006 H -64.1 -57.1 1.0 0.006 0.0 EAA
HOH
 9.914
5.182
 CD1
N
 OXT
O
ILE B:70 B:71 0.0 0.0 H -64.1 -57.1 0.0 0.0 0.0 EAA
HOH
 9.914
5.035
 CD1
N
 OXT
O
ILE C:70 C:71 0.0 0.0 H -64.1 -57.2 NA NA NA
ILE D:70 D:71 0.0 0.0 H -64.1 -57.2 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 ILE A:70 A:71 0.0 0.0 H -61.8 -55.0 0.0 0.0 0.0 GSB
 5.982
 CD1
 O11
ILE B:70 B:71 0.0 0.0 H -61.8 -55.0 0.0 0.0 0.0 GSB
 5.982
 CD1
 O11
ILE C:70 C:71 1.0 0.006 H -61.8 -55.0 NA NA NA
ILE D:70 D:71 0.0 0.0 H -61.7 -55.0 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 ILE A:70 A:71 1.0 0.006 H -56.3 -52.0 1.0 0.006 0.0 GTX
HOH
 5.878
4.986
 CD1
N
 O11
O
ILE B:70 B:71 1.0 0.006 H -58.5 -51.3 1.0 0.006 0.0 GTX
HOH
 5.946
4.967
 CD1
N
 O11
O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ILE A:70 A:71 3.0 0.017 H -58.8 -55.1 3.0 0.017 0.0 HOH
 5.128
 N
 O
ILE B:70 B:71 3.0 0.017 H -61.1 -53.1 3.0 0.017 0.0 HOH
 4.935
 N
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ILE A:70 A:71 1.0 0.006 H -58.3 -51.4 1.0 0.006 0.0 GTX
GOL
HOH
 5.965
8.475
4.970
 CD1
N
N
 O12
O3
O
ILE B:70 B:71 2.0 0.011 H -60.9 -52.7 2.0 0.011 0.0 GTX
HOH
 5.984
4.978
 CD1
N
 O11
O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:70 A:71 1.0 0.006 H -55.3 -52.0 1.0 0.006 0.0 GSH
MPD
HOH
 6.051
9.339
5.323
 CD1
CG1
CD1
 O11
HM1
O
ILE B:70 B:71 1.0 0.006 H -61.2 -52.6 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:70 A:71 0.0 0.0 H -59.3 -49.2 0.0 0.0 0.0 MPD
HOH
 9.310
5.305
 CG1
CD1
 H13
O
ILE B:70 B:71 0.0 0.0 H -61.3 -53.2 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:70 A:71 1.0 0.006 H -59.8 -51.9 1.0 0.006 0.0 MPD
HOH
 8.746
5.376
 CG1
CD1
 HM3
O
ILE B:70 B:71 1.0 0.006 H -56.5 -52.2 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ILE A:70 A:71 2.0 0.011 H -56.7 -52.2 2.0 0.011 0.0 BWS
GSN
EDO
EDO
EDO
HOH
 5.977
5.977
8.696
8.147
8.884
5.407
 CD1
CD1
CG1
C
CD1
CD1
 O
O
H12
H22
HO1
O
ILE B:70 B:71 2.0 0.011 H -59.1 -50.9 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 ILE A:71 A:71 6.0 0.034 H -69.1 -52.3 6.0 0.034 0.0 HOH
 5.139
 N
 O
ILE B:71 B:71 6.0 0.034 H -56.2 -56.0 6.0 0.034 0.0 HOH
 5.122
 N
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 ILE A:71 A:71 0.0 0.0 H -55.1 -58.6 0.0 0.0 0.0 GTX
HOH
 5.893
5.099
 CD1
N
 O11
O
ILE B:71 B:71 0.0 0.0 H -60.3 -53.2 0.0 0.0 0.0 GTX
HOH
 5.998
5.028
 CD1
N
 O11
O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 ILE A:71 A:71 1.0 0.006 H -59.0 -48.6 1.0 0.006 0.0 CL
ABY
HOH
 5.937
8.914
5.005
 CD1
CD1
N
 CL
CA1
O
ILE B:71 B:71 1.0 0.006 H -62.3 -50.2 1.0 0.006 0.0 CL
ABY
HOH
 5.963
8.976
5.024
 CD1
CD1
N
 CL
CA1
O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 ILE A:71 A:71 1.0 0.006 H -56.5 -51.3 1.0 0.006 0.0 GTX
HOH
 5.788
4.881
 CD1
N
 O11
O
ILE B:71 B:71 2.0 0.011 H -57.9 -53.3 2.0 0.011 0.0 GTX
HOH
 5.939
5.411
 CD1
CD1
 O11
O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 ILE A:70 A:71 1.0 0.006 H -63.5 -50.5 1.0 0.006 0.0 GSH
BME
BME
HOH
 6.201
9.785
8.239
5.092
 CD1
C
C
N
 O11
C1
C1
O
ILE B:70 B:71 2.0 0.011 H -63.7 -49.2 2.0 0.011 0.0 GSH
BME
BME
HOH
 6.259
9.715
8.395
5.019
 CD1
C
N
N
 O12
O1
C1
O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 ILE A:70 A:71 2.0 0.011 H -61.2 -50.2 2.0 0.011 0.0 HOH
 5.078
 N
 O
ILE B:70 B:71 1.0 0.006 H -62.8 -48.6 1.0 0.006 0.0 HOH
 5.154
 N
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 ALA A:70 A:71 2.0 0.017 H -75.8 -34.6 2.0 0.017 0.0 GTX
HOH
 8.341
3.512
 N
CB
 O11
O
ALA B:70 B:71 2.0 0.017 H -68.4 -37.1 2.0 0.017 0.0 GTX
HOH
 8.301
3.310
 N
CB
 O11
O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 ILE A:74 A:71 0.0 0.0 H -62.2 -50.6 0.0 0.0 0.0 GSH
CL
HOH
 5.912
7.916
4.961
 CD1
C
N
 O11
CL
O
ILE B:74 B:71 1.0 0.006 H -58.1 -52.7 1.0 0.006 0.0 GSH
CL
HOH
 5.993
7.980
4.977
 CD1
C
N
 O11
CL
O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 ILE A:71 A:71 1.0 0.006 H -54.1 -53.2 1.0 0.006 0.0 GTX
HOH
 6.172
4.998
 CD1
N
 O11
O
ILE B:71 B:71 3.0 0.017 H -67.2 -46.6 3.0 0.017 0.0 GTX
HOH
 5.823
5.198
 CD1
N
 O11
O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 ILE A:70 A:71 1.0 0.006 H -55.8 -50.6 1.0 0.006 0.0 HOH
 5.088
 N
 O
ILE B:70 B:71 1.0 0.006 H -63.7 -52.0 1.0 0.006 0.0 HOH
 5.098
 N
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 ILE A:70 A:71 0.0 0.0 H -58.4 -59.3 0.0 0.0 0.0 GVX
EDO
EDO
HOH
 5.992
9.638
8.596
4.981
 CD1
CD1
C
N
 O03
O2
C1
O
ILE B:70 B:71 1.0 0.006 H -60.5 -54.6 1.0 0.006 0.0 GVX
HOH
 6.096
4.832
 CD1
N
 O03
O
ILE C:70 C:71 1.0 0.006 H -58.2 -52.0 NA NA NA
ILE D:70 D:71 1.0 0.006 H -56.5 -51.9 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 ILE A:68 A:71 2.0 0.011 H -59.6 -54.7 2.0 0.011 0.0 LZ6
HOH
 6.312
4.868
 CD1
N
 O37
O
ILE B:68 B:71 2.0 0.011 H -66.0 -54.3 2.0 0.011 0.0 LZ6
HOH
 6.432
4.965
 CD1
N
 O37
O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 ILE A:71 A:71 1.0 0.006 H -60.0 -50.3 1.0 0.006 0.0 HOH
 5.145
 N
 O
ILE B:71 B:71 1.0 0.006 H -68.6 -50.0 1.0 0.006 0.0 HOH
 4.718
 N
 O
ILE C:71 C:71 1.0 0.006 H -60.7 -53.7 NA NA NA
ILE D:71 D:71 1.0 0.006 H -67.8 -49.6 NA NA NA
ILE E:71 E:71 0.0 0.0 H -60.6 -43.2 NA NA NA
ILE F:71 F:71 1.0 0.006 H -63.8 -48.1 NA NA NA
ILE G:71 G:71 1.0 0.006 H -55.4 -52.9 NA NA NA
ILE H:71 H:71 0.0 0.0 H -62.0 -48.2 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 ILE A:71 A:71 1.0 0.006 H -50.5 -58.4 1.0 0.006 0.0 GSH
HOH
 5.893
5.280
 CD1
CD1
 O12
O
ILE B:71 B:71 0.0 0.0 H -75.2 -52.1 0.0 0.0 0.0 GSH
HOH
 6.441
4.924
 CD1
N
 O12
O
ILE C:71 C:71 0.0 0.0 H -55.1 -57.0 NA NA NA
ILE D:71 D:71 1.0 0.006 H -62.4 -49.9 NA NA NA
ILE E:71 E:71 1.0 0.006 H -65.3 -55.4 NA NA NA
ILE F:71 F:71 1.0 0.006 H -49.6 -54.7 NA NA NA
ILE G:71 G:71 1.0 0.006 H -52.9 -46.2 NA NA NA
ILE H:71 H:71 1.0 0.006 H -62.9 -44.5 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ILE A:71 A:71 1.0 0.006 H -52.9 -59.1 1.0 0.006 0.0 HOH
 5.107
 N
 O
ILE B:71 B:71 0.0 0.0 H -61.9 -49.7 0.0 0.0 0.0 GSH
HOH
 6.052
5.375
 CD1
N
 O11
O
ILE C:71 C:71 2.0 0.011 H -56.7 -63.5 NA NA NA
ILE D:71 D:71 0.0 0.0 H -53.1 -48.9 NA NA NA
ILE E:71 E:71 3.0 0.017 H -60.0 -46.1 NA NA NA
ILE F:71 F:71 2.0 0.011 H -49.8 -55.4 NA NA NA
ILE G:71 G:71 2.0 0.011 H -50.7 -55.2 NA NA NA
ILE H:71 H:71 1.0 0.006 H -63.8 -49.7 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ILE A:71 A:71 1.0 0.006 H -66.5 -49.8 1.0 0.006 0.0 GSH
HOH
 5.983
5.059
 CD1
N
 O12
O
ILE B:71 B:71 1.0 0.006 H -48.7 -53.5 1.0 0.006 0.0 GSH
HOH
 5.874
5.064
 CD1
N
 O11
O
ILE C:71 C:71 1.0 0.006 H -61.9 -54.6 NA NA NA
ILE D:71 D:71 0.0 0.0 H -55.2 -55.6 NA NA NA
ILE E:71 E:71 1.0 0.006 H -59.8 -54.1 NA NA NA
ILE F:71 F:71 1.0 0.006 H -54.0 -54.8 NA NA NA
ILE G:71 G:71 2.0 0.011 H -53.4 -54.1 NA NA NA
ILE H:71 H:71 1.0 0.006 H -54.6 -55.2 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 ILE A:71 A:71 2.0 0.011 H -56.3 -58.6 2.0 0.011 0.0 BOB
HOH
 6.062
5.326
 CD1
CD1
 O12
O
ILE B:71 B:71 0.0 0.0 H -58.1 -52.0 0.0 0.0 0.0 BOB
HOH
 6.000
5.861
 CD1
CG2
 O12
O
ILE C:71 C:71 1.0 0.006 H -72.6 -47.8 NA NA NA
ILE D:71 D:71 1.0 0.006 H -53.7 -52.1 NA NA NA
ILE E:71 E:71 1.0 0.006 H -71.5 -49.0 NA NA NA
ILE F:71 F:71 1.0 0.006 H -50.1 -58.1 NA NA NA
ILE G:71 G:71 1.0 0.006 H -51.4 -59.4 NA NA NA
ILE H:71 H:71 0.0 0.0 H -65.3 -55.2 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 ILE A:71 A:71 0.0 0.0 H -66.5 -47.3 0.0 0.0 0.0 GSH
HOH
 6.692
5.797
 CD1
CD1
 O12
O
ILE B:71 B:71 1.0 0.006 H -63.5 -56.8 1.0 0.006 0.0 GSH
HOH
 6.036
5.497
 CD1
CD1
 O12
O
ILE C:71 C:71 0.0 0.0 H -65.1 -47.6 NA NA NA
ILE D:71 D:71 0.0 0.0 H -47.7 -53.3 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 ILE A:71 A:71 0.0 0.0 H -61.6 -49.6 0.0 0.0 0.0 GSH
HOH
 6.161
5.202
 CD1
N
 O11
O
ILE B:71 B:71 1.0 0.006 H -64.8 -48.5 1.0 0.006 0.0 GSH
HOH
 6.070
4.901
 CD1
N
 O11
O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 ILE A:71 A:71 0.0 0.0 H -71.4 -45.3 0.0 0.0 0.0 GSH
HOH
 6.293
4.925
 CD1
N
 O12
O
ILE B:71 B:71 0.0 0.0 H -68.1 -41.4 0.0 0.0 0.0 GSH
HOH
 6.384
4.960
 CD1
N
 O12
O
ILE C:71 C:71 0.0 0.0 H -69.9 -43.2 NA NA NA
ILE D:71 D:71 0.0 0.0 H -74.0 -44.3 NA NA NA
ILE E:71 E:71 0.0 0.0 H -69.5 -45.1 NA NA NA
ILE F:71 F:71 0.0 0.0 H -67.2 -49.4 NA NA NA
ILE G:71 G:71 1.0 0.006 H -67.3 -44.8 NA NA NA
ILE H:71 H:71 0.0 0.0 H -68.5 -45.4 NA NA NA
ILE I:71 I:71 1.0 0.006 H -62.2 -44.1 NA NA NA
ILE J:71 J:71 0.0 0.0 H -68.7 -46.3 NA NA NA
ILE K:71 K:71 1.0 0.006 H -66.8 -45.3 NA NA NA
ILE L:71 L:71 0.0 0.0 H -68.5 -47.5 NA NA NA
ILE M:71 M:71 0.0 0.0 H -62.6 -51.3 NA NA NA
ILE N:71 N:71 1.0 0.006 H -66.8 -48.3 NA NA NA
ILE O:71 O:71 1.0 0.006 H -64.7 -45.7 NA NA NA
ILE P:71 P:71 0.0 0.0 H -61.5 -46.8 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 ILE A:71 A:71 1.0 0.006 H -61.1 -50.4 1.0 0.006 0.0 GSH
EDO
HOH
 6.159
9.367
5.032
 CD1
C
N
 O11
C1
O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 ILE A:71 B:71 0.0 0.0 H -60.7 -49.0 0.0 0.0 0.0 GSH
HOH
 6.208
4.997
 CD1
N
 O11
O
ILE B:71 A:71 1.0 0.006 H -62.2 -48.4 1.0 0.006 0.0 GSH
HOH
 6.343
4.905
 CD1
N
 O12
O
ILE C:71 D:71 0.0 0.0 H -63.9 -47.6 NA NA NA
ILE D:71 C:71 0.0 0.0 H -61.8 -48.8 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ILE A:71 A:71 0.0 0.0 H -58.0 -52.5 0.0 0.0 0.0 GSH
HOH
 6.101
4.954
 CD1
N
 O11
O
ILE B:71 B:71 1.0 0.006 H -62.3 -52.9 1.0 0.006 0.0 HOH
 5.224
 N
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ILE A:71 A:71 1.0 0.006 H -59.4 -50.4 1.0 0.006 0.0 CL
CL
HOH
 8.451
8.148
4.992
 N
N
N
 CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 ILE A:71 A:71 0.0 0.0 H -56.9 -51.6
af-p09210-f1 1 P09210 95.05 1e-154 ILE A:71 A:71 0.0 0.0 H -58.7 -50.2
af-q16772-f1 1 Q16772 90.54 2e-146 ILE A:71 A:71 0.0 0.0 H -60.4 -48.6
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 ILE A:71 A:71 1.0 0.006 H -62.0 -50.0