Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52701085 . T A CCDS4946.1:NM_153699.1:c.221tAc>tTc_NP_714543.1:p.74Y>F Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 TYR A:74 A:74 74.0 0.322 H -65.3 -52.0 10.0 0.043 0.279 B:P08263:0.278
 HOH
 2.709
 OH
 O
TYR B:74 B:74 74.0 0.322 H -64.7 -49.0 9.0 0.039 0.283 A:P08263:0.283
 HOH
 2.665
 OH
 O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 TYR A:74 A:74 72.0 0.313 H -64.0 -53.2 10.0 0.043 0.27 B:P08263:0.27
 HOH
 3.278
 N
 O
TYR B:74 B:74 76.0 0.33 H -63.1 -49.4 8.0 0.035 0.295 A:P08263:0.296
 HED
HOH
 9.886
3.261
 N
CA
 O6
O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 TYR A:74 A:74 71.0 0.309 H -67.8 -52.2 10.0 0.043 0.266 B:P08263:0.265
 HOH
 2.862
 OH
 O
TYR B:74 B:74 73.0 0.317 H -64.9 -50.9 11.0 0.048 0.269 A:P08263:0.27
 HOH
 2.553
 OH
 O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 TYR A:74 A:74 74.0 0.322 H -62.9 -46.6 8.0 0.035 0.287 B:P08263:0.287
 HOH
 3.392
 N
 O
TYR B:74 B:74 73.0 0.317 H -68.9 -47.4 4.0 0.017 0.3 A:P08263:0.3
 HOH
 3.250
 CA
 O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 TYR A:74 A:74 69.0 0.3 H -53.4 -58.5 8.0 0.035 0.265 B:P08263:0.265
 HOH
 3.400
 CA
 O
TYR B:74 B:74 71.0 0.309 H -55.7 -56.5 7.0 0.03 0.279 A:P08263:0.278
 HOH
 6.913
 N
 O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 TYR A:74 A:74 79.0 0.343 H -61.0 -52.2 9.0 0.039 0.304 B:P08263:0.304
 HOH
 3.366
 CA
 O
TYR B:74 B:74 78.0 0.339 H -62.1 -51.4 7.0 0.03 0.309 A:P08263:0.309
 HOH
 3.242
 CA
 O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 TYR A:74 A:74 74.0 0.322 H -66.2 -47.1 8.0 0.035 0.287 B:P08263:0.287
 HOH
 2.986
 OH
 O
TYR B:74 B:74 74.0 0.322 H -65.3 -47.6 8.0 0.035 0.287 A:P08263:0.287
 HOH
 5.455
 CE1
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 TYR A:73 A:74 75.0 0.326 H -61.5 -54.6 10.0 0.043 0.283 B:P08263:0.283
 BME
HOH
 9.882
3.231
 N
OH
 O1
O
TYR B:73 B:74 73.0 0.317 H -62.5 -51.7 8.0 0.035 0.282 A:P08263:0.283
 BME
HOH
 9.647
3.411
 N
CA
 O1
O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 TYR A:73 A:74 74.0 0.322 H -60.2 -54.9 9.0 0.039 0.283 B:P08263:0.283
 HOH
 3.391
 CA
 O
TYR B:73 B:74 73.0 0.317 H -60.2 -54.9 9.0 0.039 0.278 A:P08263:0.278
 HOH
 3.339
 CA
 O
TYR C:73 C:74 75.0 0.326 H -60.2 -55.0 NA NA NA
TYR D:73 D:74 76.0 0.33 H -60.2 -55.0 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 TYR A:73 A:74 74.0 0.322 H -63.8 -55.6 10.0 0.043 0.279 B:P08263:0.278
 HOH
 3.427
 CA
 O
TYR B:73 B:74 73.0 0.317 H -63.8 -55.5 10.0 0.043 0.274 A:P08263:0.274
 HOH
 3.360
 CA
 O
TYR C:73 C:74 73.0 0.317 H -63.7 -55.6 NA NA NA
TYR D:73 D:74 72.0 0.313 H -63.8 -55.5 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 TYR A:73 A:74 78.0 0.339 H -70.4 -54.5 11.0 0.048 0.291 B:P08263:0.291
TYR B:73 B:74 77.0 0.335 H -70.4 -54.5 11.0 0.048 0.287 A:P08263:0.287
TYR C:73 C:74 78.0 0.339 H -70.4 -54.5 NA NA NA
TYR D:73 D:74 78.0 0.339 H -70.4 -54.4 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 TYR A:73 A:74 74.0 0.322 H -65.2 -51.0 10.0 0.043 0.279 B:P08263:0.278
 HOH
 3.318
 CA
 O
TYR B:73 B:74 73.0 0.317 H -61.6 -50.7 11.0 0.048 0.269 A:P08263:0.27
 HOH
 3.306
 CA
 O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 TYR A:73 A:74 75.0 0.326 H -60.7 -51.6 11.0 0.048 0.278 B:P08263:0.278
 HOH
 3.466
 N
 O
TYR B:73 B:74 75.0 0.326 H -67.0 -50.0 11.0 0.048 0.278 A:P08263:0.278
 HOH
 3.122
 CA
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 TYR A:73 A:74 75.0 0.326 H -61.8 -53.0 8.0 0.035 0.291 B:P08263:0.291
 HOH
 2.869
 OH
 O
TYR B:73 B:74 81.0 0.352 H -61.3 -49.5 11.0 0.048 0.304 A:P08263:0.304
 HOH
 3.339
 CA
 O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 TYR A:73 A:74 80.0 0.348 H -66.8 -49.5 80.0 0.348 0.0 MPD
HOH
 9.050
3.215
 OH
OH
 HO4
O
TYR B:73 B:74 76.0 0.33 H -65.3 -49.5 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 TYR A:73 A:74 75.0 0.326 H -66.7 -49.2 75.0 0.326 0.0 MPD
HOH
 8.623
3.267
 CE1
OH
 H52
O
TYR B:73 B:74 77.0 0.335 H -62.8 -49.7 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 TYR A:73 A:74 74.0 0.322 H -62.4 -52.0 74.0 0.322 0.0 MPD
HOH
 8.559
2.939
 CE1
OH
 H52
O
TYR B:73 B:74 76.0 0.33 H -58.6 -53.5 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 TYR A:73 A:74 73.0 0.317 H -65.7 -48.8 73.0 0.317 0.0 EDO
EDO
EDO
HOH
 9.429
9.110
8.745
2.714
 CD1
N
CE2
OH
 H11
H22
HO2
O
TYR B:73 B:74 73.0 0.317 H -65.8 -48.7 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 TYR A:74 A:74 76.0 0.33 H -57.6 -52.7 7.0 0.03 0.3 B:P08263:0.3
 HOH
 2.747
 OH
 O
TYR B:74 B:74 73.0 0.317 H -57.8 -49.9 8.0 0.035 0.282 A:P08263:0.283
 HOH
 2.698
 OH
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 TYR A:74 A:74 73.0 0.317 H -65.6 -51.8 8.0 0.035 0.282 B:P08263:0.283
 HOH
 2.728
 OH
 O
TYR B:74 B:74 77.0 0.335 H -63.2 -49.4 10.0 0.043 0.292 A:P08263:0.291
 HOH
 2.415
 OH
 O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 TYR A:74 A:74 67.0 0.291 H -65.9 -46.0 7.0 0.03 0.261 B:P08263:0.261
 HOH
 3.310
 OH
 O
TYR B:74 B:74 74.0 0.322 H -59.1 -46.2 10.0 0.043 0.279 A:P08263:0.278
 HOH
 3.272
 CA
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 TYR A:74 A:74 70.0 0.304 H -68.0 -49.3 9.0 0.039 0.265 B:P08263:0.265
 HOH
 2.828
 OH
 O
TYR B:74 B:74 72.0 0.313 H -61.7 -51.2 10.0 0.043 0.27 A:P08263:0.27
 HOH
 2.634
 OH
 O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 TYR A:74 A:74 73.0 0.317 H -59.0 -44.5 10.0 0.043 0.274 B:P08263:0.274
 HOH
 3.111
 OH
 O
TYR B:74 B:74 79.0 0.343 H -69.5 -57.8 10.0 0.043 0.3 A:P08263:0.3
 HOH
 3.347
 CD1
 O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 TYR A:73 A:74 75.0 0.326 H -61.4 -53.0 9.0 0.039 0.287 B:P08263:0.287
 HOH
 3.328
 CA
 O
TYR B:73 B:74 75.0 0.326 H -66.4 -52.7 7.0 0.03 0.296 A:P08263:0.296
 HOH
 3.248
 OH
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 TYR A:73 A:74 72.0 0.313 H -65.5 -53.4 9.0 0.039 0.274 B:P08263:0.274
 HOH
 3.020
 OH
 O
TYR B:73 B:74 74.0 0.322 H -71.8 -51.5 9.0 0.039 0.283 A:P08263:0.283
 HOH
 2.740
 OH
 O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 TYR A:77 A:74 74.0 0.322 H -61.2 -54.6 8.0 0.035 0.287 B:P08263:0.287
 CL
HOH
 8.865
3.420
 N
N
 CL
O
TYR B:77 B:74 73.0 0.317 H -63.6 -48.1 8.0 0.035 0.282 A:P08263:0.283
 CL
HOH
 9.001
2.742
 N
OH
 CL
O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 TYR A:73 A:74 74.0 0.322 H -68.0 -51.2 10.0 0.043 0.279 B:P08263:0.278
 HOH
 2.870
 OH
 O
TYR B:73 B:74 74.0 0.322 H -61.1 -51.0 10.0 0.043 0.279 A:P08263:0.278
 HOH
 2.646
 OH
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 TYR A:74 A:74 74.0 0.322 H -53.7 -53.7 7.0 0.03 0.292 B:P09210:0.291
 HOH
 2.720
 OH
 O
TYR B:74 B:74 69.0 0.3 H -62.1 -52.1 9.0 0.039 0.261 A:P09210:0.261
 HOH
 2.890
 OH
 O
TYR C:74 C:74 71.0 0.309 H -60.3 -48.8 NA NA NA
TYR D:74 D:74 73.0 0.317 H -64.8 -53.3 NA NA NA
TYR E:74 E:74 71.0 0.309 H -69.7 -51.6 NA NA NA
TYR F:74 F:74 70.0 0.304 H -58.5 -52.9 NA NA NA
TYR G:74 G:74 78.0 0.339 H -73.3 -46.0 NA NA NA
TYR H:74 H:74 75.0 0.326 H -61.5 -47.4 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 TYR A:74 A:74 76.0 0.33 H -58.5 -49.4 12.0 0.052 0.278 B:P09210:0.278
 HOH
 3.552
 CA
 O
TYR B:74 B:74 72.0 0.313 H -49.7 -50.7 8.0 0.035 0.278 A:P09210:0.278
 HOH
 3.183
 N
 O
TYR C:74 C:74 76.0 0.33 H -57.7 -51.5 NA NA NA
TYR D:74 D:74 75.0 0.326 H -64.8 -31.8 NA NA NA
TYR E:74 E:74 72.0 0.313 H -60.1 -43.8 NA NA NA
TYR F:74 F:74 73.0 0.317 H -63.0 -61.7 NA NA NA
TYR G:74 G:74 67.0 0.291 H -61.0 -53.9 NA NA NA
TYR H:74 H:74 70.0 0.304 H -57.2 -57.2 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 TYR A:73 A:74 73.0 0.317 H -64.4 -49.7 8.0 0.035 0.282 B:P08263:0.283
 HOH
 3.020
 OH
 O
TYR B:73 B:74 73.0 0.317 H -67.6 -48.3 5.0 0.022 0.295 A:P08263:0.296
 HOH
 3.307
 CA
 O
TYR C:73 C:74 75.0 0.326 H -67.4 -49.1 NA NA NA
TYR D:73 D:74 73.0 0.317 H -65.1 -52.4 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 TYR A:71 A:74 81.0 0.352 H -64.8 -50.9 5.0 0.022 0.33 B:P08263:0.33
 HOH
 3.301
 CA
 O
TYR B:71 B:74 80.0 0.348 H -62.0 -54.2 8.0 0.035 0.313 A:P08263:0.313
 HOH
 3.337
 CA
 O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 TYR A:74 A:74 76.0 0.33 H -60.1 -50.5 12.0 0.052 0.278 B:P09210:0.278
 HOH
 4.886
 N
 O
TYR B:74 B:74 69.0 0.3 H -64.6 -55.1 10.0 0.043 0.257 A:P09210:0.257
 HOH
 3.720
 OH
 O
TYR C:74 C:74 78.0 0.339 H -66.7 -41.8 NA NA NA
TYR D:74 D:74 77.0 0.335 H -57.2 -50.3 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 TYR A:74 A:74 75.0 0.326 H -58.3 -46.5 10.0 0.043 0.283 B:Q16772:0.283
 HOH
 3.395
 CA
 O
TYR B:74 B:74 77.0 0.335 H -63.1 -48.0 10.0 0.043 0.292 A:Q16772:0.291
 HOH
 2.969
 OH
 O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 TYR A:74 A:74 74.0 0.322 H -62.7 -48.6 8.0 0.035 0.287 B:Q16772:0.287
 HOH
 2.726
 OH
 O
TYR B:74 B:74 74.0 0.322 H -59.9 -54.9 13.0 0.057 0.265 A:Q16772:0.265
 HOH
 3.259
 CA
 O
TYR C:74 C:74 71.0 0.309 H -65.0 -46.5 NA NA NA
TYR D:74 D:74 68.0 0.296 H -59.7 -53.0 NA NA NA
TYR E:74 E:74 74.0 0.322 H -55.6 -50.9 NA NA NA
TYR F:74 F:74 74.0 0.322 H -62.7 -47.0 NA NA NA
TYR G:74 G:74 73.0 0.317 H -65.7 -53.0 NA NA NA
TYR H:74 H:74 76.0 0.33 H -60.3 -45.7 NA NA NA
TYR I:74 I:74 75.0 0.326 H -63.1 -47.1 NA NA NA
TYR J:74 J:74 70.0 0.304 H -63.7 -51.5 NA NA NA
TYR K:74 K:74 73.0 0.317 H -64.2 -53.8 NA NA NA
TYR L:74 L:74 71.0 0.309 H -57.6 -49.9 NA NA NA
TYR M:74 M:74 75.0 0.326 H -61.8 -50.6 NA NA NA
TYR N:74 N:74 71.0 0.309 H -60.0 -49.4 NA NA NA
TYR O:74 O:74 76.0 0.33 H -65.4 -48.3 NA NA NA
TYR P:74 P:74 73.0 0.317 H -62.5 -47.3 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 TYR A:74 A:74 70.0 0.304 H -60.7 -44.2 8.0 0.035 0.269 B:P08263:0.27
 HOH
 3.383
 N
 O
TYR B:74 B:74 69.0 0.3 H -57.6 -50.5 8.0 0.035 0.265 A:P08263:0.265
 HOH
 3.519
 CA
 O
TYR C:74 C:74 73.0 0.317 H -55.3 -56.7 NA NA NA
TYR D:74 D:74 75.0 0.326 H -55.1 -51.8 NA NA NA
TYR E:74 E:74 78.0 0.339 H -64.0 -37.5 NA NA NA
TYR F:74 F:74 71.0 0.309 H -68.7 -55.0 NA NA NA
TYR G:74 G:74 77.0 0.335 H -58.6 -44.9 NA NA NA
TYR H:74 H:74 70.0 0.304 H -63.4 -42.7 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 TYR A:74 A:74 71.0 0.309 H -64.1 -47.8 8.0 0.035 0.274 B:P08263:0.274
 HOH
 3.339
 N
 O
TYR B:74 B:74 70.0 0.304 H -57.2 -50.4 9.0 0.039 0.265 A:P08263:0.265
 HOH
 3.342
 CA
 O
TYR C:74 C:74 71.0 0.309 H -69.4 -46.2 NA NA NA
TYR D:74 D:74 74.0 0.322 H -62.9 -57.4 NA NA NA
TYR E:74 E:74 77.0 0.335 H -62.8 -44.1 NA NA NA
TYR F:74 F:74 75.0 0.326 H -62.1 -54.6 NA NA NA
TYR G:74 G:74 75.0 0.326 H -61.8 -49.8 NA NA NA
TYR H:74 H:74 75.0 0.326 H -61.3 -48.0 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 TYR A:74 A:74 75.0 0.326 H -59.9 -48.2 10.0 0.043 0.283 B:P08263:0.283
 HOH
 9.027
 N
 O
TYR B:74 B:74 72.0 0.313 H -64.4 -46.7 8.0 0.035 0.278 A:P08263:0.278
 HOH
 9.206
 N
 O
TYR C:74 C:74 66.0 0.287 H -71.3 -41.2 NA NA NA
TYR D:74 D:74 73.0 0.317 H -61.2 -48.6 NA NA NA
TYR E:74 E:74 77.0 0.335 H -65.7 -51.5 NA NA NA
TYR F:74 F:74 80.0 0.348 H -59.6 -50.4 NA NA NA
TYR G:74 G:74 75.0 0.326 H -61.6 -41.9 NA NA NA
TYR H:74 H:74 72.0 0.313 H -58.9 -52.9 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 TYR A:74 A:74 77.0 0.335 H -62.3 -52.8 6.0 0.026 0.309 B:P08263+P04903:0.309
 HOH
 3.372
 N
 O
TYR B:74 B:74 78.0 0.339 H -65.5 -52.0 13.0 0.057 0.282 A:P08263+P04903:0.283
 HOH
 3.351
 CA
 O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 TYR A:74 A:74 74.0 0.322 H -67.8 -46.6 13.0 0.057 0.265 A:P08263+P04903:0.265
 CL
CL
HOH
 8.485
8.148
2.688
 N
N
OH
 CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 TYR A:74 A:74 77.0 0.335 H -63.8 -50.6
af-p08263-f1 1 P08263 90.09 6e-146 TYR A:74 A:74 71.0 0.309 H -62.6 -52.7
af-p09210-f1 1 P09210 88.74 1e-143 TYR A:74 A:74 73.0 0.317 H -62.5 -52.9
af-q16772-f1 1 Q16772 85.59 7e-139 TYR A:74 A:74 73.0 0.317 H -62.4 -52.1