Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52762730 . A C CCDS4947.1:NM_000847.4:c.439Tac>Gac_NP_000838.3:p.147Y>D Homo sapiens glutathione S-transferase alpha 3 (GSTA3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1tdi 1 Q16772 100.0 9e-164 X-RAY
 2005-01-18 TYR A:147 A:147 48.0 0.209 S -119.8 156.3 48.0 0.209 0.0 HOH
 2.643
 O
 O
TYR B:147 B:147 65.0 0.283 S -122.2 152.7 65.0 0.283 0.0 HOH
 2.734
 O
 O
2vcv 1 Q16772 100.0 9e-164 X-RAY
 2008-10-28 TYR A:147 A:147 42.0 0.183 S -128.2 153.0 42.0 0.183 0.0 HOH
 2.672
 O
 O
TYR B:147 B:147 56.0 0.243 S -126.3 149.6 56.0 0.243 0.0 HOH
 2.455
 OH
 O
TYR C:147 C:147 73.0 0.317 S -129.3 153.4 NA NA NA
TYR D:147 D:147 44.0 0.191 S -116.8 152.9 NA NA NA
TYR E:147 E:147 56.0 0.243 S -123.2 152.2 NA NA NA
TYR F:147 F:147 43.0 0.187 S -122.7 157.8 NA NA NA
TYR G:147 G:147 46.0 0.2 S -126.5 153.9 NA NA NA
TYR H:147 H:147 62.0 0.27 S -121.0 152.4 NA NA NA
TYR I:147 I:147 49.0 0.213 S -123.6 158.5 NA NA NA
TYR J:147 J:147 72.0 0.313 S -129.2 148.2 NA NA NA
TYR K:147 K:147 45.0 0.196 S -133.3 157.4 NA NA NA
TYR L:147 L:147 52.0 0.226 S -123.4 157.0 NA NA NA
TYR M:147 M:147 47.0 0.204 S -125.3 159.5 NA NA NA
TYR N:147 N:147 66.0 0.287 S -127.0 152.4 NA NA NA
TYR O:147 O:147 48.0 0.209 S -128.2 151.1 NA NA NA
TYR P:147 P:147 60.0 0.261 S -120.1 152.5 NA NA NA
1pkw 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 TYR A:147 A:147 55.0 0.239 S -124.1 151.9 55.0 0.239 0.0 HOH
 2.664
 OH
 O
TYR B:147 B:147 55.0 0.239 S -128.2 151.3 55.0 0.239 0.0 HOH
 2.549
 O
 O
1pkz 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 TYR A:147 A:147 52.0 0.226 S -123.9 150.0 52.0 0.226 0.0 HOH
 2.666
 OH
 O
TYR B:147 B:147 52.0 0.226 S -122.7 157.4 52.0 0.226 0.0 HOH
 2.699
 OH
 O
1pl1 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 TYR A:147 A:147 53.0 0.23 S -120.8 152.6 53.0 0.23 0.0 HOH
 2.471
 OH
 O
TYR B:147 B:147 55.0 0.239 S -123.3 158.2 55.0 0.239 0.0 HOH
 2.738
 O
 O
6yaw 1 P08263 90.54 6e-146 X-RAY
 2020-08-26 TYR A:147 A:147 53.0 0.23 S -124.1 153.2 53.0 0.23 0.0 HOH
 2.379
 O
 O
TYR B:147 B:147 51.0 0.222 S -127.5 156.9 51.0 0.222 0.0 HOH
 2.743
 O
 O
2r6k 1 P08263 90.09 9e-146 X-RAY
 2008-08-19 TYR A:147 A:147 48.0 0.209 S -118.4 160.9 48.0 0.209 0.0 HOH
 2.544
 O
 O
TYR B:147 B:147 48.0 0.209 S -119.2 163.0 48.0 0.209 0.0 HOH
 2.612
 O
 O
3zfl 1 P08263 90.09 3e-145 X-RAY
 2012-12-19 TYR A:147 A:147 55.0 0.239 S -117.0 158.7 55.0 0.239 0.0 HOH
 2.552
 OH
 O
TYR B:147 B:147 51.0 0.222 S -124.3 150.6 51.0 0.222 0.0 HOH
 2.433
 OH
 O
3zfb 1 P08263 90.09 3e-145 X-RAY
 2012-12-19 TYR A:147 A:147 53.0 0.23 S -129.8 153.2 53.0 0.23 0.0 HOH
 2.702
 OH
 O
TYR B:147 B:147 53.0 0.23 S -131.9 146.8 53.0 0.23 0.0 HOH
 2.637
 O
 O
1ydk 1 P08263 90.09 3e-145 X-RAY
 2005-06-07 TYR A:147 A:147 54.0 0.235 S -124.6 153.8 54.0 0.235 0.0 HOH
 2.677
 OH
 O
TYR B:147 B:147 52.0 0.226 S -129.5 151.5 52.0 0.226 0.0 HOH
 2.637
 O
 O
3u6v 1 P08263 90.09 3e-145 X-RAY
 2011-10-26 TYR A:147 A:147 51.0 0.222 S -117.5 159.4 51.0 0.222 0.0 HOH
 2.585
 O
 O
TYR B:147 B:147 54.0 0.235 S -119.7 154.0 54.0 0.235 0.0 HOH
 2.635
 O
 O
1pl2 1 P08263 90.09 5e-145 X-RAY
 2004-06-22 TYR A:147 A:147 53.0 0.23 S -120.0 156.5 53.0 0.23 0.0 HOH
 2.540
 OH
 O
TYR B:147 B:147 53.0 0.23 S -124.6 155.2 53.0 0.23 0.0 HOH
 2.717
 O
 O
1gsd 1 P08263 90.5 6e-145 X-RAY
 1995-09-15 TYR A:146 A:147 49.0 0.213 S -114.4 158.3 49.0 0.213 0.0 HOH
 2.806
 O
 O
TYR B:146 B:147 48.0 0.209 S -114.4 158.3 48.0 0.209 0.0 HOH
 2.805
 O
 O
TYR C:146 C:147 47.0 0.204 S -114.4 158.3 NA NA NA
TYR D:146 D:147 47.0 0.204 S -114.4 158.3 NA NA NA
1gsf 1 P08263 90.5 6e-145 X-RAY
 1995-09-15 TYR A:146 A:147 49.0 0.213 S -126.0 159.7 49.0 0.213 0.0 HOH
 2.663
 OH
 O
TYR B:146 B:147 49.0 0.213 S -126.0 159.8 49.0 0.213 0.0 HOH
 2.663
 OH
 O
TYR C:146 C:147 49.0 0.213 S -126.0 159.7 NA NA NA
TYR D:146 D:147 48.0 0.209 S -126.0 159.7 NA NA NA
1guh 1 P08263 90.5 6e-145 X-RAY
 1993-10-31 TYR A:146 A:147 44.0 0.191 S -120.7 155.7 44.0 0.191 0.0
TYR B:146 B:147 44.0 0.191 S -120.7 155.7 44.0 0.191 0.0
TYR C:146 C:147 45.0 0.196 S -120.7 155.7 NA NA NA
TYR D:146 D:147 44.0 0.191 S -120.8 155.7 NA NA NA
1k3l 1 P08263 90.5 6e-145 X-RAY
 2002-10-23 TYR A:146 A:147 52.0 0.226 S -124.4 156.2 52.0 0.226 0.0 HOH
 2.465
 OH
 O
TYR B:146 B:147 45.0 0.196 S -125.6 150.9 45.0 0.196 0.0 HOH
 2.515
 OH
 O
1k3o 1 P08263 90.5 6e-145 X-RAY
 2002-10-30 TYR A:146 A:147 56.0 0.243 S -123.2 160.9 56.0 0.243 0.0 HOH
 2.675
 OH
 O
TYR B:146 B:147 56.0 0.243 S -116.4 163.9 56.0 0.243 0.0 HOH
 2.633
 O
 O
1k3y 1 P08263 90.5 6e-145 X-RAY
 2002-10-30 TYR A:146 A:147 54.0 0.235 S -125.9 154.0 54.0 0.235 0.0 HOH
 2.524
 OH
 O
TYR B:146 B:147 47.0 0.204 S -121.7 160.3 47.0 0.204 0.0 HOH
 2.759
 O
 O
6ato 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:146 A:147 56.0 0.243 S -131.1 154.7 56.0 0.243 0.0 HOH
 2.734
 OH
 O
TYR B:146 B:147 73.0 0.317 S -128.1 154.3 NA NA NA
6atp 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:146 A:147 55.0 0.239 S -127.9 153.7 55.0 0.239 0.0 HOH
 2.663
 OH
 O
TYR B:146 B:147 54.0 0.235 S -126.9 156.7 NA NA NA
6atq 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:146 A:147 58.0 0.252 S -126.2 151.1 58.0 0.252 0.0 HOH
 2.594
 O
 O
TYR B:146 B:147 55.0 0.239 S -128.6 151.1 NA NA NA
6atr 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 TYR A:146 A:147 55.0 0.239 S -129.1 159.5 55.0 0.239 0.0 HOH
 2.359
 OH
 O
TYR B:146 B:147 53.0 0.23 S -128.0 160.9 NA NA NA
2r3x 1 P08263 90.09 8e-145 X-RAY
 2007-12-18 TYR A:147 A:147 57.0 0.248 S -124.7 155.8 57.0 0.248 0.0 HOH
 2.466
 OH
 O
TYR B:147 B:147 53.0 0.23 S -123.1 157.9 53.0 0.23 0.0 HOH
 2.505
 OH
 O
1gse 1 P08263 90.05 2e-144 X-RAY
 1995-09-15 TYR A:146 A:147 47.0 0.204 S -120.9 158.9 47.0 0.204 0.0 HOH
 2.720
 O
 O
TYR B:146 B:147 50.0 0.217 S -122.7 157.1 50.0 0.217 0.0 HOH
 2.826
 O
 O
1usb 1 P08263 90.05 2e-144 X-RAY
 2004-09-01 TYR A:150 A:147 45.0 0.196 S -124.9 156.8 45.0 0.196 0.0 K
HOH
 3.784
2.388
 CB
OH
 K
O
TYR B:150 B:147 52.0 0.226 S -122.8 155.2 52.0 0.226 0.0 K
HOH
 3.702
2.684
 CB
O
 K
O
3l0h 1 P08263 90.09 2e-144 X-RAY
 2010-01-12 TYR A:147 A:147 50.0 0.217 S -119.2 157.1 50.0 0.217 0.0 HOH
 2.496
 O
 O
TYR B:147 B:147 50.0 0.217 S -118.7 153.7 50.0 0.217 0.0 HOH
 2.721
 O
 O
3q74 1 P08263 90.05 3e-144 X-RAY
 2011-01-12 TYR A:146 A:147 54.0 0.235 S -124.9 153.1 54.0 0.235 0.0 HOH
 2.641
 OH
 O
TYR B:146 B:147 50.0 0.217 S -125.1 158.3 50.0 0.217 0.0 HOH
 2.614
 OH
 O
3ktl 1 P08263 90.05 3e-144 X-RAY
 2009-12-22 TYR A:146 A:147 54.0 0.235 S -123.5 158.0 54.0 0.235 0.0 HOH
 2.671
 OH
 O
TYR B:146 B:147 49.0 0.213 S -119.9 154.9 49.0 0.213 0.0 HOH
 2.605
 OH
 O
1xwg 1 P08263 90.05 5e-144 X-RAY
 2005-11-01 TYR A:146 A:147 53.0 0.23 S -121.4 155.4 53.0 0.23 0.0 HOH
 2.593
 OH
 O
TYR B:146 B:147 55.0 0.239 S -119.5 157.4 55.0 0.239 0.0 HOH
 2.657
 OH
 O
5jcu 1 P08263 90.05 2e-143 X-RAY
 2016-10-12 TYR A:146 A:147 54.0 0.235 S -124.5 158.8 54.0 0.235 0.0 HOH
 2.374
 OH
 O
TYR B:146 B:147 53.0 0.23 S -124.8 160.3 53.0 0.23 0.0 HOH
 2.947
 O
 O
TYR C:146 C:147 57.0 0.248 S -126.5 156.7 NA NA NA
TYR D:146 D:147 53.0 0.23 S -121.1 151.3 NA NA NA
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 TYR A:147 A:147 60.0 0.261 S -126.3 154.6 60.0 0.261 0.0 HOH
 2.260
 O
 O
TYR B:147 B:147 56.0 0.243 S -118.3 159.5 56.0 0.243 0.0 HOH
 2.687
 OH
 O
TYR C:147 C:147 51.0 0.222 S -124.9 157.2 NA NA NA
TYR D:147 D:147 56.0 0.243 S -131.2 152.8 NA NA NA
TYR E:147 E:147 67.0 0.291 S -112.2 149.4 NA NA NA
TYR F:147 F:147 42.0 0.183 S -128.9 155.2 NA NA NA
TYR G:147 G:147 46.0 0.2 S -127.5 153.2 NA NA NA
TYR H:147 H:147 53.0 0.23 S -116.5 162.1 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 TYR A:147 A:147 47.0 0.204 S -127.0 156.6 47.0 0.204 0.0 HOH
 3.000
 OH
 O
TYR B:147 B:147 45.0 0.196 S -135.0 161.0 45.0 0.196 0.0 HOH
 3.627
 CB
 O
TYR C:147 C:147 53.0 0.23 S -119.3 165.4 NA NA NA
TYR D:147 D:147 49.0 0.213 S -112.7 152.1 NA NA NA
TYR E:147 E:147 46.0 0.2 S -137.1 159.8 NA NA NA
TYR F:147 F:147 57.0 0.248 S -129.7 154.8 NA NA NA
TYR G:147 G:147 61.0 0.265 S -112.1 163.2 NA NA NA
TYR H:147 H:147 35.0 0.152 S -130.2 168.6 NA NA NA
4hj2 1 P08263 90.78 5e-143 X-RAY
 2013-03-27 TYR A:144 A:147 53.0 0.23 S -128.2 162.3 53.0 0.23 0.0 HOH
 2.854
 O
 O
TYR B:144 B:147 57.0 0.248 S -120.1 157.6 57.0 0.248 0.0 HOH
 2.653
 O
 O
4acs 1 P09210 87.33 9e-139 X-RAY
 2011-12-28 TYR A:147 A:147 56.0 0.243 S -127.2 169.3 56.0 0.243 0.0 HOH
 2.444
 O
 O
TYR B:147 B:147 58.0 0.252 S -131.0 164.8 58.0 0.252 0.0 HOH
 2.465
 OH
 O
TYR C:147 C:147 53.0 0.23 S -123.0 169.6 NA NA NA
TYR D:147 D:147 45.0 0.196 S -136.4 146.5 NA NA NA
3i69 1 P08263 86.88 9e-139 X-RAY
 2009-09-01 TYR A:147 A:147 57.0 0.248 S -132.4 152.2 57.0 0.248 0.0 HOH
 2.563
 O
 O
TYR B:147 B:147 52.0 0.226 S -120.1 156.6 52.0 0.226 0.0 HOH
 2.614
 O
 O
TYR C:147 C:147 49.0 0.213 S -137.7 155.6 NA NA NA
TYR D:147 D:147 47.0 0.204 S -127.3 152.1 NA NA NA
TYR E:147 E:147 43.0 0.187 S -119.0 172.2 NA NA NA
TYR F:147 F:147 34.0 0.148 S -135.1 160.4 NA NA NA
TYR G:147 G:147 40.0 0.174 S -127.8 152.8 NA NA NA
TYR H:147 H:147 53.0 0.23 S -126.6 171.0 NA NA NA
3i6a 1 P08263 86.88 9e-139 X-RAY
 2009-09-01 TYR A:147 A:147 57.0 0.248 S -128.2 149.9 57.0 0.248 0.0 HOH
 2.699
 O
 O
TYR B:147 B:147 49.0 0.213 S -121.5 156.8 49.0 0.213 0.0 HOH
 2.924
 OH
 O
TYR C:147 C:147 53.0 0.23 S -127.5 156.7 NA NA NA
TYR D:147 D:147 48.0 0.209 S -128.9 151.3 NA NA NA
TYR E:147 E:147 48.0 0.209 S -122.8 158.2 NA NA NA
TYR F:147 F:147 36.0 0.157 S -134.4 161.0 NA NA NA
TYR G:147 G:147 46.0 0.2 S -134.7 158.9 NA NA NA
TYR H:147 H:147 53.0 0.23 S -122.2 155.6 NA NA NA
3ik9 1 P08263 86.88 9e-139 X-RAY
 2010-06-23 TYR A:147 A:147 53.0 0.23 S -122.2 161.3 53.0 0.23 0.0
TYR B:147 B:147 48.0 0.209 S -115.5 148.4 48.0 0.209 0.0 HOH
 3.867
 CB
 O
TYR C:147 C:147 57.0 0.248 S -136.7 150.1 NA NA NA
TYR D:147 D:147 47.0 0.204 S -122.4 150.1 NA NA NA
TYR E:147 E:147 51.0 0.222 S -130.2 160.4 NA NA NA
TYR F:147 F:147 41.0 0.178 S -127.6 170.6 NA NA NA
TYR G:147 G:147 45.0 0.196 S -124.5 157.7 NA NA NA
TYR H:147 H:147 48.0 0.209 S -131.9 165.2 NA NA NA
6zj9 1 M9ZT87 80.63 1e-132 X-RAY
 2020-11-18 TYR A:147 A:147 58.0 0.252 S -125.7 152.0 58.0 0.252 0.0 HOH
 2.649
 OH
 O
6zjc 1 M9ZT87 80.63 1e-132 X-RAY
 2020-11-18 TYR A:147 B:147 57.0 0.248 S -125.4 153.1 57.0 0.248 0.0 HOH
 2.703
 O
 O
TYR B:147 A:147 57.0 0.248 S -125.7 153.0 57.0 0.248 0.0 HOH
 2.507
 OH
 O
TYR C:147 D:147 56.0 0.243 S -126.3 153.3 NA NA NA
TYR D:147 C:147 58.0 0.252 S -124.9 151.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16772-f1 1 Q16772 100.0 4e-164 TYR A:147 A:147 45.0 0.196 S -132.5 156.5
af-p08263-f1 1 P08263 90.54 2e-146 TYR A:147 A:147 44.0 0.191 S -127.9 155.9
af-p09210-f1 1 P09210 88.74 2e-143 TYR A:147 A:147 43.0 0.187 S -132.0 155.7
af-q7rtv2-f1 1 Q7RTV2 85.59 7e-139 TYR A:147 A:147 45.0 0.196 S -132.5 157.0