Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100775270 . C A CCDS5711.1:NM_000602.4:c.620aCc>aAc_NP_000593.1:p.207T>N Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 THR A:207 A:207 39.0 0.279 -77.5 112.9 39.0 0.279 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 THR A:184 A:184 115.0 0.821 T -101.5 -2.0 115.0 0.821 0.0 HOH
 2.622
 OG1
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 THR A:184 A:184 112.0 0.8 T -113.1 9.5 112.0 0.8 0.0 HOH
 2.573
 OG1
 O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 THR A:188 A:184 39.0 0.279 -73.4 131.2 39.0 0.279 0.0 HOH
 2.711
 OG1
 O
THR B:188 B:184 40.0 0.286 -72.3 133.6 NA NA NA
THR C:188 C:184 46.0 0.329 -69.9 123.3 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 THR A:184 A:184 32.0 0.229 -81.2 125.3 32.0 0.229 0.0 HOH
 2.923
 OG1
 O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 THR A:184 A:184 41.0 0.293 -95.4 138.0 41.0 0.293 0.0 HOH
 2.566
 OG1
 O
THR B:184 B:184 46.0 0.329 -70.5 125.5 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 THR A:184 A:184 38.0 0.271 -70.1 123.6 38.0 0.271 0.0 HOH
 2.761
 OG1
 O
THR B:184 B:184 40.0 0.286 -69.6 118.7 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 THR A:184 A:184 40.0 0.286 -71.6 125.5 40.0 0.286 0.0 HOH
 2.918
 OG1
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 THR A:184 A:184 63.0 0.45 -58.9 135.3 63.0 0.45 0.0 HOH
 2.738
 O
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 THR A:184 A:184 39.0 0.279 -67.8 122.0 39.0 0.279 0.0 HOH
 9.583
 N
 O
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 THR A:184 A:207 27.0 0.193 -113.4 124.4 27.0 0.193 0.0 HOH
 7.380
 OG1
 O
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 THR A:197 A:184 39.0 0.279 -80.5 129.8 39.0 0.279 0.0 HOH
 1.346
 HG1
 O
THR B:197 B:184 41.0 0.293 -82.2 137.0 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 THR A:184 A:184 38.0 0.271 -51.2 91.5 38.0 0.271 0.0
THR B:184 B:184 33.0 0.236 -49.4 91.1 NA NA NA
THR C:184 C:184 37.0 0.264 -50.4 90.8 NA NA NA
THR D:184 D:184 35.0 0.25 -48.8 90.2 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 THR A:184 A:184 32.0 0.229 -86.8 128.0 32.0 0.229 0.0 HOH
 2.837
 OG1
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 THR A:184 I:184 41.0 0.293 E -142.7 123.0 41.0 0.293 0.0 HOH
 5.138
 CG2
 O
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 THR A:184 A:184 32.0 0.229 -78.8 115.2 32.0 0.229 0.0
THR B:184 B:184 38.0 0.271 -71.2 122.0 NA NA NA
THR C:184 C:184 34.0 0.243 -66.8 122.9 NA NA NA
THR D:184 D:184 37.0 0.264 -80.0 112.3 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 THR A:184 A:184 23.0 0.164 -57.3 132.7 23.0 0.164 0.0 HOH
 2.983
 OG1
 O
THR B:184 B:184 28.0 0.2 -63.7 135.9 NA NA NA
THR C:184 C:184 37.0 0.264 -66.9 105.9 NA NA NA
THR D:184 D:184 42.0 0.3 -69.9 114.1 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 THR A:184 I:184 38.0 0.271 -78.3 115.5 38.0 0.271 0.0 HOH
 2.706
 O
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 THR A:184 A:184 37.0 0.264 -58.9 139.2 37.0 0.264 0.0
THR B:184 B:184 28.0 0.2 -72.4 121.3 NA NA NA
THR C:184 C:184 37.0 0.264 -71.0 133.0 NA NA NA
THR D:184 D:184 30.0 0.214 -82.2 120.7 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 THR A:184 A:184 36.0 0.257 -65.7 123.3 36.0 0.257 0.0 HOH
 2.954
 OG1
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 THR A:184 A:184 33.0 0.236 -87.0 120.8 33.0 0.236 0.0 HOH
 8.619
 CG2
 O
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 THR A:184 A:184 36.0 0.257 -69.3 135.5 36.0 0.257 0.0
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 THR A:184 A:184 36.0 0.257 -66.2 143.7 36.0 0.257 0.0 HOH
 2.701
 OG1
 O
THR B:184 B:184 37.0 0.264 -71.8 132.9 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 THR A:182 A:184 35.0 0.25 -75.0 123.9 22.0 0.157 0.093 B:P05121:0.093
THR B:182 B:184 36.0 0.257 -72.1 118.9 36.0 0.257 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 THR A:181 A:184 37.0 0.264 -71.3 118.6 37.0 0.264 0.0 HOH
 3.399
 O
 O
THR B:181 B:184 31.0 0.221 -75.8 120.0 NA NA NA
THR C:181 C:184 32.0 0.229 -68.3 121.9 NA NA NA
THR D:181 D:184 34.0 0.243 -74.2 122.9 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 THR A:181 A:184 24.0 0.171 -83.0 125.8 24.0 0.171 0.0 HOH
 2.669
 OG1
 O
THR B:181 B:184 39.0 0.279 -71.1 124.1 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 THR A:180 A:184 35.0 0.25 -65.0 138.6 35.0 0.25 0.0
THR B:180 B:184 39.0 0.279 -63.0 139.9 NA NA NA
THR C:180 C:184 40.0 0.286 -68.0 128.2 NA NA NA
THR D:180 D:184 31.0 0.221 -69.0 127.0 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 THR A:179 I:184 36.0 0.257 -66.6 108.6 36.0 0.257 0.0
9pai 1 P05121 99.71 0.0 X-RAY
 1999-03-19 THR A:184 A:202 38.0 0.271 -68.6 122.2 38.0 0.271 0.0
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 THR A:184 A:184 31.0 0.221 -78.7 135.4 31.0 0.221 0.0 HOH
 2.882
 OG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 THR A:207 A:207 28.0 0.2 -84.5 120.3