Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52696737 . G A CCDS4946.1:NM_153699.1:c.578aCg>aTg_NP_714543.1:p.193T>M Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 THR A:193 A:193 50.0 0.357 H -67.3 -44.1 50.0 0.357 0.0 HOH
 2.733
 O
 O
THR B:193 B:193 48.0 0.343 H -64.8 -40.2 48.0 0.343 0.0 HOH
 2.622
 O
 O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 THR A:193 A:193 49.0 0.35 H -64.1 -49.2 49.0 0.35 0.0 HOH
 2.839
 OG1
 O
THR B:193 B:193 48.0 0.343 H -64.6 -42.8 48.0 0.343 0.0 HOH
 2.818
 OG1
 O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 THR A:193 A:193 51.0 0.364 H -62.8 -44.1 51.0 0.364 0.0 HOH
 2.789
 O
 O
THR B:193 B:193 51.0 0.364 H -65.2 -40.7 51.0 0.364 0.0 HOH
 2.689
 O
 O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 THR A:193 A:193 50.0 0.357 H -71.0 -42.8 50.0 0.357 0.0 HOH
 2.909
 OG1
 O
THR B:193 B:193 54.0 0.386 H -67.8 -37.1 54.0 0.386 0.0 HOH
 2.633
 O
 O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 THR A:193 A:193 46.0 0.329 H -67.9 -38.5 46.0 0.329 0.0
THR B:193 B:193 51.0 0.364 H -73.8 -39.2 51.0 0.364 0.0 HOH
 2.732
 OG1
 O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 THR A:193 A:193 45.0 0.321 H -64.1 -45.5 45.0 0.321 0.0 HOH
 2.830
 O
 O
THR B:193 B:193 51.0 0.364 H -61.0 -42.6 51.0 0.364 0.0 HOH
 2.676
 O
 O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 THR A:193 A:193 52.0 0.371 H -67.7 -35.4 52.0 0.371 0.0 HOH
 2.647
 O
 O
THR B:193 B:193 50.0 0.357 H -67.9 -41.2 50.0 0.357 0.0 HOH
 2.263
 O
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 THR A:192 A:193 49.0 0.35 H -62.7 -43.5 49.0 0.35 0.0 HOH
 2.588
 O
 O
THR B:192 B:193 41.0 0.293 H -64.9 -45.2 41.0 0.293 0.0 HOH
 2.909
 OG1
 O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 THR A:192 A:193 42.0 0.3 H -70.8 -38.8 42.0 0.3 0.0 HOH
 4.944
 O
 O
THR B:192 B:193 42.0 0.3 H -70.8 -38.8 42.0 0.3 0.0 HOH
 4.944
 O
 O
THR C:192 C:193 43.0 0.307 H -70.9 -38.8 NA NA NA
THR D:192 D:193 43.0 0.307 H -70.8 -38.8 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 THR A:192 A:193 51.0 0.364 H -70.7 -42.0 51.0 0.364 0.0 HOH
 2.974
 O
 O
THR B:192 B:193 52.0 0.371 H -70.6 -42.0 52.0 0.371 0.0 HOH
 2.974
 O
 O
THR C:192 C:193 52.0 0.371 H -70.6 -42.0 NA NA NA
THR D:192 D:193 51.0 0.364 H -70.6 -42.1 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 THR A:192 A:193 47.0 0.336 H -73.4 -40.9 47.0 0.336 0.0
THR B:192 B:193 46.0 0.329 H -73.4 -40.8 46.0 0.329 0.0
THR C:192 C:193 46.0 0.329 H -73.3 -41.0 NA NA NA
THR D:192 D:193 46.0 0.329 H -73.4 -40.8 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 THR A:192 A:193 45.0 0.321 H -70.3 -37.8 45.0 0.321 0.0 HOH
 2.844
 O
 O
THR B:192 B:193 49.0 0.35 H -71.5 -39.6 49.0 0.35 0.0 HOH
 2.846
 OG1
 O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 THR A:192 A:193 55.0 0.393 H -56.9 -44.6 55.0 0.393 0.0 HOH
 3.050
 N
 O
THR B:192 B:193 42.0 0.3 H -73.3 -34.2 42.0 0.3 0.0 HOH
 6.167
 N
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 THR A:192 A:193 48.0 0.343 H -71.0 -36.9 48.0 0.343 0.0 HOH
 2.827
 O
 O
THR B:192 B:193 49.0 0.35 H -69.1 -38.9 49.0 0.35 0.0 HOH
 2.830
 O
 O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:192 A:193 50.0 0.357 H -68.9 -42.6 50.0 0.357 0.0 HOH
 2.571
 O
 O
THR B:192 B:193 52.0 0.371 H -67.6 -39.9 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:192 A:193 51.0 0.364 H -63.1 -45.0 51.0 0.364 0.0 HOH
 2.750
 O
 O
THR B:192 B:193 51.0 0.364 H -64.5 -43.7 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:192 A:193 52.0 0.371 H -65.5 -38.7 52.0 0.371 0.0 HOH
 2.576
 O
 O
THR B:192 B:193 50.0 0.357 H -58.8 -41.5 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:192 A:193 49.0 0.35 H -66.4 -40.3 49.0 0.35 0.0 EDO
HOH
 8.201
2.828
 O
O
 O1
O
THR B:192 B:193 52.0 0.371 H -67.0 -39.4 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 THR A:193 A:193 49.0 0.35 H -65.2 -34.9 49.0 0.35 0.0 HOH
 2.556
 OG1
 O
THR B:193 B:193 44.0 0.314 H -72.4 -36.9 44.0 0.314 0.0 HOH
 6.668
 CG2
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 THR A:193 A:193 50.0 0.357 H -64.3 -37.2 50.0 0.357 0.0 HOH
 2.953
 OG1
 O
THR B:193 B:193 44.0 0.314 H -60.2 -43.6 44.0 0.314 0.0 HOH
 2.659
 O
 O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 THR A:193 A:193 50.0 0.357 H -62.3 -37.8 50.0 0.357 0.0 HOH
 2.681
 O
 O
THR B:193 B:193 52.0 0.371 H -70.8 -30.5 52.0 0.371 0.0 HOH
 4.064
 CB
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 THR A:193 A:193 51.0 0.364 H -65.9 -41.1 51.0 0.364 0.0 HOH
 2.758
 O
 O
THR B:193 B:193 50.0 0.357 H -66.8 -39.5 50.0 0.357 0.0 HOH
 2.587
 O
 O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 THR A:193 A:193 50.0 0.357 H -81.1 -27.6 50.0 0.357 0.0 HOH
 2.788
 OG1
 O
THR B:193 B:193 53.0 0.379 H -73.7 -41.8 53.0 0.379 0.0 HOH
 2.936
 O
 O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 THR A:192 A:193 50.0 0.357 H -57.2 -42.4 50.0 0.357 0.0 HOH
 2.659
 O
 O
THR B:192 B:193 47.0 0.336 H -65.6 -34.8 47.0 0.336 0.0 HOH
 2.619
 O
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 THR A:192 A:193 46.0 0.329 H -63.8 -39.4 46.0 0.329 0.0 HOH
 2.835
 N
 O
THR B:192 B:193 52.0 0.371 H -63.3 -41.1 52.0 0.371 0.0 HOH
 2.760
 O
 O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 THR A:196 A:193 44.0 0.314 H -62.5 -41.6 44.0 0.314 0.0 HOH
 2.961
 O
 O
THR B:196 B:193 46.0 0.329 H -59.6 -44.6 46.0 0.329 0.0 HOH
 2.668
 O
 O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 THR A:192 A:193 49.0 0.35 H -70.7 -42.7 49.0 0.35 0.0 HOH
 2.745
 O
 O
THR B:192 B:193 50.0 0.357 H -64.7 -38.3 50.0 0.357 0.0 HOH
 2.492
 O
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 THR A:193 A:193 46.0 0.329 H -66.6 -48.0 46.0 0.329 0.0 HOH
 2.645
 O
 O
THR B:193 B:193 48.0 0.343 H -58.9 -43.2 48.0 0.343 0.0 HOH
 2.695
 OG1
 O
THR C:193 C:193 52.0 0.371 H -65.2 -39.9 NA NA NA
THR D:193 D:193 46.0 0.329 H -62.0 -45.0 NA NA NA
THR E:193 E:193 49.0 0.35 H -65.3 -39.5 NA NA NA
THR F:193 F:193 49.0 0.35 H -80.4 -42.3 NA NA NA
THR G:193 G:193 49.0 0.35 H -81.1 -48.3 NA NA NA
THR H:193 H:193 48.0 0.343 H -68.1 -36.1 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 THR A:193 A:193 47.0 0.336 H -79.7 -40.1 47.0 0.336 0.0 HOH
 2.644
 O
 O
THR B:193 B:193 47.0 0.336 H -81.6 -44.3 47.0 0.336 0.0 HOH
 2.708
 O
 O
THR C:193 C:193 46.0 0.329 H -66.6 -45.1 NA NA NA
THR D:193 D:193 47.0 0.336 H -65.5 -35.2 NA NA NA
THR E:193 E:193 45.0 0.321 H -66.5 -51.3 NA NA NA
THR F:193 F:193 49.0 0.35 H -79.4 -42.8 NA NA NA
THR G:193 G:193 50.0 0.357 H -86.3 -45.3 NA NA NA
THR H:193 H:193 39.0 0.279 H -72.3 -43.8 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 THR A:192 A:193 49.0 0.35 H -58.9 -44.9 49.0 0.35 0.0 HOH
 2.828
 OG1
 O
THR B:192 B:193 53.0 0.379 H -63.9 -39.8 53.0 0.379 0.0 HOH
 2.318
 O
 O
THR C:192 C:193 49.0 0.35 H -63.2 -40.5 NA NA NA
THR D:192 D:193 50.0 0.357 H -61.4 -41.5 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 THR A:190 A:193 50.0 0.357 H -63.4 -45.9 50.0 0.357 0.0 HOH
 2.688
 O
 O
THR B:190 B:193 50.0 0.357 H -68.1 -44.2 50.0 0.357 0.0 HOH
 2.890
 OG1
 O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 THR A:193 A:193 40.0 0.286 H -69.2 -30.8 40.0 0.286 0.0 HOH
 2.220
 OG1
 O
THR B:193 B:193 49.0 0.35 H -71.9 -35.3 49.0 0.35 0.0 HOH
 3.207
 O
 O
THR C:193 C:193 45.0 0.321 H -73.0 -39.6 NA NA NA
THR D:193 D:193 45.0 0.321 H -70.9 -38.3 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 THR A:193 A:193 48.0 0.343 H -63.7 -42.2 48.0 0.343 0.0 HOH
 2.809
 OG1
 O
THR B:193 B:193 47.0 0.336 H -62.6 -45.5 47.0 0.336 0.0 HOH
 2.905
 N
 O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 THR A:193 A:193 47.0 0.336 H -68.4 -39.5 47.0 0.336 0.0 HOH
 2.745
 OG1
 O
THR B:193 B:193 48.0 0.343 H -67.0 -40.9 48.0 0.343 0.0 HOH
 2.724
 O
 O
THR C:193 C:193 51.0 0.364 H -64.3 -39.4 NA NA NA
THR D:193 D:193 47.0 0.336 H -66.2 -41.8 NA NA NA
THR E:193 E:193 50.0 0.357 H -74.9 -36.2 NA NA NA
THR F:193 F:193 47.0 0.336 H -72.5 -39.8 NA NA NA
THR G:193 G:193 49.0 0.35 H -76.1 -36.7 NA NA NA
THR H:193 H:193 50.0 0.357 H -66.6 -42.5 NA NA NA
THR I:193 I:193 46.0 0.329 H -65.1 -43.6 NA NA NA
THR J:193 J:193 48.0 0.343 H -69.8 -37.7 NA NA NA
THR K:193 K:193 48.0 0.343 H -71.4 -39.4 NA NA NA
THR L:193 L:193 47.0 0.336 H -61.5 -44.9 NA NA NA
THR M:193 M:193 52.0 0.371 H -59.5 -45.5 NA NA NA
THR N:193 N:193 49.0 0.35 H -67.2 -34.1 NA NA NA
THR O:193 O:193 51.0 0.364 H -57.0 -46.4 NA NA NA
THR P:193 P:193 52.0 0.371 H -60.2 -35.4 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 THR A:193 A:193 51.0 0.364 H -68.7 -44.9 51.0 0.364 0.0 HOH
 7.736
 O
 O
THR B:193 B:193 50.0 0.357 H -62.4 -46.0 50.0 0.357 0.0 HOH
 7.339
 O
 O
THR C:193 C:193 51.0 0.364 H -65.7 -46.1 NA NA NA
THR D:193 D:193 53.0 0.379 H -73.5 -35.6 NA NA NA
THR E:193 E:193 45.0 0.321 H -67.3 -46.3 NA NA NA
THR F:193 F:193 53.0 0.379 H -69.7 -48.4 NA NA NA
THR G:193 G:193 55.0 0.393 H -76.9 -28.0 NA NA NA
THR H:193 H:193 52.0 0.371 H -60.9 -38.6 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 THR A:193 A:193 50.0 0.357 H -62.9 -41.6 50.0 0.357 0.0 HOH
 4.089
 CB
 O
THR B:193 B:193 50.0 0.357 H -65.8 -41.7 50.0 0.357 0.0 HOH
 6.732
 O
 O
THR C:193 C:193 51.0 0.364 H -62.2 -44.3 NA NA NA
THR D:193 D:193 49.0 0.35 H -69.6 -40.0 NA NA NA
THR E:193 E:193 48.0 0.343 H -67.3 -44.1 NA NA NA
THR F:193 F:193 49.0 0.35 H -65.9 -40.7 NA NA NA
THR G:193 G:193 49.0 0.35 H -67.6 -38.6 NA NA NA
THR H:193 H:193 49.0 0.35 H -63.8 -39.9 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 THR A:193 A:193 46.0 0.329 H -58.3 -45.4 46.0 0.329 0.0
THR B:193 B:193 44.0 0.314 H -65.1 -42.3 44.0 0.314 0.0
THR C:193 C:193 52.0 0.371 H -57.7 -44.1 NA NA NA
THR D:193 D:193 46.0 0.329 H -62.3 -42.1 NA NA NA
THR E:193 E:193 51.0 0.364 H -66.3 -43.1 NA NA NA
THR F:193 F:193 53.0 0.379 H -70.1 -39.1 NA NA NA
THR G:193 G:193 55.0 0.393 H -65.2 -41.4 NA NA NA
THR H:193 H:193 52.0 0.371 H -53.7 -39.5 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 ASN A:193 A:193 68.0 0.425 H -63.0 -36.6 68.0 0.425 0.0 HOH
 2.893
 N
 O
ASN B:193 B:193 67.0 0.419 H -63.6 -31.2 67.0 0.419 0.0 HOH
 2.982
 OD1
 O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 ASN A:193 A:193 69.0 0.431 H -69.5 -32.6 69.0 0.431 0.0 HOH
 2.730
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 THR A:193 A:193 51.0 0.364 H -68.7 -46.0
af-p08263-f1 1 P08263 90.09 6e-146 THR A:193 A:193 49.0 0.35 H -68.3 -44.8
af-p09210-f1 1 P09210 88.74 1e-143 THR A:193 A:193 48.0 0.343 H -69.3 -45.0
af-q16772-f1 1 Q16772 85.59 7e-139 THR A:193 A:193 50.0 0.357 H -69.1 -44.7