Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100776988 | . | C | A | CCDS5711.1:NM_000602.4:c.713aCg>aAg_NP_000593.1:p.238T>K | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | THR | A:238 | A:238 | 1.0 | 0.007 | E | -64.3 | 145.6 | 1.0 | 0.007 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | THR | A:215 | A:215 | 4.0 | 0.029 | -75.8 | 174.2 | 4.0 | 0.029 | 0.0 |
HOH |
3.213 |
C |
O |
|||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | THR | A:215 | A:215 | 9.0 | 0.064 | -82.7 | 174.9 | 9.0 | 0.064 | 0.0 |
HOH |
2.773 |
OG1 |
O |
|||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | THR | A:219 | A:215 | 10.0 | 0.071 | -98.2 | 171.4 | 10.0 | 0.071 | 0.0 |
HOH |
2.755 |
O |
O |
|||
| THR | B:219 | B:215 | 9.0 | 0.064 | -88.3 | 175.7 | NA | NA | NA | ||||||||||||||
| THR | C:219 | C:215 | 9.0 | 0.064 | -87.2 | 164.4 | NA | NA | NA | ||||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | THR | A:215 | A:215 | 3.0 | 0.021 | -74.7 | 158.0 | 3.0 | 0.021 | 0.0 |
NAG NAG RIP HOH |
9.075 9.460 5.712 4.285 |
N C N CA |
O6 C8 O3 O |
|||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | THR | A:215 | A:215 | 5.0 | 0.036 | -74.0 | 160.6 | 5.0 | 0.036 | 0.0 |
HOH |
2.751 |
O |
O |
|||
| THR | B:215 | B:215 | 8.0 | 0.057 | -79.0 | 166.3 | NA | NA | NA | ||||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | THR | A:215 | A:215 | 1.0 | 0.007 | -75.6 | 160.0 | 1.0 | 0.007 | 0.0 |
HOH |
4.619 |
CA |
O |
|||
| THR | B:215 | B:215 | 7.0 | 0.05 | -70.7 | 164.3 | NA | NA | NA | ||||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | THR | A:215 | A:215 | 10.0 | 0.071 | -75.8 | 165.3 | 5.0 | 0.036 | 0.035 |
B:None:0.036 |
HOH |
6.982 |
N |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | THR | A:215 | A:215 | 11.0 | 0.079 | -79.6 | 162.9 | 11.0 | 0.079 | 0.0 |
HOH |
3.070 |
OG1 |
O |
|||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | THR | A:215 | A:215 | 11.0 | 0.079 | -67.7 | 161.5 | 7.0 | 0.05 | 0.029 |
B:None:0.029 |
HOH |
6.899 |
OG1 |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | THR | A:215 | A:238 | 5.0 | 0.036 | -58.2 | 157.0 | 5.0 | 0.036 | 0.0 |
NAG FUC |
9.292 6.210 |
N N |
O6 O3 |
|||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | THR | A:228 | A:215 | 7.0 | 0.05 | -71.2 | 167.3 | 7.0 | 0.05 | 0.0 |
HOH |
3.214 |
HB |
O |
|||
| THR | B:228 | B:215 | 8.0 | 0.057 | -84.6 | 172.8 | NA | NA | NA | ||||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | THR | A:215 | A:215 | 1.0 | 0.007 | E | -67.6 | 149.4 | 1.0 | 0.007 | 0.0 | ||||||
| THR | B:215 | B:215 | 1.0 | 0.007 | E | -68.9 | 149.5 | NA | NA | NA | |||||||||||||
| THR | C:215 | C:215 | 1.0 | 0.007 | E | -67.6 | 150.0 | NA | NA | NA | |||||||||||||
| THR | D:215 | D:215 | 1.0 | 0.007 | E | -68.5 | 149.4 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | THR | A:215 | A:215 | 6.0 | 0.043 | -78.3 | 164.6 | 6.0 | 0.043 | 0.0 |
HOH |
5.787 |
N |
O |
|||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | THR | A:215 | I:215 | 2.0 | 0.014 | E | -76.2 | 159.2 | 2.0 | 0.014 | 0.0 | ||||||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | THR | A:215 | A:215 | 5.0 | 0.036 | -91.7 | 162.5 | 5.0 | 0.036 | 0.0 | |||||||
| THR | B:215 | B:215 | 8.0 | 0.057 | -87.1 | 164.5 | NA | NA | NA | ||||||||||||||
| THR | C:215 | C:215 | 4.0 | 0.029 | -76.5 | 159.9 | NA | NA | NA | ||||||||||||||
| THR | D:215 | D:215 | 10.0 | 0.071 | -75.1 | 164.4 | NA | NA | NA | ||||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | THR | A:215 | A:215 | 4.0 | 0.029 | -87.5 | 157.2 | 4.0 | 0.029 | 0.0 |
HOH |
5.924 |
O |
O |
|||
| THR | B:215 | B:215 | 9.0 | 0.064 | -83.8 | 168.6 | NA | NA | NA | ||||||||||||||
| THR | C:215 | C:215 | 8.0 | 0.057 | -81.0 | 155.3 | NA | NA | NA | ||||||||||||||
| THR | D:215 | D:215 | 5.0 | 0.036 | -80.1 | 158.6 | NA | NA | NA | ||||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | THR | A:215 | I:215 | 7.0 | 0.05 | -70.6 | 165.0 | 7.0 | 0.05 | 0.0 |
HOH |
3.574 |
O |
O |
|||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | THR | A:215 | A:215 | 4.0 | 0.029 | -75.6 | 157.1 | 4.0 | 0.029 | 0.0 | |||||||
| THR | B:215 | B:215 | 4.0 | 0.029 | -84.5 | 162.3 | NA | NA | NA | ||||||||||||||
| THR | C:215 | C:215 | 5.0 | 0.036 | -72.0 | 158.4 | NA | NA | NA | ||||||||||||||
| THR | D:215 | D:215 | 3.0 | 0.021 | -74.3 | 162.7 | NA | NA | NA | ||||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | THR | A:215 | A:215 | 4.0 | 0.029 | -66.1 | 159.4 | 4.0 | 0.029 | 0.0 |
HOH |
7.444 |
O |
O |
|||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | THR | A:215 | A:215 | 13.0 | 0.093 | -60.5 | 165.8 | 9.0 | 0.064 | 0.029 |
B:None:0.029 |
HOH |
4.233 |
CB |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | THR | A:215 | A:215 | 5.0 | 0.036 | -71.7 | 163.0 | 0.0 | 0.0 | 0.036 |
B:None:0.036 |
HOH |
7.039 |
O |
O |
||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | THR | A:215 | A:215 | 8.0 | 0.057 | -77.1 | 165.1 | 8.0 | 0.057 | 0.0 |
HOH |
2.560 |
OG1 |
O |
|||
| THR | B:215 | B:215 | 4.0 | 0.029 | -66.9 | 157.8 | NA | NA | NA | ||||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | THR | A:213 | A:215 | 3.0 | 0.021 | -71.9 | 163.7 | 3.0 | 0.021 | 0.0 | |||||||
| THR | B:213 | B:215 | 3.0 | 0.021 | -70.2 | 167.9 | 3.0 | 0.021 | 0.0 | ||||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | THR | A:212 | A:215 | 2.0 | 0.014 | -88.3 | 156.3 | 2.0 | 0.014 | 0.0 | |||||||
| THR | B:212 | B:215 | 8.0 | 0.057 | -79.8 | 160.5 | NA | NA | NA | ||||||||||||||
| THR | C:212 | C:215 | 4.0 | 0.029 | -78.5 | 157.2 | NA | NA | NA | ||||||||||||||
| THR | D:212 | D:215 | 5.0 | 0.036 | -73.6 | 155.7 | NA | NA | NA | ||||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | THR | A:212 | A:215 | 7.0 | 0.05 | -79.7 | 166.3 | 7.0 | 0.05 | 0.0 |
HOH |
3.071 |
OG1 |
O |
|||
| THR | B:212 | B:215 | 3.0 | 0.021 | -71.6 | 158.5 | NA | NA | NA | ||||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | THR | A:211 | A:215 | 3.0 | 0.021 | -68.9 | 155.8 | 3.0 | 0.021 | 0.0 | |||||||
| THR | B:211 | B:215 | 6.0 | 0.043 | -78.9 | 164.0 | NA | NA | NA | ||||||||||||||
| THR | C:211 | C:215 | 5.0 | 0.036 | -67.4 | 157.9 | NA | NA | NA | ||||||||||||||
| THR | D:211 | D:215 | 5.0 | 0.036 | -75.5 | 167.6 | NA | NA | NA | ||||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | THR | A:210 | I:215 | 8.0 | 0.057 | -63.9 | 166.6 | 8.0 | 0.057 | 0.0 | |||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | THR | A:215 | A:233 | 6.0 | 0.043 | -97.4 | 152.7 | 6.0 | 0.043 | 0.0 | |||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | THR | A:215 | A:215 | 7.0 | 0.05 | -75.4 | 168.6 | 7.0 | 0.05 | 0.0 |
HOH |
3.689 |
CA |
O |
|||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | THR | A:238 | A:238 | 6.0 | 0.043 | -68.8 | 162.8 | ||