Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr6 | 87796039 | . | T | A | CCDS5007.1:NM_000735.3:c.202Aag>Tag_NP_000726.1:p.68K>* | Homo sapiens glycoprotein hormones, alpha polypeptide (CGA), transcript variant 2, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7fig | 6 | P01215 | 100.0 | 7e-85 |
EM |
2021-09-29 | LYS | F:68 | X:44 | 54.0 | 0.27 | H | -54.3 | -42.4 | 54.0 | 0.27 | 0.0 |
NAG |
8.300 |
NZ |
O7 |
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| 7fii | 5 | P01215 | 100.0 | 7e-85 |
EM |
2021-09-29 | LYS | E:68 | X:44 | 51.0 | NA | H | -62.6 | -41.9 | 51.0 | NA | NA | ||||||
| 7fih | 5 | P01215 | 100.0 | 6e-84 |
EM |
2021-09-29 | LYS | E:67 | X:44 | 106.0 | 0.53 | H | -64.6 | -39.8 | 106.0 | 0.53 | 0.0 | ||||||
| 1dz7 | 1 | P01215 | 100.0 | 7e-66 |
NMR |
2000-02-29 | LYS | A:44 | A:44 | 124.0 | 0.62 | -37.7 | 144.1 | 124.0 | 0.62 | 0.0 | |||||||
| 1e9j | 1 | P01215 | 100.0 | 7e-66 |
NMR |
2002-07-25 | LYS | A:44 | A:44 | 181.0 | 0.905 | S | -48.7 | -81.3 | 181.0 | 0.905 | 0.0 |
NAG |
8.870 |
H |
H4 |
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| 1fl7 | 1 | P01215 | 100.0 | 7e-66 |
X-RAY |
2001-03-14 | LYS | A:44 | A:44 | 87.0 | 0.435 | H | -63.5 | -11.6 | 72.0 | 0.36 | 0.075 |
B:P01225:0.075 |
NAG NDG |
5.433 6.373 |
NZ NZ |
O3 C6 |
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| LYS | C:44 | C:44 | 48.0 | 0.24 | H | -66.2 | -16.3 | NA | NA | NA | |||||||||||||
| 1hcn | 1 | P01215 | 100.0 | 7e-66 |
X-RAY |
1994-09-30 | LYS | A:44 | A:44 | 71.0 | 0.355 | H | -58.3 | -29.6 | 71.0 | 0.355 | 0.0 |
NAG HOH |
8.437 2.817 |
CE NZ |
O7 O |
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| 1hd4 | 1 | P01215 | 100.0 | 7e-66 |
NMR |
2000-12-07 | LYS | A:44 | A:44 | 133.0 | 0.665 | S | -160.1 | 38.4 | 133.0 | 0.665 | 0.0 | ||||||
| 1xwd | 1 | P01215 | 100.0 | 7e-66 |
X-RAY |
2005-01-25 | LYS | A:44 | A:44 | 42.0 | 0.21 | H | -53.6 | -15.2 | 27.0 | 0.135 | 0.075 |
B:P01225:0.075 |
NAG HOH |
3.924 5.219 |
NZ NZ |
O6 O |
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| LYS | D:44 | D:44 | 47.0 | 0.235 | G | -58.9 | -5.3 | NA | NA | NA | |||||||||||||
| 4mqw | 1 | Q96QJ4 | 98.91 | 3e-65 |
X-RAY |
2014-04-09 | LYS | A:44 | A:44 | 56.0 | 0.28 | H | -55.2 | -28.2 | 28.0 | 0.14 | 0.14 |
B:P01225:0.14 |
NAG HOH |
2.920 3.841 |
NZ O |
O6 O |
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| LYS | D:44 | D:44 | 52.0 | 0.26 | H | -52.0 | -31.6 | NA | NA | NA | |||||||||||||
| LYS | G:44 | G:44 | 55.0 | 0.275 | H | -57.0 | -34.9 | NA | NA | NA | |||||||||||||
| 1hrp | 1 | P01215 | 98.91 | 3e-65 |
X-RAY |
1994-11-01 | LYS | A:44 | A:44 | 66.0 | 0.33 | H | -57.1 | -36.3 | 66.0 | 0.33 | 0.0 |
NAG |
8.223 |
NZ |
O7 |
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| 1qfw | 1 | P01215 | 98.91 | 3e-65 |
X-RAY |
2000-04-26 | LYS | A:44 | A:44 | 65.0 | 0.325 | H | -53.9 | -11.1 | 39.0 | 0.195 | 0.13 |
E:None:0.13 |
NAG |
7.444 |
NZ |
N2 |
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| 4ay9 | 1 | Q96QJ4 | 98.91 | 3e-65 |
X-RAY |
2012-08-08 | LYS | A:44 | A:44 | 54.0 | 0.27 | H | -57.8 | -31.4 | NA | NA | NA | ||||||
| LYS | C:44 | D:44 | 56.0 | 0.28 | H | -53.5 | -34.1 | 32.0 | 0.16 | 0.12 |
D:P01225:0.12 |
NAG HOH |
3.489 6.331 |
NZ NZ |
O6 O |
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| LYS | E:44 | G:44 | 55.0 | 0.275 | H | -52.6 | -36.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p01215-f1 | 1 | P01215 | 100.0 | 3e-85 | LYS | A:68 | A:68 | 46.0 | 0.23 | H | -60.0 | -33.5 | |