Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100771765 | . | G | A | CCDS5711.1:NM_000602.4:c.91Gtg>Atg_NP_000593.1:p.31V>M | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | VAL | A:31 | A:31 | 2.0 | 0.013 | H | -65.4 | -44.4 | 2.0 | 0.013 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | VAL | A:8 | A:8 | 0.0 | 0.0 | H | -67.5 | -25.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.340 |
CG2 |
O |
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| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | VAL | A:8 | A:8 | 5.0 | 0.032 | H | -68.0 | -29.3 | 5.0 | 0.032 | 0.0 |
DMS HOH |
9.388 6.101 |
N CG2 |
C1 O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | VAL | A:12 | A:8 | 10.0 | 0.065 | H | -60.6 | -39.1 | 10.0 | 0.065 | 0.0 |
TB7 HOH |
4.539 6.979 |
O O |
C1 O |
||
| VAL | B:12 | B:8 | 10.0 | 0.065 | H | -63.7 | -37.8 | NA | NA | NA | |||||||||||||
| VAL | C:12 | C:8 | 11.0 | 0.071 | H | -55.4 | -45.8 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | VAL | A:8 | A:8 | 4.0 | 0.026 | H | -68.3 | -35.8 | 4.0 | 0.026 | 0.0 |
HOH |
7.355 |
O |
O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:8 | A:8 | 12.0 | 0.077 | H | -74.3 | -28.7 | 12.0 | 0.077 | 0.0 |
HOH |
3.553 |
N |
O |
||
| VAL | B:8 | B:8 | 2.0 | 0.013 | H | -70.6 | -29.3 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:8 | A:8 | 9.0 | 0.058 | H | -76.3 | -34.7 | 9.0 | 0.058 | 0.0 |
HOH |
6.333 |
CG2 |
O |
||
| VAL | B:8 | B:8 | 3.0 | 0.019 | H | -65.8 | -37.2 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:8 | A:8 | 1.0 | 0.006 | H | -65.6 | -31.5 | 1.0 | 0.006 | 0.0 |
HOH |
7.000 |
O |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | VAL | A:8 | A:8 | 11.0 | 0.071 | H | -68.0 | -32.6 | 11.0 | 0.071 | 0.0 |
HOH |
6.994 |
O |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:8 | A:8 | 2.0 | 0.013 | H | -81.8 | -29.3 | 2.0 | 0.013 | 0.0 |
HOH |
6.853 |
O |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | VAL | A:8 | A:31 | 14.0 | 0.09 | H | -64.9 | -49.9 | 14.0 | 0.09 | 0.0 |
HOH |
3.726 |
CG1 |
O |
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| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | VAL | A:21 | A:8 | 1.0 | 0.006 | H | -72.9 | -29.5 | 1.0 | 0.006 | 0.0 |
HOH |
2.824 |
HG13 |
O |
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| VAL | B:21 | B:8 | 1.0 | 0.006 | H | -72.3 | -28.0 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | VAL | A:8 | A:8 | 5.0 | 0.032 | H | -73.3 | -47.4 | 5.0 | 0.032 | 0.0 | ||||||
| VAL | B:8 | B:8 | 5.0 | 0.032 | H | -93.5 | -44.3 | NA | NA | NA | |||||||||||||
| VAL | C:8 | C:8 | 8.0 | 0.052 | H | -86.2 | -53.3 | NA | NA | NA | |||||||||||||
| VAL | D:8 | D:8 | 7.0 | 0.045 | -101.3 | -46.5 | NA | NA | NA | ||||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | VAL | A:8 | A:8 | 2.0 | 0.013 | H | -73.7 | -32.7 | 2.0 | 0.013 | 0.0 |
HOH |
7.172 |
O |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:8 | I:8 | 115.0 | 0.742 | 360.0 | -65.6 | 115.0 | 0.742 | 0.0 |
HOH |
2.430 |
O |
O |
|||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | VAL | A:8 | A:8 | 12.0 | 0.077 | H | -72.5 | -37.7 | 12.0 | 0.077 | 0.0 | ||||||
| VAL | B:8 | B:8 | 12.0 | 0.077 | H | -71.6 | -39.5 | NA | NA | NA | |||||||||||||
| VAL | C:8 | C:8 | 7.0 | 0.045 | H | -67.4 | -35.1 | NA | NA | NA | |||||||||||||
| VAL | D:8 | D:8 | 8.0 | 0.052 | H | -74.6 | -35.2 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | VAL | A:8 | A:8 | 1.0 | 0.006 | H | -56.0 | -31.0 | 1.0 | 0.006 | 0.0 |
HOH |
6.320 |
N |
O |
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| VAL | B:8 | B:8 | 0.0 | 0.0 | H | -63.2 | -31.7 | NA | NA | NA | |||||||||||||
| VAL | C:8 | C:8 | 4.0 | 0.026 | H | -57.7 | -45.2 | NA | NA | NA | |||||||||||||
| VAL | D:8 | D:8 | 1.0 | 0.006 | H | -61.7 | -20.1 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | VAL | A:8 | I:8 | 2.0 | 0.013 | H | -68.0 | -25.8 | 2.0 | 0.013 | 0.0 |
HOH |
6.226 |
C |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | VAL | A:8 | A:8 | 10.0 | 0.065 | H | -73.5 | -39.1 | 10.0 | 0.065 | 0.0 | ||||||
| VAL | B:8 | B:8 | 0.0 | 0.0 | H | -66.6 | -39.1 | NA | NA | NA | |||||||||||||
| VAL | C:8 | C:8 | 4.0 | 0.026 | H | -69.1 | -39.4 | NA | NA | NA | |||||||||||||
| VAL | D:8 | D:8 | 0.0 | 0.0 | H | -62.5 | -40.6 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | VAL | A:8 | A:8 | 0.0 | 0.0 | H | -70.0 | -26.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.510 |
N |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:8 | A:8 | 4.0 | 0.026 | H | -71.2 | -40.0 | 4.0 | 0.026 | 0.0 | ||||||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:8 | A:8 | 0.0 | 0.0 | H | -62.5 | -44.1 | 0.0 | 0.0 | 0.0 | ||||||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | VAL | A:8 | A:8 | 10.0 | 0.065 | H | -67.9 | -33.8 | 10.0 | 0.065 | 0.0 |
HOH |
3.230 |
N |
O |
||
| VAL | B:8 | B:8 | 8.0 | 0.052 | H | -61.7 | -42.3 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | VAL | A:6 | A:8 | 2.0 | 0.013 | H | -57.0 | -47.1 | 2.0 | 0.013 | 0.0 | ||||||
| VAL | B:6 | B:8 | 3.0 | 0.019 | H | -55.3 | -50.3 | 3.0 | 0.019 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:5 | A:8 | 1.0 | 0.006 | H | -70.0 | -35.6 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | B:5 | B:8 | 0.0 | 0.0 | H | -69.0 | -32.4 | NA | NA | NA | |||||||||||||
| VAL | C:5 | C:8 | 3.0 | 0.019 | H | -68.6 | -35.1 | NA | NA | NA | |||||||||||||
| VAL | D:5 | D:8 | 0.0 | 0.0 | H | -69.5 | -39.4 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:5 | A:8 | 6.0 | 0.039 | H | -65.7 | -35.8 | 6.0 | 0.039 | 0.0 |
HOH |
3.473 |
N |
O |
||
| VAL | B:5 | B:8 | 1.0 | 0.006 | H | -67.0 | -39.8 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | VAL | A:4 | A:8 | 14.0 | 0.09 | H | -63.6 | -38.4 | 14.0 | 0.09 | 0.0 | ||||||
| VAL | B:4 | B:8 | 1.0 | 0.006 | H | -63.6 | -47.9 | NA | NA | NA | |||||||||||||
| VAL | C:4 | C:8 | 5.0 | 0.032 | H | -66.6 | -40.6 | NA | NA | NA | |||||||||||||
| VAL | D:4 | D:8 | 1.0 | 0.006 | H | -62.3 | -41.6 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | VAL | A:3 | I:8 | 3.0 | 0.019 | T | -84.3 | -34.6 | 3.0 | 0.019 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | VAL | A:8 | A:26 | 0.0 | 0.0 | H | -65.4 | -31.1 | 0.0 | 0.0 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | THR | A:8 | A:8 | 15.0 | 0.107 | H | -56.3 | -47.4 | 15.0 | 0.107 | 0.0 |
HOH |
2.920 |
OG1 |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | VAL | A:31 | A:31 | 0.0 | 0.0 | H | -66.5 | -38.7 | |