Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52701103 . G A CCDS4946.1:NM_153699.1:c.203aCc>aTc_NP_714543.1:p.68T>I Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 THR A:68 A:68 26.0 0.186 H -47.4 -48.3 26.0 0.186 0.0 GSH
HED
HOH
 3.027
3.777
2.983
 OG1
CG2
OG1
 O11
O1
O
THR B:68 B:68 27.0 0.193 H -45.0 -51.8 27.0 0.193 0.0 GSH
HED
HOH
 2.855
3.702
2.767
 OG1
CG2
OG1
 O11
O6
O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 THR A:68 A:68 30.0 0.214 H -40.9 -53.3 30.0 0.214 0.0 HED
HOH
 3.431
2.786
 CG2
OG1
 O1
O
THR B:68 B:68 27.0 0.193 H -49.0 -47.5 27.0 0.193 0.0 HED
HOH
 3.991
2.829
 CG2
OG1
 O1
O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 THR A:68 A:68 29.0 0.207 H -52.0 -44.4 29.0 0.207 0.0 CL
ABY
HOH
 3.026
5.705
3.014
 OG1
N
OG1
 CL
N1
O
THR B:68 B:68 28.0 0.2 H -47.7 -47.4 28.0 0.2 0.0 CL
ABY
HOH
 3.095
5.744
2.946
 OG1
N
OG1
 CL
CA1
O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 THR A:68 A:68 27.0 0.193 H -39.6 -48.1 27.0 0.193 0.0 P9H
GOL
GOL
HOH
 2.687
6.236
9.957
2.482
 OG1
CB
CB
OG1
 O2
O2
O1
O
THR B:68 B:68 27.0 0.193 H -46.0 -49.4 27.0 0.193 0.0 GOL
P9H
HOH
 5.919
2.822
2.712
 CB
N
OG1
 O2
O1
O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 THR A:68 A:68 26.0 0.186 H -39.0 -45.8 26.0 0.186 0.0 GTX
HOH
 2.718
2.814
 OG1
OG1
 O12
O
THR B:68 B:68 23.0 0.164 H -41.8 -50.2 23.0 0.164 0.0 GTX
HOH
 2.508
3.371
 OG1
N
 O12
O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 THR A:68 A:68 25.0 0.179 H -40.1 -49.2 25.0 0.179 0.0 GTX
HOH
 2.932
3.096
 N
OG1
 O11
O
THR B:68 B:68 27.0 0.193 H -42.7 -52.1 27.0 0.193 0.0 GTX
HOH
 2.967
3.378
 OG1
N
 O12
O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 THR A:68 A:68 30.0 0.214 H -44.2 -44.4 30.0 0.214 0.0 HOH
 2.724
 N
 O
THR B:68 B:68 30.0 0.214 H -57.3 -49.8 30.0 0.214 0.0 HOH
 2.953
 OG1
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 THR A:67 A:68 26.0 0.186 H -42.4 -57.1 26.0 0.186 0.0 GSH
EAA
BME
BME
BME
HOH
 3.087
7.484
4.613
3.833
9.509
3.127
 N
OG1
CG2
CG2
C
CG2
 O11
O1
O1
O1
O1
O
THR B:67 B:68 28.0 0.2 H -43.7 -57.0 28.0 0.2 0.0 BME
GSH
EAA
BME
BME
HOH
 9.502
3.052
7.382
4.523
4.142
3.579
 C
N
OG1
CG2
CG2
N
 O1
O12
O1
O1
O1
O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 THR A:67 A:68 30.0 0.214 H -42.8 -49.3 30.0 0.214 0.0 HOH
 3.080
 OG1
 O
THR B:67 B:68 29.0 0.207 H -42.8 -49.3 29.0 0.207 0.0 HOH
 3.080
 OG1
 O
THR C:67 C:68 28.0 0.2 H -42.8 -49.3 NA NA NA
THR D:67 D:68 30.0 0.214 H -42.8 -49.3 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 THR A:67 A:68 31.0 0.221 H -43.3 -51.9 31.0 0.221 0.0 EAA
HOH
 6.859
3.180
 OG1
N
 O
O
THR B:67 B:68 31.0 0.221 H -43.3 -51.9 31.0 0.221 0.0 EAA
HOH
 6.859
3.180
 OG1
N
 O
O
THR C:67 C:68 31.0 0.221 H -43.3 -51.9 NA NA NA
THR D:67 D:68 30.0 0.214 H -43.3 -51.9 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 THR A:67 A:68 35.0 0.25 H -42.1 -57.3 35.0 0.25 0.0 GSB
 2.957
 OG1
 O12
THR B:67 B:68 34.0 0.243 H -42.1 -57.2 34.0 0.243 0.0 GSB
 2.958
 OG1
 O12
THR C:67 C:68 35.0 0.25 H -42.0 -57.3 NA NA NA
THR D:67 D:68 36.0 0.257 H -42.0 -57.3 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 THR A:67 A:68 25.0 0.179 H -43.6 -51.1 25.0 0.179 0.0 GTX
HOH
 2.867
2.889
 OG1
OG1
 O12
O
THR B:67 B:68 25.0 0.179 H -41.7 -49.3 25.0 0.179 0.0 GTX
HOH
 2.802
2.748
 OG1
OG1
 O12
O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 THR A:67 A:68 32.0 0.229 H -56.5 -37.9 32.0 0.229 0.0 HOH
 3.434
 OG1
 O
THR B:67 B:68 32.0 0.229 H -48.2 -44.2 32.0 0.229 0.0 HOH
 2.738
 OG1
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 THR A:67 A:68 27.0 0.193 H -42.5 -50.3 27.0 0.193 0.0 GTX
GOL
GOL
GOL
HOH
 2.802
3.670
6.099
9.760
2.887
 OG1
CG2
CB
CB
OG1
 O11
O3
O2
O3
O
THR B:67 B:68 26.0 0.186 H -42.2 -50.7 26.0 0.186 0.0 GOL
GTX
GOL
HOH
 9.910
2.743
6.398
2.827
 CB
OG1
CB
OG1
 O1
O12
O2
O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:67 A:68 27.0 0.193 H -48.4 -46.5 27.0 0.193 0.0 HOH
 3.417
 N
 O
THR B:67 B:68 28.0 0.2 H -42.6 -49.0 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:67 A:68 27.0 0.193 H -51.0 -44.8 27.0 0.193 0.0 HOH
 2.860
 OG1
 O
THR B:67 B:68 28.0 0.2 H -51.2 -43.6 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:67 A:68 28.0 0.2 H -45.4 -47.9 28.0 0.2 0.0 MPD
MES
HOH
 9.804
8.219
2.786
 OG1
OG1
OG1
 HO2
O2S
O
THR B:67 B:68 27.0 0.193 H -48.8 -45.9 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 THR A:67 A:68 16.0 0.114 H -43.3 -49.5 16.0 0.114 0.0 BWS
GSN
EDO
EDO
EDO
EDO
HOH
 2.790
2.788
9.066
5.087
3.487
9.832
2.978
 OG1
OG1
OG1
CG2
CG2
CG2
OG1
 OXT
OXT
HO1
HO2
HO1
HO2
O
THR B:67 B:68 16.0 0.114 H -40.8 -50.4 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 THR A:68 A:68 30.0 0.214 H -58.2 -38.9 30.0 0.214 0.0 HOH
 2.778
 OG1
 O
THR B:68 B:68 29.0 0.207 H -45.7 -41.7 29.0 0.207 0.0 HOH
 3.016
 N
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 THR A:68 A:68 27.0 0.193 H -39.7 -50.9 27.0 0.193 0.0 GTX
HOH
 2.754
2.847
 OG1
OG1
 O12
O
THR B:68 B:68 25.0 0.179 H -38.0 -52.1 25.0 0.179 0.0 GTX
HOH
 2.776
2.851
 OG1
OG1
 O12
O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 THR A:68 A:68 31.0 0.221 H -50.1 -48.3 31.0 0.221 0.0 HOH
 3.040
 N
 O
THR B:68 B:68 27.0 0.193 H -56.9 -42.3 27.0 0.193 0.0 HOH
 2.839
 N
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 GLU A:68 A:68 43.0 0.226 H -50.2 -45.1 43.0 0.226 0.0 CL
ABY
HOH
 3.098
5.623
2.506
 N
N
OE1
 CL
CA1
O
GLU B:68 B:68 43.0 0.226 H -49.2 -46.0 43.0 0.226 0.0 CL
ABY
HOH
 3.129
5.657
2.715
 N
N
OE1
 CL
CA1
O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 THR A:68 A:68 27.0 0.193 H -40.3 -60.0 27.0 0.193 0.0 GTX
HOH
 2.767
3.106
 OG1
OG1
 O12
O
THR B:68 B:68 30.0 0.214 H -48.6 -51.8 30.0 0.214 0.0 GTX
HOH
 2.894
2.998
 OG1
OG1
 O12
O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 THR A:67 A:68 27.0 0.193 H -51.4 -37.7 27.0 0.193 0.0 HOH
 2.793
 OG1
 O
THR B:67 B:68 28.0 0.2 H -48.9 -45.4 28.0 0.2 0.0 HOH
 3.065
 OG1
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 THR A:67 A:68 28.0 0.2 H -39.8 -55.1 28.0 0.2 0.0 GTX
HOH
 2.802
2.920
 OG1
OG1
 O12
O
THR B:67 B:68 25.0 0.179 H -44.7 -54.4 25.0 0.179 0.0 GTX
HOH
 2.909
2.970
 OG1
OG1
 O12
O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 THR A:71 A:68 27.0 0.193 H -45.7 -49.2 27.0 0.193 0.0 GSH
CL
HOH
 2.993
7.549
2.587
 OG1
O
OG1
 O12
CL
O
THR B:71 B:68 30.0 0.214 H -43.1 -52.7 30.0 0.214 0.0 GSH
CL
HOH
 2.674
7.607
2.971
 OG1
O
OG1
 O12
CL
O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 GLU A:67 A:68 41.0 0.216 H -45.1 -46.5 41.0 0.216 0.0 HOH
 3.319
 N
 O
GLU B:67 B:68 46.0 0.242 H -47.6 -46.0 46.0 0.242 0.0 HOH
 2.448
 OE1
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 THR A:68 A:68 28.0 0.2 H -46.2 -45.6 28.0 0.2 0.0 ASD
HOH
 8.286
2.582
 OG1
OG1
 O2
O
THR B:68 B:68 26.0 0.186 H -53.2 -44.3 26.0 0.186 0.0 ASD
HOH
 8.177
2.782
 OG1
N
 O2
O
THR C:68 C:68 30.0 0.214 H -52.7 -45.5 NA NA NA
THR D:68 D:68 28.0 0.2 H -42.7 -48.6 NA NA NA
THR E:68 E:68 26.0 0.186 H -56.2 -47.0 NA NA NA
THR F:68 F:68 26.0 0.186 H -53.1 -41.5 NA NA NA
THR G:68 G:68 29.0 0.207 H -42.1 -46.0 NA NA NA
THR H:68 H:68 28.0 0.2 H -35.9 -52.7 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 THR A:68 A:68 26.0 0.186 H -38.3 -40.5 26.0 0.186 0.0 GSH
HOH
 2.916
3.494
 N
N
 O11
O
THR B:68 B:68 24.0 0.171 H -41.9 -43.0 24.0 0.171 0.0 GSH
HOH
 3.070
3.035
 OG1
N
 O12
O
THR C:68 C:68 28.0 0.2 H -41.9 -41.8 NA NA NA
THR D:68 D:68 28.0 0.2 H -40.5 -46.7 NA NA NA
THR E:68 E:68 27.0 0.193 H -35.0 -52.7 NA NA NA
THR F:68 F:68 29.0 0.207 H -35.1 -46.6 NA NA NA
THR G:68 G:68 27.0 0.193 H -41.5 -50.0 NA NA NA
THR H:68 H:68 25.0 0.179 H -52.8 -46.4 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 THR A:67 A:68 29.0 0.207 H -37.9 -51.4 29.0 0.207 0.0 GVX
EDO
EDO
HOH
 2.699
4.167
5.543
2.903
 OG1
CG2
CG2
OG1
 O01
O2
C1
O
THR B:67 B:68 24.0 0.171 H -40.7 -53.6 24.0 0.171 0.0 GVX
HOH
 2.839
2.923
 N
OG1
 O03
O
THR C:67 C:68 28.0 0.2 H -44.8 -52.4 NA NA NA
THR D:67 D:68 29.0 0.207 H -48.8 -48.1 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 THR A:65 A:68 26.0 0.186 H -37.9 -53.2 26.0 0.186 0.0 LZ6
HOH
 2.650
2.786
 OG1
OG1
 O36
O
THR B:65 B:68 24.0 0.171 H -38.4 -57.2 24.0 0.171 0.0 LZ6
HOH
 2.775
2.739
 OG1
OG1
 O36
O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 THR A:68 A:68 23.0 0.164 H -48.3 -51.9 23.0 0.164 0.0 GSH
HOH
 2.461
3.761
 OG1
OG1
 O11
O
THR B:68 B:68 22.0 0.157 H -57.8 -46.2 22.0 0.157 0.0 GSH
HOH
 2.371
3.013
 OG1
N
 O11
O
THR C:68 C:68 22.0 0.157 H -47.5 -48.9 NA NA NA
THR D:68 D:68 29.0 0.207 H -38.9 -46.9 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 THR A:68 A:68 28.0 0.2 H -36.5 -56.9 28.0 0.2 0.0 GSH
HOH
 2.871
3.336
 N
N
 O11
O
THR B:68 B:68 27.0 0.193 H -40.3 -54.1 27.0 0.193 0.0 GSH
HOH
 2.814
3.671
 OG1
N
 O11
O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 THR A:68 A:68 26.0 0.186 H -52.8 -47.3 26.0 0.186 0.0 GSH
ASD
HOH
 3.022
9.609
3.163
 OG1
OG1
N
 O11
C19
O
THR B:68 B:68 27.0 0.193 H -37.0 -55.2 27.0 0.193 0.0 GSH
ASD
HOH
 2.958
9.089
3.284
 OG1
OG1
N
 O11
C19
O
THR C:68 C:68 23.0 0.164 H -45.3 -53.0 NA NA NA
THR D:68 D:68 28.0 0.2 H -46.8 -48.4 NA NA NA
THR E:68 E:68 27.0 0.193 H -40.0 -52.1 NA NA NA
THR F:68 F:68 28.0 0.2 H -49.4 -46.2 NA NA NA
THR G:68 G:68 29.0 0.207 H -44.3 -47.7 NA NA NA
THR H:68 H:68 25.0 0.179 H -42.1 -52.7 NA NA NA
THR I:68 I:68 29.0 0.207 H -48.4 -50.9 NA NA NA
THR J:68 J:68 25.0 0.179 H -50.5 -48.8 NA NA NA
THR K:68 K:68 28.0 0.2 H -43.5 -51.8 NA NA NA
THR L:68 L:68 26.0 0.186 H -46.7 -50.1 NA NA NA
THR M:68 M:68 25.0 0.179 H -48.6 -47.9 NA NA NA
THR N:68 N:68 26.0 0.186 H -47.3 -51.0 NA NA NA
THR O:68 O:68 28.0 0.2 H -45.5 -50.6 NA NA NA
THR P:68 P:68 24.0 0.171 H -49.5 -49.7 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 THR A:68 A:68 28.0 0.2 H -45.9 -40.9 28.0 0.2 0.0 HOH
 3.247
 N
 O
THR B:68 B:68 25.0 0.179 H -50.5 -46.3 25.0 0.179 0.0 GSH
HOH
 2.714
3.190
 OG1
N
 O12
O
THR C:68 C:68 31.0 0.221 H -44.8 -47.6 NA NA NA
THR D:68 D:68 26.0 0.186 H -41.8 -53.0 NA NA NA
THR E:68 E:68 26.0 0.186 H -33.7 -53.4 NA NA NA
THR F:68 F:68 27.0 0.193 H -34.7 -58.3 NA NA NA
THR G:68 G:68 31.0 0.221 H -53.5 -39.4 NA NA NA
THR H:68 H:68 32.0 0.229 H -41.9 -48.0 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 THR A:68 A:68 27.0 0.193 H -41.8 -53.2 27.0 0.193 0.0 GSH
HOH
 2.877
2.949
 OG1
OG1
 O11
O
THR B:68 B:68 24.0 0.171 H -41.7 -48.5 24.0 0.171 0.0 GSH
HOH
 2.807
2.967
 OG1
OG1
 O12
O
THR C:68 C:68 27.0 0.193 H -45.0 -50.5 NA NA NA
THR D:68 D:68 25.0 0.179 H -49.8 -43.2 NA NA NA
THR E:68 E:68 26.0 0.186 H -42.7 -47.1 NA NA NA
THR F:68 F:68 23.0 0.164 H -48.1 -48.3 NA NA NA
THR G:68 G:68 25.0 0.179 H -44.6 -48.8 NA NA NA
THR H:68 H:68 25.0 0.179 H -40.5 -45.5 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 THR A:68 A:68 25.0 0.179 H -50.8 -48.0 25.0 0.179 0.0 BOB
HOH
 2.909
3.359
 OG1
N
 O11
O
THR B:68 B:68 26.0 0.186 H -43.3 -53.8 26.0 0.186 0.0 BOB
HOH
 2.986
3.127
 OG1
N
 O11
O
THR C:68 C:68 28.0 0.2 H -45.2 -50.2 NA NA NA
THR D:68 D:68 25.0 0.179 H -40.7 -51.8 NA NA NA
THR E:68 E:68 27.0 0.193 H -47.9 -42.8 NA NA NA
THR F:68 F:68 26.0 0.186 H -47.0 -55.6 NA NA NA
THR G:68 G:68 30.0 0.214 H -39.9 -49.3 NA NA NA
THR H:68 H:68 26.0 0.186 H -34.6 -53.4 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 THR A:68 A:68 21.0 0.15 H -47.0 -48.0 21.0 0.15 0.0 GSH
HOH
 2.839
2.991
 OG1
CG2
 O12
O
THR B:68 B:68 23.0 0.164 H -46.0 -49.0 23.0 0.164 0.0 HOH
 2.761
 OG1
 O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 THR A:68 A:68 35.0 0.25 H -57.4 -34.9 35.0 0.25 0.0 CL
CL
HOH
 7.976
7.573
2.640
 C
O
OG1
 CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 THR A:68 A:68 34.0 0.243 H -50.4 -45.8
af-p08263-f1 1 P08263 90.09 6e-146 THR A:68 A:68 25.0 0.179 H -48.6 -46.4
af-p09210-f1 1 P09210 88.74 1e-143 THR A:68 A:68 27.0 0.193 H -48.9 -45.9
af-q16772-f1 1 Q16772 85.59 7e-139 THR A:68 A:68 24.0 0.171 H -49.1 -45.5