Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100771811 | . | T | A | CCDS5711.1:NM_000602.4:c.137gTg>gAg_NP_000593.1:p.46V>E | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | VAL | A:46 | A:46 | 1.0 | 0.006 | H | -57.0 | -48.9 | 1.0 | 0.006 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | VAL | A:23 | A:23 | 3.0 | 0.019 | H | -68.6 | -29.7 | 3.0 | 0.019 | 0.0 |
HOH |
2.571 |
O |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | VAL | A:23 | A:23 | 5.0 | 0.032 | H | -62.3 | -43.2 | 5.0 | 0.032 | 0.0 |
HOH |
2.736 |
O |
O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | VAL | A:27 | A:23 | 2.0 | 0.013 | H | -71.6 | -40.8 | 2.0 | 0.013 | 0.0 |
HOH |
4.720 |
CA |
O |
||
| VAL | B:27 | B:23 | 2.0 | 0.013 | H | -61.2 | -48.3 | NA | NA | NA | |||||||||||||
| VAL | C:27 | C:23 | 3.0 | 0.019 | H | -65.4 | -33.5 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | VAL | A:23 | A:23 | 6.0 | 0.039 | H | -64.3 | -45.9 | 6.0 | 0.039 | 0.0 |
HOH |
6.082 |
CG1 |
O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:23 | A:23 | 10.0 | 0.065 | H | -60.9 | -45.3 | 10.0 | 0.065 | 0.0 |
HOH |
7.135 |
O |
O |
||
| VAL | B:23 | B:23 | 8.0 | 0.052 | H | -73.1 | -47.8 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:23 | A:23 | 9.0 | 0.058 | H | -73.2 | -40.4 | 9.0 | 0.058 | 0.0 |
HOH |
6.951 |
O |
O |
||
| VAL | B:23 | B:23 | 14.0 | 0.09 | H | -59.5 | -44.5 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:23 | A:23 | 13.0 | 0.084 | H | -70.5 | -49.2 | 13.0 | 0.084 | 0.0 |
HOH |
6.839 |
N |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | VAL | A:23 | A:23 | 14.0 | 0.09 | H | -62.6 | -48.2 | 14.0 | 0.09 | 0.0 |
HOH |
2.805 |
O |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:23 | A:23 | 11.0 | 0.071 | H | -68.6 | -49.9 | 11.0 | 0.071 | 0.0 |
HOH |
5.723 |
CA |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | VAL | A:23 | A:46 | 7.0 | 0.045 | H | -59.5 | -33.6 | 7.0 | 0.045 | 0.0 | ||||||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | VAL | A:36 | A:23 | 9.0 | 0.058 | H | -61.3 | -42.4 | 9.0 | 0.058 | 0.0 |
HOH |
3.609 |
HG13 |
O |
||
| VAL | B:36 | B:23 | 12.0 | 0.077 | H | -64.7 | -38.5 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | VAL | A:23 | A:23 | 9.0 | 0.058 | H | -64.2 | -29.1 | 9.0 | 0.058 | 0.0 | ||||||
| VAL | B:23 | B:23 | 8.0 | 0.052 | H | -63.9 | -29.8 | NA | NA | NA | |||||||||||||
| VAL | C:23 | C:23 | 9.0 | 0.058 | H | -64.0 | -29.2 | NA | NA | NA | |||||||||||||
| VAL | D:23 | D:23 | 10.0 | 0.065 | H | -63.8 | -29.5 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | VAL | A:23 | A:23 | 14.0 | 0.09 | H | -61.5 | -52.9 | 14.0 | 0.09 | 0.0 |
HOH |
2.968 |
O |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:23 | I:23 | 20.0 | 0.129 | H | -71.6 | -36.8 | 20.0 | 0.129 | 0.0 |
HOH |
5.921 |
C |
O |
||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | VAL | A:23 | A:23 | 10.0 | 0.065 | H | -73.3 | -47.1 | 10.0 | 0.065 | 0.0 | ||||||
| VAL | B:23 | B:23 | 15.0 | 0.097 | H | -69.9 | -50.3 | NA | NA | NA | |||||||||||||
| VAL | C:23 | C:23 | 15.0 | 0.097 | H | -77.1 | -47.9 | NA | NA | NA | |||||||||||||
| VAL | D:23 | D:23 | 13.0 | 0.084 | H | -74.1 | -50.6 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | VAL | A:23 | A:23 | 11.0 | 0.071 | H | -67.9 | -36.1 | 11.0 | 0.071 | 0.0 |
HOH |
4.876 |
N |
O |
||
| VAL | B:23 | B:23 | 9.0 | 0.058 | H | -69.6 | -39.0 | NA | NA | NA | |||||||||||||
| VAL | C:23 | C:23 | 12.0 | 0.077 | H | -68.9 | -28.6 | NA | NA | NA | |||||||||||||
| VAL | D:23 | D:23 | 10.0 | 0.065 | H | -66.0 | -34.1 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | VAL | A:23 | I:23 | 9.0 | 0.058 | H | -73.6 | -40.1 | 9.0 | 0.058 | 0.0 |
HOH |
3.025 |
O |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | VAL | A:23 | A:23 | 10.0 | 0.065 | H | -67.2 | -31.8 | 10.0 | 0.065 | 0.0 | ||||||
| VAL | B:23 | B:23 | 12.0 | 0.077 | H | -72.0 | -37.1 | NA | NA | NA | |||||||||||||
| VAL | C:23 | C:23 | 11.0 | 0.071 | H | -67.3 | -26.9 | NA | NA | NA | |||||||||||||
| VAL | D:23 | D:23 | 9.0 | 0.058 | H | -68.9 | -39.9 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | VAL | A:23 | A:23 | 13.0 | 0.084 | H | -72.8 | -39.5 | 13.0 | 0.084 | 0.0 |
HOH |
7.341 |
N |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:23 | A:23 | 14.0 | 0.09 | H | -69.3 | -41.2 | 14.0 | 0.09 | 0.0 |
HOH |
2.760 |
O |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:23 | A:23 | 20.0 | 0.129 | H | -69.0 | -46.9 | 20.0 | 0.129 | 0.0 |
HOH |
6.144 |
O |
O |
||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | VAL | A:23 | A:23 | 14.0 | 0.09 | H | -64.5 | -48.8 | 14.0 | 0.09 | 0.0 |
HOH |
2.792 |
O |
O |
||
| VAL | B:23 | B:23 | 10.0 | 0.065 | H | -60.9 | -46.9 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | VAL | A:21 | A:23 | 11.0 | 0.071 | H | -59.6 | -46.0 | 11.0 | 0.071 | 0.0 | ||||||
| VAL | B:21 | B:23 | 9.0 | 0.058 | H | -57.2 | -51.5 | 0.0 | 0.0 | 0.058 |
A:P05121:0.058 |
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| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:20 | A:23 | 6.0 | 0.039 | H | -73.9 | -35.8 | 6.0 | 0.039 | 0.0 |
HOH |
3.620 |
O |
O |
||
| VAL | B:20 | B:23 | 8.0 | 0.052 | H | -76.2 | -37.3 | NA | NA | NA | |||||||||||||
| VAL | C:20 | C:23 | 7.0 | 0.045 | H | -73.3 | -30.9 | NA | NA | NA | |||||||||||||
| VAL | D:20 | D:23 | 7.0 | 0.045 | H | -70.9 | -32.7 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:20 | A:23 | 13.0 | 0.084 | H | -63.3 | -51.2 | 13.0 | 0.084 | 0.0 |
HOH |
4.381 |
CG1 |
O |
||
| VAL | B:20 | B:23 | 7.0 | 0.045 | H | -68.0 | -46.8 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | VAL | A:19 | A:23 | 10.0 | 0.065 | H | -71.3 | -30.5 | 10.0 | 0.065 | 0.0 | ||||||
| VAL | B:19 | B:23 | 9.0 | 0.058 | H | -71.4 | -39.1 | NA | NA | NA | |||||||||||||
| VAL | C:19 | C:23 | 11.0 | 0.071 | H | -74.0 | -32.3 | NA | NA | NA | |||||||||||||
| VAL | D:19 | D:23 | 14.0 | 0.09 | H | -69.9 | -35.8 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | VAL | A:18 | I:23 | 12.0 | 0.077 | H | -73.5 | -37.2 | 12.0 | 0.077 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | VAL | A:23 | A:41 | 3.0 | 0.019 | H | -67.1 | -36.9 | 3.0 | 0.019 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | VAL | A:23 | A:23 | 4.0 | 0.026 | H | -66.6 | -43.6 | 4.0 | 0.026 | 0.0 |
HOH |
3.936 |
CA |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | VAL | A:46 | A:46 | 5.0 | 0.032 | H | -66.1 | -46.9 | |