Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100775188 | . | G | A | CCDS5711.1:NM_000602.4:c.538Gtg>Atg_NP_000593.1:p.180V>M | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | VAL | A:180 | A:180 | 10.0 | 0.065 | -145.2 | 135.1 | 10.0 | 0.065 | 0.0 | |||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | VAL | A:157 | A:157 | 2.0 | 0.013 | -120.6 | 161.6 | 2.0 | 0.013 | 0.0 |
HOH |
5.254 |
O |
O |
|||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | VAL | A:157 | A:157 | 1.0 | 0.006 | S | -132.2 | 152.5 | 1.0 | 0.006 | 0.0 |
DMS HOH |
5.802 2.670 |
N O |
S O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | VAL | A:161 | A:157 | 5.0 | 0.032 | S | -139.5 | 155.9 | 5.0 | 0.032 | 0.0 |
HOH |
6.243 |
N |
O |
||
| VAL | B:161 | B:157 | 6.0 | 0.039 | S | -112.1 | 131.6 | NA | NA | NA | |||||||||||||
| VAL | C:161 | C:157 | 4.0 | 0.026 | -129.0 | 147.9 | NA | NA | NA | ||||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | VAL | A:157 | A:157 | 6.0 | 0.039 | S | -126.7 | 151.6 | 2.0 | 0.013 | 0.026 |
C:None:0.026 |
HOH |
2.959 |
O |
O |
|
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:157 | A:157 | 4.0 | 0.026 | -129.9 | 157.2 | 4.0 | 0.026 | 0.0 |
HOH |
3.449 |
O |
O |
|||
| VAL | B:157 | B:157 | 4.0 | 0.026 | -135.4 | 151.6 | NA | NA | NA | ||||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | VAL | A:157 | A:157 | 3.0 | 0.019 | -127.5 | 139.5 | 3.0 | 0.019 | 0.0 |
HOH |
5.343 |
CA |
O |
|||
| VAL | B:157 | B:157 | 3.0 | 0.019 | -128.6 | 154.1 | NA | NA | NA | ||||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:157 | A:157 | 5.0 | 0.032 | S | -122.9 | 163.3 | 5.0 | 0.032 | 0.0 |
HOH |
3.026 |
O |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | VAL | A:157 | A:157 | 9.0 | 0.058 | S | -105.3 | 139.2 | 9.0 | 0.058 | 0.0 |
HOH |
2.763 |
N |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:157 | A:157 | 3.0 | 0.019 | -134.1 | 149.8 | 3.0 | 0.019 | 0.0 |
HOH |
2.793 |
O |
O |
|||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | VAL | A:157 | A:180 | 30.0 | 0.194 | 121.2 | 120.4 | 30.0 | 0.194 | 0.0 |
HOH |
7.242 |
CG2 |
O |
|||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | VAL | A:170 | A:157 | 2.0 | 0.013 | S | -131.5 | 134.6 | 2.0 | 0.013 | 0.0 |
HOH |
3.611 |
HA |
O |
||
| VAL | B:170 | B:157 | 2.0 | 0.013 | S | -122.2 | 138.5 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | VAL | A:157 | A:157 | 3.0 | 0.019 | -75.7 | 136.2 | 3.0 | 0.019 | 0.0 | |||||||
| VAL | B:157 | B:157 | 3.0 | 0.019 | -74.7 | 137.2 | NA | NA | NA | ||||||||||||||
| VAL | C:157 | C:157 | 3.0 | 0.019 | -75.1 | 136.6 | NA | NA | NA | ||||||||||||||
| VAL | D:157 | D:157 | 2.0 | 0.013 | -74.8 | 138.3 | NA | NA | NA | ||||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | VAL | A:157 | A:157 | 7.0 | 0.045 | S | -134.2 | 158.9 | 7.0 | 0.045 | 0.0 |
HOH |
3.047 |
O |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:157 | I:157 | 3.0 | 0.019 | -76.0 | 119.0 | 3.0 | 0.019 | 0.0 |
HOH |
8.657 |
CA |
O |
|||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | VAL | A:157 | A:157 | 1.0 | 0.006 | -73.6 | 119.0 | 1.0 | 0.006 | 0.0 | |||||||
| VAL | B:157 | B:157 | 1.0 | 0.006 | -61.2 | 139.9 | NA | NA | NA | ||||||||||||||
| VAL | C:157 | C:157 | 1.0 | 0.006 | -72.2 | 117.0 | NA | NA | NA | ||||||||||||||
| VAL | D:157 | D:157 | 1.0 | 0.006 | -60.9 | 101.8 | NA | NA | NA | ||||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | VAL | A:157 | A:157 | 0.0 | 0.0 | -75.5 | 120.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.273 |
N |
O |
|||
| VAL | B:157 | B:157 | 1.0 | 0.006 | -71.3 | 125.4 | NA | NA | NA | ||||||||||||||
| VAL | C:157 | C:157 | 2.0 | 0.013 | -70.5 | 130.1 | NA | NA | NA | ||||||||||||||
| VAL | D:157 | D:157 | 0.0 | 0.0 | -94.8 | 135.3 | NA | NA | NA | ||||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | VAL | A:157 | I:157 | 5.0 | 0.032 | -63.7 | 142.5 | 5.0 | 0.032 | 0.0 |
HOH |
5.441 |
O |
O |
|||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | VAL | A:157 | A:157 | 1.0 | 0.006 | -61.9 | 124.6 | 1.0 | 0.006 | 0.0 | |||||||
| VAL | B:157 | B:157 | 2.0 | 0.013 | -68.7 | 132.4 | NA | NA | NA | ||||||||||||||
| VAL | C:157 | C:157 | 1.0 | 0.006 | -63.8 | 121.8 | NA | NA | NA | ||||||||||||||
| VAL | D:157 | D:157 | 1.0 | 0.006 | -62.3 | 131.3 | NA | NA | NA | ||||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | VAL | A:157 | A:157 | 8.0 | 0.052 | -134.0 | 155.3 | 8.0 | 0.052 | 0.0 |
HOH |
4.553 |
CA |
O |
|||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:157 | A:157 | 2.0 | 0.013 | -56.9 | 127.4 | 2.0 | 0.013 | 0.0 |
HOH |
5.205 |
CA |
O |
|||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | VAL | A:157 | A:157 | 2.0 | 0.013 | -68.4 | 141.6 | 2.0 | 0.013 | 0.0 |
HOH |
9.225 |
N |
O |
|||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | VAL | A:157 | A:157 | 1.0 | 0.006 | -74.6 | 126.9 | 1.0 | 0.006 | 0.0 |
HOH |
5.516 |
O |
O |
|||
| VAL | B:157 | B:157 | 1.0 | 0.006 | -70.3 | 127.6 | NA | NA | NA | ||||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | VAL | A:155 | A:157 | 1.0 | 0.006 | -79.1 | 115.5 | 1.0 | 0.006 | 0.0 | |||||||
| VAL | B:155 | B:157 | 2.0 | 0.013 | -80.9 | 115.1 | 2.0 | 0.013 | 0.0 | ||||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:154 | A:157 | 2.0 | 0.013 | -73.7 | 139.4 | 2.0 | 0.013 | 0.0 |
HOH |
7.481 |
CG2 |
O |
|||
| VAL | B:154 | B:157 | 2.0 | 0.013 | -73.1 | 125.6 | NA | NA | NA | ||||||||||||||
| VAL | C:154 | C:157 | 3.0 | 0.019 | -71.6 | 123.2 | NA | NA | NA | ||||||||||||||
| VAL | D:154 | D:157 | 5.0 | NA | -73.0 | 111.5 | NA | NA | NA | ||||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | VAL | A:154 | A:157 | 2.0 | 0.013 | -65.5 | 130.1 | 2.0 | 0.013 | 0.0 |
HOH |
5.523 |
O |
O |
|||
| VAL | B:154 | B:157 | 1.0 | 0.006 | -56.9 | 132.1 | NA | NA | NA | ||||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | VAL | A:153 | A:157 | 2.0 | 0.013 | -70.6 | 151.1 | 2.0 | 0.013 | 0.0 | |||||||
| VAL | B:153 | B:157 | 1.0 | 0.006 | -73.8 | 132.7 | NA | NA | NA | ||||||||||||||
| VAL | C:153 | C:157 | 3.0 | 0.019 | -73.1 | 123.5 | NA | NA | NA | ||||||||||||||
| VAL | D:153 | D:157 | 2.0 | 0.013 | -79.9 | 121.4 | NA | NA | NA | ||||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | VAL | A:152 | I:157 | 20.0 | 0.129 | -82.2 | 126.8 | 20.0 | 0.129 | 0.0 | |||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | VAL | A:157 | A:175 | 3.0 | 0.019 | S | -136.2 | 155.9 | 3.0 | 0.019 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | VAL | A:157 | A:157 | 1.0 | 0.006 | S | -138.4 | 162.4 | 1.0 | 0.006 | 0.0 |
HOH |
3.918 |
CA |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | VAL | A:180 | A:180 | 8.0 | 0.052 | S | -130.7 | 157.6 | |