Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52661070 . T A CCDS4945.1:NM_145740.3:c.182gAt>gTt_NP_665683.1:p.61D>V Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ASP A:61 A:61 51.0 0.34 T 49.5 49.3 27.0 0.18 0.16 B:P08263:0.16
 HOH
 2.760
 OD1
 O
ASP B:61 B:61 73.0 0.487 T 45.5 50.3 50.0 0.333 0.154 A:P08263:0.153
 HOH
 2.895
 N
 O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ASP A:61 A:61 69.0 0.46 T 45.1 48.9 47.0 0.313 0.147 B:P08263:0.147
 HOH
 3.598
 N
 O
ASP B:61 B:61 81.0 0.54 T 46.4 42.2 56.0 0.373 0.167 A:P08263:0.167
 HOH
 2.976
 N
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 ASP A:61 A:61 51.0 0.34 T 51.4 41.9 27.0 0.18 0.16 B:P08263:0.16
 HOH
 2.905
 OD1
 O
ASP B:61 B:61 78.0 0.52 T 50.5 41.8 53.0 0.353 0.167 A:P08263:0.167
 HOH
 2.636
 O
 O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 ASP A:61 A:61 79.0 0.527 T 53.1 42.5 53.0 0.353 0.174 B:P08263:0.173
 HOH
 2.597
 OD1
 O
ASP B:61 B:61 89.0 0.593 T 56.0 31.1 74.0 0.493 0.1 A:P08263:0.1
 HOH
 6.843
 N
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 ASP A:61 A:61 83.0 0.553 T 49.1 40.6 57.0 0.38 0.173 B:P08263:0.173
 HOH
 2.439
 OD1
 O
ASP B:61 B:61 92.0 0.613 T 51.2 44.2 67.0 0.447 0.166 A:P08263:0.167
 HOH
 3.210
 OD1
 O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 ASP A:61 A:61 67.0 0.447 T 39.8 51.6 43.0 0.287 0.16 B:P08263:0.16
 HOH
 2.738
 N
 O
ASP B:61 B:61 84.0 0.56 T 45.6 42.3 60.0 0.4 0.16 A:P08263:0.16
 HOH
 2.614
 N
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 ASP A:61 A:61 80.0 0.533 T 49.3 46.3 53.0 0.353 0.18 B:P08263:0.18
 HOH
 2.794
 OD1
 O
ASP B:61 B:61 89.0 0.593 T 53.8 40.8 68.0 0.453 0.14 A:P08263:0.14
 HOH
 3.082
 N
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ASP A:60 A:61 74.0 0.493 T 47.1 39.3 55.0 0.367 0.126 B:P08263:0.127
 HOH
 3.116
 N
 O
ASP B:60 B:61 78.0 0.52 T 47.1 39.3 58.0 0.387 0.133 A:P08263:0.133
 HOH
 3.116
 N
 O
ASP C:60 C:61 77.0 0.513 T 47.1 39.3 NA NA NA
ASP D:60 D:61 79.0 0.527 T 47.2 39.3 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 ASP A:60 A:61 84.0 0.56 T 50.5 35.1 61.0 0.407 0.153 B:P08263:0.153
 HOH
 3.125
 N
 O
ASP B:60 B:61 83.0 0.553 T 50.4 35.1 61.0 0.407 0.146 A:P08263:0.147
 HOH
 3.124
 N
 O
ASP C:60 C:61 83.0 0.553 T 50.5 35.1 NA NA NA
ASP D:60 D:61 85.0 0.567 T 50.5 35.1 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 ASP A:60 A:61 76.0 0.507 T 44.6 38.4 57.0 0.38 0.127 B:P08263:0.127
ASP B:60 B:61 76.0 0.507 T 44.6 38.4 56.0 0.373 0.134 A:P08263:0.133
ASP C:60 C:61 75.0 0.5 T 44.7 38.4 NA NA NA
ASP D:60 D:61 76.0 0.507 T 44.5 38.5 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 ASP A:60 A:61 79.0 0.527 T 45.4 44.6 60.0 0.4 0.127 B:P08263:0.127
 HOH
 3.502
 N
 O
ASP B:60 B:61 90.0 0.6 T 44.7 47.9 67.0 0.447 0.153 A:P08263:0.153
 HOH
 3.248
 N
 O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ASP A:60 A:61 83.0 0.553 T 44.0 47.8 63.0 0.42 0.133 B:P08263:0.133
 HOH
 3.086
 N
 O
ASP B:60 B:61 83.0 0.553 T 54.1 36.2 63.0 0.42 0.133 A:P08263:0.133
 HOH
 8.375
 N
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 ASP A:60 A:61 76.0 0.507 T 52.7 42.7 57.0 0.38 0.127 B:P08263:0.127
 HOH
 2.953
 N
 O
ASP B:60 B:61 78.0 0.52 T 49.7 47.0 59.0 0.393 0.127 A:P08263:0.127
 HOH
 3.134
 N
 O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ASP A:60 A:61 57.0 0.38 T 47.9 45.6 57.0 0.38 0.0 MPD
HOH
 5.815
2.774
 O
OD1
 HO4
O
ASP B:60 B:61 92.0 0.613 T 52.7 40.2 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ASP A:60 A:61 59.0 0.393 T 47.6 47.4 59.0 0.393 0.0 MPD
HOH
 5.604
2.530
 O
OD1
 H52
O
ASP B:60 B:61 82.0 0.547 T 52.0 47.7 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ASP A:60 A:61 49.0 0.327 T 51.7 51.4 49.0 0.327 0.0 MPD
HOH
 5.816
2.793
 O
N
 H53
O
ASP B:60 B:61 79.0 0.527 T 46.9 44.7 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 ASP A:60 A:61 83.0 0.553 T 50.8 43.8 83.0 0.553 0.0 EDO
EDO
HOH
 6.796
5.339
2.624
 O
OD1
OD1
 HO1
HO2
O
ASP B:60 B:61 85.0 0.567 T 53.1 39.4 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 ASP A:61 A:61 59.0 0.393 T 47.8 42.4 35.0 0.233 0.16 B:P08263:0.16
 HOH
 2.694
 O
 O
ASP B:61 B:61 89.0 0.593 T 36.6 51.4 64.0 0.427 0.166 A:P08263:0.167
 HOH
 2.782
 OD1
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 ASP A:61 A:61 74.0 0.493 T 50.3 47.9 48.0 0.32 0.173 B:P08263:0.173
 HOH
 2.756
 N
 O
ASP B:61 B:61 88.0 0.587 T 50.5 43.7 65.0 0.433 0.154 A:P08263:0.153
 HOH
 2.777
 N
 O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 ASP A:61 A:61 52.0 0.347 T 50.5 44.5 30.0 0.2 0.147 B:P08263:0.147
 HOH
 3.123
 O
 O
ASP B:61 B:61 79.0 0.527 T 51.5 40.2 54.0 0.36 0.167 A:P08263:0.167
 HOH
 2.712
 O
 O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 ASP A:61 A:61 79.0 0.527 T 49.2 45.0 61.0 0.407 0.12 B:P08263:0.12
 HOH
 2.429
 OD1
 O
ASP B:61 B:61 82.0 0.547 T 49.2 42.2 60.0 0.4 0.147 A:P08263:0.147
 HOH
 2.743
 N
 O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 ASP A:60 A:61 82.0 0.547 T 49.9 43.1 57.0 0.38 0.167 B:P08263:0.167
 HOH
 3.282
 N
 O
ASP B:60 B:61 83.0 0.553 T 49.8 38.5 60.0 0.4 0.153 A:P08263:0.153
 HOH
 3.013
 N
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 ASP A:60 A:61 78.0 0.52 T 49.8 40.0 53.0 0.353 0.167 B:P08263:0.167
 HOH
 2.753
 O
 O
ASP B:60 B:61 56.0 0.373 T 53.4 41.8 28.0 0.187 0.186 A:P08263:0.187
 HOH
 2.936
 O
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 ASP A:60 A:61 81.0 0.54 T 47.6 41.9 55.0 0.367 0.173 B:P08263:0.173
 HOH
 2.501
 OD1
 O
ASP B:60 B:61 90.0 0.6 T 54.2 47.4 69.0 0.46 0.14 A:P08263:0.14
 HOH
 2.931
 O
 O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 ASP A:64 A:61 67.0 0.447 T 40.0 50.8 43.0 0.287 0.16 B:P08263:0.16
 HOH
 5.290
 C
 O
ASP B:64 B:61 83.0 0.553 T 48.1 48.8 65.0 0.433 0.12 A:P08263:0.12
 HOH
 3.353
 OD1
 O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 ASP A:61 A:61 85.0 0.567 T 56.3 46.9 61.0 0.407 0.16 B:P08263:0.16
 HOH
 3.126
 N
 O
ASP B:61 B:61 91.0 0.607 T 55.0 40.9 69.0 0.46 0.147 A:P08263:0.147
 HOH
 4.387
 OD2
 O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 ASP A:60 A:61 52.0 0.347 T 47.8 46.9 28.0 0.187 0.16 B:P08263:0.16
 HOH
 2.682
 OD1
 O
ASP B:60 B:61 84.0 0.56 T 46.4 43.8 60.0 0.4 0.16 A:P08263:0.16
 HOH
 2.886
 N
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 ASP A:60 A:61 81.0 0.54 T 47.9 45.6 57.0 0.38 0.16 B:P08263:0.16
 HOH
 2.553
 O
 O
ASP B:60 B:61 83.0 0.553 T 53.1 52.0 62.0 0.413 0.14 A:P08263:0.14
 HOH
 2.271
 OD1
 O
ASP C:60 C:61 78.0 0.52 T 48.1 48.7 NA NA NA
ASP D:60 D:61 83.0 0.553 T 52.8 42.6 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 ASP A:58 A:61 86.0 0.573 T 42.2 47.1 67.0 0.447 0.126 B:P08263:0.127
 HOH
 3.570
 N
 O
ASP B:58 B:61 86.0 0.573 T 50.3 42.1 66.0 0.44 0.133 A:P08263:0.133
 HOH
 2.756
 OD1
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 ASP A:61 A:61 85.0 0.567 T 63.9 32.0 57.0 0.38 0.187 B:P09210:0.187
 HOH
 2.525
 OD1
 O
ASP B:61 B:61 78.0 0.52 T 51.5 40.7 54.0 0.36 0.16 A:P09210:0.16
 HOH
 2.750
 N
 O
ASP C:61 C:61 87.0 0.58 T 55.2 43.9 NA NA NA
ASP D:61 D:61 80.0 0.533 T 45.3 49.4 NA NA NA
ASP E:61 E:61 76.0 0.507 T 43.2 37.8 NA NA NA
ASP F:61 F:61 65.0 0.433 T 48.0 55.6 NA NA NA
ASP G:61 G:61 72.0 0.48 T 47.7 45.1 NA NA NA
ASP H:61 H:61 77.0 0.513 T 48.2 53.4 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 ASP A:61 A:61 68.0 0.453 T 49.7 39.4 45.0 0.3 0.153 B:P09210:0.153
 HOH
 2.971
 N
 O
ASP B:61 B:61 94.0 0.627 T 66.4 42.5 69.0 0.46 0.167 A:P09210:0.167
 HOH
 2.845
 OD1
 O
ASP C:61 C:61 82.0 0.547 T 58.6 30.4 NA NA NA
ASP D:61 D:61 80.0 0.533 T 44.9 42.2 NA NA NA
ASP E:61 E:61 76.0 0.507 T 44.9 47.4 NA NA NA
ASP F:61 F:61 81.0 0.54 T 53.6 27.5 NA NA NA
ASP G:61 G:61 77.0 0.513 T 57.5 52.5 NA NA NA
ASP H:61 H:61 94.0 0.627 T 48.4 48.5 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ASP A:61 A:61 61.0 0.407 T 49.1 46.4 35.0 0.233 0.174 B:P08263:0.173
 HOH
 2.440
 N
 O
ASP B:61 B:61 72.0 0.48 T 44.7 43.9 53.0 0.353 0.127 A:P08263:0.127
 HOH
 9.471
 OD2
 O
ASP C:61 C:61 65.0 0.433 T 40.3 46.5 NA NA NA
ASP D:61 D:61 81.0 0.54 T 48.5 45.6 NA NA NA
ASP E:61 E:61 79.0 0.527 T 60.2 45.2 NA NA NA
ASP F:61 F:61 81.0 0.54 T 47.4 48.1 NA NA NA
ASP G:61 G:61 76.0 0.507 T 44.3 44.3 NA NA NA
ASP H:61 H:61 69.0 0.46 T 35.0 48.5 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 ASP A:61 A:61 69.0 0.46 T 43.1 48.4 45.0 0.3 0.16 B:P08263:0.16
 HOH
 2.948
 N
 O
ASP B:61 B:61 77.0 0.513 T 54.7 39.5 58.0 0.387 0.126 A:P08263:0.127
 HOH
 8.389
 OD1
 O
ASP C:61 C:61 63.0 0.42 T 49.8 44.7 NA NA NA
ASP D:61 D:61 77.0 0.513 T 44.8 39.7 NA NA NA
ASP E:61 E:61 70.0 0.467 T 47.2 50.8 NA NA NA
ASP F:61 F:61 90.0 0.6 T 44.0 44.0 NA NA NA
ASP G:61 G:61 64.0 0.427 T 44.0 46.9 NA NA NA
ASP H:61 H:61 66.0 0.44 T 49.3 41.9 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 ASP A:61 A:61 65.0 0.433 T 48.3 50.5 44.0 0.293 0.14 B:P08263:0.14
ASP B:61 B:61 63.0 0.42 T 47.7 44.4 41.0 0.273 0.147 A:P08263:0.147
ASP C:61 C:61 59.0 0.393 T 38.2 51.5 NA NA NA
ASP D:61 D:61 75.0 0.5 T 35.3 49.9 NA NA NA
ASP E:61 E:61 57.0 0.38 T 45.5 41.5 NA NA NA
ASP F:61 F:61 79.0 0.527 T 40.9 45.7 NA NA NA
ASP G:61 G:61 40.0 0.267 T 44.0 42.0 NA NA NA
ASP H:61 H:61 76.0 0.507 T 33.1 46.7 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 ASP A:61 A:61 90.0 0.6 T 56.4 50.6 67.0 0.447 0.153 B:P09210:0.153
 HOH
 2.999
 N
 O
ASP B:61 B:61 86.0 0.573 T 52.7 31.6 66.0 0.44 0.133 A:P09210:0.133
 HOH
 2.840
 CG
 O
ASP C:61 C:61 88.0 0.587 T 40.2 50.3 NA NA NA
ASP D:61 D:61 83.0 0.553 T 54.1 34.7 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 ASP A:61 A:61 86.0 0.573 T 46.3 45.8 62.0 0.413 0.16 B:Q16772:0.16
 HOH
 2.861
 N
 O
ASP B:61 B:61 82.0 0.547 T 45.9 48.9 59.0 0.393 0.154 A:Q16772:0.153
 HOH
 2.920
 N
 O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 ASP A:61 A:61 84.0 0.56 T 45.5 45.9 63.0 0.42 0.14 B:Q16772:0.14
 HOH
 2.920
 N
 O
ASP B:61 B:61 89.0 0.593 T 40.9 47.4 77.0 0.513 0.08 A:Q16772:0.08
 HOH
 2.801
 N
 O
ASP C:61 C:61 96.0 0.64 T 51.9 43.2 NA NA NA
ASP D:61 D:61 91.0 0.607 T 51.7 45.6 NA NA NA
ASP E:61 E:61 87.0 0.58 T 45.6 52.1 NA NA NA
ASP F:61 F:61 90.0 0.6 T 49.4 44.5 NA NA NA
ASP G:61 G:61 90.0 0.6 T 57.0 39.0 NA NA NA
ASP H:61 H:61 91.0 0.607 T 47.7 48.8 NA NA NA
ASP I:61 I:61 85.0 0.567 T 48.9 42.2 NA NA NA
ASP J:61 J:61 92.0 0.613 T 48.8 44.2 NA NA NA
ASP K:61 K:61 87.0 0.58 T 45.0 47.2 NA NA NA
ASP L:61 L:61 89.0 0.593 T 49.4 46.9 NA NA NA
ASP M:61 M:61 90.0 0.6 T 48.3 45.5 NA NA NA
ASP N:61 N:61 91.0 0.607 T 48.7 48.3 NA NA NA
ASP O:61 O:61 80.0 0.533 T 44.9 49.4 NA NA NA
ASP P:61 P:61 92.0 0.613 T 44.4 45.3 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 ASP A:61 A:61 82.0 0.547 T 48.7 47.6 63.0 0.42 0.127 A:M9ZT87:0.127
 EDO
EDO
HOH
 6.275
3.401
3.148
 OD2
CB
N
 O2
C1
O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 ASP A:61 B:61 73.0 0.487 T 52.1 42.8 53.0 0.353 0.134 B:M9ZT87:0.133
 HOH
 4.128
 OD1
 O
ASP B:61 A:61 71.0 0.473 T 51.6 42.6 51.0 0.34 0.133 A:M9ZT87:0.133
 HOH
 2.823
 N
 O
ASP C:61 D:61 75.0 0.5 T 50.9 41.4 NA NA NA
ASP D:61 C:61 72.0 0.48 T 51.8 42.3 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ASP A:61 A:61 83.0 0.553 T 57.0 46.5 62.0 0.413 0.14 B:P08263+P04903:0.14
 HOH
 3.289
 N
 O
ASP B:61 B:61 73.0 0.487 T 36.9 39.8 61.0 0.407 0.08 A:P08263+P04903:0.08
 HOH
 8.668
 OD2
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 ASP A:61 A:61 82.0 0.547 T 50.6 43.5 65.0 0.433 0.114 A:P08263+P04903:0.113
 HOH
 2.867
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 ASP A:61 A:61 75.0 0.5 T 50.7 41.1
af-p09210-f1 1 P09210 95.05 1e-154 ASP A:61 A:61 77.0 0.513 T 50.7 41.0
af-q16772-f1 1 Q16772 90.54 2e-146 ASP A:61 A:61 57.0 0.38 T 50.6 38.6
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 ASP A:61 A:61 78.0 0.52 T 50.7 40.2