Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52701143 . C A CCDS4946.1:NM_153699.1:c.163Gta>Tta_NP_714543.1:p.55V>L Homo sapiens glutathione S-transferase alpha 5 (GSTA5), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1pkw 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 VAL A:55 A:55 16.0 0.103 S -113.2 165.3 16.0 0.103 0.0 GSH
HOH
 2.767
3.507
 O
C
 N2
O
VAL B:55 B:55 16.0 0.103 S -110.3 166.8 16.0 0.103 0.0 GSH
HOH
 2.777
3.425
 O
C
 N2
O
1pkz 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 VAL A:55 A:55 17.0 0.11 S -100.7 164.3 17.0 0.11 0.0 HOH
 3.205
 N
 O
VAL B:55 B:55 19.0 0.123 S -105.5 165.0 19.0 0.123 0.0 HOH
 3.038
 N
 O
1pl1 1 P08263 90.09 1e-145 X-RAY
 2004-06-22 VAL A:55 A:55 15.0 0.097 S -115.1 166.0 15.0 0.097 0.0 CL
ABY
HOH
 4.628
2.822
3.472
 O
O
C
 CL
N2
O
VAL B:55 B:55 17.0 0.11 S -118.9 168.1 17.0 0.11 0.0 CL
ABY
HOH
 4.595
2.792
3.469
 O
O
C
 CL
N2
O
6yaw 1 P08263 90.09 1e-145 X-RAY
 2020-08-26 VAL A:55 A:55 16.0 0.103 S -106.4 164.2 16.0 0.103 0.0 P9H
GOL
HOH
 2.796
8.394
3.403
 O
O
C
 N
O3
O
VAL B:55 B:55 17.0 0.11 S -110.4 159.2 17.0 0.11 0.0 GOL
P9H
HOH
 8.410
2.659
3.432
 O
O
C
 O3
N
O
2r6k 1 P08263 89.64 2e-145 X-RAY
 2008-08-19 VAL A:55 A:55 18.0 0.116 S -101.3 167.7 18.0 0.116 0.0 GTX
HOH
 2.541
7.141
 O
O
 N2
O
VAL B:55 B:55 14.0 0.09 S -110.7 163.8 14.0 0.09 0.0 GTX
HOH
 2.492
7.313
 O
O
 N2
O
2r3x 1 P08263 90.09 3e-145 X-RAY
 2007-12-18 VAL A:55 A:55 17.0 0.11 S -112.0 165.9 17.0 0.11 0.0 GTX
HOH
 2.626
3.519
 O
C
 N2
O
VAL B:55 B:55 14.0 0.09 S -106.5 167.1 14.0 0.09 0.0 GTX
HOH
 2.690
3.432
 O
C
 N2
O
3zfl 1 P08263 89.64 4e-145 X-RAY
 2012-12-19 VAL A:55 A:55 21.0 0.135 S -105.8 170.3 21.0 0.135 0.0 HOH
 2.802
 N
 O
VAL B:55 B:55 21.0 0.135 -93.7 171.9 21.0 0.135 0.0 HOH
 2.850
 O
 O
1gse 1 P08263 90.05 7e-145 X-RAY
 1995-09-15 VAL A:54 A:55 20.0 0.129 S -121.0 163.8 20.0 0.129 0.0 GSH
EAA
HOH
 2.688
5.663
3.566
 O
O
C
 N2
C11
O
VAL B:54 B:55 21.0 0.135 S -118.3 164.7 21.0 0.135 0.0 GSH
EAA
HOH
 2.554
5.561
3.491
 O
O
C
 N2
C11
O
1gsd 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 VAL A:54 A:55 23.0 0.148 S -118.0 164.0 23.0 0.148 0.0 HOH
 2.922
 N
 O
VAL B:54 B:55 20.0 0.129 S -118.0 164.0 20.0 0.129 0.0 HOH
 2.922
 N
 O
VAL C:54 C:55 21.0 0.135 S -117.9 164.1 NA NA NA
VAL D:54 D:55 21.0 0.135 S -118.0 164.0 NA NA NA
1gsf 1 P08263 90.05 8e-145 X-RAY
 1995-09-15 VAL A:54 A:55 21.0 0.135 S -124.5 167.7 21.0 0.135 0.0 EAA
HOH
 2.655
3.011
 O
N
 OXT
O
VAL B:54 B:55 23.0 0.148 S -124.5 167.7 23.0 0.148 0.0 EAA
HOH
 2.655
3.011
 O
N
 OXT
O
VAL C:54 C:55 22.0 0.142 S -124.4 167.8 NA NA NA
VAL D:54 D:55 21.0 0.135 S -124.5 167.8 NA NA NA
1guh 1 P08263 90.05 8e-145 X-RAY
 1993-10-31 VAL A:54 A:55 16.0 0.103 S -121.7 155.6 16.0 0.103 0.0 GSB
 2.860
 O
 N2
VAL B:54 B:55 16.0 0.103 S -121.6 155.6 16.0 0.103 0.0 GSB
 2.859
 O
 N2
VAL C:54 C:55 17.0 0.11 S -121.6 155.7 NA NA NA
VAL D:54 D:55 16.0 0.103 S -121.7 155.6 NA NA NA
1k3l 1 P08263 90.05 8e-145 X-RAY
 2002-10-23 VAL A:54 A:55 17.0 0.11 S -113.6 161.6 17.0 0.11 0.0 GTX
HOH
 2.611
3.540
 O
C
 N2
O
VAL B:54 B:55 15.0 0.097 S -111.5 162.2 15.0 0.097 0.0 GTX
HOH
 2.614
3.588
 O
C
 N2
O
1k3o 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 VAL A:54 A:55 23.0 0.148 S -102.7 162.7 23.0 0.148 0.0 HOH
 2.881
 O
 O
VAL B:54 B:55 26.0 0.168 S -103.8 161.6 26.0 0.168 0.0 HOH
 3.193
 N
 O
1k3y 1 P08263 90.05 8e-145 X-RAY
 2002-10-30 VAL A:54 A:55 16.0 0.103 S -113.4 159.5 16.0 0.103 0.0 GTX
GOL
HOH
 2.733
8.217
3.591
 O
O
C
 N2
O3
O
VAL B:54 B:55 15.0 0.097 S -110.5 164.2 15.0 0.097 0.0 GTX
GOL
HOH
 2.725
8.365
3.528
 O
O
C
 N2
O1
O
6ato 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 VAL A:54 A:55 14.0 0.09 S -111.5 166.0 14.0 0.09 0.0 GSH
MPD
MPD
HOH
 2.650
6.437
9.060
3.627
 O
O
CG1
C
 N2
H53
H13
O
VAL B:54 B:55 16.0 0.103 S -113.6 167.3 NA NA NA
6atp 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 VAL A:54 A:55 18.0 0.116 S -102.3 163.0 18.0 0.116 0.0 MPD
MPD
HOH
 9.737
8.858
3.023
 N
CG1
N
 H53
HM2
O
VAL B:54 B:55 18.0 0.116 S -104.8 165.5 NA NA NA
6atq 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 VAL A:54 A:55 15.0 0.097 S -99.8 163.7 15.0 0.097 0.0 MPD
MES
MPD
HOH
 6.630
5.133
9.354
3.033
 CG2
CG2
CG1
N
 H53
H62
HM3
O
VAL B:54 B:55 16.0 0.103 S -115.9 165.7 NA NA NA
6atr 1 P08263 90.05 8e-145 X-RAY
 2018-09-12 VAL A:54 A:55 0.0 0.0 S -113.2 165.4 0.0 0.0 0.0 BWS
GSN
EDO
EDO
HOH
 2.741
2.729
7.506
9.031
3.554
 O
O
O
O
C
 NAJ
NAJ
O1
HO1
O
VAL B:54 B:55 0.0 0.0 S -111.8 164.2 NA NA NA
3zfb 1 P08263 89.64 8e-145 X-RAY
 2012-12-19 VAL A:55 A:55 20.0 0.129 S -101.5 164.9 20.0 0.129 0.0 HOH
 3.713
 C
 O
VAL B:55 B:55 19.0 0.123 -102.4 167.8 19.0 0.123 0.0 HOH
 2.746
 O
 O
1ydk 1 P08263 89.64 8e-145 X-RAY
 2005-06-07 VAL A:55 A:55 20.0 0.129 S -109.1 158.0 20.0 0.129 0.0 GTX
HOH
 2.690
3.514
 O
C
 N2
O
VAL B:55 B:55 17.0 0.11 S -109.6 162.7 17.0 0.11 0.0 GTX
HOH
 2.729
3.515
 O
C
 N2
O
3u6v 1 P08263 89.64 8e-145 X-RAY
 2011-10-26 VAL A:55 A:55 19.0 0.123 S -103.4 166.9 19.0 0.123 0.0 HOH
 2.939
 O
 O
VAL B:55 B:55 20.0 0.129 S -99.4 162.3 20.0 0.129 0.0 HOH
 2.610
 O
 O
1pl2 1 P08263 89.64 2e-144 X-RAY
 2004-06-22 VAL A:55 A:55 15.0 0.097 S -111.6 166.0 15.0 0.097 0.0 CL
ABY
HOH
 4.716
2.890
3.554
 O
O
C
 CL
N2
O
VAL B:55 B:55 17.0 0.11 S -118.1 166.1 17.0 0.11 0.0 CL
ABY
HOH
 4.573
2.823
3.507
 O
O
C
 CL
N2
O
3l0h 1 P08263 89.64 3e-144 X-RAY
 2010-01-12 VAL A:55 A:55 15.0 0.097 S -101.8 166.6 15.0 0.097 0.0 GTX
HOH
 2.767
3.405
 O
C
 N2
O
VAL B:55 B:55 16.0 0.103 S -105.0 165.8 16.0 0.103 0.0 GTX
HOH
 2.653
3.504
 O
C
 N2
O
3q74 1 P08263 89.59 6e-144 X-RAY
 2011-01-12 VAL A:54 A:55 21.0 0.135 S -102.2 164.4 21.0 0.135 0.0 HOH
 2.791
 O
 O
VAL B:54 B:55 21.0 0.135 S -103.9 163.6 21.0 0.135 0.0 HOH
 2.458
 O
 O
3ktl 1 P08263 89.59 6e-144 X-RAY
 2009-12-22 VAL A:54 A:55 18.0 0.116 S -112.6 165.1 18.0 0.116 0.0 GTX
HOH
 2.636
3.521
 O
C
 N2
O
VAL B:54 B:55 16.0 0.103 S -113.8 165.4 16.0 0.103 0.0 GTX
HOH
 2.463
3.524
 O
C
 N2
O
1usb 1 P08263 89.59 7e-144 X-RAY
 2004-09-01 VAL A:58 A:55 22.0 0.142 S -106.2 163.6 22.0 0.142 0.0 GSH
HOH
 2.687
3.526
 O
C
 N2
O
VAL B:58 B:55 24.0 0.155 S -112.1 160.3 24.0 0.155 0.0 GSH
HOH
 2.630
3.552
 O
C
 N2
O
1xwg 1 P08263 89.59 8e-144 X-RAY
 2005-11-01 VAL A:54 A:55 18.0 0.116 S -101.0 160.9 18.0 0.116 0.0 HOH
 2.994
 N
 O
VAL B:54 B:55 22.0 0.142 S -105.6 165.2 22.0 0.142 0.0 HOH
 2.816
 O
 O
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 VAL A:55 A:55 18.0 0.116 S -95.7 161.8 18.0 0.116 0.0 ASD
HOH
 6.105
3.169
 O
O
 C18
O
VAL B:55 B:55 14.0 0.09 S -97.6 159.3 14.0 0.09 0.0 ASD
HOH
 6.047
2.931
 O
O
 C18
O
VAL C:55 C:55 17.0 0.11 S -107.0 158.5 NA NA NA
VAL D:55 D:55 15.0 0.097 S -97.0 159.3 NA NA NA
VAL E:55 E:55 17.0 0.11 S -100.5 158.8 NA NA NA
VAL F:55 F:55 16.0 0.103 S -109.6 156.5 NA NA NA
VAL G:55 G:55 19.0 0.123 S -111.5 158.7 NA NA NA
VAL H:55 H:55 17.0 0.11 S -116.0 159.1 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 VAL A:55 A:55 17.0 0.11 S -106.5 162.4 17.0 0.11 0.0 GSH
HOH
 2.941
3.874
 O
C
 N2
O
VAL B:55 B:55 20.0 0.129 S -102.2 165.5 20.0 0.129 0.0 GSH
HOH
 2.979
3.634
 O
C
 N2
O
VAL C:55 C:55 19.0 0.123 -104.8 165.3 NA NA NA
VAL D:55 D:55 19.0 0.123 S -120.4 163.0 NA NA NA
VAL E:55 E:55 20.0 0.129 S -109.9 164.8 NA NA NA
VAL F:55 F:55 18.0 0.116 S -103.0 160.6 NA NA NA
VAL G:55 G:55 17.0 0.11 -106.4 166.8 NA NA NA
VAL H:55 H:55 18.0 0.116 S -106.2 160.2 NA NA NA
5jcu 1 P08263 89.59 5e-143 X-RAY
 2016-10-12 VAL A:54 A:55 20.0 0.129 S -110.9 169.2 20.0 0.129 0.0 GVX
EDO
HOH
 2.732
9.809
3.292
 O
O
C
 N10
O2
O
VAL B:54 B:55 17.0 0.11 S -109.8 165.0 17.0 0.11 0.0 GVX
HOH
 2.605
3.354
 O
C
 N10
O
VAL C:54 C:55 19.0 0.123 S -117.6 166.2 NA NA NA
VAL D:54 D:55 17.0 0.11 S -107.6 167.9 NA NA NA
4hj2 1 P08263 89.86 1e-141 X-RAY
 2013-03-27 VAL A:52 A:55 18.0 0.116 S -123.7 164.8 18.0 0.116 0.0 LZ6
HOH
 2.711
3.426
 O
C
 N29
O
VAL B:52 B:55 16.0 0.103 S -122.3 166.5 16.0 0.103 0.0 LZ6
HOH
 2.732
4.584
 O
N
 N29
O
4acs 1 P09210 87.78 2e-140 X-RAY
 2011-12-28 VAL A:55 A:55 18.0 0.116 S -113.6 165.9 18.0 0.116 0.0 GSH
HOH
 2.592
3.426
 O
C
 N2
O
VAL B:55 B:55 17.0 0.11 S -125.9 161.7 17.0 0.11 0.0 GSH
HOH
 2.968
3.139
 O
C
 N2
O
VAL C:55 C:55 18.0 0.116 S -129.9 144.4 NA NA NA
VAL D:55 D:55 19.0 0.123 S -109.6 159.0 NA NA NA
1tdi 1 Q16772 85.59 2e-138 X-RAY
 2005-01-18 VAL A:55 A:55 23.0 0.148 S -126.6 163.1 23.0 0.148 0.0 GSH
HOH
 2.691
3.428
 O
C
 N2
O
VAL B:55 B:55 20.0 0.129 S -120.9 166.1 20.0 0.129 0.0 GSH
HOH
 2.726
3.499
 O
C
 N2
O
2vcv 1 Q16772 85.59 2e-138 X-RAY
 2008-10-28 VAL A:55 A:55 20.0 0.129 S -116.1 165.8 20.0 0.129 0.0 GSH
ASD
HOH
 2.762
6.745
3.538
 O
O
C
 N2
C4
O
VAL B:55 B:55 20.0 0.129 S -106.8 163.5 20.0 0.129 0.0 GSH
ASD
HOH
 2.608
6.797
3.372
 O
CG2
C
 N2
C6
O
VAL C:55 C:55 23.0 0.148 S -111.5 165.6 NA NA NA
VAL D:55 D:55 19.0 0.123 S -109.8 166.0 NA NA NA
VAL E:55 E:55 20.0 0.129 S -109.0 163.0 NA NA NA
VAL F:55 F:55 21.0 0.135 S -117.3 165.7 NA NA NA
VAL G:55 G:55 21.0 0.135 S -109.4 166.1 NA NA NA
VAL H:55 H:55 21.0 0.135 S -108.7 163.7 NA NA NA
VAL I:55 I:55 19.0 0.123 S -111.1 162.8 NA NA NA
VAL J:55 J:55 22.0 0.142 S -106.6 165.3 NA NA NA
VAL K:55 K:55 18.0 0.116 S -110.7 165.6 NA NA NA
VAL L:55 L:55 22.0 0.142 S -104.5 164.3 NA NA NA
VAL M:55 M:55 17.0 0.11 S -98.8 165.5 NA NA NA
VAL N:55 N:55 21.0 0.135 S -107.9 167.8 NA NA NA
VAL O:55 O:55 21.0 0.135 S -110.6 165.6 NA NA NA
VAL P:55 P:55 18.0 0.116 S -106.1 164.6 NA NA NA
3i69 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 VAL A:55 A:55 10.0 0.065 S -101.2 151.1 10.0 0.065 0.0 HOH
 3.850
 C
 O
VAL B:55 B:55 19.0 0.123 -104.9 165.3 19.0 0.123 0.0 GSH
HOH
 2.899
3.403
 O
C
 N2
O
VAL C:55 C:55 11.0 0.071 S -94.8 164.9 NA NA NA
VAL D:55 D:55 24.0 0.155 -110.6 168.7 NA NA NA
VAL E:55 E:55 21.0 0.135 -101.5 162.2 NA NA NA
VAL F:55 F:55 21.0 0.135 S -102.7 152.4 NA NA NA
VAL G:55 G:55 18.0 0.116 S -101.2 164.4 NA NA NA
VAL H:55 H:55 19.0 0.123 S -110.1 156.9 NA NA NA
3i6a 1 P08263 84.62 5e-135 X-RAY
 2009-09-01 VAL A:55 A:55 18.0 0.116 S -110.4 163.4 18.0 0.116 0.0 GSH
HOH
 2.908
3.655
 O
C
 N2
O
VAL B:55 B:55 18.0 0.116 S -106.9 161.4 18.0 0.116 0.0 GSH
HOH
 2.770
3.529
 O
C
 N2
O
VAL C:55 C:55 15.0 0.097 S -106.2 161.1 NA NA NA
VAL D:55 D:55 20.0 0.129 S -105.5 167.3 NA NA NA
VAL E:55 E:55 17.0 0.11 S -108.1 163.8 NA NA NA
VAL F:55 F:55 17.0 0.11 S -109.6 155.6 NA NA NA
VAL G:55 G:55 21.0 0.135 S -106.9 164.6 NA NA NA
VAL H:55 H:55 19.0 0.123 S -110.7 159.5 NA NA NA
3ik9 1 P08263 84.62 5e-135 X-RAY
 2010-06-23 VAL A:55 A:55 20.0 0.129 S -115.4 161.2 20.0 0.129 0.0 BOB
HOH
 2.797
3.677
 O
C
 N2
O
VAL B:55 B:55 15.0 0.097 -116.5 163.7 15.0 0.097 0.0 BOB
HOH
 2.841
4.573
 O
N
 N2
O
VAL C:55 C:55 22.0 0.142 S -109.4 161.1 NA NA NA
VAL D:55 D:55 19.0 0.123 S -114.7 162.7 NA NA NA
VAL E:55 E:55 21.0 0.135 S -121.0 161.3 NA NA NA
VAL F:55 F:55 23.0 0.148 S -117.5 158.2 NA NA NA
VAL G:55 G:55 20.0 0.129 S -115.4 161.9 NA NA NA
VAL H:55 H:55 18.0 0.116 S -105.9 159.6 NA NA NA
5lcz 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 VAL A:55 A:55 20.0 0.129 S -106.2 168.4 20.0 0.129 0.0 GSH
HOH
 2.676
3.375
 O
C
 N2
O
VAL B:55 B:55 25.0 0.161 S -103.9 161.0 25.0 0.161 0.0 HOH
 3.700
 C
 O
5ld0 1 P08263,P04903 81.08 3e-128 X-RAY
 2016-09-21 VAL A:55 A:55 25.0 0.161 S -106.7 164.3 25.0 0.161 0.0 HOH
 2.609
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q7rtv2-f1 1 Q7RTV2 100.0 1e-164 VAL A:55 A:55 22.0 0.142 S -105.3 160.1
af-p08263-f1 1 P08263 90.09 6e-146 VAL A:55 A:55 23.0 0.148 S -110.9 158.5
af-p09210-f1 1 P09210 88.74 1e-143 VAL A:55 A:55 20.0 0.129 S -109.2 158.7
af-q16772-f1 1 Q16772 85.59 7e-139 VAL A:55 A:55 20.0 0.129 S -109.2 160.7