Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52661100 . A C CCDS4945.1:NM_145740.3:c.152aTg>aGg_NP_665683.1:p.51M>R Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 MET A:51 A:51 136.0 0.735 T -52.9 -42.3 32.0 0.173 0.562 B:P08263:0.562
 GSH
HOH
 9.925
2.730
 N
O
 O2
O
MET B:51 B:51 134.0 0.724 T -55.2 -42.9 35.0 0.189 0.535 A:P08263:0.535
 GSH
HOH
 9.876
2.682
 N
O
 O2
O
1pkz 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 MET A:51 A:51 139.0 0.751 T -51.7 -39.8 33.0 0.178 0.573 B:P08263:0.573
 HOH
 2.696
 O
 O
MET B:51 B:51 144.0 0.778 T -50.2 -44.2 44.0 0.238 0.54 A:P08263:0.541
 HOH
 2.819
 O
 O
1pl1 1 P08263 100.0 3e-163 X-RAY
 2004-06-22 MET A:51 A:51 139.0 0.751 T -53.9 -39.7 31.0 0.168 0.583 B:P08263:0.584
 ABY
HOH
 9.871
2.804
 N
O
 O2
O
MET B:51 B:51 135.0 0.73 T -49.4 -40.4 34.0 0.184 0.546 A:P08263:0.546
 ABY
HOH
 9.883
2.721
 N
O
 O2
O
6yaw 1 P08263 100.0 3e-163 X-RAY
 2020-08-26 MET A:51 A:51 143.0 0.773 T -54.2 -42.4 35.0 0.189 0.584 B:P08263:0.584
 P9H
HOH
 9.920
2.835
 C
N
 O5
O
MET B:51 B:51 142.0 0.768 T -52.7 -41.3 44.0 0.238 0.53 A:P08263:0.53
 HOH
 2.864
 N
 O
2r6k 1 P08263 99.55 5e-163 X-RAY
 2008-08-19 MET A:51 A:51 140.0 0.757 T -58.7 -44.9 36.0 0.195 0.562 B:P08263:0.562
 GTX
HOH
 9.868
3.604
 N
O
 O2
O
MET B:51 B:51 140.0 0.757 T -58.7 -35.3 35.0 0.189 0.568 A:P08263:0.568
 GTX
HOH
 9.574
3.369
 N
CG
 O11
O
3zfl 1 P08263 99.55 2e-162 X-RAY
 2012-12-19 MET A:51 A:51 139.0 0.751 T -58.1 -45.2 36.0 0.195 0.556 B:P08263:0.557
 HOH
 2.839
 O
 O
MET B:51 B:51 142.0 0.768 T -61.1 -39.5 38.0 0.205 0.563 A:P08263:0.562
 HOH
 2.744
 O
 O
3u6v 1 P08263 99.55 2e-162 X-RAY
 2011-10-26 MET A:51 A:51 138.0 0.746 T -56.9 -48.3 37.0 0.2 0.546 B:P08263:0.546
 HOH
 3.017
 SD
 O
MET B:51 B:51 145.0 0.784 T -62.1 -39.5 36.0 0.195 0.589 A:P08263:0.589
 HOH
 2.742
 O
 O
1gsd 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 MET A:50 A:51 144.0 0.778 T -50.9 -42.5 48.0 0.259 0.519 B:P08263:0.519
 HOH
 3.045
 O
 O
MET B:50 B:51 144.0 0.778 T -50.9 -42.6 49.0 0.265 0.513 A:P08263:0.514
 HOH
 3.152
 N
 O
MET C:50 C:51 144.0 0.778 T -50.9 -42.5 NA NA NA
MET D:50 D:51 143.0 0.773 T -50.9 -42.5 NA NA NA
1gsf 1 P08263 100.0 3e-162 X-RAY
 1995-09-15 MET A:50 A:51 137.0 0.741 T -54.1 -43.6 53.0 0.286 0.455 B:P08263:0.454
 HOH
 3.130
 N
 O
MET B:50 B:51 139.0 0.751 T -54.1 -43.7 53.0 0.286 0.465 A:P08263:0.465
 HOH
 3.041
 O
 O
MET C:50 C:51 138.0 0.746 T -54.1 -43.6 NA NA NA
MET D:50 D:51 137.0 0.741 T -54.1 -43.7 NA NA NA
1guh 1 P08263 100.0 3e-162 X-RAY
 1993-10-31 MET A:50 A:51 144.0 0.778 T -55.5 -37.4 38.0 0.205 0.573 B:P08263:0.573
 GSB
 9.877
 C
 O31
MET B:50 B:51 141.0 0.762 T -55.5 -37.3 38.0 0.205 0.557 A:P08263:0.557
 GSB
 9.877
 C
 O31
MET C:50 C:51 141.0 0.762 T -55.4 -37.4 NA NA NA
MET D:50 D:51 139.0 0.751 T -55.4 -37.3 NA NA NA
1k3l 1 P08263 100.0 3e-162 X-RAY
 2002-10-23 MET A:50 A:51 139.0 0.751 T -58.2 -38.9 38.0 0.205 0.546 B:P08263:0.546
 GTX
HOH
 9.882
2.673
 N
O
 O2
O
MET B:50 B:51 145.0 0.784 T -58.8 -38.5 40.0 0.216 0.568 A:P08263:0.568
 GTX
HOH
 9.894
2.749
 N
O
 O2
O
1k3o 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 MET A:50 A:51 144.0 0.778 T -52.5 -39.4 54.0 0.292 0.486 B:P08263:0.486
 HOH
 2.819
 O
 O
MET B:50 B:51 148.0 0.8 T -52.4 -36.4 59.0 0.319 0.481 A:P08263:0.481
 HOH
 2.737
 O
 O
1k3y 1 P08263 100.0 3e-162 X-RAY
 2002-10-30 MET A:50 A:51 145.0 0.784 T -56.2 -39.2 39.0 0.211 0.573 B:P08263:0.573
 GTX
HOH
 9.894
2.740
 N
O
 O2
O
MET B:50 B:51 140.0 0.757 T -53.5 -40.4 50.0 0.27 0.487 A:P08263:0.486
 GTX
HOH
 9.908
2.725
 N
O
 O2
O
6ato 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 MET A:50 A:51 141.0 0.762 T -54.9 -41.4 141.0 0.762 0.0 GSH
MPD
MPD
HOH
 9.921
5.877
5.936
2.787
 N
SD
O
O
 O2
HM2
HM2
O
MET B:50 B:51 139.0 0.751 T -56.4 -41.1 NA NA NA
6atp 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 MET A:50 A:51 140.0 0.757 T -55.9 -42.6 140.0 0.757 0.0 MPD
MPD
HOH
 5.977
5.454
2.700
 O
CB
O
 HM1
H12
O
MET B:50 B:51 140.0 0.757 T -56.5 -40.3 NA NA NA
6atq 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 MET A:50 A:51 139.0 0.751 T -54.0 -43.7 139.0 0.751 0.0 MPD
HOH
 5.946
2.764
 SD
O
 H13
O
MET B:50 B:51 145.0 0.784 T -55.0 -39.1 NA NA NA
6atr 1 P08263 100.0 3e-162 X-RAY
 2018-09-12 MET A:50 A:51 140.0 0.757 T -55.5 -41.7 140.0 0.757 0.0 BWS
GSN
EDO
EDO
HOH
 9.928
9.944
3.222
4.052
2.711
 N
N
CA
CB
O
 OAP
OAP
H22
HO2
O
MET B:50 B:51 140.0 0.757 T -55.1 -43.2 NA NA NA
3zfb 1 P08263 99.55 3e-162 X-RAY
 2012-12-19 MET A:51 A:51 137.0 0.741 T -48.8 -46.6 33.0 0.178 0.563 B:P08263:0.562
 HOH
 2.744
 O
 O
MET B:51 B:51 140.0 0.757 T -59.3 -37.0 37.0 0.2 0.557 A:P08263:0.557
 HOH
 2.825
 O
 O
1ydk 1 P08263 99.55 3e-162 X-RAY
 2005-06-07 MET A:51 A:51 137.0 0.741 T -54.1 -44.5 33.0 0.178 0.563 B:P08263:0.562
 GTX
HOH
 9.882
2.831
 N
N
 O2
O
MET B:51 B:51 139.0 0.751 T -55.5 -42.6 38.0 0.205 0.546 A:P08263:0.546
 GTX
HOH
 9.886
2.687
 N
O
 O2
O
1pl2 1 P08263 99.55 4e-162 X-RAY
 2004-06-22 MET A:51 A:51 139.0 0.751 T -54.2 -40.7 33.0 0.178 0.573 B:P08263:0.573
 ABY
HOH
 9.832
2.749
 N
O
 O2
O
MET B:51 B:51 137.0 0.741 T -51.0 -41.1 35.0 0.189 0.552 A:P08263:0.551
 ABY
HOH
 9.913
2.658
 N
O
 O2
O
2r3x 1 P08263 99.55 5e-162 X-RAY
 2007-12-18 MET A:51 A:51 142.0 0.768 T -58.1 -38.1 41.0 0.222 0.546 B:P08263:0.546
 GTX
HOH
 9.879
2.755
 N
O
 O2
O
MET B:51 B:51 141.0 0.762 T -55.6 -42.7 38.0 0.205 0.557 A:P08263:0.557
 GTX
HOH
 9.880
2.670
 N
O
 O2
O
1gse 1 P08263 99.55 1e-161 X-RAY
 1995-09-15 MET A:50 A:51 142.0 0.768 T -54.2 -41.9 39.0 0.211 0.557 B:P08263:0.557
 HOH
 2.897
 O
 O
MET B:50 B:51 145.0 0.784 T -51.0 -46.7 44.0 0.238 0.546 A:P08263:0.546
 HOH
 2.727
 O
 O
3q74 1 P08263 99.55 1e-161 X-RAY
 2011-01-12 MET A:50 A:51 133.0 0.719 T -57.3 -37.6 49.0 0.265 0.454 B:P08263:0.454
 HOH
 2.842
 O
 O
MET B:50 B:51 135.0 0.73 T -49.6 -44.0 34.0 0.184 0.546 A:P08263:0.546
 HOH
 2.674
 O
 O
3ktl 1 P08263 99.55 2e-161 X-RAY
 2009-12-22 MET A:50 A:51 136.0 0.735 T -55.3 -38.9 34.0 0.184 0.551 B:P08263:0.551
 HOH
 2.805
 O
 O
MET B:50 B:51 138.0 0.746 T -57.7 -36.6 37.0 0.2 0.546 A:P08263:0.546
 GTX
HOH
 9.897
3.004
 N
O
 O2
O
1usb 1 P08263 99.55 2e-161 X-RAY
 2004-09-01 MET A:54 A:51 136.0 0.735 T -52.6 -41.9 33.0 0.178 0.557 B:P08263:0.557
 HOH
 2.685
 O
 O
MET B:54 B:51 139.0 0.751 T -63.9 -37.0 41.0 0.222 0.529 A:P08263:0.53
 GSH
HOH
 9.706
2.585
 N
O
 O2
O
3l0h 1 P08263 99.55 3e-161 X-RAY
 2010-01-12 MET A:51 A:51 142.0 0.768 T -49.4 -51.4 38.0 0.205 0.563 B:P08263:0.562
 GTX
HOH
 9.950
2.710
 N
O
 O2
O
MET B:51 B:51 144.0 0.778 T -55.5 -49.6 38.0 0.205 0.573 A:P08263:0.573
 GTX
HOH
 9.893
3.137
 N
N
 O11
O
1xwg 1 P08263 99.55 4e-161 X-RAY
 2005-11-01 MET A:50 A:51 135.0 0.73 T -53.0 -41.4 32.0 0.173 0.557 B:P08263:0.557
 HOH
 2.716
 O
 O
MET B:50 B:51 138.0 0.746 T -51.7 -41.7 37.0 0.2 0.546 A:P08263:0.546
 HOH
 2.681
 O
 O
5jcu 1 P08263 99.55 1e-160 X-RAY
 2016-10-12 MET A:50 A:51 137.0 0.741 T -56.8 -35.4 36.0 0.195 0.546 B:P08263:0.546
 HOH
 2.917
 O
 O
MET B:50 B:51 140.0 0.757 T -51.1 -44.1 39.0 0.211 0.546 A:P08263:0.546
 GVX
HOH
 9.940
2.801
 N
O
 O13
O
MET C:50 C:51 139.0 0.751 T -55.1 -42.6 NA NA NA
MET D:50 D:51 137.0 0.741 T -55.6 -43.0 NA NA NA
4hj2 1 P08263 100.0 4e-159 X-RAY
 2013-03-27 MET A:48 A:51 139.0 0.751 T -51.0 -43.8 34.0 0.184 0.567 B:P08263:0.568
 LZ6
HOH
 9.876
2.600
 N
O
 O28
O
MET B:48 B:51 142.0 0.768 T -49.3 -36.6 39.0 0.211 0.557 A:P08263:0.557
 HOH
 2.987
 N
 O
2vct 1 P09210 95.05 3e-154 X-RAY
 2008-10-28 MET A:51 A:51 138.0 0.746 T -48.1 -42.7 33.0 0.178 0.568 B:P09210:0.568
 HOH
 2.802
 N
 O
MET B:51 B:51 141.0 0.762 T -57.7 -31.0 41.0 0.222 0.54 A:P09210:0.541
 HOH
 2.487
 O
 O
MET C:51 C:51 142.0 0.768 T -46.3 -42.1 NA NA NA
MET D:51 D:51 139.0 0.751 T -48.1 -36.8 NA NA NA
MET E:51 E:51 144.0 0.778 T -53.6 -44.4 NA NA NA
MET F:51 F:51 143.0 0.773 T -53.2 -43.4 NA NA NA
MET G:51 G:51 140.0 0.757 T -50.3 -36.9 NA NA NA
MET H:51 H:51 142.0 0.768 T -44.8 -44.6 NA NA NA
2wju 1 P09210 95.05 3e-154 X-RAY
 2009-06-09 MET A:51 A:51 143.0 0.773 T -51.4 -40.4 36.0 0.195 0.578 B:P09210:0.578
 GSH
HOH
 9.680
2.997
 N
N
 O12
O
MET B:51 B:51 134.0 0.724 T -55.6 -41.7 36.0 0.195 0.529 A:P09210:0.53
 GSH
HOH
 9.725
3.047
 C
N
 CB1
O
MET C:51 C:51 138.0 0.746 T -58.2 -35.2 NA NA NA
MET D:51 D:51 142.0 0.768 T -50.2 -45.8 NA NA NA
MET E:51 E:51 138.0 0.746 T -58.8 -39.9 NA NA NA
MET F:51 F:51 138.0 0.746 S -68.3 -42.0 NA NA NA
MET G:51 G:51 137.0 0.741 T -54.5 -43.1 NA NA NA
MET H:51 H:51 137.0 0.741 T -47.3 -47.5 NA NA NA
3i69 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 MET A:51 A:51 148.0 0.8 T -53.5 -36.2 42.0 0.227 0.573 B:P08263:0.573
 HOH
 2.568
 O
 O
MET B:51 B:51 140.0 0.757 T -60.3 -29.0 36.0 0.195 0.562 A:P08263:0.562
 HOH
 3.872
 N
 O
MET C:51 C:51 146.0 0.789 T -51.8 -35.8 NA NA NA
MET D:51 D:51 141.0 0.762 T -53.7 -31.1 NA NA NA
MET E:51 E:51 143.0 0.773 T -57.9 -42.8 NA NA NA
MET F:51 F:51 147.0 0.795 T -48.3 -45.4 NA NA NA
MET G:51 G:51 145.0 0.784 T -55.2 -41.0 NA NA NA
MET H:51 H:51 142.0 0.768 T -64.2 -39.0 NA NA NA
3i6a 1 P08263 94.12 7e-152 X-RAY
 2009-09-01 MET A:51 A:51 147.0 0.795 T -50.2 -45.8 43.0 0.232 0.563 B:P08263:0.562
 GSH
HOH
 9.862
2.615
 N
O
 O2
O
MET B:51 B:51 134.0 0.724 T -56.7 -35.9 38.0 0.205 0.519 A:P08263:0.519
 GSH
HOH
 9.901
2.876
 N
O
 O2
O
MET C:51 C:51 147.0 0.795 T -50.6 -46.4 NA NA NA
MET D:51 D:51 136.0 0.735 T -52.2 -37.2 NA NA NA
MET E:51 E:51 143.0 0.773 T -55.6 -46.8 NA NA NA
MET F:51 F:51 142.0 0.768 T -63.2 -41.6 NA NA NA
MET G:51 G:51 140.0 0.757 T -50.2 -44.1 NA NA NA
MET H:51 H:51 138.0 0.746 T -57.6 -38.6 NA NA NA
3ik9 1 P08263 94.12 7e-152 X-RAY
 2010-06-23 MET A:51 A:51 139.0 0.751 T -48.4 -42.4 40.0 0.216 0.535 B:P08263:0.535
 BOB
HOH
 9.860
3.750
 C
N
 O31
O
MET B:51 B:51 140.0 0.757 T -54.2 -33.6 39.0 0.211 0.546 A:P08263:0.546
 BOB
HOH
 9.575
3.761
 C
N
 O32
O
MET C:51 C:51 150.0 0.811 T -41.3 -44.9 NA NA NA
MET D:51 D:51 140.0 0.757 T -53.6 -34.8 NA NA NA
MET E:51 E:51 143.0 0.773 T -48.4 -42.2 NA NA NA
MET F:51 F:51 147.0 0.795 T -54.5 -38.7 NA NA NA
MET G:51 G:51 134.0 0.724 T -44.3 -39.1 NA NA NA
MET H:51 H:51 138.0 0.746 T -52.7 -41.5 NA NA NA
4acs 1 P09210 93.67 8e-150 X-RAY
 2011-12-28 MET A:51 A:51 142.0 0.768 T -54.7 -37.6 37.0 0.2 0.568 B:P09210:0.568
 HOH
 2.503
 O
 O
MET B:51 B:51 140.0 0.757 T -34.0 -45.7 41.0 0.222 0.535 A:P09210:0.535
 GSH
HOH
 9.764
2.326
 N
O
 O12
O
MET C:51 C:51 146.0 0.789 T -56.6 -40.4 NA NA NA
MET D:51 D:51 139.0 0.751 T -38.2 -53.1 NA NA NA
1tdi 1 Q16772 90.54 6e-146 X-RAY
 2005-01-18 MET A:51 A:51 151.0 0.816 T -46.0 -41.1 47.0 0.254 0.562 B:Q16772:0.562
 HOH
 2.598
 O
 O
MET B:51 B:51 150.0 0.811 T -47.0 -38.9 48.0 0.259 0.552 A:Q16772:0.551
 GSH
HOH
 9.919
2.692
 C
O
 O31
O
2vcv 1 Q16772 90.54 6e-146 X-RAY
 2008-10-28 MET A:51 A:51 145.0 0.784 T -55.3 -47.2 48.0 0.259 0.525 B:Q16772:0.524
 GSH
HOH
 9.872
2.583
 N
O
 O12
O
MET B:51 B:51 145.0 0.784 T -53.5 -43.3 44.0 0.238 0.546 A:Q16772:0.546
 GSH
HOH
 9.896
2.853
 C
O
 CB1
O
MET C:51 C:51 144.0 0.778 T -54.5 -36.7 NA NA NA
MET D:51 D:51 145.0 0.784 T -49.8 -50.0 NA NA NA
MET E:51 E:51 149.0 0.805 T -49.5 -43.6 NA NA NA
MET F:51 F:51 149.0 0.805 T -54.3 -46.2 NA NA NA
MET G:51 G:51 148.0 0.8 T -54.1 -39.9 NA NA NA
MET H:51 H:51 149.0 0.805 T -56.4 -41.7 NA NA NA
MET I:51 I:51 147.0 0.795 T -50.4 -46.7 NA NA NA
MET J:51 J:51 146.0 0.789 T -58.1 -40.8 NA NA NA
MET K:51 K:51 146.0 0.789 T -53.0 -42.6 NA NA NA
MET L:51 L:51 147.0 0.795 T -49.8 -45.5 NA NA NA
MET M:51 M:51 147.0 0.795 T -53.1 -46.3 NA NA NA
MET N:51 N:51 146.0 0.789 T -52.6 -42.4 NA NA NA
MET O:51 O:51 148.0 0.8 T -44.8 -47.3 NA NA NA
MET P:51 P:51 150.0 0.811 T -59.0 -40.2 NA NA NA
6zj9 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 MET A:51 A:51 152.0 0.822 T -56.4 -36.8 46.0 0.249 0.573 A:M9ZT87:0.573
 GSH
HOH
 9.992
2.895
 N
N
 O2
O
6zjc 1 M9ZT87 80.18 2e-132 X-RAY
 2020-11-18 MET A:51 B:51 148.0 0.8 T -47.2 -39.0 46.0 0.249 0.551 B:M9ZT87:0.551
 GSH
HOH
 9.895
3.897
 N
N
 O2
O
MET B:51 A:51 151.0 0.816 T -51.3 -38.9 48.0 0.259 0.557 A:M9ZT87:0.557
 GSH
HOH
 9.860
3.864
 N
N
 O2
O
MET C:51 D:51 151.0 0.816 T -47.5 -39.9 NA NA NA
MET D:51 C:51 147.0 0.795 T -49.5 -38.6 NA NA NA
5lcz 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 MET A:51 A:51 139.0 0.751 T -55.8 -37.2 34.0 0.184 0.567 B:P08263+P04903:0.568
 GSH
HOH
 9.656
2.354
 N
SD
 O2
O
MET B:51 B:51 147.0 0.795 T -42.9 -38.3 57.0 0.308 0.487 A:P08263+P04903:0.486
 HOH
 3.893
 N
 O
5ld0 1 P08263,P04903 83.78 2e-132 X-RAY
 2016-09-21 MET A:51 A:51 134.0 0.724 T -56.4 -41.4 35.0 0.189 0.535 A:P08263+P04903:0.535
 HOH
 2.736
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08263-f1 1 P08263 100.0 1e-163 MET A:51 A:51 143.0 0.773 T -50.6 -39.2
af-p09210-f1 1 P09210 95.05 1e-154 MET A:51 A:51 144.0 0.778 T -51.1 -40.0
af-q16772-f1 1 Q16772 90.54 2e-146 MET A:51 A:51 142.0 0.768 T -50.1 -40.6
af-q7rtv2-f1 1 Q7RTV2 90.09 6e-146 LEU A:51 A:51 129.0 0.759 T -54.2 -39.7