Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52699055 . C A CCDS4946.1:NM_153699.1:c.298Gta>Tta_NP_714543.1:p.100V>L Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ALA A:100 A:100 30.0 0.261 H -65.4 -42.5 30.0 0.261 0.0 GSH
HED
GSH
HOH
 9.309
3.461
7.171
3.039
 CB
CB
C
O
 O11
C1
N1
O
ALA B:100 B:100 30.0 0.261 H -64.9 -42.3 30.0 0.261 0.0 GSH
GSH
HED
HOH
 7.137
9.473
3.366
2.922
 C
CB
CB
O
 N1
O11
C6
O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ALA A:100 A:100 30.0 0.261 H -69.6 -36.3 30.0 0.261 0.0 HED
HOH
 3.167
2.877
 CB
O
 C1
O
ALA B:100 B:100 28.0 0.243 H -65.3 -40.0 28.0 0.243 0.0 HED
HOH
 3.946
2.737
 CA
O
 C2
O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ALA A:100 A:100 33.0 0.287 H -63.1 -38.5 33.0 0.287 0.0 ABY
HOH
 7.229
2.686
 C
O
 N1
O
ALA B:100 B:100 34.0 0.296 H -65.4 -35.8 34.0 0.296 0.0 ABY
HOH
 7.320
2.907
 C
O
 N1
O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 ALA A:100 A:100 28.0 0.243 H -66.8 -41.2 28.0 0.243 0.0 P9H
GOL
GOL
P9H
HOH
 9.501
5.368
7.209
7.178
3.949
 CB
CB
CB
C
CB
 O2
O1
O2
N1
O
ALA B:100 B:100 32.0 0.278 H -66.3 -26.2 32.0 0.278 0.0 P9H
GOL
GOL
P9H
HOH
 7.360
7.040
5.527
9.458
3.562
 C
CB
O
CB
CB
 N1
O2
O1
O2
O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 ALA A:100 A:100 31.0 0.27 H -64.6 -31.0 31.0 0.27 0.0 GTX
GTX
HOH
 9.486
7.379
3.706
 CB
C
CB
 O12
N1
O
ALA B:100 B:100 32.0 0.278 H -64.7 -32.2 32.0 0.278 0.0 GTX
GTX
HOH
 7.220
9.372
3.547
 C
CB
CB
 N1
O12
O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 ALA A:100 A:100 35.0 0.304 H -53.4 -48.9 35.0 0.304 0.0 GTX
GTX
HOH
 9.603
7.210
2.781
 CB
C
O
 O12
N1
O
ALA B:100 B:100 34.0 0.296 H -63.4 -42.4 34.0 0.296 0.0 GTX
GTX
HOH
 7.299
9.574
3.065
 C
CB
O
 N1
O12
O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 ALA A:100 A:100 32.0 0.278 H -69.3 -35.0 32.0 0.278 0.0 HOH
 2.388
 O
 O
ALA B:100 B:100 31.0 0.27 H -64.3 -27.6 31.0 0.27 0.0 HOH
 2.872
 O
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 ALA A:99 A:100 32.0 0.278 H -61.0 -41.1 32.0 0.278 0.0 GSH
BME
BME
GSH
HOH
 9.567
3.947
3.817
7.300
2.910
 CB
N
CB
C
O
 O12
S2
C2
N1
O
ALA B:99 B:100 34.0 0.296 H -63.3 -37.2 34.0 0.296 0.0 GSH
GSH
BME
BME
HOH
 7.191
9.563
3.880
3.735
3.044
 C
CB
N
CB
O
 N1
O11
S2
C2
O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 ALA A:99 A:100 32.0 0.278 H -68.3 -26.2 32.0 0.278 0.0 HOH
 3.964
 CB
 O
ALA B:99 B:100 31.0 0.27 H -68.2 -26.3 31.0 0.27 0.0 HOH
 3.964
 CB
 O
ALA C:99 C:100 32.0 0.278 H -68.3 -26.3 NA NA NA
ALA D:99 D:100 31.0 0.27 H -68.2 -26.3 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 ALA A:99 A:100 37.0 0.322 H -64.7 -28.5 37.0 0.322 0.0 HOH
 3.652
 O
 O
ALA B:99 B:100 35.0 0.304 H -64.7 -28.5 35.0 0.304 0.0 HOH
 3.652
 O
 O
ALA C:99 C:100 35.0 0.304 H -64.7 -28.5 NA NA NA
ALA D:99 D:100 36.0 0.313 H -64.7 -28.5 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 ALA A:99 A:100 33.0 0.287 H -68.4 -26.2 33.0 0.287 0.0 GSB
GSB
 9.509
7.281
 CB
C
 O12
N1
ALA B:99 B:100 33.0 0.287 H -68.4 -26.1 33.0 0.287 0.0 GSB
GSB
 7.260
9.509
 C
CB
 N1
O12
ALA C:99 C:100 33.0 0.287 H -68.4 -26.2 NA NA NA
ALA D:99 D:100 33.0 0.287 H -68.4 -26.2 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 ALA A:99 A:100 30.0 0.261 H -59.5 -40.2 30.0 0.261 0.0 GTX
GTX
HOH
 9.502
7.199
3.006
 CB
C
O
 O12
N1
O
ALA B:99 B:100 30.0 0.261 H -60.2 -41.7 30.0 0.261 0.0 GTX
GTX
HOH
 7.270
9.488
3.298
 C
CB
O
 N1
O12
O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 ALA A:99 A:100 36.0 0.313 H -71.8 -27.1 36.0 0.313 0.0 HOH
 3.779
 CB
 O
ALA B:99 B:100 37.0 0.322 H -70.6 -26.0 37.0 0.322 0.0 HOH
 3.671
 CB
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 ALA A:99 A:100 30.0 0.261 H -60.3 -43.0 30.0 0.261 0.0 GTX
GOL
GOL
GTX
GOL
HOH
 9.529
3.542
5.609
7.262
6.594
3.669
 CB
CB
CB
C
CB
CA
 O11
C3
O1
N1
O2
O
ALA B:99 B:100 29.0 0.252 H -61.8 -43.0 29.0 0.252 0.0 GTX
GOL
GTX
GOL
HOH
 7.222
6.764
9.567
5.575
3.606
 C
CB
CB
CB
O
 N1
O2
O12
O3
O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ALA A:99 A:100 31.0 0.27 H -64.6 -38.9 31.0 0.27 0.0 GSH
HOH
 9.175
3.841
 CB
N
 O12
O
ALA B:99 B:100 32.0 0.278 H -65.9 -39.1 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ALA A:99 A:100 29.0 0.252 H -66.8 -35.2 29.0 0.252 0.0 HOH
 2.889
 O
 O
ALA B:99 B:100 31.0 0.27 H -66.2 -35.3 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ALA A:99 A:100 31.0 0.27 H -64.5 -38.1 31.0 0.27 0.0 HOH
 3.760
 CB
 O
ALA B:99 B:100 30.0 0.261 H -67.2 -41.9 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ALA A:99 A:100 32.0 0.278 H -65.8 -36.2 32.0 0.278 0.0 BWS
GSN
EDO
EDO
EDO
HOH
 9.548
9.543
3.199
3.678
8.478
3.434
 CB
CB
CB
O
O
O
 OXT
OXT
H12
HO2
HO2
O
ALA B:99 B:100 33.0 0.287 H -66.0 -36.8 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 ALA A:100 A:100 31.0 0.27 H -63.2 -38.7 31.0 0.27 0.0 HOH
 3.222
 CB
 O
ALA B:100 B:100 29.0 0.252 H -64.3 -37.2 29.0 0.252 0.0 HOH
 2.644
 O
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 ALA A:100 A:100 32.0 0.278 H -63.7 -33.4 32.0 0.278 0.0 GTX
GTX
HOH
 9.147
7.176
2.892
 CB
C
O
 O12
N1
O
ALA B:100 B:100 29.0 0.252 H -61.1 -41.5 29.0 0.252 0.0 GTX
GTX
HOH
 7.165
9.327
2.818
 C
CB
O
 N1
O12
O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 ALA A:100 A:100 29.0 0.252 H -53.5 -44.1 29.0 0.252 0.0 HOH
 2.482
 O
 O
ALA B:100 B:100 33.0 0.287 H -60.9 -31.0 33.0 0.287 0.0 HOH
 3.506
 CB
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 ALA A:100 A:100 33.0 0.287 H -67.0 -38.4 33.0 0.287 0.0 ABY
HOH
 7.201
3.847
 C
N
 N1
O
ALA B:100 B:100 31.0 0.27 H -64.7 -36.6 31.0 0.27 0.0 ABY
HOH
 7.253
2.915
 C
O
 N1
O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 ALA A:100 A:100 31.0 0.27 H -67.6 -38.5 31.0 0.27 0.0 GTX
GTX
HOH
 9.485
7.411
3.582
 CB
C
CA
 O12
N1
O
ALA B:100 B:100 30.0 0.261 H -47.6 -41.1 30.0 0.261 0.0 GTX
GTX
HOH
 7.490
9.733
3.704
 C
CB
N
 N1
O12
O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 ALA A:99 A:100 31.0 0.27 H -67.3 -38.7 31.0 0.27 0.0 HOH
 2.885
 O
 O
ALA B:99 B:100 33.0 0.287 H -60.0 -37.5 33.0 0.287 0.0 HOH
 2.671
 O
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 ALA A:99 A:100 32.0 0.278 H -73.8 -37.7 32.0 0.278 0.0 GTX
GTX
HOH
 9.359
7.193
2.784
 CB
C
O
 O12
N1
O
ALA B:99 B:100 31.0 0.27 H -59.2 -39.7 31.0 0.27 0.0 GTX
GTX
HOH
 7.304
9.307
3.140
 C
CB
O
 N1
O12
O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 ALA A:103 A:100 20.0 0.174 H -59.5 -37.5 20.0 0.174 0.0 GSH
CL
GSH
HOH
 9.520
8.674
7.082
4.208
 CB
CB
C
O
 O12
CL
N1
O
ALA B:103 B:100 24.0 0.209 H -55.9 -46.5 24.0 0.209 0.0 GSH
GSH
CL
HOH
 7.266
9.658
8.549
3.518
 C
CB
CB
CB
 N1
O12
CL
O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 ALA A:99 A:100 32.0 0.278 H -66.4 -35.6 32.0 0.278 0.0 HOH
 3.752
 CB
 O
ALA B:99 B:100 31.0 0.27 H -59.7 -40.6 31.0 0.27 0.0 HOH
 3.683
 CB
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 ALA A:100 A:100 33.0 0.287 H -78.1 -27.2 33.0 0.287 0.0 HOH
 3.486
 O
 O
ALA B:100 B:100 33.0 0.287 H -59.4 -30.7 33.0 0.287 0.0 HOH
 3.261
 CB
 O
ALA C:100 C:100 36.0 0.313 H -63.0 -26.3 NA NA NA
ALA D:100 D:100 38.0 0.33 H -70.4 -25.8 NA NA NA
ALA E:100 E:100 37.0 0.322 H -72.2 -26.0 NA NA NA
ALA F:100 F:100 33.0 0.287 H -69.9 -34.0 NA NA NA
ALA G:100 G:100 30.0 0.261 H -65.4 -31.2 NA NA NA
ALA H:100 H:100 37.0 0.322 H -70.7 -26.3 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 ALA A:100 A:100 34.0 0.296 H -71.9 -22.8 34.0 0.296 0.0 GSH
HOH
 7.482
2.701
 C
O
 N1
O
ALA B:100 B:100 30.0 0.261 H -66.6 -33.0 30.0 0.261 0.0 GSH
GSH
HOH
 7.714
9.618
2.712
 C
CB
O
 N1
O11
O
ALA C:100 C:100 34.0 0.296 H -68.6 -25.8 NA NA NA
ALA D:100 D:100 30.0 0.261 H -64.3 -33.0 NA NA NA
ALA E:100 E:100 27.0 0.235 H -67.3 -31.3 NA NA NA
ALA F:100 F:100 36.0 0.313 H -72.2 -21.9 NA NA NA
ALA G:100 G:100 33.0 0.287 H -70.2 -33.6 NA NA NA
ALA H:100 H:100 31.0 0.27 H -70.3 -35.4 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 ALA A:99 A:100 29.0 0.252 H -58.7 -44.1 29.0 0.252 0.0 GVX
EDO
EDO
GVX
HOH
 9.451
3.686
3.840
7.190
3.920
 CB
O
N
C
CB
 O01
O1
O2
N05
O
ALA B:99 B:100 29.0 0.252 H -65.5 -41.2 29.0 0.252 0.0 GVX
GVX
HOH
 7.187
9.452
3.903
 C
CB
O
 N05
O01
O
ALA C:99 C:100 30.0 0.261 H -66.2 -37.5 NA NA NA
ALA D:99 D:100 30.0 0.261 H -56.5 -41.8 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 ALA A:97 A:100 32.0 0.278 H -67.7 -35.1 32.0 0.278 0.0 LZ6
LZ6
HOH
 9.483
7.156
3.448
 CB
C
O
 O36
N38
O
ALA B:97 B:100 31.0 0.27 H -58.6 -38.5 31.0 0.27 0.0 LZ6
LZ6
HOH
 7.124
9.398
2.670
 C
CB
O
 N38
O36
O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 ALA A:100 A:100 31.0 0.27 H -57.6 -31.1 31.0 0.27 0.0 GSH
GSH
HOH
 9.341
7.689
3.178
 CB
C
O
 O11
N1
O
ALA B:100 B:100 28.0 0.243 H -71.0 -36.8 28.0 0.243 0.0 GSH
HOH
 6.981
4.297
 C
O
 N1
O
ALA C:100 C:100 32.0 0.278 H -57.3 -41.5 NA NA NA
ALA D:100 D:100 30.0 0.261 H -62.4 -35.0 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 ALA A:100 A:100 33.0 0.287 H -62.0 -39.2 33.0 0.287 0.0 GSH
GSH
HOH
 9.518
7.317
2.980
 CB
C
O
 O12
N1
O
ALA B:100 B:100 26.0 0.226 H -63.4 -36.2 26.0 0.226 0.0 GSH
GSH
HOH
 7.276
9.346
3.112
 C
CB
O
 N1
O12
O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 ALA A:100 A:100 19.0 0.165 H -60.6 -38.1 19.0 0.165 0.0 GSH
GSH
HOH
 9.536
7.247
3.261
 CB
C
O
 O11
N1
O
ALA B:100 B:100 30.0 0.261 H -66.2 -32.4 30.0 0.261 0.0 GSH
GSH
HOH
 7.174
9.355
2.934
 C
CB
O
 N1
O11
O
ALA C:100 C:100 24.0 0.209 H -67.9 -31.1 NA NA NA
ALA D:100 D:100 21.0 0.183 H -64.1 -27.9 NA NA NA
ALA E:100 E:100 22.0 0.191 H -66.0 -34.6 NA NA NA
ALA F:100 F:100 28.0 0.243 H -65.9 -34.4 NA NA NA
ALA G:100 G:100 25.0 0.217 H -60.1 -32.0 NA NA NA
ALA H:100 H:100 25.0 0.217 H -68.8 -36.1 NA NA NA
ALA I:100 I:100 22.0 0.191 H -59.2 -39.6 NA NA NA
ALA J:100 J:100 19.0 0.165 H -59.7 -33.9 NA NA NA
ALA K:100 K:100 29.0 0.252 H -65.2 -31.2 NA NA NA
ALA L:100 L:100 27.0 0.235 H -63.8 -38.1 NA NA NA
ALA M:100 M:100 19.0 0.165 H -61.3 -35.5 NA NA NA
ALA N:100 N:100 20.0 0.174 H -69.5 -32.6 NA NA NA
ALA O:100 O:100 28.0 0.243 H -55.1 -37.6 NA NA NA
ALA P:100 P:100 26.0 0.226 H -66.6 -32.4 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 ALA A:100 A:100 32.0 0.278 H -72.1 -30.3 32.0 0.278 0.0 GSH
HOH
 7.552
5.020
 C
CB
 N1
O
ALA B:100 B:100 28.0 0.243 H -58.8 -42.4 28.0 0.243 0.0 GSH
HOH
 9.190
4.335
 CB
CB
 O12
O
ALA C:100 C:100 38.0 0.33 H -79.3 -28.4 NA NA NA
ALA D:100 D:100 30.0 0.261 H -65.3 -41.4 NA NA NA
ALA E:100 E:100 30.0 0.261 H -63.6 -34.6 NA NA NA
ALA F:100 F:100 32.0 0.278 H -59.8 -38.8 NA NA NA
ALA G:100 G:100 32.0 0.278 H -63.7 -37.0 NA NA NA
ALA H:100 H:100 30.0 0.261 H -64.0 -39.2 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 ALA A:100 A:100 31.0 0.27 H -53.9 -40.6 31.0 0.27 0.0 GSH
GSH
HOH
 9.088
7.210
4.644
 CB
C
CB
 O11
N1
O
ALA B:100 B:100 29.0 0.252 H -70.7 -38.9 29.0 0.252 0.0 GSH
GSH
HOH
 6.956
8.965
3.974
 C
CB
CB
 N1
O12
O
ALA C:100 C:100 30.0 0.261 H -62.1 -43.5 NA NA NA
ALA D:100 D:100 30.0 0.261 H -68.3 -40.3 NA NA NA
ALA E:100 E:100 30.0 0.261 H -56.6 -42.7 NA NA NA
ALA F:100 F:100 27.0 0.235 H -57.2 -41.3 NA NA NA
ALA G:100 G:100 30.0 0.261 H -62.1 -34.7 NA NA NA
ALA H:100 H:100 29.0 0.252 H -68.1 -40.0 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 ALA A:100 A:100 30.0 0.261 H -63.6 -35.0 30.0 0.261 0.0 BOB
BOB
HOH
 8.848
7.274
7.871
 CB
C
CB
 O11
N1
O
ALA B:100 B:100 28.0 0.243 H -56.4 -40.0 28.0 0.243 0.0 BOB
BOB
HOH
 6.988
8.978
6.682
 C
CB
O
 N1
O11
O
ALA C:100 C:100 32.0 0.278 H -66.0 -31.3 NA NA NA
ALA D:100 D:100 29.0 0.252 H -55.4 -42.9 NA NA NA
ALA E:100 E:100 32.0 0.278 H -66.4 -28.7 NA NA NA
ALA F:100 F:100 29.0 0.252 H -56.7 -35.6 NA NA NA
ALA G:100 G:100 30.0 0.261 H -53.6 -35.7 NA NA NA
ALA H:100 H:100 32.0 0.278 H -53.2 -35.6 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 LEU A:100 A:100 34.0 0.2 H -66.3 -35.9 34.0 0.2 0.0 GSH
HOH
 7.851
3.075
 CD2
CD2
 O12
O
LEU B:100 B:100 37.0 0.218 H -60.3 -41.1 37.0 0.218 0.0 GSH
HOH
 7.406
4.930
 C
CD2
 N1
O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 LEU A:100 A:100 29.0 0.171 H -63.0 -36.9 29.0 0.171 0.0 CL
CL
HOH
 7.636
7.224
3.070
 CD1
CD1
CD1
 CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 VAL A:100 A:100 29.0 0.187 H -62.2 -46.5
af-p08263-f1 1 P08263 90.09 6e-146 ALA A:100 A:100 34.0 0.296 H -63.3 -42.0
af-p09210-f1 1 P09210 88.74 1e-143 ALA A:100 A:100 33.0 0.287 H -63.5 -39.8
af-q16772-f1 1 Q16772 85.59 7e-139 ALA A:100 A:100 29.0 0.252 H -62.1 -39.0