Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100771837 | . | G | A | CCDS5711.1:NM_000602.4:c.163Gtg>Atg_NP_000593.1:p.55V>M | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | VAL | A:55 | A:55 | 0.0 | 0.0 | -136.2 | 129.9 | 0.0 | 0.0 | 0.0 | |||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | VAL | A:32 | A:32 | 0.0 | 0.0 | E | -160.4 | 158.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.655 |
CG2 |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | VAL | A:32 | A:32 | 1.0 | 0.006 | E | -155.9 | 152.7 | 1.0 | 0.006 | 0.0 |
DMS HOH |
7.074 4.089 |
CG2 CG2 |
O O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | VAL | A:36 | A:32 | 0.0 | 0.0 | E | -145.2 | 148.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.177 |
CG2 |
O |
||
| VAL | B:36 | B:32 | 0.0 | 0.0 | E | -148.8 | 144.1 | NA | NA | NA | |||||||||||||
| VAL | C:36 | C:32 | 1.0 | 0.006 | E | -153.4 | 152.5 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | VAL | A:32 | A:32 | 5.0 | 0.032 | E | -141.1 | 119.5 | 5.0 | 0.032 | 0.0 |
HOH |
8.032 |
CG2 |
O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:32 | A:32 | 3.0 | 0.019 | E | -140.2 | 131.2 | 3.0 | 0.019 | 0.0 |
HOH |
7.468 |
N |
O |
||
| VAL | B:32 | B:32 | 3.0 | 0.019 | E | -128.3 | 126.3 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:32 | A:32 | 4.0 | 0.026 | E | -143.8 | 123.9 | 4.0 | 0.026 | 0.0 |
HOH |
6.041 |
N |
O |
||
| VAL | B:32 | B:32 | 5.0 | 0.032 | E | -125.6 | 136.5 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:32 | A:32 | 2.0 | 0.013 | E | -139.3 | 128.3 | 2.0 | 0.013 | 0.0 |
HOH |
6.186 |
N |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | VAL | A:32 | A:32 | 2.0 | 0.013 | E | -139.9 | 134.0 | 2.0 | 0.013 | 0.0 |
HOH |
4.113 |
CA |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:32 | A:32 | 1.0 | 0.006 | E | -142.2 | 126.3 | 1.0 | 0.006 | 0.0 |
HOH |
9.258 |
CG2 |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | VAL | A:32 | A:55 | 2.0 | 0.013 | E | -149.2 | 136.2 | 2.0 | 0.013 | 0.0 | ||||||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | VAL | A:45 | A:32 | 4.0 | 0.026 | E | -134.5 | 127.8 | 4.0 | 0.026 | 0.0 |
HOH |
5.351 |
HG13 |
O |
||
| VAL | B:45 | B:32 | 4.0 | 0.026 | E | -134.2 | 126.7 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | VAL | A:32 | A:32 | 8.0 | 0.052 | E | -152.2 | 121.8 | 8.0 | 0.052 | 0.0 | ||||||
| VAL | B:32 | B:32 | 7.0 | 0.045 | E | -152.7 | 121.6 | NA | NA | NA | |||||||||||||
| VAL | C:32 | C:32 | 7.0 | 0.045 | E | -152.9 | 122.2 | NA | NA | NA | |||||||||||||
| VAL | D:32 | D:32 | 8.0 | 0.052 | E | -152.8 | 122.1 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | VAL | A:32 | A:32 | 0.0 | 0.0 | E | -140.7 | 134.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.673 |
CG2 |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:32 | I:32 | 3.0 | 0.019 | E | -111.6 | 143.3 | 3.0 | 0.019 | 0.0 |
HOH |
7.332 |
CG2 |
O |
||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | VAL | A:32 | A:32 | 2.0 | 0.013 | E | -134.6 | 134.4 | 2.0 | 0.013 | 0.0 | ||||||
| VAL | B:32 | B:32 | 4.0 | 0.026 | E | -129.9 | 134.8 | NA | NA | NA | |||||||||||||
| VAL | C:32 | C:32 | 2.0 | 0.013 | E | -133.0 | 139.6 | NA | NA | NA | |||||||||||||
| VAL | D:32 | D:32 | 3.0 | 0.019 | E | -130.5 | 138.3 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | VAL | A:32 | A:32 | 9.0 | 0.058 | E | -144.8 | 116.5 | 9.0 | 0.058 | 0.0 |
HOH |
5.768 |
N |
O |
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| VAL | B:32 | B:32 | 4.0 | 0.026 | E | -155.8 | 131.2 | NA | NA | NA | |||||||||||||
| VAL | C:32 | C:32 | 8.0 | 0.052 | E | -155.9 | 139.1 | NA | NA | NA | |||||||||||||
| VAL | D:32 | D:32 | 6.0 | 0.039 | E | -159.6 | 108.3 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | VAL | A:32 | I:32 | 3.0 | 0.019 | E | -145.2 | 131.0 | 3.0 | 0.019 | 0.0 |
HOH |
4.072 |
CA |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | VAL | A:32 | A:32 | 2.0 | 0.013 | E | -155.0 | 127.7 | 2.0 | 0.013 | 0.0 | ||||||
| VAL | B:32 | B:32 | 4.0 | 0.026 | E | -141.0 | 141.0 | NA | NA | NA | |||||||||||||
| VAL | C:32 | C:32 | 3.0 | 0.019 | E | -146.9 | 129.2 | NA | NA | NA | |||||||||||||
| VAL | D:32 | D:32 | 4.0 | 0.026 | E | -156.4 | 139.6 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | VAL | A:32 | A:32 | 7.0 | 0.045 | E | -129.6 | 127.9 | 7.0 | 0.045 | 0.0 |
HOH |
5.798 |
N |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:32 | A:32 | 2.0 | 0.013 | E | -143.9 | 131.6 | 2.0 | 0.013 | 0.0 |
HOH |
3.477 |
CG2 |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:32 | A:32 | 5.0 | 0.032 | E | -148.5 | 118.9 | 5.0 | 0.032 | 0.0 |
HOH |
6.871 |
CG2 |
O |
||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | VAL | A:32 | A:32 | 5.0 | 0.032 | E | -142.0 | 132.6 | 5.0 | 0.032 | 0.0 |
HOH |
5.633 |
CG2 |
O |
||
| VAL | B:32 | B:32 | 3.0 | 0.019 | E | -136.2 | 131.7 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | VAL | A:30 | A:32 | 3.0 | 0.019 | E | -147.6 | 117.2 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | B:30 | B:32 | 2.0 | 0.013 | E | -154.5 | 127.7 | 0.0 | 0.0 | 0.013 |
A:P05121:0.013 |
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| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:29 | A:32 | 1.0 | 0.006 | E | -147.1 | 135.1 | 1.0 | 0.006 | 0.0 |
EDO HOH |
5.918 6.589 |
N CG2 |
C2 O |
||
| VAL | B:29 | B:32 | 1.0 | 0.006 | E | -144.1 | 127.8 | NA | NA | NA | |||||||||||||
| VAL | C:29 | C:32 | 2.0 | 0.013 | E | -127.9 | 131.4 | NA | NA | NA | |||||||||||||
| VAL | D:29 | D:32 | 6.0 | 0.039 | E | -132.3 | 127.5 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:29 | A:32 | 4.0 | 0.026 | E | -143.5 | 131.7 | 4.0 | 0.026 | 0.0 |
HOH |
4.167 |
CG2 |
O |
||
| VAL | B:29 | B:32 | 4.0 | 0.026 | E | -137.6 | 124.2 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | VAL | A:28 | A:32 | 3.0 | 0.019 | E | -149.8 | 125.7 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | B:28 | B:32 | 3.0 | 0.019 | E | -152.1 | 136.4 | NA | NA | NA | |||||||||||||
| VAL | C:28 | C:32 | 4.0 | 0.026 | E | -148.6 | 123.7 | NA | NA | NA | |||||||||||||
| VAL | D:28 | D:32 | 7.0 | 0.045 | E | -157.9 | 130.9 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | VAL | A:27 | I:32 | 3.0 | 0.019 | -106.3 | 136.6 | 3.0 | 0.019 | 0.0 | |||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | VAL | A:32 | A:50 | 34.0 | 0.219 | -139.9 | 110.3 | 2.0 | 0.013 | 0.206 |
B:P05121:0.206 |
||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | VAL | A:32 | A:32 | 1.0 | 0.006 | E | -140.2 | 131.1 | 1.0 | 0.006 | 0.0 |
HOH |
5.223 |
CG1 |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | VAL | A:55 | A:55 | 1.0 | 0.006 | E | -138.3 | 133.0 | |