Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52661061 . T A CCDS4945.1:NM_145740.3:c.191aAg>aTg_NP_665683.1:p.64K>M Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 LYS A:64 A:64 72.0 0.36 E -103.5 83.1 63.0 0.315 0.045 B:P08263:0.045
 HOH
 2.658
 O
 O
LYS B:64 B:64 99.0 0.495 E -104.7 86.8 88.0 0.44 0.055 A:P08263:0.055
 HOH
 2.731
 NZ
 O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 LYS A:64 A:64 80.0 0.4 E -106.5 89.4 69.0 0.345 0.055 B:P08263:0.055
 HOH
 2.495
 NZ
 O
LYS B:64 B:64 95.0 0.475 E -111.7 84.2 86.0 0.43 0.045 A:P08263:0.045
 HOH
 2.671
 O
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 LYS A:64 A:64 80.0 0.4 E -108.1 85.3 69.0 0.345 0.055 B:P08263:0.055
 HOH
 2.678
 O
 O
LYS B:64 B:64 100.0 0.5 E -115.9 88.6 90.0 0.45 0.05 A:P08263:0.05
 HOH
 2.804
 O
 O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 LYS A:64 A:64 95.0 0.475 E -116.4 87.2 85.0 0.425 0.05 B:P08263:0.05
 HOH
 3.157
 O
 O
LYS B:64 B:64 88.0 0.44 E -112.6 80.8 77.0 0.385 0.055 A:P08263:0.055
 HOH
 2.898
 O
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 LYS A:64 A:64 96.0 0.48 E -105.6 79.9 85.0 0.425 0.055 B:P08263:0.055
 HOH
 5.023
 N
 O
LYS B:64 B:64 95.0 0.475 E -108.7 68.4 89.0 0.445 0.03 A:P08263:0.03
 HOH
 7.323
 O
 O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 LYS A:64 A:64 95.0 0.475 E -118.5 85.9 85.0 0.425 0.05 B:P08263:0.05
 HOH
 2.803
 O
 O
LYS B:64 B:64 91.0 0.455 E -115.7 84.5 81.0 0.405 0.05 A:P08263:0.05
 HOH
 2.804
 O
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 LYS A:64 A:64 91.0 0.455 E -118.2 88.6 79.0 0.395 0.06 B:P08263:0.06
 HOH
 2.566
 O
 O
LYS B:64 B:64 89.0 0.445 E -108.4 91.9 81.0 0.405 0.04 A:P08263:0.04
 HOH
 2.946
 O
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 LYS A:63 A:64 83.0 0.415 E -114.2 88.3 74.0 0.37 0.045 B:P08263:0.045
 HOH
 2.625
 O
 O
LYS B:63 B:64 82.0 0.41 E -114.2 88.2 73.0 0.365 0.045 A:P08263:0.045
 HOH
 2.625
 O
 O
LYS C:63 C:64 84.0 0.42 E -114.2 88.2 NA NA NA
LYS D:63 D:64 82.0 0.41 E -114.2 88.2 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 LYS A:63 A:64 86.0 0.43 E -112.6 85.1 77.0 0.385 0.045 B:P08263:0.045
 HOH
 2.718
 O
 O
LYS B:63 B:64 86.0 0.43 E -112.6 85.0 78.0 0.39 0.04 A:P08263:0.04
 HOH
 2.718
 O
 O
LYS C:63 C:64 85.0 0.425 E -112.6 85.1 NA NA NA
LYS D:63 D:64 86.0 0.43 E -112.6 85.1 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 LYS A:63 A:64 96.0 0.48 E -100.4 83.9 85.0 0.425 0.055 B:P08263:0.055
LYS B:63 B:64 93.0 0.465 E -100.4 83.9 82.0 0.41 0.055 A:P08263:0.055
LYS C:63 C:64 92.0 0.46 E -100.5 83.8 NA NA NA
LYS D:63 D:64 92.0 0.46 E -100.4 83.9 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 LYS A:63 A:64 88.0 0.44 E -102.8 80.1 78.0 0.39 0.05 B:P08263:0.05
 HOH
 3.008
 O
 O
LYS B:63 B:64 103.0 0.515 E -103.7 101.5 92.0 0.46 0.055 A:P08263:0.055
 HOH
 2.798
 CE
 O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 LYS A:63 A:64 101.0 0.505 E -111.6 105.4 90.0 0.45 0.055 B:P08263:0.055
 HOH
 2.817
 O
 O
LYS B:63 B:64 112.0 0.56 E -120.4 93.0 102.0 0.51 0.05 A:P08263:0.05
 HOH
 3.290
 O
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 LYS A:63 A:64 89.0 0.445 E -101.9 125.0 78.0 0.39 0.055 B:P08263:0.055
 HOH
 2.648
 NZ
 O
LYS B:63 B:64 93.0 0.465 E -119.5 111.7 83.0 0.415 0.05 A:P08263:0.05
 HOH
 2.599
 O
 O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 LYS A:63 A:64 89.0 0.445 E -107.3 87.5 89.0 0.445 0.0 MPD
MPD
HOH
 2.803
4.115
2.831
 O
NZ
O
 HM1
HM2
O
LYS B:63 B:64 89.0 0.445 E -107.4 93.4 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 LYS A:63 A:64 87.0 0.435 E -107.0 86.5 87.0 0.435 0.0 MPD
MPD
HOH
 2.191
4.284
2.781
 N
NZ
O
 HM2
HM3
O
LYS B:63 B:64 94.0 0.47 E -112.9 87.5 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 LYS A:63 A:64 84.0 0.42 E -113.8 88.4 84.0 0.42 0.0 MPD
MPD
HOH
 2.534
4.007
2.782
 N
NZ
O
 HM3
HM2
O
LYS B:63 B:64 96.0 0.48 E -115.1 93.0 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 LYS A:63 A:64 96.0 0.48 E -110.7 90.2 96.0 0.48 0.0 EDO
EDO
HOH
 5.986
2.411
2.782
 O
O
NZ
 HO2
H12
O
LYS B:63 B:64 97.0 0.485 E -110.9 89.8 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 LYS A:64 A:64 78.0 0.39 E -107.0 90.6 69.0 0.345 0.045 B:P08263:0.045
 HOH
 2.630
 NZ
 O
LYS B:64 B:64 91.0 0.455 E -128.0 89.8 80.0 0.4 0.055 A:P08263:0.055
 HOH
 2.411
 NZ
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 LYS A:64 A:64 93.0 0.465 E -107.5 82.4 82.0 0.41 0.055 B:P08263:0.055
 HOH
 2.896
 O
 O
LYS B:64 B:64 101.0 0.505 E -114.4 86.6 89.0 0.445 0.06 A:P08263:0.06
 HOH
 2.818
 O
 O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 LYS A:64 A:64 79.0 0.395 E -107.2 84.1 68.0 0.34 0.055 B:P08263:0.055
 HOH
 2.642
 O
 O
LYS B:64 B:64 97.0 0.485 E -115.4 88.3 88.0 0.44 0.045 A:P08263:0.045
 HOH
 2.824
 O
 O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 LYS A:64 A:64 91.0 0.455 E -98.2 127.5 81.0 0.405 0.05 B:P08263:0.05
 HOH
 2.722
 NZ
 O
LYS B:64 B:64 102.0 0.51 E -111.6 106.1 91.0 0.455 0.055 A:P08263:0.055
 HOH
 2.620
 N
 O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 LYS A:63 A:64 97.0 0.485 E -112.1 80.3 88.0 0.44 0.045 B:P08263:0.045
 HOH
 2.845
 NZ
 O
LYS B:63 B:64 99.0 0.495 E -109.2 79.0 90.0 0.45 0.045 A:P08263:0.045
 HOH
 3.003
 N
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 LYS A:63 A:64 95.0 0.475 E -117.4 86.0 88.0 0.44 0.035 B:P08263:0.035
 HOH
 2.575
 NZ
 O
LYS B:63 B:64 90.0 0.45 E -114.7 82.8 79.0 0.395 0.055 A:P08263:0.055
 HOH
 2.688
 O
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 LYS A:63 A:64 93.0 0.465 E -110.5 86.3 81.0 0.405 0.06 B:P08263:0.06
 HOH
 2.339
 NZ
 O
LYS B:63 B:64 101.0 0.505 E -110.2 87.8 90.0 0.45 0.055 A:P08263:0.055
 HOH
 2.603
 NZ
 O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 LYS A:67 A:64 89.0 0.445 E -108.4 88.6 79.0 0.395 0.05 B:P08263:0.05
 HOH
 2.642
 NZ
 O
LYS B:67 B:64 96.0 0.48 E -120.8 92.5 87.0 0.435 0.045 A:P08263:0.045
 HOH
 2.955
 O
 O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 LYS A:64 A:64 95.0 0.475 E -111.6 83.6 84.0 0.42 0.055 B:P08263:0.055
 HOH
 2.525
 NZ
 O
LYS B:64 B:64 110.0 0.55 E -108.6 86.3 101.0 0.505 0.045 A:P08263:0.045
 HOH
 2.769
 O
 O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 LYS A:63 A:64 79.0 0.395 E -111.0 86.9 69.0 0.345 0.05 B:P08263:0.05
 HOH
 2.660
 O
 O
LYS B:63 B:64 97.0 0.485 E -109.2 85.6 88.0 0.44 0.045 A:P08263:0.045
 HOH
 2.747
 O
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 LYS A:63 A:64 87.0 0.435 E -103.8 96.9 77.0 0.385 0.05 B:P08263:0.05
 HOH
 2.963
 O
 O
LYS B:63 B:64 91.0 0.455 E -111.0 83.0 83.0 0.415 0.04 A:P08263:0.04
 HOH
 2.819
 O
 O
LYS C:63 C:64 91.0 0.455 E -113.1 88.4 NA NA NA
LYS D:63 D:64 91.0 0.455 E -104.6 84.1 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 LYS A:61 A:64 91.0 0.455 E -101.3 97.3 79.0 0.395 0.06 B:P08263:0.06
 HOH
 3.232
 O
 O
LYS B:61 B:64 90.0 0.45 E -113.3 99.2 80.0 0.4 0.05 A:P08263:0.05
 HOH
 2.626
 O
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 LYS A:64 A:64 93.0 0.465 E -106.1 86.2 84.0 0.42 0.045 B:P09210:0.045
 HOH
 2.631
 CG
 O
LYS B:64 B:64 91.0 0.455 E -97.7 105.8 82.0 0.41 0.045 A:P09210:0.045
 HOH
 2.982
 NZ
 O
LYS C:64 C:64 91.0 0.455 E -107.7 83.4 NA NA NA
LYS D:64 D:64 93.0 0.465 E -104.7 115.3 NA NA NA
LYS E:64 E:64 98.0 0.49 E -102.9 68.3 NA NA NA
LYS F:64 F:64 91.0 0.455 E -103.8 78.2 NA NA NA
LYS G:64 G:64 92.0 0.46 E -108.4 82.6 NA NA NA
LYS H:64 H:64 93.0 0.465 E -108.3 78.1 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 LYS A:64 A:64 89.0 0.445 E -110.6 77.1 80.0 0.4 0.045 B:P09210:0.045
 HOH
 2.916
 O
 O
LYS B:64 B:64 96.0 0.48 E -97.3 91.0 86.0 0.43 0.05 A:P09210:0.05
 HOH
 3.042
 O
 O
LYS C:64 C:64 76.0 0.38 E -92.1 74.6 NA NA NA
LYS D:64 D:64 96.0 0.48 E -101.1 76.3 NA NA NA
LYS E:64 E:64 84.0 0.42 E -100.0 64.7 NA NA NA
LYS F:64 F:64 92.0 0.46 E -97.3 77.6 NA NA NA
LYS G:64 G:64 91.0 0.455 -125.4 76.9 NA NA NA
LYS H:64 H:64 89.0 0.445 E -106.3 73.0 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 LYS A:64 A:64 100.0 0.5 E -112.3 90.4 89.0 0.445 0.055 B:P08263:0.055
 HOH
 5.736
 O
 O
LYS B:64 B:64 80.0 0.4 E -115.7 104.9 68.0 0.34 0.06 A:P08263:0.06
 HOH
 6.268
 O
 O
LYS C:64 C:64 92.0 0.46 E -101.5 87.2 NA NA NA
LYS D:64 D:64 87.0 0.435 E -112.9 96.7 NA NA NA
LYS E:64 E:64 80.0 0.4 E -128.3 72.9 NA NA NA
LYS F:64 F:64 85.0 0.425 E -127.4 80.3 NA NA NA
LYS G:64 G:64 88.0 0.44 E -116.6 95.9 NA NA NA
LYS H:64 H:64 93.0 0.465 E -124.2 64.2 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 LYS A:64 A:64 98.0 0.49 E -103.7 89.8 88.0 0.44 0.05 B:P08263:0.05
 HOH
 5.482
 O
 O
LYS B:64 B:64 85.0 0.425 E -117.2 103.2 73.0 0.365 0.06 A:P08263:0.06
 HOH
 3.614
 O
 O
LYS C:64 C:64 89.0 0.445 E -104.4 85.3 NA NA NA
LYS D:64 D:64 95.0 0.475 E -116.6 107.4 NA NA NA
LYS E:64 E:64 97.0 0.485 E -108.9 92.4 NA NA NA
LYS F:64 F:64 91.0 0.455 E -114.4 93.1 NA NA NA
LYS G:64 G:64 93.0 0.465 E -102.4 87.4 NA NA NA
LYS H:64 H:64 94.0 0.47 E -114.1 89.3 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 LYS A:64 A:64 103.0 0.515 E -103.1 100.2 92.0 0.46 0.055 B:P08263:0.055
 HOH
 7.761
 O
 O
LYS B:64 B:64 79.0 0.395 E -119.9 96.7 68.0 0.34 0.055 A:P08263:0.055
 HOH
 7.948
 O
 O
LYS C:64 C:64 95.0 0.475 E -117.1 84.0 NA NA NA
LYS D:64 D:64 83.0 0.415 E -112.9 95.6 NA NA NA
LYS E:64 E:64 100.0 0.5 E -134.5 75.1 NA NA NA
LYS F:64 F:64 102.0 0.51 E -134.8 71.4 NA NA NA
LYS G:64 G:64 84.0 0.42 E -114.0 93.0 NA NA NA
LYS H:64 H:64 80.0 0.4 E -121.6 87.3 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 LYS A:64 A:64 97.0 0.485 E -97.1 97.3 87.0 0.435 0.05 B:P09210:0.05
 HOH
 2.864
 O
 O
LYS B:64 B:64 106.0 0.53 E -102.9 88.4 98.0 0.49 0.04 A:P09210:0.04
 HOH
 2.732
 O
 O
LYS C:64 C:64 96.0 0.48 E -101.4 106.7 NA NA NA
LYS D:64 D:64 94.0 0.47 E -99.0 72.4 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 LYS A:64 A:64 107.0 0.535 E -119.2 82.5 98.0 0.49 0.045 B:Q16772:0.045
 HOH
 2.765
 O
 O
LYS B:64 B:64 111.0 0.555 E -117.6 80.4 101.0 0.505 0.05 A:Q16772:0.05
 HOH
 2.817
 O
 O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 LYS A:64 A:64 110.0 0.55 E -103.6 82.6 102.0 0.51 0.04 B:Q16772:0.04
 HOH
 2.587
 O
 O
LYS B:64 B:64 107.0 0.535 E -111.3 82.6 97.0 0.485 0.05 A:Q16772:0.05
 HOH
 2.942
 O
 O
LYS C:64 C:64 115.0 0.575 E -99.1 83.0 NA NA NA
LYS D:64 D:64 110.0 0.55 E -109.5 90.4 NA NA NA
LYS E:64 E:64 106.0 0.53 E -102.5 86.4 NA NA NA
LYS F:64 F:64 100.0 0.5 E -99.5 82.3 NA NA NA
LYS G:64 G:64 96.0 0.48 E -99.9 87.4 NA NA NA
LYS H:64 H:64 107.0 0.535 E -104.1 90.8 NA NA NA
LYS I:64 I:64 104.0 0.52 E -111.8 91.3 NA NA NA
LYS J:64 J:64 105.0 0.525 E -106.1 86.0 NA NA NA
LYS K:64 K:64 105.0 0.525 E -101.3 87.1 NA NA NA
LYS L:64 L:64 106.0 0.53 E -111.2 86.5 NA NA NA
LYS M:64 M:64 98.0 0.49 E -106.8 84.9 NA NA NA
LYS N:64 N:64 105.0 0.525 E -107.4 86.3 NA NA NA
LYS O:64 O:64 100.0 0.5 E -113.7 86.3 NA NA NA
LYS P:64 P:64 104.0 0.52 E -103.7 86.3 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 LYS A:64 A:64 117.0 0.585 E -103.6 90.2 108.0 0.54 0.045 A:M9ZT87:0.045
 HOH
 3.022
 O
 O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 LYS A:64 B:64 116.0 0.58 E -100.5 88.3 107.0 0.535 0.045 B:M9ZT87:0.045
 HOH
 7.806
 O
 O
LYS B:64 A:64 113.0 0.565 E -101.3 88.3 105.0 0.525 0.04 A:M9ZT87:0.04
 HOH
 7.786
 O
 O
LYS C:64 D:64 116.0 0.58 E -100.2 88.8 NA NA NA
LYS D:64 C:64 113.0 0.565 E -101.1 87.6 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 LYS A:64 A:64 79.0 0.395 E -117.8 99.1 67.0 0.335 0.06 B:P08263+P04903:0.06
 HOH
 3.052
 NZ
 O
LYS B:64 B:64 94.0 0.47 E -104.0 67.9 85.0 0.425 0.045 A:P08263+P04903:0.045
 HOH
 7.125
 O
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 LYS A:64 A:64 85.0 0.425 E -114.1 88.8 75.0 0.375 0.05 A:P08263+P04903:0.05
 HOH
 2.838
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 LYS A:64 A:64 92.0 0.46 E -109.6 83.1
af-p09210-f1 1 P09210 95.05 1e-154 LYS A:64 A:64 91.0 0.455 E -109.4 87.1
af-q16772-f1 1 Q16772 90.54 2e-146 LYS A:64 A:64 104.0 0.52 E -106.8 88.5
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 LYS A:64 A:64 107.0 0.535 E -105.8 88.8