Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52701087 . G A CCDS4946.1:NM_153699.1:c.219aaC>aaT_NP_714543.1:p.73N>N Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ASN A:73 A:73 61.0 0.381 H -64.0 -41.9 10.0 0.062 0.319 B:P08263:0.319
 HED
HED
HOH
 6.046
8.724
2.697
 OD1
ND2
OD1
 C2
C5
O
ASN B:73 B:73 45.0 0.281 H -60.0 -40.9 12.0 0.075 0.206 A:P08263:0.206
 HED
HED
HOH
 8.685
6.199
2.784
 ND2
OD1
OD1
 C2
C5
O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ASN A:73 A:73 61.0 0.381 H -55.4 -44.7 12.0 0.075 0.306 B:P08263:0.306
 HED
HED
HOH
 6.047
7.954
2.846
 OD1
ND2
ND2
 C2
O6
O
ASN B:73 B:73 48.0 0.3 H -59.8 -43.7 12.0 0.075 0.225 A:P08263:0.225
 HED
HED
HOH
 8.689
5.659
2.860
 ND2
OD1
OD1
 C2
O6
O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 ASN A:73 A:73 61.0 0.381 H -59.8 -41.8 15.0 0.094 0.287 B:P08263:0.287
 HOH
 2.730
 OD1
 O
ASN B:73 B:73 59.0 0.369 H -60.3 -42.3 13.0 0.081 0.288 A:P08263:0.287
 HOH
 2.718
 OD1
 O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 ASN A:73 A:73 61.0 0.381 H -61.6 -43.8 10.0 0.062 0.319 B:P08263:0.319
 HOH
 2.663
 OD1
 O
ASN B:73 B:73 45.0 0.281 H -56.9 -41.4 12.0 0.075 0.206 A:P08263:0.206
 HOH
 2.828
 ND2
 O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 ASN A:73 A:73 41.0 0.256 H -63.6 -47.8 9.0 0.056 0.2 B:P08263:0.2
 HOH
 4.140
 C
 O
ASN B:73 B:73 55.0 0.344 H -58.7 -47.4 5.0 0.031 0.313 A:P08263:0.312
 HOH
 2.644
 OD1
 O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 ASN A:73 A:73 60.0 0.375 H -56.8 -45.4 14.0 0.087 0.288 B:P08263:0.287
 HOH
 2.873
 OD1
 O
ASN B:73 B:73 60.0 0.375 H -58.0 -43.2 13.0 0.081 0.294 A:P08263:0.294
 HOH
 2.697
 OD1
 O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 ASN A:73 A:73 44.0 0.275 H -57.4 -41.0 8.0 0.05 0.225 B:P08263:0.225
 HOH
 2.676
 OD1
 O
ASN B:73 B:73 46.0 0.287 H -56.3 -46.2 10.0 0.062 0.225 A:P08263:0.225
 HOH
 2.942
 OD1
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 ASN A:72 A:73 47.0 0.294 H -65.2 -41.1 11.0 0.069 0.225 B:P08263:0.225
 BME
BME
BME
HOH
 8.739
5.351
6.917
2.797
 OD1
OD1
ND2
OD1
 S2
O1
O1
O
ASN B:72 B:73 45.0 0.281 H -61.8 -42.5 9.0 0.056 0.225 A:P08263:0.225
 BME
BME
BME
HOH
 7.203
8.745
5.068
2.895
 ND2
OD1
OD1
OD1
 O1
S2
O1
O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 ASN A:72 A:73 47.0 0.294 H -66.4 -44.1 8.0 0.05 0.244 B:P08263:0.244
 HOH
 2.843
 ND2
 O
ASN B:72 B:73 45.0 0.281 H -66.5 -44.1 10.0 0.062 0.219 A:P08263:0.219
 HOH
 2.984
 OD1
 O
ASN C:72 C:73 45.0 0.281 H -66.4 -44.2 NA NA NA
ASN D:72 D:73 47.0 0.294 H -66.4 -44.2 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 ASN A:72 A:73 59.0 0.369 H -69.5 -42.1 13.0 0.081 0.288 B:P08263:0.287
 HOH
 3.047
 OD1
 O
ASN B:72 B:73 60.0 0.375 H -69.6 -42.0 16.0 0.1 0.275 A:P08263:0.275
 HOH
 3.046
 OD1
 O
ASN C:72 C:73 60.0 0.375 H -69.5 -42.1 NA NA NA
ASN D:72 D:73 61.0 0.381 H -69.6 -42.1 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 ASN A:72 A:73 53.0 0.331 H -66.1 -33.9 8.0 0.05 0.281 B:P08263:0.281
ASN B:72 B:73 52.0 0.325 H -66.1 -33.9 8.0 0.05 0.275 A:P08263:0.275
ASN C:72 C:73 53.0 0.331 H -66.1 -33.9 NA NA NA
ASN D:72 D:73 51.0 0.319 H -66.1 -33.9 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 ASN A:72 A:73 47.0 0.294 H -60.8 -41.3 10.0 0.062 0.232 B:P08263:0.231
 HOH
 2.777
 OD1
 O
ASN B:72 B:73 45.0 0.281 H -64.1 -41.3 10.0 0.062 0.219 A:P08263:0.219
 HOH
 2.701
 OD1
 O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 ASN A:72 A:73 62.0 0.388 H -65.4 -37.8 15.0 0.094 0.294 B:P08263:0.294
 HOH
 2.790
 OD1
 O
ASN B:72 B:73 48.0 0.3 H -61.1 -36.9 18.0 0.113 0.187 A:P08263:0.188
 HOH
 2.893
 OD1
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 ASN A:72 A:73 60.0 0.375 H -60.4 -44.0 16.0 0.1 0.275 B:P08263:0.275
 GOL
HOH
 6.131
2.752
 OD1
OD1
 C2
O
ASN B:72 B:73 60.0 0.375 H -62.4 -41.9 16.0 0.1 0.275 A:P08263:0.275
 GOL
HOH
 8.240
2.723
 ND2
OD1
 O2
O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ASN A:72 A:73 62.0 0.388 H -60.4 -41.5 62.0 0.388 0.0 HOH
 2.827
 OD1
 O
ASN B:72 B:73 43.0 0.269 H -63.4 -39.7 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ASN A:72 A:73 62.0 0.388 H -57.6 -42.9 62.0 0.388 0.0 HOH
 2.825
 OD1
 O
ASN B:72 B:73 44.0 0.275 H -59.2 -43.1 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ASN A:72 A:73 60.0 0.375 H -57.9 -46.9 60.0 0.375 0.0 HOH
 2.908
 OD1
 O
ASN B:72 B:73 45.0 0.281 H -60.0 -45.6 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 ASN A:72 A:73 60.0 0.375 H -62.4 -40.9 60.0 0.375 0.0 EDO
HOH
 5.372
2.750
 OD1
OD1
 H22
O
ASN B:72 B:73 44.0 0.275 H -60.7 -40.9 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 ASN A:73 A:73 44.0 0.275 H -63.2 -43.5 9.0 0.056 0.219 B:P08263:0.219
 HOH
 2.692
 OD1
 O
ASN B:73 B:73 48.0 0.3 H -57.0 -45.6 11.0 0.069 0.231 A:P08263:0.231
 HOH
 2.840
 OD1
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 ASN A:73 A:73 62.0 0.388 H -60.7 -43.2 11.0 0.069 0.319 B:P08263:0.319
 HOH
 2.778
 O
 O
ASN B:73 B:73 44.0 0.275 H -60.1 -41.5 10.0 0.062 0.213 A:P08263:0.212
 HOH
 2.830
 OD1
 O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 ASN A:73 A:73 46.0 0.287 H -60.1 -42.6 13.0 0.081 0.206 B:P08263:0.206
 HOH
 2.718
 OD1
 O
ASN B:73 B:73 61.0 0.381 H -49.2 -50.1 10.0 0.062 0.319 A:P08263:0.319
 HOH
 2.789
 ND2
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 ASN A:73 A:73 61.0 0.381 H -58.9 -42.1 15.0 0.094 0.287 B:P08263:0.287
 HOH
 2.718
 OD1
 O
ASN B:73 B:73 59.0 0.369 H -63.2 -42.2 13.0 0.081 0.288 A:P08263:0.287
 HOH
 2.644
 OD1
 O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 ASN A:73 A:73 59.0 0.369 H -59.4 -42.1 10.0 0.062 0.307 B:P08263:0.306
 HOH
 2.821
 OD1
 O
ASN B:73 B:73 48.0 0.3 H -52.5 -45.0 13.0 0.081 0.219 A:P08263:0.219
 HOH
 3.009
 OD1
 O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 ASN A:72 A:73 45.0 0.281 H -60.9 -43.3 12.0 0.075 0.206 B:P08263:0.206
 HOH
 2.952
 OD1
 O
ASN B:72 B:73 61.0 0.381 H -52.6 -42.8 10.0 0.062 0.319 A:P08263:0.319
 HOH
 2.890
 OD1
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 ASN A:72 A:73 44.0 0.275 H -70.2 -38.2 13.0 0.081 0.194 B:P08263:0.194
 HOH
 2.853
 OD1
 O
ASN B:72 B:73 60.0 0.375 H -62.3 -40.1 9.0 0.056 0.319 A:P08263:0.319
 HOH
 2.898
 OD1
 O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 ASN A:76 A:73 59.0 0.369 H -53.5 -44.5 11.0 0.069 0.3 B:P08263:0.3
 CL
HOH
 6.477
2.703
 N
OD1
 CL
O
ASN B:76 B:73 46.0 0.287 H -61.9 -44.7 13.0 0.081 0.206 A:P08263:0.206
 CL
HOH
 6.625
2.789
 N
OD1
 CL
O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 ASN A:72 A:73 65.0 0.406 H -61.2 -42.7 12.0 0.075 0.331 B:P08263:0.331
 HOH
 2.838
 OD1
 O
ASN B:72 B:73 45.0 0.281 H -62.5 -42.2 13.0 0.081 0.2 A:P08263:0.2
 HOH
 2.867
 OD1
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 ASN A:73 A:73 55.0 0.344 H -66.6 -46.1 10.0 0.062 0.282 B:P09210:0.281
 HOH
 2.752
 OD1
 O
ASN B:73 B:73 56.0 0.35 H -59.2 -42.7 12.0 0.075 0.275 A:P09210:0.275
 HOH
 2.572
 OD1
 O
ASN C:73 C:73 55.0 0.344 H -67.0 -40.1 NA NA NA
ASN D:73 D:73 56.0 0.35 H -61.3 -41.4 NA NA NA
ASN E:73 E:73 60.0 0.375 H -56.3 -43.7 NA NA NA
ASN F:73 F:73 53.0 0.331 H -51.0 -50.0 NA NA NA
ASN G:73 G:73 59.0 0.369 H -50.1 -43.8 NA NA NA
ASN H:73 H:73 58.0 0.362 H -62.7 -44.2 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 ASN A:73 A:73 57.0 0.356 H -63.7 -41.5 15.0 0.094 0.262 B:P09210:0.263
 HOH
 2.600
 ND2
 O
ASN B:73 B:73 54.0 0.338 H -53.1 -56.4 11.0 0.069 0.269 A:P09210:0.269
 HOH
 2.709
 OD1
 O
ASN C:73 C:73 57.0 0.356 H -60.5 -47.4 NA NA NA
ASN D:73 D:73 53.0 0.331 H -58.4 -43.9 NA NA NA
ASN E:73 E:73 56.0 0.35 H -50.9 -47.7 NA NA NA
ASN F:73 F:73 62.0 0.388 H -59.1 -44.2 NA NA NA
ASN G:73 G:73 56.0 0.35 H -58.3 -42.9 NA NA NA
ASN H:73 H:73 61.0 0.381 H -71.8 -46.4 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 ASN A:72 A:73 48.0 0.3 H -56.9 -46.7 13.0 0.081 0.219 B:P08263:0.219
 EDO
HOH
 5.827
2.783
 OD1
OD1
 O1
O
ASN B:72 B:73 59.0 0.369 H -56.0 -45.2 9.0 0.056 0.313 A:P08263:0.312
 EDO
HOH
 8.252
2.708
 ND2
OD1
 O1
O
ASN C:72 C:73 60.0 0.375 H -57.7 -40.6 NA NA NA
ASN D:72 D:73 45.0 0.281 H -57.1 -43.6 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 ASN A:70 A:73 62.0 0.388 H -58.1 -41.5 9.0 0.056 0.332 B:P08263:0.331
 HOH
 2.730
 OD1
 O
ASN B:70 B:73 44.0 0.275 H -57.6 -45.6 13.0 0.081 0.194 A:P08263:0.194
 HOH
 2.854
 OD1
 O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 ASN A:73 A:73 60.0 0.375 H -48.6 -53.2 14.0 0.087 0.288 B:P09210:0.287
 HOH
 2.902
 OD1
 O
ASN B:73 B:73 57.0 0.356 H -55.2 -44.1 12.0 0.075 0.281 A:P09210:0.281
 HOH
 2.527
 OD1
 O
ASN C:73 C:73 60.0 0.375 H -47.5 -45.0 NA NA NA
ASN D:73 D:73 64.0 0.4 H -58.0 -49.2 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 ASN A:73 A:73 60.0 0.375 H -61.3 -44.3 17.0 0.106 0.269 B:Q16772:0.269
 HOH
 3.167
 ND2
 O
ASN B:73 B:73 59.0 0.369 H -62.4 -40.8 16.0 0.1 0.269 A:Q16772:0.269
 HOH
 3.087
 ND2
 O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 ASN A:73 A:73 61.0 0.381 H -63.4 -44.8 14.0 0.087 0.294 B:Q16772:0.294
 HOH
 2.944
 ND2
 O
ASN B:73 B:73 56.0 0.35 H -59.1 -45.1 13.0 0.081 0.269 A:Q16772:0.269
 HOH
 2.872
 OD1
 O
ASN C:73 C:73 58.0 0.362 H -51.5 -44.3 NA NA NA
ASN D:73 D:73 58.0 0.362 H -61.3 -44.1 NA NA NA
ASN E:73 E:73 57.0 0.356 H -57.4 -49.9 NA NA NA
ASN F:73 F:73 57.0 0.356 H -55.4 -46.8 NA NA NA
ASN G:73 G:73 59.0 0.369 H -59.6 -41.9 NA NA NA
ASN H:73 H:73 55.0 0.344 H -60.0 -42.9 NA NA NA
ASN I:73 I:73 58.0 0.362 H -55.7 -44.8 NA NA NA
ASN J:73 J:73 58.0 0.362 H -53.0 -44.2 NA NA NA
ASN K:73 K:73 58.0 0.362 H -65.1 -40.6 NA NA NA
ASN L:73 L:73 57.0 0.356 H -51.9 -47.2 NA NA NA
ASN M:73 M:73 60.0 0.375 H -54.6 -46.5 NA NA NA
ASN N:73 N:73 56.0 0.35 H -55.4 -44.7 NA NA NA
ASN O:73 O:73 58.0 0.362 H -60.6 -42.6 NA NA NA
ASN P:73 P:73 57.0 0.356 H -60.6 -40.7 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 ASN A:73 A:73 60.0 0.375 H -52.3 -49.2 15.0 0.094 0.281 B:P08263:0.281
 HOH
 3.405
 CB
 O
ASN B:73 B:73 60.0 0.375 H -48.9 -51.7 13.0 0.081 0.294 A:P08263:0.294
 HOH
 2.886
 OD1
 O
ASN C:73 C:73 63.0 0.394 H -51.0 -51.3 NA NA NA
ASN D:73 D:73 61.0 0.381 H -48.4 -55.2 NA NA NA
ASN E:73 E:73 58.0 0.362 H -56.7 -42.8 NA NA NA
ASN F:73 F:73 54.0 0.338 H -60.4 -30.7 NA NA NA
ASN G:73 G:73 56.0 0.35 H -63.2 -48.3 NA NA NA
ASN H:73 H:73 64.0 0.4 H -57.5 -45.3 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 ASN A:73 A:73 60.0 0.375 H -63.1 -41.7 15.0 0.094 0.281 B:P08263:0.281
 HOH
 2.647
 OD1
 O
ASN B:73 B:73 61.0 0.381 H -60.3 -48.6 15.0 0.094 0.287 A:P08263:0.287
 HOH
 2.996
 ND2
 O
ASN C:73 C:73 60.0 0.375 H -62.5 -39.5 NA NA NA
ASN D:73 D:73 58.0 0.362 H -54.9 -41.6 NA NA NA
ASN E:73 E:73 60.0 0.375 H -67.0 -41.7 NA NA NA
ASN F:73 F:73 60.0 0.375 H -62.5 -40.4 NA NA NA
ASN G:73 G:73 58.0 0.362 H -66.5 -39.5 NA NA NA
ASN H:73 H:73 63.0 0.394 H -60.9 -43.3 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 ASN A:73 A:73 60.0 0.375 H -61.1 -43.7 16.0 0.1 0.275 B:P08263:0.275
 HOH
 7.478
 O
 O
ASN B:73 B:73 62.0 0.388 H -59.6 -41.6 16.0 0.1 0.288 A:P08263:0.287
 HOH
 7.518
 O
 O
ASN C:73 C:73 58.0 0.362 H -54.8 -36.9 NA NA NA
ASN D:73 D:73 59.0 0.369 H -53.7 -45.9 NA NA NA
ASN E:73 E:73 61.0 0.381 H -61.8 -44.8 NA NA NA
ASN F:73 F:73 59.0 0.369 H -64.0 -44.6 NA NA NA
ASN G:73 G:73 58.0 0.362 H -63.0 -43.6 NA NA NA
ASN H:73 H:73 56.0 0.35 H -60.4 -44.9 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 ASN A:73 A:73 59.0 0.369 H -55.1 -46.1 13.0 0.081 0.288 B:P08263+P04903:0.287
 HOH
 2.802
 OD1
 O
ASN B:73 B:73 58.0 0.362 H -64.1 -43.6 13.0 0.081 0.281 A:P08263+P04903:0.281
 HOH
 2.798
 ND2
 O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 ASN A:73 A:73 62.0 0.388 H -61.0 -42.7 15.0 0.094 0.294 A:P08263+P04903:0.294
 CL
CL
HOH
 3.030
2.801
2.817
 ND2
ND2
OD1
 CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 ASN A:73 A:73 54.0 0.338 H -61.6 -40.3
af-p08263-f1 1 P08263 90.09 6e-146 ASN A:73 A:73 46.0 0.287 H -62.5 -42.1
af-p09210-f1 1 P09210 88.74 1e-143 ASN A:73 A:73 57.0 0.356 H -62.6 -41.5
af-q16772-f1 1 Q16772 85.59 7e-139 ASN A:73 A:73 57.0 0.356 H -62.2 -42.6