Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100775345 | . | A | C | CCDS5711.1:NM_000602.4:c.695aAc>aCc_NP_000593.1:p.232N>T | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | ASN | A:232 | A:232 | 36.0 | 0.225 | E | -67.6 | 136.0 | 36.0 | 0.225 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | ASN | A:209 | A:209 | 34.0 | 0.212 | E | -65.7 | 124.9 | 34.0 | 0.212 | 0.0 |
HOH |
2.720 |
N |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | ASN | A:209 | A:209 | 26.0 | 0.163 | E | -64.9 | 131.6 | 26.0 | 0.163 | 0.0 |
DMS HOH |
5.784 2.823 |
N OD1 |
C2 O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | ASN | A:213 | A:209 | 23.0 | 0.144 | E | -62.3 | 125.5 | 23.0 | 0.144 | 0.0 |
HOH |
4.430 |
ND2 |
O |
||
| ASN | B:213 | B:209 | 38.0 | 0.237 | E | -63.5 | 125.3 | NA | NA | NA | |||||||||||||
| ASN | C:213 | C:209 | 24.0 | 0.15 | E | -61.3 | 120.2 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | ASN | A:209 | A:209 | 50.0 | 0.312 | E | -71.7 | 123.5 | 50.0 | 0.312 | 0.0 |
NAG HOH |
1.484 2.836 |
ND2 N |
C1 O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ASN | A:209 | A:209 | 17.0 | 0.106 | E | -70.9 | 123.2 | 17.0 | 0.106 | 0.0 |
HOH |
3.091 |
N |
O |
||
| ASN | B:209 | B:209 | 19.0 | 0.119 | E | -62.8 | 128.3 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ASN | A:209 | A:209 | 24.0 | 0.15 | E | -68.6 | 122.1 | 24.0 | 0.15 | 0.0 |
HOH |
2.780 |
N |
O |
||
| ASN | B:209 | B:209 | 21.0 | 0.131 | E | -70.5 | 115.9 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | ASN | A:209 | A:209 | 25.0 | 0.156 | E | -62.4 | 123.9 | 25.0 | 0.156 | 0.0 |
HOH |
2.740 |
N |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | ASN | A:209 | A:209 | 18.0 | 0.113 | E | -65.5 | 125.5 | 18.0 | 0.113 | 0.0 |
HOH |
2.872 |
N |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | ASN | A:209 | A:209 | 28.0 | 0.175 | E | -62.5 | 117.6 | 28.0 | 0.175 | 0.0 | ||||||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | ASN | A:209 | A:232 | 59.0 | 0.369 | E | -70.9 | 129.4 | 59.0 | 0.369 | 0.0 |
NAG |
1.440 |
ND2 |
C1 |
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| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | ASN | A:222 | A:209 | 29.0 | 0.181 | E | -55.8 | 130.5 | 29.0 | 0.181 | 0.0 |
HOH |
2.040 |
H |
O |
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| ASN | B:222 | B:209 | 31.0 | 0.194 | E | -66.8 | 134.3 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | ASN | A:209 | A:209 | 34.0 | 0.212 | E | -69.8 | 107.4 | 34.0 | 0.212 | 0.0 | ||||||
| ASN | B:209 | B:209 | 33.0 | 0.206 | E | -70.7 | 106.8 | NA | NA | NA | |||||||||||||
| ASN | C:209 | C:209 | 36.0 | 0.225 | E | -69.7 | 105.9 | NA | NA | NA | |||||||||||||
| ASN | D:209 | D:209 | 35.0 | 0.219 | E | -71.6 | 106.4 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | ASN | A:209 | A:209 | 11.0 | 0.069 | -66.4 | 126.7 | 11.0 | 0.069 | 0.0 |
HOH |
2.822 |
N |
O |
|||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:209 | I:209 | 17.0 | 0.106 | E | -64.0 | 122.7 | 17.0 | 0.106 | 0.0 | ||||||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | ASN | A:209 | A:209 | 25.0 | 0.156 | E | -79.4 | 105.9 | 25.0 | 0.156 | 0.0 |
HOH |
9.048 |
N |
O |
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| ASN | B:209 | B:209 | 16.0 | 0.1 | E | -76.7 | 118.5 | NA | NA | NA | |||||||||||||
| ASN | C:209 | C:209 | 14.0 | 0.087 | E | -79.5 | 120.0 | NA | NA | NA | |||||||||||||
| ASN | D:209 | D:209 | 20.0 | 0.125 | E | -75.8 | 115.1 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | ASN | A:209 | A:209 | 35.0 | 0.219 | E | -90.0 | 106.9 | 35.0 | 0.219 | 0.0 |
HOH |
2.534 |
OD1 |
O |
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| ASN | B:209 | B:209 | 23.0 | 0.144 | E | -71.0 | 109.6 | NA | NA | NA | |||||||||||||
| ASN | C:209 | C:209 | 19.0 | 0.119 | E | -62.6 | 112.7 | NA | NA | NA | |||||||||||||
| ASN | D:209 | D:209 | 26.0 | 0.163 | E | -67.4 | 117.6 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | ASN | A:209 | I:209 | 32.0 | 0.2 | E | -56.8 | 125.8 | 32.0 | 0.2 | 0.0 |
HOH |
2.837 |
N |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | ASN | A:209 | A:209 | 36.0 | 0.225 | E | -63.7 | 119.0 | 36.0 | 0.225 | 0.0 | ||||||
| ASN | B:209 | B:209 | 37.0 | 0.231 | E | -55.3 | 119.2 | NA | NA | NA | |||||||||||||
| ASN | C:209 | C:209 | 24.0 | 0.15 | E | -57.9 | 112.6 | NA | NA | NA | |||||||||||||
| ASN | D:209 | D:209 | 40.0 | 0.25 | E | -57.2 | 116.8 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | ASN | A:209 | A:209 | 33.0 | 0.206 | E | -54.7 | 125.6 | 33.0 | 0.206 | 0.0 |
HOH |
2.754 |
N |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ASN | A:209 | A:209 | 31.0 | 0.194 | E | -79.6 | 121.8 | 31.0 | 0.194 | 0.0 |
HOH |
8.826 |
C |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ASN | A:209 | A:209 | 29.0 | 0.181 | E | -63.5 | 122.4 | 29.0 | 0.181 | 0.0 |
HOH |
2.887 |
N |
O |
||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | ASN | A:209 | A:209 | 39.0 | 0.244 | E | -61.0 | 127.5 | 39.0 | 0.244 | 0.0 |
HOH |
2.693 |
OD1 |
O |
||
| ASN | B:209 | B:209 | 26.0 | 0.163 | E | -66.3 | 123.4 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | ASN | A:207 | A:209 | 34.0 | 0.212 | E | -59.1 | 126.9 | 34.0 | 0.212 | 0.0 | ||||||
| ASN | B:207 | B:209 | 32.0 | 0.2 | E | -57.9 | 127.3 | 32.0 | 0.2 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ASN | A:206 | A:209 | 26.0 | 0.163 | E | -73.0 | 123.5 | 26.0 | 0.163 | 0.0 |
HOH |
5.227 |
OD1 |
O |
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| ASN | B:206 | B:209 | 14.0 | 0.087 | E | -72.2 | 115.1 | NA | NA | NA | |||||||||||||
| ASN | C:206 | C:209 | 26.0 | 0.163 | E | -74.9 | 106.8 | NA | NA | NA | |||||||||||||
| ASN | D:206 | D:209 | 40.0 | 0.25 | E | -74.5 | 110.6 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ASN | A:206 | A:209 | 29.0 | 0.181 | E | -65.9 | 117.4 | 29.0 | 0.181 | 0.0 |
HOH |
2.908 |
N |
O |
||
| ASN | B:206 | B:209 | 30.0 | 0.188 | E | -69.0 | 118.2 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | ASN | A:205 | A:209 | 32.0 | 0.2 | E | -56.4 | 119.7 | 32.0 | 0.2 | 0.0 | ||||||
| ASN | B:205 | B:209 | 15.0 | 0.094 | E | -62.1 | 114.4 | NA | NA | NA | |||||||||||||
| ASN | C:205 | C:209 | 29.0 | 0.181 | E | -65.7 | 118.2 | NA | NA | NA | |||||||||||||
| ASN | D:205 | D:209 | 27.0 | 0.169 | E | -55.2 | 119.9 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | ASN | A:204 | I:209 | 47.0 | 0.294 | E | -85.1 | 106.3 | 47.0 | 0.294 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | ASN | A:209 | A:227 | 30.0 | 0.188 | E | -76.0 | 103.0 | 30.0 | 0.188 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | ASN | A:209 | A:209 | 43.0 | 0.269 | E | -67.6 | 129.9 | 43.0 | 0.269 | 0.0 |
HOH |
2.758 |
N |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | ASN | A:232 | A:232 | 43.0 | 0.269 | E | -76.8 | 119.8 | |