Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52762672 . T A CCDS4947.1:NM_000847.4:c.497tAt>tTt_NP_000838.3:p.166Y>F Homo sapiens glutathione S-transferase alpha 3 (GSTA3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1tdi 1 Q16772 100.0 9e-164 X-RAY
 2005-01-18 TYR A:166 A:166 19.0 0.083 H -63.4 -41.1 19.0 0.083 0.0 HOH
 2.911
 OH
 O
TYR B:166 B:166 19.0 0.083 H -59.7 -45.7 19.0 0.083 0.0 HOH
 2.913
 OH
 O
2vcv 1 Q16772 100.0 9e-164 X-RAY
 2008-10-28 TYR A:166 A:166 14.0 0.061 H -71.7 -35.7 14.0 0.061 0.0 HOH
 2.731
 O
 O
TYR B:166 B:166 14.0 0.061 H -75.1 -44.1 14.0 0.061 0.0 HOH
 2.839
 OH
 O
TYR C:166 C:166 12.0 0.052 H -68.4 -36.0 NA NA NA
TYR D:166 D:166 14.0 0.061 H -66.3 -36.2 NA NA NA
TYR E:166 E:166 14.0 0.061 H -72.6 -33.1 NA NA NA
TYR F:166 F:166 16.0 0.07 H -68.4 -41.8 NA NA NA
TYR G:166 G:166 15.0 0.065 H -67.3 -38.5 NA NA NA
TYR H:166 H:166 15.0 0.065 H -73.0 -38.1 NA NA NA
TYR I:166 I:166 15.0 0.065 H -69.2 -42.0 NA NA NA
TYR J:166 J:166 14.0 0.061 H -64.1 -41.7 NA NA NA
TYR K:166 K:166 15.0 0.065 H -69.7 -38.2 NA NA NA
TYR L:166 L:166 13.0 0.057 H -70.4 -40.1 NA NA NA
TYR M:166 M:166 13.0 0.057 H -66.7 -40.2 NA NA NA
TYR N:166 N:166 14.0 0.061 H -66.9 -49.2 NA NA NA
TYR O:166 O:166 16.0 0.07 H -71.4 -40.7 NA NA NA
TYR P:166 P:166 16.0 0.07 H -72.0 -35.7 NA NA NA
1pkw 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 TYR A:166 A:166 34.0 0.148 H -70.9 -38.4 34.0 0.148 0.0 HED
HOH
 7.419
2.843
 CE2
OH
 C6
O
TYR B:166 B:166 36.0 0.157 H -68.2 -39.4 36.0 0.157 0.0 HED
HOH
 7.375
2.897
 CE2
O
 C1
O
1pkz 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 TYR A:166 A:166 35.0 0.152 H -70.8 -36.7 35.0 0.152 0.0 HED
HOH
 7.389
2.878
 CE2
OH
 C6
O
TYR B:166 B:166 39.0 0.17 H -68.2 -37.5 39.0 0.17 0.0 HED
HOH
 6.864
2.772
 CE2
O
 C2
O
1pl1 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 TYR A:166 A:166 35.0 0.152 H -68.7 -40.0 35.0 0.152 0.0 HOH
 2.819
 O
 O
TYR B:166 B:166 34.0 0.148 H -67.5 -37.7 34.0 0.148 0.0 HOH
 2.674
 O
 O
6yaw 1 P08263 90.54 6e-146 X-RAY
 2020-08-26 TYR A:166 A:166 30.0 0.13 H -67.3 -34.6 30.0 0.13 0.0 HOH
 2.976
 OH
 O
TYR B:166 B:166 32.0 0.139 H -72.3 -26.8 32.0 0.139 0.0 HOH
 3.036
 OH
 O
2r6k 1 P08263 90.09 9e-146 X-RAY
 2008-08-19 TYR A:166 A:166 33.0 0.143 H -73.9 -34.2 33.0 0.143 0.0 HOH
 2.905
 OH
 O
TYR B:166 B:166 28.0 0.122 H -76.9 -34.9 28.0 0.122 0.0 HOH
 2.865
 OH
 O
3zfl 1 P08263 90.09 3e-145 X-RAY
 2012-12-19 TYR A:166 A:166 40.0 0.174 H -72.0 -35.8 40.0 0.174 0.0 HOH
 2.847
 OH
 O
TYR B:166 B:166 35.0 0.152 H -72.0 -36.7 35.0 0.152 0.0 HOH
 2.796
 OH
 O
3zfb 1 P08263 90.09 3e-145 X-RAY
 2012-12-19 TYR A:166 A:166 36.0 0.157 H -74.0 -34.3 36.0 0.157 0.0 HOH
 3.351
 CD2
 O
TYR B:166 B:166 38.0 0.165 H -68.5 -37.5 38.0 0.165 0.0 HOH
 2.796
 OH
 O
1ydk 1 P08263 90.09 3e-145 X-RAY
 2005-06-07 TYR A:166 A:166 33.0 0.143 H -72.9 -40.8 33.0 0.143 0.0 HOH
 2.805
 OH
 O
TYR B:166 B:166 34.0 0.148 H -69.6 -42.2 34.0 0.148 0.0 HOH
 2.695
 O
 O
3u6v 1 P08263 90.09 3e-145 X-RAY
 2011-10-26 TYR A:166 A:166 40.0 0.174 H -69.6 -36.4 40.0 0.174 0.0 HOH
 2.887
 OH
 O
TYR B:166 B:166 36.0 0.157 H -65.7 -33.1 36.0 0.157 0.0 HOH
 2.911
 OH
 O
1pl2 1 P08263 90.09 5e-145 X-RAY
 2004-06-22 TYR A:166 A:166 35.0 0.152 H -67.0 -38.9 35.0 0.152 0.0 HOH
 2.783
 O
 O
TYR B:166 B:166 36.0 0.157 H -66.7 -40.5 36.0 0.157 0.0 HOH
 2.718
 O
 O
1gsd 1 P08263 90.5 6e-145 X-RAY
 1995-09-15 TYR A:165 A:166 31.0 0.135 H -69.0 -37.9 31.0 0.135 0.0 HOH
 2.999
 OH
 O
TYR B:165 B:166 29.0 0.126 H -69.0 -37.9 29.0 0.126 0.0 HOH
 2.999
 OH
 O
TYR C:165 C:166 31.0 0.135 H -69.0 -38.0 NA NA NA
TYR D:165 D:166 29.0 0.126 H -69.1 -37.8 NA NA NA
1gsf 1 P08263 90.5 6e-145 X-RAY
 1995-09-15 TYR A:165 A:166 38.0 0.165 H -58.3 -34.7 38.0 0.165 0.0 HOH
 2.886
 OH
 O
TYR B:165 B:166 37.0 0.161 H -58.3 -34.8 37.0 0.161 0.0 HOH
 2.886
 OH
 O
TYR C:165 C:166 36.0 0.157 H -58.2 -34.8 NA NA NA
TYR D:165 D:166 36.0 0.157 H -58.3 -34.8 NA NA NA
1guh 1 P08263 90.5 6e-145 X-RAY
 1993-10-31 TYR A:165 A:166 33.0 0.143 H -68.8 -26.0 33.0 0.143 0.0
TYR B:165 B:166 34.0 0.148 H -68.8 -26.0 34.0 0.148 0.0
TYR C:165 C:166 35.0 0.152 H -68.8 -26.0 NA NA NA
TYR D:165 D:166 33.0 0.143 H -68.8 -26.0 NA NA NA
1k3l 1 P08263 90.5 6e-145 X-RAY
 2002-10-23 TYR A:165 A:166 33.0 0.143 H -71.4 -34.8 33.0 0.143 0.0 HOH
 2.818
 OH
 O
TYR B:165 B:166 29.0 0.126 H -68.5 -37.4 29.0 0.126 0.0 HOH
 2.772
 OH
 O
1k3o 1 P08263 90.5 6e-145 X-RAY
 2002-10-30 TYR A:165 A:166 49.0 0.213 H -82.6 -43.7 49.0 0.213 0.0 HOH
 2.857
 OH
 O
TYR B:165 B:166 44.0 0.191 H -67.1 -34.9 44.0 0.191 0.0 HOH
 2.905
 OH
 O
1k3y 1 P08263 90.5 6e-145 X-RAY
 2002-10-30 TYR A:165 A:166 35.0 0.152 H -65.1 -40.4 35.0 0.152 0.0 GOL
HOH
 9.932
2.775
 CE2
OH
 O1
O
TYR B:165 B:166 28.0 0.122 H -67.0 -38.2 28.0 0.122 0.0 HOH
 2.795
 OH
 O
6ato 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:165 A:166 35.0 0.152 H -71.9 -38.2 35.0 0.152 0.0 HOH
 2.735
 OH
 O
TYR B:165 B:166 33.0 0.143 H -68.4 -39.2 NA NA NA
6atp 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:165 A:166 38.0 0.165 H -69.9 -37.1 38.0 0.165 0.0 HOH
 2.814
 OH
 O
TYR B:165 B:166 35.0 0.152 H -68.6 -38.6 NA NA NA
6atq 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:165 A:166 37.0 0.161 H -70.1 -35.5 37.0 0.161 0.0 HOH
 2.781
 OH
 O
TYR B:165 B:166 37.0 0.161 H -68.8 -39.3 NA NA NA
6atr 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:165 A:166 33.0 0.143 H -69.3 -37.8 33.0 0.143 0.0 EDO
EDO
EDO
EDO
HOH
 3.128
9.520
5.561
2.636
2.868
 O
CE2
CE2
CG
OH
 H12
O1
H21
H11
O
TYR B:165 B:166 32.0 0.139 H -71.0 -36.5 NA NA NA
2r3x 1 P08263 90.09 8e-145 X-RAY
 2007-12-18 TYR A:166 A:166 37.0 0.161 H -65.8 -44.2 37.0 0.161 0.0 HOH
 2.664
 OH
 O
TYR B:166 B:166 29.0 0.126 H -68.7 -41.3 29.0 0.126 0.0 HOH
 2.904
 O
 O
1gse 1 P08263 90.05 2e-144 X-RAY
 1995-09-15 TYR A:165 A:166 37.0 0.161 H -70.4 -38.5 37.0 0.161 0.0 EAA
BME
HOH
 7.167
7.679
3.030
 CE1
CE2
OH
 OXT
C2
O
TYR B:165 B:166 37.0 0.161 H -70.4 -36.1 37.0 0.161 0.0 EAA
BME
HOH
 7.110
7.654
2.890
 CE1
CE2
OH
 OXT
C2
O
1usb 1 P08263 90.05 2e-144 X-RAY
 2004-09-01 TYR A:169 A:166 39.0 0.17 H -64.5 -35.2 39.0 0.17 0.0 HOH
 2.763
 OH
 O
TYR B:169 B:166 40.0 0.174 H -64.9 -40.7 40.0 0.174 0.0 HOH
 2.711
 O
 O
3l0h 1 P08263 90.09 2e-144 X-RAY
 2010-01-12 TYR A:166 A:166 39.0 0.17 H -69.5 -31.6 39.0 0.17 0.0 HOH
 2.872
 OH
 O
TYR B:166 B:166 38.0 0.165 H -58.6 -37.7 38.0 0.165 0.0 HOH
 2.680
 O
 O
3q74 1 P08263 90.05 3e-144 X-RAY
 2011-01-12 TYR A:165 A:166 38.0 0.165 H -64.8 -41.3 38.0 0.165 0.0 HOH
 2.792
 O
 O
TYR B:165 B:166 36.0 0.157 H -65.8 -42.0 36.0 0.157 0.0 HOH
 2.524
 O
 O
3ktl 1 P08263 90.05 3e-144 X-RAY
 2009-12-22 TYR A:165 A:166 35.0 0.152 H -72.2 -34.9 35.0 0.152 0.0 HOH
 2.717
 O
 O
TYR B:165 B:166 28.0 0.122 H -70.3 -37.7 28.0 0.122 0.0 HOH
 2.768
 OH
 O
1xwg 1 P08263 90.05 5e-144 X-RAY
 2005-11-01 TYR A:165 A:166 39.0 0.17 H -64.5 -41.8 39.0 0.17 0.0 HOH
 2.888
 OH
 O
TYR B:165 B:166 35.0 0.152 H -71.0 -36.6 35.0 0.152 0.0 HOH
 2.714
 O
 O
5jcu 1 P08263 90.05 2e-143 X-RAY
 2016-10-12 TYR A:165 A:166 32.0 0.139 H -71.5 -34.7 32.0 0.139 0.0 EDO
EDO
EDO
HOH
 3.437
6.696
9.671
2.959
 O
CE2
CE2
OH
 C2
C1
O2
O
TYR B:165 B:166 32.0 0.139 H -75.4 -32.2 32.0 0.139 0.0 HOH
 3.013
 OH
 O
TYR C:165 C:166 34.0 0.148 H -64.0 -38.1 NA NA NA
TYR D:165 D:166 33.0 0.143 H -71.7 -38.2 NA NA NA
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 TYR A:166 A:166 27.0 0.117 H -73.6 -37.7 27.0 0.117 0.0 HOH
 2.876
 OH
 O
TYR B:166 B:166 30.0 0.13 H -75.3 -41.0 30.0 0.13 0.0 HOH
 2.984
 OH
 O
TYR C:166 C:166 29.0 0.126 H -72.6 -44.5 NA NA NA
TYR D:166 D:166 26.0 0.113 H -74.1 -37.5 NA NA NA
TYR E:166 E:166 28.0 0.122 H -74.7 -45.3 NA NA NA
TYR F:166 F:166 23.0 0.1 H -75.4 -35.5 NA NA NA
TYR G:166 G:166 27.0 0.117 H -65.3 -38.3 NA NA NA
TYR H:166 H:166 28.0 0.122 H -76.1 -44.0 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 TYR A:166 A:166 27.0 0.117 H -74.8 -34.7 27.0 0.117 0.0 HOH
 2.967
 OH
 O
TYR B:166 B:166 27.0 0.117 H -76.9 -29.7 27.0 0.117 0.0 HOH
 3.033
 OH
 O
TYR C:166 C:166 25.0 0.109 H -70.0 -32.8 NA NA NA
TYR D:166 D:166 26.0 0.113 H -72.6 -37.8 NA NA NA
TYR E:166 E:166 29.0 0.126 H -70.7 -38.0 NA NA NA
TYR F:166 F:166 25.0 0.109 H -80.4 -31.7 NA NA NA
TYR G:166 G:166 23.0 0.1 H -74.8 -31.6 NA NA NA
TYR H:166 H:166 26.0 0.113 H -72.5 -30.7 NA NA NA
4hj2 1 P08263 90.78 5e-143 X-RAY
 2013-03-27 TYR A:163 A:166 31.0 0.135 H -71.8 -33.4 31.0 0.135 0.0 LZ6
HOH
 7.719
2.913
 CE2
OH
 O18
O
TYR B:163 B:166 43.0 0.187 H -62.1 -42.2 43.0 0.187 0.0 LZ6
HOH
 7.446
3.118
 CD2
OH
 O18
O
4acs 1 P09210 87.33 9e-139 X-RAY
 2011-12-28 TYR A:166 A:166 30.0 0.13 H -72.7 -36.0 30.0 0.13 0.0 HOH
 3.044
 OH
 O
TYR B:166 B:166 31.0 0.135 H -78.4 -36.4 31.0 0.135 0.0 HOH
 2.801
 OH
 O
TYR C:166 C:166 27.0 0.117 H -79.9 -35.3 NA NA NA
TYR D:166 D:166 25.0 0.109 H -78.7 -39.7 NA NA NA
3i69 1 P08263 86.88 9e-139 X-RAY
 2009-09-01 TYR A:166 A:166 25.0 0.109 H -76.1 -33.1 25.0 0.109 0.0 HOH
 3.262
 OH
 O
TYR B:166 B:166 26.0 0.113 H -71.8 -34.8 26.0 0.113 0.0 HOH
 3.753
 CE2
 O
TYR C:166 C:166 26.0 0.113 H -69.6 -36.7 NA NA NA
TYR D:166 D:166 45.0 0.196 H -65.4 -37.6 NA NA NA
TYR E:166 E:166 26.0 0.113 H -75.2 -33.9 NA NA NA
TYR F:166 F:166 41.0 0.178 H -65.1 -39.4 NA NA NA
TYR G:166 G:166 30.0 0.13 H -70.0 -42.8 NA NA NA
TYR H:166 H:166 25.0 0.109 H -75.4 -35.3 NA NA NA
3i6a 1 P08263 86.88 9e-139 X-RAY
 2009-09-01 TYR A:166 A:166 29.0 0.126 H -70.8 -38.6 29.0 0.126 0.0 HOH
 3.820
 OH
 O
TYR B:166 B:166 42.0 0.183 H -67.3 -42.5 42.0 0.183 0.0 HOH
 3.547
 N
 O
TYR C:166 C:166 30.0 0.13 H -65.2 -37.6 NA NA NA
TYR D:166 D:166 44.0 0.191 H -59.8 -40.0 NA NA NA
TYR E:166 E:166 29.0 0.126 H -71.2 -38.6 NA NA NA
TYR F:166 F:166 38.0 0.165 H -65.6 -38.5 NA NA NA
TYR G:166 G:166 35.0 0.152 H -69.6 -37.2 NA NA NA
TYR H:166 H:166 27.0 0.117 H -78.7 -35.2 NA NA NA
3ik9 1 P08263 86.88 9e-139 X-RAY
 2010-06-23 TYR A:166 A:166 23.0 0.1 H -63.9 -32.9 23.0 0.1 0.0 HOH
 5.817
 OH
 O
TYR B:166 B:166 28.0 0.122 H -73.1 -37.6 28.0 0.122 0.0 HOH
 3.097
 OH
 O
TYR C:166 C:166 27.0 0.117 H -63.3 -34.2 NA NA NA
TYR D:166 D:166 38.0 0.165 H -58.1 -36.4 NA NA NA
TYR E:166 E:166 33.0 0.143 H -88.1 -29.5 NA NA NA
TYR F:166 F:166 37.0 0.161 H -55.8 -43.4 NA NA NA
TYR G:166 G:166 31.0 0.135 H -72.7 -34.3 NA NA NA
TYR H:166 H:166 31.0 0.135 H -68.7 -33.2 NA NA NA
6zj9 1 M9ZT87 80.63 1e-132 X-RAY
 2020-11-18 LEU A:166 A:166 24.0 0.141 H -67.5 -39.9 24.0 0.141 0.0 EDO
HOH
 7.811
2.802
 CD1
O
 O2
O
6zjc 1 M9ZT87 80.63 1e-132 X-RAY
 2020-11-18 LEU A:166 B:166 24.0 0.141 H -63.1 -46.7 24.0 0.141 0.0 MPD
HOH
 9.536
3.125
 CD2
O
 C1
O
LEU B:166 A:166 22.0 0.129 H -64.7 -45.8 22.0 0.129 0.0 MPD
HOH
 8.954
3.541
 CD2
CD2
 O2
O
LEU C:166 D:166 23.0 0.135 H -65.6 -45.4 NA NA NA
LEU D:166 C:166 23.0 0.135 H -63.6 -46.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16772-f1 1 Q16772 100.0 4e-164 TYR A:166 A:166 15.0 0.065 H -65.8 -38.6
af-p08263-f1 1 P08263 90.54 2e-146 TYR A:166 A:166 33.0 0.143 H -63.3 -39.5
af-p09210-f1 1 P09210 88.74 2e-143 TYR A:166 A:166 32.0 0.139 H -64.3 -40.9
af-q7rtv2-f1 1 Q7RTV2 85.59 7e-139 TYR A:166 A:166 14.0 0.061 H -64.5 -41.7