Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52698962 . G A CCDS4946.1:NM_153699.1:c.391Cgc>Tgc_NP_714543.1:p.131R>C Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ARG A:131 A:131 149.0 0.662 I -114.7 -60.9 45.0 0.2 0.462 B:P08263:0.462
 GSH
HOH
 2.863
2.752
 NH2
O
 O32
O
ARG B:131 B:131 141.0 0.627 I -121.9 -60.5 36.0 0.16 0.467 A:P08263:0.467
 GSH
HOH
 2.843
2.826
 NH2
O
 O32
O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ARG A:131 A:131 149.0 0.662 I -110.7 -65.1 40.0 0.178 0.484 B:P08263:0.484
 HOH
 2.879
 NH1
 O
ARG B:131 B:131 151.0 0.671 I -120.7 -52.6 50.0 0.222 0.449 A:P08263:0.449
 HOH
 2.772
 O
 O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ARG A:131 A:131 149.0 0.662 I -116.5 -59.2 44.0 0.196 0.466 B:P08263:0.467
 ABY
HOH
 2.912
2.777
 NH2
O
 O32
O
ARG B:131 B:131 147.0 0.653 I -117.5 -64.2 42.0 0.187 0.466 A:P08263:0.467
 ABY
HOH
 2.843
2.841
 NH2
O
 O32
O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 ARG A:131 A:131 143.0 0.636 I -127.4 -62.6 38.0 0.169 0.467 B:P08263:0.467
 P9H
HOH
 2.921
2.888
 NH2
NE
 O5
O
ARG B:131 B:131 149.0 0.662 I -113.6 -57.2 48.0 0.213 0.449 A:P08263:0.449
 P9H
HOH
 2.614
2.690
 NH2
NE
 O5
O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 ARG A:131 A:131 144.0 0.64 I -116.9 -59.8 42.0 0.187 0.453 B:P08263:0.453
 GTX
HOH
 2.557
2.745
 NH1
NH1
 O32
O
ARG B:131 B:131 148.0 0.658 I -113.3 -64.2 42.0 0.187 0.471 A:P08263:0.471
 GTX
HOH
 2.792
2.634
 NH1
O
 O32
O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 ARG A:131 A:131 149.0 0.662 I -114.1 -58.3 45.0 0.2 0.462 B:P08263:0.462
 GTX
HOH
 2.865
2.770
 NH2
O
 O31
O
ARG B:131 B:131 147.0 0.653 I -113.5 -65.7 45.0 0.2 0.453 A:P08263:0.453
 GTX
HOH
 2.866
2.678
 NH1
O
 O32
O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 ARG A:131 A:131 145.0 0.644 I -111.8 -70.4 45.0 0.2 0.444 B:P08263:0.444
 HOH
 2.736
 O
 O
ARG B:131 B:131 145.0 0.644 I -123.7 -55.2 41.0 0.182 0.462 A:P08263:0.462
 HOH
 2.573
 NH1
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 ARG A:130 A:131 147.0 0.653 I -122.4 -59.4 37.0 0.164 0.489 B:P08263:0.489
 GSH
EAA
HOH
 2.954
9.599
2.775
 NH2
NH1
O
 O32
C11
O
ARG B:130 B:131 137.0 0.609 I -125.6 -61.3 38.0 0.169 0.44 A:P08263:0.44
 GSH
EAA
HOH
 2.858
9.645
2.704
 NH2
NH1
NH1
 O32
C11
O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 ARG A:130 A:131 135.0 0.6 I -118.9 -61.9 37.0 0.164 0.436 B:P08263:0.436
 HOH
 2.820
 O
 O
ARG B:130 B:131 136.0 0.604 I -118.9 -61.8 36.0 0.16 0.444 A:P08263:0.444
 HOH
 2.820
 O
 O
ARG C:130 C:131 135.0 0.6 I -118.8 -61.9 NA NA NA
ARG D:130 D:131 137.0 0.609 I -118.9 -61.8 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 ARG A:130 A:131 141.0 0.627 I -117.2 -57.1 46.0 0.204 0.423 B:P08263:0.422
 EAA
HOH
 8.752
2.943
 NH1
NH1
 OXT
O
ARG B:130 B:131 142.0 0.631 I -117.2 -57.1 45.0 0.2 0.431 A:P08263:0.431
 EAA
HOH
 8.701
2.943
 NH1
NH1
 OXT
O
ARG C:130 C:131 140.0 0.622 I -117.3 -57.0 NA NA NA
ARG D:130 D:131 143.0 0.636 I -117.2 -57.1 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 ARG A:130 A:131 146.0 0.649 I -110.3 -60.7 40.0 0.178 0.471 B:P08263:0.471
 GSB
 2.828
 NH2
 O32
ARG B:130 B:131 144.0 0.64 I -110.3 -60.8 41.0 0.182 0.458 A:P08263:0.458
 GSB
 2.759
 NH2
 O32
ARG C:130 C:131 142.0 0.631 I -110.3 -60.6 NA NA NA
ARG D:130 D:131 143.0 0.636 I -110.3 -60.8 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 ARG A:130 A:131 150.0 0.667 I -115.3 -60.5 48.0 0.213 0.454 B:P08263:0.453
 GTX
HOH
 2.840
2.784
 NH2
O
 O31
O
ARG B:130 B:131 148.0 0.658 I -124.1 -60.4 44.0 0.196 0.462 A:P08263:0.462
 GTX
HOH
 2.805
2.725
 NH2
O
 O31
O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 ARG A:130 A:131 128.0 0.569 I -113.3 -61.6 44.0 0.196 0.373 B:P08263:0.373
 HOH
 2.823
 NH1
 O
ARG B:130 B:131 135.0 0.6 I -115.5 -57.4 45.0 0.2 0.4 A:P08263:0.4
 HOH
 2.710
 O
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 ARG A:130 A:131 147.0 0.653 I -116.0 -63.9 43.0 0.191 0.462 B:P08263:0.462
 GTX
GOL
HOH
 2.813
9.939
2.841
 NH2
NH1
O
 O31
O1
O
ARG B:130 B:131 145.0 0.644 I -118.6 -60.3 42.0 0.187 0.457 A:P08263:0.458
 GTX
GOL
HOH
 2.826
9.858
2.708
 NH2
NH1
O
 O31
O3
O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ARG A:130 A:131 157.0 0.698 I -122.4 -60.0 157.0 0.698 0.0 HOH
 2.917
 O
 O
ARG B:130 B:131 139.0 0.618 I -123.0 -59.3 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ARG A:130 A:131 142.0 0.631 I -114.9 -58.1 142.0 0.631 0.0 HOH
 2.730
 NH1
 O
ARG B:130 B:131 143.0 0.636 I -113.6 -59.4 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ARG A:130 A:131 143.0 0.636 I -109.9 -57.3 143.0 0.636 0.0 HOH
 2.789
 NH1
 O
ARG B:130 B:131 148.0 0.658 I -114.4 -60.6 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ARG A:130 A:131 149.0 0.662 I -117.1 -59.4 149.0 0.662 0.0 HOH
 2.897
 NE
 O
ARG B:130 B:131 149.0 0.662 I -115.7 -59.0 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 ARG A:131 A:131 148.0 0.658 I -114.9 -62.4 55.0 0.244 0.414 B:P08263:0.413
 HOH
 2.407
 NE
 O
ARG B:131 B:131 141.0 0.627 I -112.0 -62.9 39.0 0.173 0.454 A:P08263:0.453
 HOH
 2.593
 NH1
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 ARG A:131 A:131 152.0 0.676 I -111.3 -63.9 48.0 0.213 0.463 B:P08263:0.462
 GTX
HOH
 2.774
2.687
 NH2
O
 O31
O
ARG B:131 B:131 142.0 0.631 I -113.2 -64.9 36.0 0.16 0.471 A:P08263:0.471
 GTX
HOH
 2.698
2.762
 NH2
O
 O31
O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 ARG A:131 A:131 151.0 0.671 I -115.9 -65.7 52.0 0.231 0.44 B:P08263:0.44
 HOH
 2.484
 NH1
 O
ARG B:131 B:131 148.0 0.658 I -107.1 -61.5 43.0 0.191 0.467 A:P08263:0.467
 HOH
 2.991
 NH2
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 ARG A:131 A:131 145.0 0.644 I -118.5 -60.6 45.0 0.2 0.444 B:P08263:0.444
 ABY
HOH
 2.872
2.825
 NH2
O
 O32
O
ARG B:131 B:131 148.0 0.658 I -115.8 -62.9 44.0 0.196 0.462 A:P08263:0.462
 ABY
HOH
 2.873
2.845
 NH2
NH1
 O32
O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 ARG A:131 A:131 150.0 0.667 I -135.0 -55.4 50.0 0.222 0.445 B:P08263:0.444
 GTX
HOH
 2.978
2.894
 NH2
NE
 O31
O
ARG B:131 B:131 157.0 0.698 I -114.2 -62.0 44.0 0.196 0.502 A:P08263:0.502
 GTX
HOH
 2.776
2.666
 NH1
O
 O32
O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 ARG A:130 A:131 155.0 0.689 I -116.7 -61.1 51.0 0.227 0.462 B:P08263:0.462
 HOH
 2.551
 NH1
 O
ARG B:130 B:131 145.0 0.644 I -117.4 -59.3 47.0 0.209 0.435 A:P08263:0.436
 HOH
 2.553
 NE
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 ARG A:130 A:131 147.0 0.653 I -118.3 -58.5 42.0 0.187 0.466 B:P08263:0.467
 GTX
HOH
 2.645
2.696
 NH2
O
 O31
O
ARG B:130 B:131 150.0 0.667 I -116.5 -63.2 43.0 0.191 0.476 A:P08263:0.476
 GTX
HOH
 2.972
2.755
 NH2
NE
 O31
O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 ARG A:134 A:131 152.0 0.676 I -112.9 -65.1 53.0 0.236 0.44 B:P08263:0.44
 GSH
HOH
 3.038
2.725
 NH2
O
 O31
O
ARG B:134 B:131 147.0 0.653 I -123.9 -63.0 43.0 0.191 0.462 A:P08263:0.462
 GSH
HOH
 2.889
2.994
 NH2
O
 O31
O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 ARG A:130 A:131 148.0 0.658 I -121.0 -54.8 49.0 0.218 0.44 B:P08263:0.44
 HOH
 2.936
 NH1
 O
ARG B:130 B:131 144.0 0.64 I -118.3 -64.7 44.0 0.196 0.444 A:P08263:0.444
 HOH
 2.711
 NE
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 ARG A:131 A:131 139.0 0.618 I -124.1 -61.5 60.0 0.267 0.351 B:P09210:0.351
 ASD
HOH
 9.807
2.712
 NH1
NE
 C19
O
ARG B:131 B:131 173.0 0.769 I -152.1 -60.6 78.0 0.347 0.422 A:P09210:0.422
 HOH
 2.621
 NH1
 O
ARG C:131 C:131 142.0 0.631 I -125.1 -55.2 NA NA NA
ARG D:131 D:131 159.0 0.707 I -125.8 -64.2 NA NA NA
ARG E:131 E:131 145.0 0.644 I -111.3 -60.2 NA NA NA
ARG F:131 F:131 135.0 0.6 I -128.2 -51.9 NA NA NA
ARG G:131 G:131 143.0 0.636 I -96.1 -68.2 NA NA NA
ARG H:131 H:131 156.0 0.693 I -153.7 -66.3 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 ARG A:131 A:131 150.0 0.667 I -114.1 -61.8 43.0 0.191 0.476 B:P09210:0.476
 GSH
HOH
 2.907
2.817
 NH2
NH1
 O32
O
ARG B:131 B:131 139.0 0.618 I -124.4 -65.9 38.0 0.169 0.449 A:P09210:0.449
 GSH
HOH
 2.904
2.988
 NH2
NE
 O32
O
ARG C:131 C:131 150.0 0.667 I -130.5 -58.8 NA NA NA
ARG D:131 D:131 150.0 0.667 I -109.4 -65.4 NA NA NA
ARG E:131 E:131 137.0 0.609 I -118.4 -62.3 NA NA NA
ARG F:131 F:131 146.0 0.649 I -111.9 -58.4 NA NA NA
ARG G:131 G:131 137.0 0.609 I -126.3 -59.3 NA NA NA
ARG H:131 H:131 154.0 0.684 I -119.7 -53.4 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 ARG A:130 A:131 151.0 0.671 I -121.4 -55.5 44.0 0.196 0.475 B:P08263:0.476
 GVX
HOH
 2.774
2.746
 NH2
O
 O18
O
ARG B:130 B:131 145.0 0.644 I -126.3 -64.4 41.0 0.182 0.462 A:P08263:0.462
 GVX
HOH
 2.627
2.515
 NH2
O
 O17
O
ARG C:130 C:131 153.0 0.68 I -118.4 -62.2 NA NA NA
ARG D:130 D:131 142.0 0.631 I -125.5 -55.8 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 ARG A:128 A:131 145.0 0.644 I -111.7 -58.3 43.0 0.191 0.453 B:P08263:0.453
 LZ6
HOH
 2.740
2.625
 NH2
O
 O27
O
ARG B:128 B:131 144.0 0.64 I -124.3 -63.2 44.0 0.196 0.444 A:P08263:0.444
 LZ6
HOH
 2.737
2.971
 NH2
NH1
 O27
O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 ARG A:131 A:131 143.0 0.636 I -112.6 -51.3 41.0 0.182 0.454 B:P09210:0.453
 GSH
HOH
 2.659
2.841
 NH2
O
 O31
O
ARG B:131 B:131 131.0 0.582 I -114.6 -69.3 32.0 0.142 0.44 A:P09210:0.44
 GSH
HOH
 2.857
2.771
 NH2
O
 O31
O
ARG C:131 C:131 144.0 0.64 I -107.2 -55.1 NA NA NA
ARG D:131 D:131 145.0 0.644 I -121.2 -47.6 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 ARG A:131 A:131 133.0 0.591 I -110.6 -65.5 29.0 0.129 0.462 B:Q16772:0.462
 GSH
HOH
 3.105
2.809
 NH2
NH2
 O32
O
ARG B:131 B:131 136.0 0.604 I -108.1 -64.4 32.0 0.142 0.462 A:Q16772:0.462
 GSH
HOH
 3.175
3.979
 NH2
NH2
 O32
O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 ARG A:131 A:131 138.0 0.613 I -117.3 -58.0 37.0 0.164 0.449 B:Q16772:0.449
 GSH
ASD
HOH
 2.815
7.268
2.788
 NH2
NH2
O
 O31
O1
O
ARG B:131 B:131 137.0 0.609 I -112.0 -56.5 33.0 0.147 0.462 A:Q16772:0.462
 GSH
ASD
HOH
 2.642
7.293
2.678
 NH2
NH2
NH2
 O32
O1
O
ARG C:131 C:131 141.0 0.627 I -117.3 -63.7 NA NA NA
ARG D:131 D:131 139.0 0.618 I -112.0 -61.0 NA NA NA
ARG E:131 E:131 130.0 0.578 I -113.2 -59.2 NA NA NA
ARG F:131 F:131 136.0 0.604 I -110.1 -60.8 NA NA NA
ARG G:131 G:131 137.0 0.609 I -106.5 -63.6 NA NA NA
ARG H:131 H:131 137.0 0.609 I -114.6 -57.4 NA NA NA
ARG I:131 I:131 136.0 0.604 I -115.8 -57.0 NA NA NA
ARG J:131 J:131 140.0 0.622 I -111.1 -58.2 NA NA NA
ARG K:131 K:131 139.0 0.618 I -117.7 -59.1 NA NA NA
ARG L:131 L:131 141.0 0.627 I -117.6 -55.6 NA NA NA
ARG M:131 M:131 134.0 0.596 I -119.0 -53.8 NA NA NA
ARG N:131 N:131 129.0 0.573 I -124.5 -53.3 NA NA NA
ARG O:131 O:131 131.0 0.582 I -119.6 -58.5 NA NA NA
ARG P:131 P:131 144.0 0.64 I -119.2 -48.7 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 ARG A:131 A:131 137.0 0.609 I -107.7 -61.8 35.0 0.156 0.453 B:P08263:0.453
 GSH
HOH
 2.884
3.268
 NH2
NE
 O31
O
ARG B:131 B:131 139.0 0.618 I -109.8 -59.3 29.0 0.129 0.489 A:P08263:0.489
 HOH
 4.468
 NH1
 O
ARG C:131 C:131 145.0 0.644 I -116.1 -65.9 NA NA NA
ARG D:131 D:131 153.0 0.68 I -106.4 -51.4 NA NA NA
ARG E:131 E:131 152.0 0.676 I -113.1 -61.2 NA NA NA
ARG F:131 F:131 140.0 0.622 I -110.1 -64.1 NA NA NA
ARG G:131 G:131 141.0 0.627 I -121.2 -63.2 NA NA NA
ARG H:131 H:131 152.0 0.676 I -102.2 -62.2 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 ARG A:131 A:131 141.0 0.627 I -117.9 -59.0 45.0 0.2 0.427 B:P08263:0.427
 GSH
HOH
 2.810
3.008
 NH2
NH1
 O31
O
ARG B:131 B:131 143.0 0.636 I -113.3 -61.4 33.0 0.147 0.489 A:P08263:0.489
 GSH
HOH
 2.681
2.851
 NH2
O
 O32
O
ARG C:131 C:131 149.0 0.662 I -115.7 -61.4 NA NA NA
ARG D:131 D:131 146.0 0.649 I -115.0 -58.1 NA NA NA
ARG E:131 E:131 154.0 0.684 I -111.6 -63.4 NA NA NA
ARG F:131 F:131 144.0 0.64 I -128.3 -57.9 NA NA NA
ARG G:131 G:131 139.0 0.618 I -120.0 -61.5 NA NA NA
ARG H:131 H:131 149.0 0.662 I -100.0 -59.6 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 ARG A:131 A:131 145.0 0.644 I -118.2 -68.4 50.0 0.222 0.422 B:P08263:0.422
 BOB
HOH
 2.527
6.941
 NH2
NH1
 O31
O
ARG B:131 B:131 138.0 0.613 I -119.1 -59.5 42.0 0.187 0.426 A:P08263:0.427
 BOB
HOH
 2.472
6.820
 NH2
NE
 O31
O
ARG C:131 C:131 143.0 0.636 I -123.7 -62.4 NA NA NA
ARG D:131 D:131 139.0 0.618 I -104.6 -65.9 NA NA NA
ARG E:131 E:131 146.0 0.649 I -139.9 -64.3 NA NA NA
ARG F:131 F:131 144.0 0.64 I -118.5 -58.4 NA NA NA
ARG G:131 G:131 137.0 0.609 I -136.5 -59.1 NA NA NA
ARG H:131 H:131 146.0 0.649 I -113.6 -61.9 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 ARG A:131 A:131 125.0 0.556 I -120.9 -58.7 25.0 0.111 0.445 B:P08263+P04903:0.444
 HOH
 4.136
 NH1
 O
ARG B:131 B:131 129.0 0.573 I -115.9 -62.7 25.0 0.111 0.462 A:P08263+P04903:0.462
 GSH
HOH
 2.841
2.951
 NH2
NE
 O32
O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 ARG A:131 A:131 138.0 0.613 I -121.5 -56.3 36.0 0.16 0.453 A:P08263+P04903:0.453
 HOH
 2.655
 NE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 ARG A:131 A:131 143.0 0.636 I -120.1 -62.9
af-p08263-f1 1 P08263 90.09 6e-146 ARG A:131 A:131 138.0 0.613 I -122.6 -61.0
af-p09210-f1 1 P09210 88.74 1e-143 ARG A:131 A:131 140.0 0.622 I -118.7 -59.8
af-q16772-f1 1 Q16772 85.59 7e-139 ARG A:131 A:131 142.0 0.631 I -117.2 -57.4