Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100771940 | . | T | A | CCDS5711.1:NM_000602.4:c.266aTt>aAt_NP_000593.1:p.89I>N | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | ILE | A:89 | A:89 | 1.0 | 0.006 | T | -57.6 | -28.3 | 1.0 | 0.006 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | ILE | A:66 | A:66 | 1.0 | 0.006 | T | -62.6 | -27.9 | 1.0 | 0.006 | 0.0 |
HOH |
2.738 |
O |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | ILE | A:66 | A:66 | 1.0 | 0.006 | T | -57.7 | -27.7 | 1.0 | 0.006 | 0.0 |
HOH |
2.831 |
O |
O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | ILE | A:70 | A:66 | 4.0 | 0.023 | T | -70.6 | -14.8 | 4.0 | 0.023 | 0.0 |
TB7 HOH |
3.879 8.581 |
CD1 O |
C3 O |
||
| ILE | B:70 | B:66 | 4.0 | 0.023 | T | -74.5 | -29.6 | NA | NA | NA | |||||||||||||
| ILE | C:70 | C:66 | 7.0 | 0.04 | T | -73.7 | -18.7 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | ILE | A:66 | A:66 | 0.0 | 0.0 | T | -62.2 | -31.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.562 |
N |
O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ILE | A:66 | A:66 | 1.0 | 0.006 | T | -69.0 | -24.3 | 1.0 | 0.006 | 0.0 |
HOH |
2.717 |
O |
O |
||
| ILE | B:66 | B:66 | 1.0 | 0.006 | T | -63.7 | -27.9 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ILE | A:66 | A:66 | 12.0 | 0.069 | T | -59.2 | -14.2 | 12.0 | 0.069 | 0.0 |
HOH |
3.256 |
O |
O |
||
| ILE | B:66 | B:66 | 2.0 | 0.011 | T | -61.9 | -27.0 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | ILE | A:66 | A:66 | 1.0 | 0.006 | T | -66.2 | -24.0 | 1.0 | 0.006 | 0.0 |
HOH |
5.459 |
N |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | ILE | A:66 | A:66 | 3.0 | 0.017 | T | -64.6 | -24.4 | 3.0 | 0.017 | 0.0 |
HOH |
4.827 |
CD1 |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | ILE | A:66 | A:66 | 1.0 | 0.006 | T | -65.2 | -21.9 | 1.0 | 0.006 | 0.0 |
HOH |
8.716 |
N |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | ILE | A:66 | A:89 | 1.0 | 0.006 | T | -50.5 | -19.4 | 1.0 | 0.006 | 0.0 |
HOH |
7.807 |
O |
O |
||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | ILE | A:79 | A:66 | 3.0 | 0.017 | T | -62.4 | -21.7 | 3.0 | 0.017 | 0.0 |
HOH |
2.513 |
HG22 |
O |
||
| ILE | B:79 | B:66 | 1.0 | 0.006 | T | -70.5 | -27.9 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | ILE | A:66 | A:66 | 4.0 | 0.023 | T | -54.4 | -35.8 | 4.0 | 0.023 | 0.0 | ||||||
| ILE | B:66 | B:66 | 4.0 | 0.023 | T | -55.3 | -37.4 | NA | NA | NA | |||||||||||||
| ILE | C:66 | C:66 | 4.0 | 0.023 | T | -54.1 | -37.6 | NA | NA | NA | |||||||||||||
| ILE | D:66 | D:66 | 4.0 | 0.023 | T | -54.5 | -38.1 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | ILE | A:66 | A:66 | 2.0 | 0.011 | T | -62.9 | -28.8 | 2.0 | 0.011 | 0.0 |
HOH |
2.619 |
O |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:66 | I:66 | 2.0 | 0.011 | T | -50.1 | -17.2 | 2.0 | 0.011 | 0.0 |
HOH |
7.979 |
CD1 |
O |
||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | ILE | A:66 | A:66 | 2.0 | 0.011 | T | -71.5 | -34.5 | 2.0 | 0.011 | 0.0 | ||||||
| ILE | B:66 | B:66 | 2.0 | 0.011 | T | -65.3 | -24.4 | NA | NA | NA | |||||||||||||
| ILE | C:66 | C:66 | 2.0 | 0.011 | T | -70.5 | -44.5 | NA | NA | NA | |||||||||||||
| ILE | D:66 | D:66 | 1.0 | 0.006 | S | -68.2 | -36.3 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | ILE | A:66 | A:66 | 3.0 | 0.017 | T | -64.5 | -19.5 | 3.0 | 0.017 | 0.0 |
HOH |
2.700 |
O |
O |
||
| ILE | B:66 | B:66 | 2.0 | 0.011 | T | -56.9 | -30.4 | NA | NA | NA | |||||||||||||
| ILE | C:66 | C:66 | 2.0 | 0.011 | S | -63.1 | -27.5 | NA | NA | NA | |||||||||||||
| ILE | D:66 | D:66 | 4.0 | 0.023 | T | -59.8 | -26.7 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | ILE | A:66 | I:66 | 2.0 | 0.011 | T | -58.1 | -28.5 | 2.0 | 0.011 | 0.0 |
HOH |
2.627 |
O |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | ILE | A:66 | A:66 | 3.0 | 0.017 | T | -59.5 | -31.0 | 3.0 | 0.017 | 0.0 | ||||||
| ILE | B:66 | B:66 | 3.0 | 0.017 | T | -60.6 | -28.0 | NA | NA | NA | |||||||||||||
| ILE | C:66 | C:66 | 3.0 | 0.017 | T | -65.8 | -24.8 | NA | NA | NA | |||||||||||||
| ILE | D:66 | D:66 | 1.0 | 0.006 | T | -66.8 | -21.8 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | ILE | A:66 | A:66 | 2.0 | 0.011 | T | -57.4 | -26.7 | 2.0 | 0.011 | 0.0 |
HOH |
2.619 |
O |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ILE | A:66 | A:66 | 2.0 | 0.011 | T | -73.4 | -23.4 | 2.0 | 0.011 | 0.0 | ||||||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ILE | A:66 | A:66 | 12.0 | 0.069 | T | -78.4 | -2.9 | 12.0 | 0.069 | 0.0 | ||||||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | ILE | A:66 | A:66 | 1.0 | 0.006 | T | -62.8 | -26.5 | 1.0 | 0.006 | 0.0 |
HOH |
2.648 |
O |
O |
||
| ILE | B:66 | B:66 | 3.0 | 0.017 | T | -61.9 | -28.2 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | ILE | A:64 | A:66 | 3.0 | 0.017 | T | -61.7 | -21.4 | 3.0 | 0.017 | 0.0 | ||||||
| ILE | B:64 | B:66 | 4.0 | 0.023 | T | -54.8 | -25.3 | 4.0 | 0.023 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ILE | A:63 | A:66 | 4.0 | 0.023 | T | -66.4 | -29.0 | 4.0 | 0.023 | 0.0 |
HOH |
8.559 |
N |
O |
||
| ILE | B:63 | B:66 | 3.0 | 0.017 | T | -66.3 | -26.5 | NA | NA | NA | |||||||||||||
| ILE | C:63 | C:66 | 2.0 | 0.011 | T | -69.1 | -30.9 | NA | NA | NA | |||||||||||||
| ILE | D:63 | D:66 | 5.0 | 0.029 | T | -67.3 | -27.4 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ILE | A:63 | A:66 | 2.0 | 0.011 | T | -58.6 | -30.4 | 2.0 | 0.011 | 0.0 |
HOH |
2.733 |
O |
O |
||
| ILE | B:63 | B:66 | 3.0 | 0.017 | T | -62.0 | -31.5 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | ILE | A:62 | A:66 | 2.0 | 0.011 | T | -58.7 | -23.5 | 2.0 | 0.011 | 0.0 | ||||||
| ILE | B:62 | B:66 | 2.0 | 0.011 | T | -61.7 | -26.4 | NA | NA | NA | |||||||||||||
| ILE | C:62 | C:66 | 5.0 | 0.029 | T | -59.3 | -37.5 | NA | NA | NA | |||||||||||||
| ILE | D:62 | D:66 | 3.0 | 0.017 | T | -61.6 | -31.9 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | ILE | A:61 | I:66 | 1.0 | 0.006 | S | -109.1 | -36.3 | 1.0 | 0.006 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | ILE | A:66 | A:84 | 2.0 | 0.011 | T | -64.8 | -6.4 | 2.0 | 0.011 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | VAL | A:66 | A:66 | 1.0 | 0.006 | T | -57.8 | -32.7 | 1.0 | 0.006 | 0.0 |
HOH |
2.536 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | ILE | A:89 | A:89 | 3.0 | 0.017 | T | -66.3 | -27.5 | |