Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100773858 . C A CCDS5711.1:NM_000602.4:c.428aCg>aAg_NP_000593.1:p.143T>K Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 THR A:143 A:143 93.0 0.664 -109.1 148.0 93.0 0.664 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 THR A:120 A:120 75.0 0.536 63.2 116.2 75.0 0.536 0.0 HOH
 2.506
 O
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 THR A:120 A:120 96.0 0.686 -101.8 155.0 96.0 0.686 0.0 HOH
 2.540
 OG1
 O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 THR A:124 A:120 79.0 0.564 -136.6 135.6 79.0 0.564 0.0 TB7
HOH
 7.478
2.867
 N
N
 O16
O
THR B:124 B:120 74.0 0.529 -122.3 148.1 NA NA NA
THR C:124 C:120 84.0 0.6 -118.1 148.5 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 THR A:120 A:120 87.0 0.621 -86.7 144.4 87.0 0.621 0.0 HOH
 2.528
 O
 O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 THR A:120 A:120 50.0 0.357 -136.5 155.4 50.0 0.357 0.0 HOH
 2.785
 O
 O
THR B:120 B:120 59.0 0.421 -125.8 152.6 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 THR A:120 A:120 63.0 0.45 -128.6 154.0 63.0 0.45 0.0 HOH
 2.657
 O
 O
THR B:120 B:120 55.0 0.393 -125.0 157.5 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 THR A:120 A:120 64.0 0.457 -105.3 146.7 64.0 0.457 0.0 HOH
 2.615
 O
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 THR A:120 A:120 64.0 0.457 -113.8 147.3 64.0 0.457 0.0 HOH
 2.712
 O
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 THR A:120 A:120 44.0 0.314 -119.6 160.4 44.0 0.314 0.0 RV2
 2.616
 OG1
 O15
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 THR A:120 A:143 53.0 0.379 -151.2 170.8 53.0 0.379 0.0
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 THR A:133 A:120 72.0 0.514 E -64.6 133.3 72.0 0.514 0.0 HOH
 1.840
 H
 O
THR B:133 B:120 61.0 0.436 E -70.6 127.7 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 THR A:120 A:120 60.0 0.429 -131.3 145.3 60.0 0.429 0.0
THR B:120 B:120 61.0 0.436 -132.1 145.3 NA NA NA
THR C:120 C:120 62.0 0.443 -131.6 145.9 NA NA NA
THR D:120 D:120 61.0 0.436 -131.4 147.7 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 THR A:120 A:120 63.0 0.45 -126.8 172.4 10.0 0.071 0.379 B:P04004:0.379
 HOH
 2.759
 O
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 THR A:120 I:120 72.0 0.514 -122.9 171.6 72.0 0.514 0.0
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 THR A:120 A:120 62.0 0.443 -130.1 159.8 62.0 0.443 0.0 HOH
 2.964
 O
 O
THR B:120 B:120 64.0 0.457 -124.0 153.0 NA NA NA
THR C:120 C:120 76.0 0.543 -122.1 149.8 NA NA NA
THR D:120 D:120 74.0 0.529 -106.0 154.7 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 THR A:120 A:120 67.0 0.479 -126.3 150.4 67.0 0.479 0.0 HOH
 2.690
 O
 O
THR B:120 B:120 60.0 0.429 -118.0 154.7 NA NA NA
THR C:120 C:120 59.0 0.421 -129.9 175.9 NA NA NA
THR D:120 D:120 60.0 0.429 -121.0 153.5 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 THR A:120 I:120 71.0 0.507 -117.0 152.4 71.0 0.507 0.0 HOH
 2.964
 O
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 THR A:120 A:120 71.0 0.507 -114.9 152.9 71.0 0.507 0.0 GDE
 6.662
 N
 OAD
THR B:120 B:120 63.0 0.45 -114.3 158.6 NA NA NA
THR C:120 C:120 70.0 0.5 -123.8 155.1 NA NA NA
THR D:120 D:120 66.0 0.471 -128.0 152.5 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 THR A:120 A:120 129.0 0.921 360.0 152.3 129.0 0.921 0.0 HOH
 2.653
 O
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 THR A:120 A:120 66.0 0.471 -90.5 160.2 66.0 0.471 0.0 HOH
 2.669
 OG1
 O
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 THR A:120 A:120 75.0 0.536 -134.7 147.7 75.0 0.536 0.0 HOH
 2.623
 O
 O
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 THR A:120 A:120 74.0 0.529 -117.7 147.3 74.0 0.529 0.0 RV2
HOH
 2.593
2.631
 OG1
O
 O03
O
THR B:120 B:120 78.0 0.557 -125.6 147.3 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 THR A:118 A:120 65.0 0.464 -122.3 154.3 65.0 0.464 0.0
THR B:118 B:120 65.0 0.464 -126.3 147.1 65.0 0.464 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 THR A:117 A:120 68.0 0.486 -127.6 149.8 68.0 0.486 0.0 HOH
 2.701
 OG1
 O
THR B:117 B:120 71.0 0.507 -123.4 147.4 NA NA NA
THR C:117 C:120 68.0 0.486 -115.5 153.8 NA NA NA
THR D:117 D:120 66.0 0.471 -112.2 155.9 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 THR A:117 A:120 62.0 0.443 -122.8 160.4 62.0 0.443 0.0 HOH
 2.879
 O
 O
THR B:117 B:120 71.0 0.507 -122.8 160.6 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 THR A:116 A:120 64.0 0.457 -134.7 154.9 64.0 0.457 0.0
THR B:116 B:120 68.0 0.486 -125.3 153.5 NA NA NA
THR C:116 C:120 68.0 0.486 -130.2 149.0 NA NA NA
THR D:116 D:120 57.0 0.407 -125.9 162.3 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 THR A:115 I:120 70.0 0.5 -135.6 171.4 70.0 0.5 0.0
9pai 1 P05121 99.71 0.0 X-RAY
 1999-03-19 THR A:120 A:138 50.0 0.357 E -69.4 134.1 50.0 0.357 0.0
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 MET A:120 A:120 133.0 0.719 -91.7 139.0 133.0 0.719 0.0 HOH
 2.534
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 THR A:143 A:143 41.0 0.293 -128.3 150.3