Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100773742 . G A CCDS5711.1:NM_000602.4:c.312gaG>gaA_NP_000593.1:p.104E>E Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 GLU A:104 A:104 34.0 0.179 H -74.3 -32.4 34.0 0.179 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 GLU A:81 A:81 37.0 0.195 H -67.3 -40.6 37.0 0.195 0.0 HOH
 2.776
 OE1
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 GLU A:81 A:81 29.0 0.153 H -66.9 -38.8 29.0 0.153 0.0 DMS
HOH
 8.353
2.644
 OE2
OE2
 C1
O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 GLU A:85 A:81 46.0 0.242 H -58.2 -46.7 46.0 0.242 0.0 TB7
HOH
 9.223
3.833
 N
CG
 C9
O
GLU B:85 B:81 51.0 0.268 H -55.9 -35.9 NA NA NA
GLU C:85 C:81 36.0 0.189 H -71.6 -32.0 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 GLU A:81 A:81 53.0 0.279 H -62.2 -41.0 53.0 0.279 0.0 HOH
 2.980
 OE1
 O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 GLU A:81 A:81 109.0 0.574 H -69.7 -36.7 109.0 0.574 0.0 HOH
 7.746
 N
 O
GLU B:81 B:81 104.0 0.547 H -67.3 -35.0 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 GLU A:81 A:81 77.0 0.405 H -75.0 -34.8 77.0 0.405 0.0 HOH
 2.833
 OE2
 O
GLU B:81 B:81 88.0 0.463 H -71.4 -31.0 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 GLU A:81 A:81 61.0 NA H -54.5 -42.1 61.0 NA NA HOH
 2.660
 O
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 GLU A:81 A:81 112.0 0.589 H -93.8 -34.5 112.0 0.589 0.0 HOH
 8.969
 N
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 GLU A:81 A:81 92.0 0.484 H -78.0 -45.8 92.0 0.484 0.0
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 GLU A:81 A:104 65.0 0.342 H -60.8 -29.9 65.0 0.342 0.0 HOH
 9.006
 OE1
 O
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 GLU A:94 A:81 21.0 0.111 H -59.8 -49.4 21.0 0.111 0.0 HOH
 2.369
 OE2
 O
GLU B:94 B:81 20.0 0.105 H -43.1 -37.3 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 GLU A:81 A:81 65.0 0.342 H -61.1 -21.1 65.0 0.342 0.0
GLU B:81 B:81 63.0 0.332 H -60.0 -22.8 NA NA NA
GLU C:81 C:81 63.0 0.332 H -60.5 -20.8 NA NA NA
GLU D:81 D:81 62.0 0.326 H -60.3 -21.6 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 GLU A:81 A:81 61.0 0.321 H -52.3 -47.4 61.0 0.321 0.0 HOH
 3.053
 CG
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 GLU A:81 I:81 69.0 0.363 H -71.9 -40.2 69.0 0.363 0.0
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 GLU A:81 A:81 68.0 0.358 H -64.6 -46.0 68.0 0.358 0.0
GLU B:81 B:81 52.0 0.274 H -104.2 -22.3 NA NA NA
GLU C:81 C:81 78.0 0.411 H -81.1 -30.0 NA NA NA
GLU D:81 D:81 49.0 0.258 S -64.8 -40.4 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 GLU A:81 A:81 57.0 0.3 H -72.2 -45.5 57.0 0.3 0.0 HOH
 2.735
 O
 O
GLU B:81 B:81 69.0 0.363 H -89.3 -21.3 NA NA NA
GLU C:81 C:81 52.0 0.274 H -71.9 -63.7 NA NA NA
GLU D:81 D:81 57.0 0.3 H -62.1 -45.0 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 GLU A:81 I:81 93.0 0.489 H -68.1 -38.4 93.0 0.489 0.0 HOH
 2.816
 OE2
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 GLU A:81 A:81 94.0 0.495 H -65.4 -37.7 94.0 0.495 0.0 GDE
 9.892
 N
 OAA
GLU B:81 B:81 89.0 0.468 H -76.1 -30.7 NA NA NA
GLU C:81 C:81 79.0 0.416 H -63.3 -43.5 NA NA NA
GLU D:81 D:81 89.0 0.468 H -73.1 -28.4 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 GLU A:81 A:81 14.0 0.074 H -64.6 -42.3 14.0 0.074 0.0 HOH
 3.143
 OE1
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 GLU A:81 A:81 76.0 0.4 H -75.5 -26.9 76.0 0.4 0.0
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 GLU A:81 A:81 36.0 NA H -68.5 -39.9 36.0 NA NA
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 GLU A:81 A:81 67.0 0.353 H -64.0 -39.0 67.0 0.353 0.0 HOH
 3.669
 O
 O
GLU B:81 B:81 83.0 0.437 H -63.5 -40.5 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 GLU A:79 A:81 63.0 0.332 H -60.3 -31.4 63.0 0.332 0.0
GLU B:79 B:81 64.0 0.337 H -58.5 -24.0 64.0 0.337 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 GLU A:78 A:81 63.0 0.332 H -71.8 -42.2 63.0 0.332 0.0 HOH
 9.994
 N
 O
GLU B:78 B:81 72.0 0.379 H -70.1 -43.1 NA NA NA
GLU C:78 C:81 58.0 0.305 H -69.3 -37.1 NA NA NA
GLU D:78 D:81 60.0 0.316 H -72.2 -37.2 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 GLU A:78 A:81 74.0 0.389 H -60.6 -30.3 74.0 0.389 0.0 HOH
 6.822
 OE1
 O
GLU B:78 B:81 55.0 0.289 H -59.1 -44.8 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 GLU A:77 A:81 68.0 0.358 H -56.5 -44.7 68.0 0.358 0.0
GLU B:77 B:81 85.0 0.447 H -60.0 -22.1 NA NA NA
GLU C:77 C:81 68.0 0.358 H -55.0 -47.8 NA NA NA
GLU D:77 D:81 78.0 0.411 H -71.4 -25.7 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 GLU A:76 I:81 80.0 0.421 H -68.6 -46.3 80.0 0.421 0.0
9pai 1 P05121 99.71 0.0 X-RAY
 1999-03-19 GLU A:81 A:99 92.0 0.484 H -61.1 -32.3 55.0 0.289 0.195 B:P05121:0.195
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 GLU A:81 A:81 68.0 0.358 H -62.2 -44.3 68.0 0.358 0.0 HOH
 2.672
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 GLU A:104 A:104 48.0 0.253 H -60.3 -41.8