Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr6 52764813 . T A CCDS4947.1:NM_000847.4:c.333ttA>ttT_NP_000838.3:p.111L>F Homo sapiens glutathione S-transferase alpha 3 (GSTA3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1tdi 1 Q16772 100.0 9e-164 X-RAY
 2005-01-18 LEU A:111 A:111 104.0 0.612 G -100.7 -14.6 104.0 0.612 0.0 GSH
HOH
 9.232
4.515
 CD1
C
 SG2
O
LEU B:111 B:111 129.0 0.759 G -68.9 -15.2 129.0 0.759 0.0 GSH
HOH
 8.865
8.262
 CD1
CD1
 SG2
O
2vcv 1 Q16772 100.0 9e-164 X-RAY
 2008-10-28 LEU A:111 A:111 78.0 0.459 G -82.7 -11.8 78.0 0.459 0.0 GSH
ASD
HOH
 9.793
4.006
4.448
 CD1
CD2
CB
 SG2
C12
O
LEU B:111 B:111 77.0 0.453 G -79.7 -16.7 77.0 0.453 0.0 GSH
ASD
HOH
 9.349
4.132
2.816
 CD1
CD1
O
 SG2
C1
O
LEU C:111 C:111 82.0 0.482 G -72.8 -20.3 NA NA NA
LEU D:111 D:111 85.0 0.5 G -86.4 -16.8 NA NA NA
LEU E:111 E:111 77.0 0.453 G -86.1 -8.0 NA NA NA
LEU F:111 F:111 76.0 0.447 G -88.8 -10.3 NA NA NA
LEU G:111 G:111 82.0 0.482 G -93.0 -11.1 NA NA NA
LEU H:111 H:111 81.0 0.476 G -80.1 -12.7 NA NA NA
LEU I:111 I:111 80.0 0.471 G -84.7 -18.3 NA NA NA
LEU J:111 J:111 81.0 0.476 G -90.3 5.8 NA NA NA
LEU K:111 K:111 74.0 0.435 G -87.1 -16.0 NA NA NA
LEU L:111 L:111 80.0 0.471 G -85.1 -9.4 NA NA NA
LEU M:111 M:111 75.0 0.441 G -81.8 -7.5 NA NA NA
LEU N:111 N:111 76.0 0.447 G -94.8 -15.2 NA NA NA
LEU O:111 O:111 90.0 0.529 G -77.9 -9.7 NA NA NA
LEU P:111 P:111 73.0 0.429 G -79.1 -27.2 NA NA NA
1pkw 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 VAL A:111 A:111 89.0 0.574 G -83.4 -33.1 89.0 0.574 0.0 GSH
HOH
 9.405
6.553
 CG2
N
 SG2
O
VAL B:111 B:111 68.0 0.439 G -99.1 0.1 68.0 0.439 0.0 GSH
HOH
 9.963
4.239
 CG1
CG1
 SG2
O
1pkz 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 VAL A:111 A:111 106.0 0.684 G -120.2 -8.4 106.0 0.684 0.0 HOH
 6.305
 N
 O
VAL B:111 B:111 64.0 0.413 G -94.0 -7.4 64.0 0.413 0.0 HOH
 6.789
 N
 O
1pl1 1 P08263 90.54 6e-146 X-RAY
 2004-06-22 VAL A:111 A:111 63.0 0.406 G -93.9 -9.5 63.0 0.406 0.0 ABY
HOH
 4.329
4.129
 CG2
CG1
 C7'
O
VAL B:111 B:111 56.0 0.361 G -100.2 -0.5 56.0 0.361 0.0 ABY
HOH
 4.495
3.574
 CG1
CA
 C7'
O
6yaw 1 P08263 90.54 6e-146 X-RAY
 2020-08-26 VAL A:111 A:111 64.0 0.413 T -112.8 28.9 64.0 0.413 0.0 P9H
HOH
 4.740
4.228
 CG1
CG1
 C5
O
VAL B:111 B:111 70.0 0.452 T -93.9 2.1 70.0 0.452 0.0 P9H
HOH
 4.187
9.738
 CG1
CG2
 C5
O
2r6k 1 P08263 90.09 9e-146 X-RAY
 2008-08-19 VAL A:111 A:111 64.0 0.413 G -90.5 -20.6 64.0 0.413 0.0 GTX
HOH
 3.066
7.235
 CG2
C
 C6S
O
VAL B:111 B:111 64.0 0.413 T -86.8 -33.0 64.0 0.413 0.0 GTX
HOH
 4.317
3.077
 CG2
O
 C5S
O
3zfl 1 P08263 90.09 3e-145 X-RAY
 2012-12-19 VAL A:111 A:111 131.0 0.845 G -108.2 28.8 131.0 0.845 0.0 HOH
 4.310
 O
 O
VAL B:111 B:111 116.0 0.748 T -94.0 11.2 116.0 0.748 0.0 HOH
 3.241
 O
 O
3zfb 1 P08263 90.09 3e-145 X-RAY
 2012-12-19 VAL A:111 A:111 117.0 0.755 G -78.9 17.7 117.0 0.755 0.0 HOH
 6.320
 O
 O
VAL B:111 B:111 121.0 0.781 G -93.6 6.6 121.0 0.781 0.0 HOH
 5.016
 C
 O
1ydk 1 P08263 90.09 3e-145 X-RAY
 2005-06-07 VAL A:111 A:111 114.0 0.735 G -93.4 -13.7 114.0 0.735 0.0 GTX
HOH
 4.284
6.481
 CG2
N
 C6S
O
VAL B:111 B:111 70.0 0.452 G -111.7 7.6 70.0 0.452 0.0 GTX
HOH
 3.810
6.500
 CG1
N
 C6S
O
3u6v 1 P08263 90.09 3e-145 X-RAY
 2011-10-26 VAL A:111 A:111 123.0 0.794 G -86.6 22.8 123.0 0.794 0.0 HOH
 6.698
 C
 O
VAL B:111 B:111 127.0 0.819 T -105.2 9.1 127.0 0.819 0.0 HOH
 3.825
 C
 O
1pl2 1 P08263 90.09 5e-145 X-RAY
 2004-06-22 VAL A:111 A:111 59.0 0.381 G -105.5 -7.5 59.0 0.381 0.0 ABY
HOH
 3.667
6.156
 CG2
CG2
 C7'
O
VAL B:111 B:111 48.0 0.31 G -90.6 -16.3 48.0 0.31 0.0 ABY
HOH
 3.411
6.187
 CG2
CG2
 C7'
O
1gsd 1 P08263 90.5 6e-145 X-RAY
 1995-09-15 VAL A:110 A:111 111.0 0.716 G -87.8 6.3 111.0 0.716 0.0 HOH
 5.016
 CG2
 O
VAL B:110 B:111 110.0 0.71 G -87.8 6.3 110.0 0.71 0.0 HOH
 5.017
 CG2
 O
VAL C:110 C:111 111.0 0.716 G -87.7 6.2 NA NA NA
VAL D:110 D:111 111.0 0.716 G -87.9 6.4 NA NA NA
1gsf 1 P08263 90.5 6e-145 X-RAY
 1995-09-15 VAL A:110 A:111 61.0 0.394 G -94.6 18.9 61.0 0.394 0.0 EAA
HOH
 3.315
8.019
 CG2
CG2
 C9
O
VAL B:110 B:111 59.0 0.381 G -94.6 18.9 59.0 0.381 0.0 EAA
HOH
 3.316
8.019
 CG2
CG2
 C9
O
VAL C:110 C:111 59.0 0.381 G -94.6 18.9 NA NA NA
VAL D:110 D:111 61.0 0.394 G -94.6 18.9 NA NA NA
1guh 1 P08263 90.5 6e-145 X-RAY
 1993-10-31 VAL A:110 A:111 45.0 0.29 G -96.4 -4.6 45.0 0.29 0.0 GSB
 4.760
 CG2
 C4'
VAL B:110 B:111 43.0 0.277 G -96.4 -4.6 43.0 0.277 0.0 GSB
 4.760
 CG2
 C4'
VAL C:110 C:111 42.0 0.271 G -96.4 -4.6 NA NA NA
VAL D:110 D:111 42.0 0.271 G -96.3 -4.6 NA NA NA
1k3l 1 P08263 90.5 6e-145 X-RAY
 2002-10-23 VAL A:110 A:111 60.0 0.387 G -95.6 5.1 60.0 0.387 0.0 GTX
HOH
 3.292
6.020
 CG2
CG2
 C6S
O
VAL B:110 B:111 59.0 0.381 G -96.9 -4.1 59.0 0.381 0.0 GTX
HOH
 4.331
3.823
 CG2
C
 C6S
O
1k3o 1 P08263 90.5 6e-145 X-RAY
 2002-10-30 VAL A:110 NA:NA DO NA DO DO DO NA NA NA
VAL B:110 B:111 111.0 0.716 G -104.1 4.2 111.0 0.716 0.0 HOH
 6.788
 CG2
 O
1k3y 1 P08263 90.5 6e-145 X-RAY
 2002-10-30 VAL A:110 A:111 63.0 0.406 G -98.7 9.6 63.0 0.406 0.0 GTX
HOH
 3.317
5.848
 CG1
CG2
 C6S
O
VAL B:110 B:111 61.0 0.394 G -94.7 0.1 61.0 0.394 0.0 GTX
HOH
 3.434
3.636
 CG1
C
 C6S
O
6ato 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 VAL A:110 A:111 77.0 0.497 G -95.7 10.1 77.0 0.497 0.0 GSH
MPD
HOH
 9.312
2.852
3.997
 CG1
CG1
O
 SG2
H12
O
VAL B:110 B:111 74.0 0.477 G -113.6 12.4 NA NA NA
6atp 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 VAL A:110 A:111 53.0 0.342 G -95.0 15.6 53.0 0.342 0.0 HOH
 4.785
 C
 O
VAL B:110 B:111 64.0 0.413 G -99.4 8.8 NA NA NA
6atq 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 VAL A:110 A:111 45.0 0.29 T -79.7 3.7 45.0 0.29 0.0 MPD
MES
HOH
 4.950
5.088
8.860
 CG1
CG2
N
 HM3
O3S
O
VAL B:110 B:111 68.0 0.439 G -98.1 12.4 NA NA NA
6atr 1 P08263 90.5 6e-145 X-RAY
 2018-09-12 VAL A:110 A:111 77.0 0.497 G -104.4 11.3 77.0 0.497 0.0 GSN
EDO
EDO
HOH
 8.226
9.737
3.948
4.161
 CG2
N
CG1
CG1
 OAV
HO1
O2
O
VAL B:110 B:111 76.0 0.49 G -98.5 0.6 NA NA NA
2r3x 1 P08263 90.09 8e-145 X-RAY
 2007-12-18 VAL A:111 A:111 61.0 0.394 T -100.2 3.0 61.0 0.394 0.0 GTX
HOH
 3.636
3.532
 CG1
CG2
 C6S
O
VAL B:111 B:111 66.0 0.426 T -89.1 -19.0 66.0 0.426 0.0 GTX
HOH
 3.586
3.728
 CG2
O
 C6S
O
1gse 1 P08263 90.05 2e-144 X-RAY
 1995-09-15 VAL A:110 A:111 34.0 0.219 G -102.5 20.5 34.0 0.219 0.0 EAA
HOH
 3.518
3.326
 CG1
O
 CL1
O
VAL B:110 B:111 27.0 0.174 G -90.7 -2.4 27.0 0.174 0.0 GSH
EAA
HOH
 9.732
3.379
6.946
 CG2
CG2
N
 SG2
CL1
O
1usb 1 P08263 90.05 2e-144 X-RAY
 2004-09-01 VAL A:114 A:111 80.0 0.516 T -107.0 17.4 80.0 0.516 0.0 GSH
HOH
 9.832
8.474
 CG2
CG2
 SG2
O
VAL B:114 B:111 74.0 0.477 G -114.8 -8.3 74.0 0.477 0.0 HOH
 6.922
 N
 O
3l0h 1 P08263 90.09 2e-144 X-RAY
 2010-01-12 VAL A:111 A:111 59.0 0.381 G -94.3 17.0 59.0 0.381 0.0 GTX
HOH
 3.599
2.922
 CG1
O
 C6S
O
VAL B:111 B:111 52.0 0.335 G -80.0 14.5 52.0 0.335 0.0 GTX
HOH
 3.823
3.447
 CG1
O
 C6S
O
3q74 1 P08263 90.05 3e-144 X-RAY
 2011-01-12 VAL A:110 A:111 123.0 0.794 G -99.0 7.3 123.0 0.794 0.0 HOH
 5.295
 C
 O
VAL B:110 B:111 120.0 0.774 G -112.3 26.3 120.0 0.774 0.0 HOH
 4.612
 N
 O
3ktl 1 P08263 90.05 3e-144 X-RAY
 2009-12-22 VAL A:110 A:111 57.0 0.368 G -87.7 10.9 57.0 0.368 0.0 GTX
HOH
 3.106
3.234
 CG1
O
 C6S
O
VAL B:110 B:111 57.0 0.368 G -101.8 -0.7 57.0 0.368 0.0 GTX
HOH
 4.475
3.822
 CG2
O
 C5S
O
1xwg 1 P08263 90.05 5e-144 X-RAY
 2005-11-01 VAL A:110 A:111 114.0 0.735 G -88.3 16.4 114.0 0.735 0.0 HOH
 6.667
 N
 O
VAL B:110 B:111 60.0 0.387 G -113.4 11.6 60.0 0.387 0.0 HOH
 6.582
 N
 O
5jcu 1 P08263 90.05 2e-143 X-RAY
 2016-10-12 VAL A:110 A:111 55.0 0.355 G -98.9 14.6 55.0 0.355 0.0 GVX
HOH
 3.149
6.473
 CG1
N
 C29
O
VAL B:110 B:111 57.0 0.368 G -110.9 10.2 57.0 0.368 0.0 GVX
HOH
 3.645
3.381
 CG1
O
 C28
O
VAL C:110 C:111 59.0 0.381 T -76.5 6.3 NA NA NA
VAL D:110 D:111 66.0 0.426 G -129.9 22.7 NA NA NA
2vct 1 P09210 88.74 3e-143 X-RAY
 2008-10-28 PHE A:111 A:111 62.0 0.295 G -96.5 4.9 62.0 0.295 0.0 ASD
HOH
 3.265
3.445
 O
C
 O1
O
PHE B:111 B:111 60.0 0.286 G -95.8 0.5 60.0 0.286 0.0 ASD
HOH
 3.845
3.625
 CZ
C
 C15
O
PHE C:111 C:111 68.0 0.324 G -97.6 -5.8 NA NA NA
PHE D:111 D:111 66.0 0.314 G -95.7 5.2 NA NA NA
PHE E:111 E:111 61.0 0.29 G -91.4 2.0 NA NA NA
PHE F:111 F:111 55.0 0.262 G -83.9 15.0 NA NA NA
PHE G:111 G:111 41.0 0.195 G -95.9 -12.3 NA NA NA
PHE H:111 H:111 45.0 0.214 G -88.1 -9.5 NA NA NA
2wju 1 P09210 88.74 3e-143 X-RAY
 2009-06-09 PHE A:111 A:111 66.0 0.314 T -84.2 -21.6 66.0 0.314 0.0 GSH
HOH
 7.553
7.478
 CZ
CZ
 SG2
O
PHE B:111 B:111 65.0 0.31 G -97.0 -0.7 65.0 0.31 0.0 GSH
HOH
 7.360
6.972
 CZ
CZ
 SG2
O
PHE C:111 C:111 47.0 0.224 G -89.1 7.1 NA NA NA
PHE D:111 D:111 71.0 0.338 G -103.4 1.2 NA NA NA
PHE E:111 E:111 54.0 0.257 G -97.0 -3.5 NA NA NA
PHE F:111 F:111 68.0 0.324 S -93.4 65.4 NA NA NA
PHE G:111 G:111 40.0 0.19 G -87.9 4.1 NA NA NA
PHE H:111 H:111 54.0 0.257 G -108.8 -13.9 NA NA NA
4hj2 1 P08263 90.78 5e-143 X-RAY
 2013-03-27 VAL A:108 A:111 87.0 0.561 T -92.0 -19.8 87.0 0.561 0.0 LZ6
HOH
 3.886
3.327
 CG2
O
 C3
O
VAL B:108 B:111 122.0 0.787 -89.7 360.0 122.0 0.787 0.0 LZ6
HOH
 4.637
5.579
 CG2
N
 C3
O
4acs 1 P09210 87.33 9e-139 X-RAY
 2011-12-28 PHE A:111 A:111 94.0 0.448 H -109.8 -9.4 94.0 0.448 0.0 GSH
HOH
 6.934
3.592
 CZ
CE1
 SG2
O
PHE B:111 B:111 87.0 0.414 H -101.6 -16.6 87.0 0.414 0.0 GSH
HOH
 6.049
6.182
 CZ
CE2
 SG2
O
PHE C:111 C:111 105.0 0.5 T -100.4 3.9 NA NA NA
PHE D:111 D:111 99.0 0.471 T -98.5 7.2 NA NA NA
3i69 1 P08263 86.88 9e-139 X-RAY
 2009-09-01 PHE A:111 A:111 41.0 0.195 G -99.1 -25.6 41.0 0.195 0.0 HOH
 5.230
 CE2
 O
PHE B:111 B:111 51.0 0.243 G -108.2 9.3 51.0 0.243 0.0 GSH
HOH
 6.807
6.663
 CE1
CE1
 SG2
O
PHE C:111 C:111 56.0 0.267 G -111.7 8.9 NA NA NA
PHE D:111 D:111 50.0 0.238 G -111.5 11.9 NA NA NA
PHE E:111 E:111 63.0 0.3 G -113.0 1.0 NA NA NA
PHE F:111 F:111 49.0 0.233 G -102.5 27.7 NA NA NA
PHE G:111 G:111 54.0 0.257 G -86.8 -3.3 NA NA NA
PHE H:111 H:111 45.0 0.214 S -76.5 4.9 NA NA NA
3i6a 1 P08263 86.88 9e-139 X-RAY
 2009-09-01 PHE A:111 A:111 49.0 0.233 G -95.7 -5.6 49.0 0.233 0.0 GSH
HOH
 7.573
8.518
 CZ
CE2
 SG2
O
PHE B:111 B:111 57.0 0.271 G -106.4 33.0 57.0 0.271 0.0 GSH
HOH
 7.405
3.605
 CE1
CE1
 SG2
O
PHE C:111 C:111 54.0 0.257 G -92.3 0.4 NA NA NA
PHE D:111 D:111 53.0 0.252 G -106.9 12.8 NA NA NA
PHE E:111 E:111 63.0 0.3 G -107.9 6.7 NA NA NA
PHE F:111 F:111 58.0 0.276 G -99.5 8.8 NA NA NA
PHE G:111 G:111 51.0 0.243 G -95.1 -2.0 NA NA NA
PHE H:111 H:111 57.0 0.271 G -106.2 13.5 NA NA NA
3ik9 1 P08263 86.88 9e-139 X-RAY
 2010-06-23 PHE A:111 A:111 38.0 0.181 G -109.4 -16.4 38.0 0.181 0.0 BOB
 3.863
 CE2
 C55
PHE B:111 B:111 56.0 0.267 G -100.6 35.1 56.0 0.267 0.0 BOB
 4.000
 CE1
 C54
PHE C:111 C:111 47.0 0.224 G -93.0 -14.1 NA NA NA
PHE D:111 D:111 48.0 0.229 G -109.4 2.8 NA NA NA
PHE E:111 E:111 42.0 0.2 G -106.9 4.5 NA NA NA
PHE F:111 F:111 58.0 0.276 G -120.3 22.4 NA NA NA
PHE G:111 G:111 49.0 0.233 G -86.6 8.8 NA NA NA
PHE H:111 H:111 42.0 0.2 G -101.5 -1.4 NA NA NA
6zj9 1 M9ZT87 80.63 1e-132 X-RAY
 2020-11-18 ILE A:111 A:111 56.0 0.32 G -105.6 26.9 56.0 0.32 0.0 GSH
HOH
 9.136
6.129
 CD1
N
 SG2
O
6zjc 1 M9ZT87 80.63 1e-132 X-RAY
 2020-11-18 ILE A:111 B:111 74.0 0.423 G -109.5 16.7 74.0 0.423 0.0 GSH
QLT
MPD
HOH
 9.575
6.217
4.057
6.748
 CD1
CD1
CG2
N
 SG2
C07
C5
O
ILE B:111 A:111 48.0 0.274 G -107.7 12.9 48.0 0.274 0.0 QLT
MPD
HOH
 6.679
4.551
8.923
 CG2
CG2
CG2
 C01
C5
O
ILE C:111 D:111 70.0 0.4 G -109.1 15.7 NA NA NA
ILE D:111 C:111 61.0 0.349 G -109.8 15.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16772-f1 1 Q16772 100.0 4e-164 LEU A:111 A:111 63.0 0.371 G -95.1 -7.2
af-p08263-f1 1 P08263 90.54 2e-146 VAL A:111 A:111 48.0 0.31 G -88.8 -5.9
af-p09210-f1 1 P09210 88.74 2e-143 PHE A:111 A:111 57.0 0.271 G -93.5 -3.3
af-q7rtv2-f1 1 Q7RTV2 85.59 7e-139 ILE A:111 A:111 71.0 0.406 T -124.6 3.2